Michael C Heinrich

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 46

Top Topics

Renal Cell Carcinoma

Chronic Myeloid Leukemia

Top Venues

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Jorge E Cortes, Koiji Sasaki, Dong-Wook Kim, Timothy P Hughes, Gabriel Etienne, Michael J Mauro, Andreas Hochhaus, Fabian Lang, Michael C Heinrich, Massimo Breccia, Michael W Deininger, Yeow Tee Goh, Jeroen J W M Janssen, Moshe Talpaz, Valle Gomez Garcia de Soria, Philipp le Coutre, Daniel J DeAngelo, Andrea Damon, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Delphine Rea
Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results. Leukemia 38 (7) (2024)
Suzanne George, Jean Yves Blay, Ping Chi, Robin L Jones, Cesar Serrano, Neeta Somaiah, André B P van Kuilenburg, Zalcberg John, William Reichmann, Kam Sprott, Paulina Cox, Matthew L Sherman, Rodrigo Ruiz-Soto, Michael C Heinrich, Sebastian Bauer
The INSIGHT study: a randomized, Phase III study of ripretinib versus sunitinib for advanced gastrointestinal stromal tumor with KIT exon 11 + 17/18 mutations. Future oncology (London, England) (2024)
Jorge E Cortes, Koiji Sasaki, Dong-Wook Kim, Timothy P Hughes, Gabriel Etienne, Michael J Mauro, Andreas Hochhaus, Fabian Lang, Michael C Heinrich, Massimo Breccia, Michael W Deininger, Yeow Tee Goh, Jeroen J W M Janssen, Moshe Talpaz, Valle Gomez Garcia de Soria, Philipp le Coutre, Daniel J DeAngelo, Andrea Damon, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Delphine Rea
Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results. Leukemia 38 (7) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Jorge E Cortes, Koiji Sasaki, Dong-Wook Kim, Timothy P Hughes, Gabriel Etienne, Michael J Mauro, Andreas Hochhaus, Fabian Lang, Michael C Heinrich, Massimo Breccia, Michael W Deininger, Yeow Tee Goh, Jeroen J W M Janssen, Moshe Talpaz, Valle Gomez Garcia de Soria, Philipp le Coutre, Daniel J DeAngelo, Andrea Damon, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Delphine Rea
Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results. Leukemia 38 (7) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Jorge E Cortes, Koiji Sasaki, Dong-Wook Kim, Timothy P Hughes, Gabriel Etienne, Michael J Mauro, Andreas Hochhaus, Fabian Lang, Michael C Heinrich, Massimo Breccia, Michael W Deininger, Yeow Tee Goh, Jeroen J W M Janssen, Moshe Talpaz, Valle Gomez Garcia de Soria, Philipp le Coutre, Daniel J DeAngelo, Andrea Damon, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Delphine Rea
Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results. Leukemia (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Jorge E Cortes, Koiji Sasaki, Dong-Wook Kim, Timothy P Hughes, Gabriel Etienne, Michael J Mauro, Andreas Hochhaus, Fabian Lang, Michael C Heinrich, Massimo Breccia, Michael W Deininger, Yeow Tee Goh, Jeroen J W M Janssen, Moshe Talpaz, Valle Gomez Garcia de Soria, Philipp le Coutre, Daniel J DeAngelo, Andrea Damon, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Delphine Rea
Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results. Leukemia 38 (7) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine (2024)
Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz, Benjamin S Fletcher, Alina Teuber, Dawid Krzeciesa, Isabella Klooster, Meijun Z Lundberg, Lydia Wilson, Jonas Lategahn, Margaret von Mehren, Susanne Grunewald, Alicia Isabell Tüns, Eva Wardelmann, Jason K Sicklick, Mehdi Brahmi, César Serrano, Hans-Ulrich Schildhaus, Sonja Sievers, Jürgen Treckmann, Michael C Heinrich, Chandrajit P Raut, Wen-Bin Ou, Adrian Mariño-Enriquez, Suzanne George, Daniel Rauh, Jonathan A Fletcher, Sebastian Bauer
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (12) (2024)
Homma M Khosroyani, Lillian R Klug, Michael C Heinrich
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors. Drugs 83 (1) (2023)
Homma M Khosroyani, Lillian R Klug, Michael C Heinrich
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors. Drugs (2023)
Homma M Khosroyani, Lillian R Klug, Michael C Heinrich
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors. Drugs 83 (1) (2023)
Homma M Khosroyani, Lillian R Klug, Michael C Heinrich
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors. Drugs 83 (1) (2023)
Michael C Heinrich, Xinhua Zhang, Robin L Jones, Suzanne George, Cesar Serrano, Yan-Hong Deng, Sebastian Bauer, Shirong Cai, Xin Wu, Yongjian Zhou, Kaixiong Tao, Zhi-Chao Zheng, Jun Zhang, Yuehong Cui, Hui Cao, Meining Wang, Jin Hu, Jason Yang, Jian Li, Lin Shen
Clinical Benefit of Avapritinib in KIT-Mutant Gastrointestinal Stromal Tumors: A Post Hoc Analysis of the Phase I NAVIGATOR and Phase I/II CS3007-001 Studies. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Cesar Serrano, Sara Rothschild, Guillermo Villacampa, Michael C Heinrich, Suzanne George, Jean Yves Blay, Jason K Sicklick, Gary K Schwartz, Sameer Rastogi, Robin L Jones, Piotr Rutkowski, Neeta Somaiah, Víctor Navarro, Denisse Evans, Jonathan C Trent
Rethinking placebos: embracing synthetic control arms in clinical trials for rare tumors. Nature medicine (2023)
Homma M Khosroyani, Lillian R Klug, Michael C Heinrich
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors. Drugs 83 (1) (2023)
Suzanne George, Michael C Heinrich, Neeta Somaiah, Peter Oppelt, Robert McLeod, Satoshi Nishioka, Madan G Kundu, Xiaozhong Qian, Prasanna Kumar, Abderrahmane Laadem, Yvonne Lau, Brittany P Tran, Maura Fallon, Ololade Dosunmu, Julia Shi, Yoichi Naito
A Phase 1, Multicenter, Open-Label, First-in-Human Study of DS-6157a in Patients With Advanced Gastrointestinal Stromal Tumor. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Michael J Mauro, Timothy P Hughes, Dong-Wook Kim, Delphine Rea, Jorge E Cortes, Andreas Hochhaus, Koiji Sasaki, Massimo Breccia, Moshe Talpaz, Oliver Ottmann, Hironobu Minami, Yeow Tee Goh, Daniel J DeAngelo, Michael C Heinrich, Valle Gómez-García de Soria, Philipp le Coutre, Francois-Xavier Mahon, Jeroen J W M Janssen, Michael Deininger, Naranie Shanmuganathan, Mark Blaine Geyer, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Matthias Hoch, Fabian Lang
Asciminib monotherapy in patients with CML-CP without BCR::ABL1 T315I mutations treated with at least two prior TKIs: 4-year phase 1 safety and efficacy results. Leukemia (2023)
Homma M Khosroyani, Lillian R Klug, Michael C Heinrich
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors. Drugs 83 (1) (2023)
Sebastian Bauer, Robin L Jones, Jean Yves Blay, André B P van Kuilenburg, Suzanne George, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan C Trent, Steven Attia, Axel Le Cesne, Ying Su, Julie Meade, Tao Wang, Matthew L Sherman, Rodrigo Ruiz-Soto, Michael C Heinrich
Ripretinib Versus Sunitinib in Patients With Advanced Gastrointestinal Stromal Tumor After Treatment With Imatinib (INTRIGUE): A Randomized, Open-Label, Phase III Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (34) (2022)
Suzanne George, Margaret von Mehren, Jonathan A Fletcher, Jichao Sun, Sen Zhang, Justin R Pritchard, John Graeme Hodgson, David Kerstein, Victor M Rivera, Frank G Haluska, Michael C Heinrich
Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (7) (2022)
Lillian R Klug, Homma M Khosroyani, Jason D Kent, Michael C Heinrich
New treatment strategies for advanced-stage gastrointestinal stromal tumours. Nature reviews. Clinical oncology 19 (5) (2022)
Sebastian Bauer, Michael C Heinrich, Suzanne George, Zalcberg John, Cesar Serrano, André B P van Kuilenburg, Robin L Jones, Steven Attia, Gina D'Amato, Ping Chi, Peter Reichardt, Julie Meade, Ying Su, Rodrigo Ruiz-Soto, Jean Yves Blay, Margaret von Mehren, Patrick Schöffski
Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous KIT/PDGFRA Mutations in the Phase III INVICTUS Study. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (23) (2021)
Yoon-Koo Kang, Suzanne George, Robin L Jones, Piotr Rutkowski, Lin Shen, Olivier Mir, Shreyaskumar Patel, Yongjian Zhou, Margaret von Mehren, Peter Hohenberger, Victor M Villalobos, Mehdi Brahmi, William D Tap, Jonathan C Trent, Maria A Pantaleo, Patrick Schöffski, Kevin He, Paggy Hew, Kate Newberry, Maria Roche, Michael C Heinrich, Sebastian Bauer
Avapritinib Versus Regorafenib in Locally Advanced Unresectable or Metastatic GI Stromal Tumor: A Randomized, Open-Label Phase III Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (28) (2021)
Ashwyn K Sharma, Jorge de la Torre, Nikki S IJzerman, Thomas Lee Sutton, Beiqun Zhao, Tahsin M Khan, Sudeep Banerjee, Christina L Cui, Vi Nguyen, Maha Alkhuziem, Petur Snaebjornsson, Hester van Boven, Annemarie Bruining, Chih-Min Tang, Hyunho Yoon, Alexa De la Fuente, Shumei Kato, Hitendra Patel, Michael C Heinrich, Christopher L Corless, Santiago Horgan, Adam M Burgoyne, Paul Fanta, Jill P Mesirov, Andrew M Blakely, Jeremy Lee Davis, Skye C Mayo, Winan J van Houdt, Neeltje Steeghs, Jason K Sicklick
Location of Gastrointestinal Stromal Tumor (GIST) in the Stomach Predicts Tumor Mutation Profile and Drug Sensitivity. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Mayra Yebra, Shruti Bhargava, Avi Kumar, Adam M Burgoyne, Chih-Min Tang, Hyunho Yoon, Sudeep Banerjee, Joseph Aguilera, Thekla Cordes, Vipul R Sheth, Sangkyu Noh, Rowan Ustoy, Sam Li, Sunil J Advani, Christopher L Corless, Michael C Heinrich, Razelle Kurzrock, Scott M Lippman, Paul T Fanta, Olivier Harismendy, Christian Metallo, Jason K Sicklick
Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Lillian R Klug, Christopher L Corless, Michael C Heinrich
Inhibition of KIT Tyrosine Kinase Activity: Two Decades After the First Approval. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (15) (2021)
Hyunho Yoon, Chih-Min Tang, Sudeep Banerjee, Mayra Yebra, Sangkyu Noh, Adam M Burgoyne, Jorge De la Torre, Martina De Siena, Mengyuan Liu, Lillian R Klug, Yoon Young Choi, Mojgan Hosseini, Antonio L Delgado, Zhiyong Wang, Randall P French, Andrew Lowy, Ronald P DeMatteo, Michael C Heinrich, Alfredo A Molinolo, J Silvio Gutkind, Olivier Harismendy, Jason K Sicklick
Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis. Oncogene 40 (11) (2021)
Susanne Grunewald, Lillian R Klug, Thomas Mühlenberg, Jonas Lategahn, Johanna Falkenhorst, Ajia Town, Christiane Ehrt, Eva Wardelmann, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Juergen Treckmann, Jonathan A Fletcher, Sascha Jung, Paul Czodrowski, Stephen Miller, Oleg Schmidt-Kittler, Daniel Rauh, Michael C Heinrich, Sebastian Bauer
Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain. Cancer discovery 11 (1) (2020)
Jonathan Cohen, Alison Palumbo, Jason Wing, Michael C Heinrich
Case series of chronic myeloid leukemia patients who maintained deep molecular response (DMR) with very low-dose ponatinib: experience in discontinuing low-dose ponatinib and treatment-free remission (TFR) outcomes. Leukemia & lymphoma 61 (10) (2020)
César Serrano, Adrián Mariño-Enríquez, Derrick L Tao, Julia Ketzer, Grant Eilers, Meijun Zhu, Channing Yu, Aristotle M Mannan, Brian P Rubin, George D Demetri, Chandrajit P Raut, Ajia Presnell, Arin McKinley, Michael C Heinrich, Jeffrey T Czaplinski, Ewa Sicinska, Sebastian Bauer, Suzanne George, Jonathan A Fletcher
Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours. British journal of cancer 120 (6) (2019)
Jesus G Berdeja, Michael C Heinrich, Shaker R Dakhil, Stuart L Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge E Cortes, Jerald Radich, Bret Helton, David A Rizzieri, Carole Paley, Ilva Dautaj, Michael J Mauro
Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis. Leukemia & lymphoma 60 (10) (2019)
Michael C Heinrich, Janice Patterson, Carol Beadling, Yuexiang Wang, Maria Debiec-Rychter, Barbara Dewaele, Christopher L Corless, Anette Duensing, Chandrajit P Raut, Brian Rubin, Tamas Ordog, Matt van de Rijn, Jerry Call, Thomas Mühlenberg, Jonathan A Fletcher, Sebastian Bauer
Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs). Clinical sarcoma research 9 (2019)
Thomas Mühlenberg, Julia Ketzer, Michael C Heinrich, Susanne Grunewald, Adrian Marino-Enriquez, Marcel Trautmann, Wolfgang Hartmann, Eva Wardelmann, Jürgen Treckmann, Karl Worm, Stefanie Bertram, Thomas Herold, Hans-Ulrich Schildhaus, Hanno Glimm, Albrecht Stenzinger, Benedikt Brors, Peter Horak, Peter Hohenberger, Stefan Fröhling, Jonathan A Fletcher, Sebastian Bauer
KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy. Molecular cancer therapeutics 18 (11) (2019)
Erica K Evans, Alexandra K Gardino, Joseph L Kim, Brian L Hodous, Adam Shutes, Alison J Davis, Xing Julia Zhu, Oleg Schmidt-Kittler, Doug Wilson, Kevin Wilson, Lucian DiPietro, Yulian Zhang, Natasja Brooijmans, Timothy P LaBranche, Agnieszka Wozniak, Yemarshet K Gebreyohannes, Patrick Schöffski, Michael C Heinrich, Daniel J DeAngelo, Stephen Miller, Beni Wolf, Nancy E Kohl, Timothy Guzi, Nicholas Lydon, Andy Boral, Christoph Lengauer
A precision therapy against cancers driven by KIT/PDGFRA mutations. Science translational medicine 9 (414) (2018)