Michael Andreeff

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 81

Top Topics

Acute Myeloid Leukemia

Top Venues

Blood cancer journal

Cancer discovery

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

Branko Cuglievan, Hagop M Kantarjian, Jeffrey E Rubnitz, Todd M Cooper, C Michel Zwaan, Jessica A Pollard, Courtney D D DiNardo, Tapan Mahendra Kadia, Erin M Guest, Nicholas James Short, David C McCall, Naval G Daver, Cesar Nunez, Fadi G Haddad, Miriam B Garcia, Kapil N Bhalla, Abhishek Maiti, Samanta Catueno, Warren C Fiskus, Bing Z Carter, Amber Gibson, Michael Roth, Sajad Khazal, Priti Tewari, Hussein A Abbas, Wallace Bourgeois, Michael Andreeff, Neerav N Shukla, Danh D Truong, Jeremy Connors, Joseph A Ludwig, Janine Stutterheim, Elisabeth Salzer, Kristian L Juul-Dam, Koiji Sasaki, Kris M Mahadeo, Sarah K Tasian, Gautam Borthakur, Samantha Dickson, Nitin Jain, Elias J Jabbour, Soheil Meshinchi, Guillermo Garcia Manero, Farhad Ravandi, Eytan M Stein, E Anders Kolb, Ghayas C Issa
Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community. Leukemia (2024)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Correction: Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia (2024)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Correction: Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia (2024)
Mary Figueroa, Huaxian Ma, Mansour Alfayez, Daniel Enrique Morales-Mantilla, Fei Wang, Yue Lu, Marcos Estecio, Katherine Y King, Eugenie S Kleinerman, Seyed Javad Moghaddam, Naval G Daver, Michael Andreeff, Marina Y Konopleva, Courtney D D DiNardo, Joya Chandra
Cigarette smoke exposure accelerates AML progression in FLT3-ITD models. Blood advances (2023)
Jessica Ebner, Johannes Schmoellerl, Martin Piontek, Gabriele Manhart, Selina Troester, Bing Z Carter, Heidi A Neubauer, Richard H Moriggl, Gergely Szakács, Johannes Zuber, Thomas Köcher, Michael Andreeff, Wolfgang R Sperr, Peter Valent, Florian Grebien
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia. Nature communications 14 (1) (2023)
Alexandre Bazinet, Tapan M Kadia, Nicholas James Short, Gautam Borthakur, Sa A Wang, Wei Wang, Sanam Loghavi, Jeffrey L Jorgensen, Keyur Pravinchandra Patel, Courtney D D DiNardo, Naval G Daver, Yesid Alvarado, Fadi G Haddad, Sherry R Pierce, Graciela Nogueras Gonzalez, Abhishek Maiti, Koiji Sasaki, Musa Ylimaz, Phillip A Thompson, William G Wierda, Guillermo Garcia-Manero, Michael Andreeff, Elias J Jabbour, Marina Y Konopleva, Xuelin Huang, Hagop M Kantarjian, Farhad Ravandi
Undetectable Measurable Residual Disease is Associated with Improved Outcomes in AML Irrespective of Treatment Intensity. Blood advances (2023)
Yannan Jia, Weiguo Zhang, Mahesh Basyal, Kyung Hee Chang, Lauren B Ostermann, Jared K Burks, Charlie Ly, Hong Mu-Mosley, Qi Zhang, Xin Han, William E Fogler, John L Magnani, Arnaud Lesegretain, Anna A Zal, Tomasz Zal, Michael Andreeff
FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML. Leukemia (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia (2023)
Yannan Jia, Weiguo Zhang, Mahesh Basyal, Kyung Hee Chang, Lauren B Ostermann, Jared K Burks, Charlie Ly, Hong Mu-Mosley, Qi Zhang, Xin Han, William E Fogler, John L Magnani, Arnaud Lesegretain, Anna A Zal, Tomasz Zal, Michael Andreeff
FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML. Leukemia (2023)
Guopan Yu, Weiguo Zhang, Hongying Zhang, Charlie Ly, Mahesh Basyal, William G Rice, Michael Andreeff
The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and Aurora kinases. Research square (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia 38 (4) (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz, Lauren B Ostermann, Patrick P Lin, Bin Liu, Edward Ayoub, Jared K Burks, Michael Andreeff
Mdm2/p53 levels in bone marrow mesenchymal stromal cells are essential for maintaining the hematopoietic niche in response to DNA damage. Cell death & disease 14 (6) (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia 38 (4) (2023)
Jayastu Senapati, Muharrem Muftuoglu, Jo Ishizawa, Hussein A Abbas, Sanam Loghavi, Gautam Borthakur, Musa Ylimaz, Ghayas C Issa, Samuel I Dara, Mahesh Basyal, Li Li, Kiran Naqvi, Rasoul Pourebrahim, Elias J Jabbour, Steven Mitchell Kornblau, Nicholas James Short, Naveen Pemmaraju, Guillermo Garcia Manero, Farhad Ravandi, Joseph D Khoury, Naval G Daver, Hagop M Kantarjian, Michael Andreeff, Courtney D D DiNardo
A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis. Blood cancer journal 13 (1) (2023)
Bing Z Carter, Po Yee Mak, Muharrem Muftuoglu, Wenjing Tao, Ke Baozhen, Jingqi Pei, Andrea D Bedoy, Lauren B Ostermann, Yuki Nishida, Sevinj Isqandarova, Mary Sobieski, Nghi Nguyen, Reid T Powell, Margarita Martinez-Moczyemba, Clifford Stephen, Mahesh Basyal, Naveen Pemmaraju, Steffen Boettcher, Benjamin L Ebert, Elizabeth J Shpall, Barbara P Wallner, Robert Morgan, Georgios Ioannis Karras, Ute Moll, Michael Andreeff
Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells. Blood (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Yuki Nishida, Jo Ishizawa, Edward Ayoub, Rafael Heinz Montoya, Lauren B Ostermann, Muharrem Muftuoglu, Vivian R Ruvolo, Tallie Patsilevas, Darah A Scruggs, Shayaun Khazaei, Po Yee Mak, Wenjing Tao, Bing Z Carter, Steffen Boettcher, Benjamin L Ebert, Naval G Daver, Marina Konopleva, Takahiko Seki, Kensuke Kojima, Michael Andreeff
Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias. Science advances 9 (48) (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Jayastu Senapati, Muharrem Muftuoglu, Jo Ishizawa, Hussein A Abbas, Sanam Loghavi, Gautam Borthakur, Musa Ylimaz, Ghayas C Issa, Samuel I Dara, Mahesh Basyal, Li Li, Kiran Naqvi, Rasoul Pourebrahim, Elias J Jabbour, Steven Mitchell Kornblau, Nicholas James Short, Naveen Pemmaraju, Guillermo Garcia Manero, Farhad Ravandi, Joseph D Khoury, Naval G Daver, Hagop M Kantarjian, Michael Andreeff, Courtney D D DiNardo
A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis. Blood cancer journal 13 (1) (2023)
Seemana Bhattacharya, Sujan Piya, Huaxian Ma, Priyanka Sharma, Qi Zhang, Natalia Baran, Vivian R Ruvolo, Teresa McQueen, Richard Eric Davis, Rasoul Pourebrahim, Marina Y Konopleva, Hagop M Kantarjian, Nicholas D P Cosford, Michael Andreeff, Gautam Borthakur
Targeting Unc51-like Autophagy Activating Kinase 1 (ULK1) overcomes adaptive drug resistance in acute myelogenous leukemia. Molecular cancer research : MCR (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Yannan Jia, Weiguo Zhang, Mahesh Basyal, Kyung Hee Chang, Lauren B Ostermann, Jared K Burks, Charlie Ly, Hong Mu-Mosley, Qi Zhang, Xin Han, William E Fogler, John L Magnani, Arnaud Lesegretain, Anna A Zal, Tomasz Zal, Michael Andreeff
FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML. Leukemia (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Guopan Yu, Weiguo Zhang, Hongying Zhang, Charlie Ly, Mahesh Basyal, William G Rice, Michael Andreeff
The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and Aurora kinases. Research square (2023)
Guopan Yu, Weiguo Zhang, Hongying Zhang, Charlie Ly, Mahesh Basyal, William G Rice, Michael Andreeff
The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and Aurora kinases. Research square (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz, Lauren B Ostermann, Patrick P Lin, Bin Liu, Edward Ayoub, Jared K Burks, Michael Andreeff
Mdm2/p53 levels in bone marrow mesenchymal stromal cells is essential for maintaining the hematopoietic niche in response to DNA damage. Research square (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia 38 (4) (2023)
Yannan Jia, Weiguo Zhang, Mahesh Basyal, Kyung Hee Chang, Lauren B Ostermann, Jared K Burks, Charlie Ly, Hong Mu-Mosley, Qi Zhang, Xin Han, William E Fogler, John L Magnani, Arnaud Lesegretain, Anna A Zal, Tomasz Zal, Michael Andreeff
FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML. Leukemia (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis
Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer discovery (2023)
Jayastu Senapati, Muharrem Muftuoglu, Jo Ishizawa, Hussein A Abbas, Sanam Loghavi, Gautam Borthakur, Musa Ylimaz, Ghayas C Issa, Samuel I Dara, Mahesh Basyal, Li Li, Kiran Naqvi, Rasoul Pourebrahim, Elias J Jabbour, Steven Mitchell Kornblau, Nicholas James Short, Naveen Pemmaraju, Guillermo Garcia Manero, Farhad Ravandi, Joseph D Khoury, Naval G Daver, Hagop M Kantarjian, Michael Andreeff, Courtney D D DiNardo
A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis. Blood cancer journal 13 (1) (2023)
Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz, Lauren B Ostermann, Patrick P Lin, Bin Liu, Edward Ayoub, Jared K Burks, Michael Andreeff
Mdm2/p53 levels in bone marrow mesenchymal stromal cells is essential for maintaining the hematopoietic niche in response to DNA damage. Research square (2023)
Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz, Lauren B Ostermann, Patrick P Lin, Bin Liu, Edward Ayoub, Jared K Burks, Michael Andreeff
Mdm2/p53 levels in bone marrow mesenchymal stromal cells is essential for maintaining the hematopoietic niche in response to DNA damage. Research square (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia 38 (4) (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia 38 (4) (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Edward Ayoub, Lauren B Ostermann, Xuelin Huang, Sanam Loghavi, Steffen Boettcher, Yuki Nishida, Vivian Ruvolo, Paul E Hughes, Phuong K Morrow, Torsten Haferlach, Steven Mitchell Kornblau, Muharrem Muftuoglu, Michael Andreeff
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood cancer journal 13 (1) (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia (2023)
Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron David Schimmer, Michael Andreeff, Jo Ishizawa
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia 38 (4) (2023)
Bing Z Carter, Po Yee Mak, Wenjing Tao, Qi Zhang, Vivian Ruvolo, Vinitha M Kuruvilla, Xiangmeng Wang, Duncan H Mak, Venkata L Battula, Marina Konopleva, Elias J Jabbour, Paul E Hughes, Xiaoyue Chen, Phuong K Morrow, Michael Andreeff
Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic-Resistant AML and AML Stem Cells. Molecular cancer therapeutics 21 (6) (2022)
Sangeetha Venugopal, Koichi Takahashi, Naval G Daver, Abhishek Maiti, Gautam Borthakur, Sanam Loghavi, Nicholas James Short, Maro Ohanian, Lucia Masarova, Ghayas C Issa, Xuemei Wang, Bueso-Ramos Carlos, Musa Ylimaz, Tapan Mahendra Kadia, Michael Andreeff, Farhad Ravandi, Marina Y Konopleva, Hagop M Kantarjian, Courtney D D DiNardo
Efficacy and safety of enasidenib and azacitidine combination in patients with IDH2 mutated acute myeloid leukemia and not eligible for intensive chemotherapy. Blood cancer journal 12 (1) (2022)
Naval G Daver, Monique Dail, Jacqueline S Garcia, Brian A Jonas, Karen W L Yee, Kevin R Kelly, Norbert Vey, Sarit Assouline, Gail J Roboz, Stefania Paolini, Daniel A Pollyea, Agostino Tafuri, Joseph M Brandwein, Arnaud Pigneux, Bayard L Powell, Pierre Fenaux, Rebecca L Olin, Giuseppe Visani, Giovanni Martinelli, Maika Onishi, Jue Wang, Weize Huang, Cherie Green, Marion G Ott, Wan-Jen Hong, Marina Y Konopleva, Michael Andreeff
Venetoclax and idasanutlin in relapsed/refractory AML: a non-randomized, open-label phase 1b trial. Blood (2022)
Natalia Baran, Alessia Lodi, Yogesh Dhungana, Shelley Herbrich, Meghan E Collins, Shannon Sweeney, Renu Pandey, Anna Skwarska, Shraddha Patel, Mathieu Tremblay, Vinitha Mary Kuruvilla, Antonio Cavazos, Mecit Kaplan, Marc O Warmoes, Diogo Troggian Veiga, Ken Furudate, Shanti Rojas-Sutterin, Andre Haman, Yves Gareau, Anne Marinier, Helen Ma, Karine Harutyunyan, May Daher, Luciana Melo Garcia, Gheath Al-Atrash, Sujan Piya, Vivian Ruvolo, Wentao Yang, Sriram Saravanan Shanmugavelandy, Ningping Feng, Jason Gay, Di Du, Jun J Yang, Fieke W Hoff, Marcin Mikołaj Kamiński, Katarzyna Tomczak, Richard Eric Davis, Daniel Herranz, Adolfo A Ferrando, Elias J Jabbour, M Emilia Di Francesco, David Trent Teachey, Terzah M Horton, Steven Mitchell Kornblau, Katayoun Rezvani, Guy Sauvageau, Mihai Gagea, Michael Andreeff, Koichi Takahashi, Joseph R Marszalek, Philip L Lorenzi, Jiyang Yu, Stefano Tiziani, Trang Hoang, Marina Y Konopleva
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nature communications 13 (1) (2022)
Musa Ylimaz, Hagop M Kantarjian, Nicholas James Short, Patrick K Reville, Marina Y Konopleva, Tapan Mahendra Kadia, Courtney D D DiNardo, Gautam Borthakur, Naveen Pemmaraju, Abhishek Maiti, Elias J Jabbour, Nitin Jain, Ghayas C Issa, Koichi Takahashi, Koiji Sasaki, Maro Ohanian, Sherry Pierce, Guillin Tang, Sanam Loghavi, Keyur Pravinchandra Patel, Sa A Wang, Guillermo Garcia Manero, Michael Andreeff, Farhad Ravandi, Naval G Daver
Hypomethylating agent and venetoclax with FLT3 inhibitor "triplet" therapy in older/unfit patients with FLT3 mutated AML. Blood cancer journal 12 (5) (2022)
Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N Konoplev, Shannon R Sweeney, Jeremy Adam Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata Lokesh Battula, Yingchang Mi, Jing Wang, Courtney D DiNardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony G Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. Signal transduction and targeted therapy 7 (1) (2022)
Ghayas C Issa, Aram Bidikian, Sangeetha Venugopal, Marina Y Konopleva, Courtney D D DiNardo, Tapan M Kadia, Gautam Borthakur, Elias J Jabbour, Naveen Pemmaraju, Musa Yilmaz, Nicholas James Short, Abhishek Maiti, Koiji Sasaki, Lucia Masarova, Sherry R Pierce, Koichi Takahashi, Guilin Tang, Sanam Loghavi, Keyur Pravinchandra Patel, Michael Andreeff, Kapil N Bhalla, Guillermo Garcia-Manero, Farhad Ravandi, Hagop M Kantarjian, Naval G Daver
Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML. Blood advances (2022)
Courtney D D DiNardo, Curtis A Lachowiez, Koichi Takahashi, Sanam Loghavi, Tapan Mahendra Kadia, Naval G Daver, Lianchun Xiao, Maria Adeoti, Nicholas James Short, Koji Sasaki, Sa A Wang, Gautam Borthakur, Ghayas Issa, Abhishek Maiti, Yesid Alvarado, Naveen Pemmaraju, Guillermo Montalban Bravo, Lucia Masarova, Musa Ylimaz, Nitin Jain, Michael Andreeff, Guillermo Garcia Manero, Steven Kornblau, Farhad Ravandi, Elias J Jabbour, Marina Y Konopleva, Hagop M Kantarjian
Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed acute myeloid leukemia. American journal of hematology 97 (8) (2022)
Sujan Piya, Yaling Yang, Seemana Bhattacharya, Priyanka Sharma, Huaxian Ma, Hong Mu, Hua He, Vivian Ruvolo, Natalia Baran, Richard Eric Davis, Abhinav K Jain, Marina Y Konopleva, Hagop M Kantarjian, Michael Andreeff, Mingjian James You, Gautam Borthakur
Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL. Leukemia 36 (5) (2022)
Phillip A Thompson, Xianli Jiang, Pinaki Banerjee, Rafet Basar, Naveen Garg, Ken Chen, Mecit Kaplan, Vandana Nandivada, Ana Karen Nunez Cortes, Alessandra Ferrajoli, Michael J Keating, Christine B Peterson, Michael Andreeff, Katayoun Rezvani, William G Wierda
A phase two study of high dose blinatumomab in Richter's syndrome. Leukemia 36 (9) (2022)
Irene Gañán-Gómez, Hui Yang, Feiyang Ma, Guillermo Montalban-Bravo, Natthakan Thongon, Valentina Marchica, Guillaume Richard-Carpentier, Kelly Sharon Chien, Ganiraju C Manyam, Feng Wang, Ana Alfonso, Shuaitong Chen, Caleb A Class, Rashmi Kanagal-Shamana, Justin P Ingram, Yamini Ogoti, Ashley Rose, Sanam Loghavi, Pamela Lockyer, Benedetta Cambo, Muharrem Muftuoglu, Sarah M Schneider, Vera Adema, Michael D McLellan, John Garza, Matteo Marchesini, Nicola Giuliani, Matteo Pellegrini, Jing Wang, Jason R Walker, Ziyi Li, Koichi Takahashi, Joel D Leverson, Carlos Bueso-Ramos, Michael Andreeff, Karen Clise-Dwyer, Guillermo Garcia Manero, Simona Colla
Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. Nature medicine 28 (3) (2022)
Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N Konoplev, Shannon R Sweeney, Jeremy Adam Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata Lokesh Battula, Yingchang Mi, Jing Wang, Courtney D DiNardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony G Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. Signal transduction and targeted therapy 7 (1) (2022)
Ghayas C Issa, Jabra Zarka, Koji Sasaki, Wei Qiao, Daewoo Pak, Jing Ning, Nicholas James Short, Fadi Haddad, Zhenya Tang, Keyur Pravinchandra Patel, Branko Cuglievan, Naval G Daver, Courtney D D DiNardo, Elias J Jabbour, Tapan Mahendra Kadia, Gautam Borthakur, Guillermo Garcia Manero, Marina Y Konopleva, Michael Andreeff, Hagop M Kantarjian, Farhad Ravandi
Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements. Blood cancer journal 11 (9) (2021)
Claire Shao, Vivek Anand, Michael Andreeff, Venkata Lokesh Battula
Ganglioside GD2: a novel therapeutic target in triple-negative breast cancer. Annals of the New York Academy of Sciences (2021)
Jong Bok Lee, Dilshad H Khan, Rose Hurren, Mingjing Xu, Yoosu Na, Hyeonjeong Kang, Sara Mirali, Xiaoming Wang, Marcela Gronda, Yulia Jitkova, Neil MacLean, Andrea Arruda, Zoe Alaniz, Marina Y Konopleva, Michael Andreeff, Mark D Minden, Li Zhang, Aaron David Schimmer
Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production. Blood 138 (3) (2021)
Rashmi Kanagal-Shamana, Guillermo Montalban-Bravo, Panagiotis Katsonis, Koji Sasaki, Caleb A Class, Elias Jabbour, David A Sallman, Anthony Michael Hunter, Christopher Benton, Kelly S Chien, Rajyalakshmi Luthra, Carlos E Bueso-Ramos, Tapan Mahendra Kadia, Michael Andreeff, Rami S Komrokji, Najla H Al Ali, Nicholas James Short, Naval G Daver, Mark J Routbort, Joseph D Khoury, Keyur Pravinchandra Patel, Irene Ganan-Gomez, Yue Wei, Gautam Borthakur, Farhad Ravandi, Kim-Anh Do, Kelly A Soltysiak, Olivier Lichtarge, L Jeffrey Medeiros, Hagop M Kantarjian, Guillermo Garcia Manero
Evolutionary action score identifies a subset of TP53 mutated myelodysplastic syndrome with favorable prognosis. Blood cancer journal 11 (3) (2021)
Yuki Nishida, Ran Zhao, Lauren E Heese, Hiroki Akiyama, Shreya Patel, Alex M Jaeger, Rodrigo O Jacamo, Kensuke Kojima, Man Chun John Ma, Vivian R Ruvolo, Dhruv Chachad, William Devine, Susan Lindquist, R Eric Davis, John A Porco, Luke Whitesell, Michael Andreeff, Jo Ishizawa
Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML. Leukemia 35 (9) (2021)
Hussein A Abbas, Zoe Alaniz, Sean Mackay, Matthew Cyr, Jing Zhou, Ghayas C Issa, Mansour Alfayez, Jairo Matthews, Steven M Kornblau, Elias Jabbour, Guillermo Garcia-Manero, Marina Y Konopleva, Michael Andreeff, Naval G Daver
Single-cell polyfunctional proteomics of CD4 cells from patients with AML predicts responses to anti-PD-1-based therapy. Blood advances 5 (22) (2021)
Appalaraju Jaggupilli, Stanley Ly, Khoa Nguyen, Vivek Anand, Bin Yuan, Fouad El-Dana, Yuanqing Yan, Zoe Arvanitis, Danthasinghe Waduge Badrajee Piyarathna, Nagireddy Putluri, Helen Piwnica-Worms, Henry Charles Manning, Michael Andreeff, Venkata Lokesh Battula
Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer. British journal of cancer (2021)
Ghayas C Issa, Farhad Ravandi, Courtney D D DiNardo, Elias J Jabbour, Hagop M Kantarjian, Michael Andreeff
Therapeutic implications of menin inhibition in acute leukemias. Leukemia 35 (9) (2021)
Petra Gorombei, Fabien Guidez, Saravanan Ganesan, Mathieu Chiquet, Andrea Pellagatti, Laure Goursaud, Nilgun Tekin, Stephanie Beurlet, Satyananda Patel, Laura Guerenne, Carole Le Pogam, Niclas Setterblad, Pierre de la Grange, Christophe Leboeuf, Anne Janin, Maria-Elena Noguera, Laure Sarda-Mantel, Pascale Merlet, Jacqueline Boultwood, Marina Konopleva, Michael Andreeff, Robert West, Marika Pla, Lionel Adès, Pierre Fenaux, Patricia Krief, Christine Chomienne, Nader Omidvar, Rose Ann Padua
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome. International journal of molecular sciences 22 (19) (2021)
Kaori Saito, Qi Zhang, Haeun Yang, Kotoko Yamatani, Tomohiko Ai, Vivian R Ruvolo, Natalia Baran, Tianyu Cai, Helen Ma, Rodrigo Jacamo, Vinitha Kuruvilla, Junichi Imoto, Sonoko Kinjo, Kazuho Ikeo, Kaori Moriya, Koya Suzuki, Takashi Miida, Yong-Mi Kim, Christopher P Vellano, Michael Andreeff, Joseph R Marszalek, Yoko Tabe, Marina Y Konopleva
Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition. Blood advances 5 (20) (2021)
Bing Z Carter, Wenjing Tao, Po Yee Mak, Lauren B Ostermann, Duncan Mak, Gerard McGeehan, Peter Ordentlich, Michael Andreeff
Menin inhibition decreases Bcl-2 and synergizes with venetoclax in NPM1/FLT3-mutated AML. Blood 138 (17) (2021)
Francesca Lovat, Pierluigi Gasparini, Giovanni Nigita, Karilyn T M Larkin, John C Byrd, Mark D Minden, Michael Andreeff, Bing Z Carter, Carlo M Croce
Loss of expression of both miR-15/16 loci in CML transition to blast crisis. Proceedings of the National Academy of Sciences of the United States of America 118 (11) (2021)
Abhishek Maiti, Wei Qiao, Koiji Sasaki, Farhad Ravandi, Tapan Mahendra Kadia, Elias J Jabbour, Naval G Daver, Gautam Borthakur, Guillermo Garcia Manero, Sherry A Pierce, Kathryn S Montalbano, Naveen Pemmaraju, Kiran Naqvi, Maro Ohanian DO, Nicholas James Short, Yesid Alvarado, Koichi Takahashi, Musa Ylimaz, Nitin Jain, Steven M Kornblau, Michael Andreeff, Prithviraj Bose, Alessandra Ferrajoli, Ghayas C Issa, Lucia Masarova, Philip A Thompson, Caitlin R Rausch, Jing Ning, Hagop M Kantarjian, Courtney D D DiNardo, Marina Y Konopleva
Venetoclax with decitabine vs intensive chemotherapy in acute myeloid leukemia: A propensity score matched analysis stratified by risk of treatment-related mortality. American journal of hematology 96 (3) (2020)
Gautam Borthakur, Zhihong Zeng, Jorge E Cortes, Hsiang-Chun Chen, Xuelin Huang, Marina Y Konopleva, Farhad Ravandi, Tapan Mahendra Kadia, Keyur P Patel, Naval G Daver, Mary A Kelly, Teresa McQueen, Ru-Yiu Wang, Hagop M Kantarjian, Michael Andreeff
Phase 1 study of combinatorial sorafenib, G-CSF, and plerixafor treatment in relapsed/refractory, FLT3-ITD-mutated acute myelogenous leukemia patients. American journal of hematology 95 (11) (2020)
Xiangmeng Wang, Po Yee Mak, Hong Mu, Wenjing Tao, Arvind Rao, Ravikumar Visweswaran, Vivian Ruvolo, Jonathan A Pachter, David T Weaver, Michael Andreeff, Bing Xu, Bing Z Carter
Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia. Molecular cancer therapeutics 19 (8) (2020)
Bing Z Carter, Po Yee Mak, Xiangmeng Wang, Wenjing Tao, Vivian Ruvolo, Duncan Mak, Hong Mu, Jared K Burks, Michael Andreeff
An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML. Cancer research 79 (6) (2019)
Naval Daver, Guillermo Garcia-Manero, Sreyashi Basu, Prajwal C Boddu, Mansour Alfayez, Jorge E Cortes, Marina Konopleva, Farhad Ravandi-Kashani, Elias Jabbour, Tapan Kadia, Graciela M Nogueras-Gonzalez, Jing Ning, Naveen Pemmaraju, Courtney D DiNardo, Michael Andreeff, Sherry A Pierce, Tauna Gordon, Steven M Kornblau, Wilmer Flores, Zainab Alhamal, Carlos Bueso-Ramos, Jeffrey L Jorgensen, Keyur P Patel, Jorge Blando, James P Allison, Padmanee Sharma, Hagop Kantarjian
Efficacy, Safety, and Biomarkers of Response to Azacitidine and Nivolumab in Relapsed/Refractory Acute Myeloid Leukemia: A Nonrandomized, Open-Label, Phase II Study. Cancer discovery 9 (3) (2018)
Khoa Nguyen, Yuanqing Yan, Bin Yuan, Abhishek Dasgupta, Jeffrey Sun, Hong Mu, Kim-Anh Do, Naoto Tada Ueno, Michael Andreeff, V Lokesh Battula
ST8SIA1 Regulates Tumor Growth and Metastasis in TNBC by Activating the FAK-AKT-mTOR Signaling Pathway. Molecular cancer therapeutics 17 (12) (2018)
Ramiro Garzon, Michael R Savona, Rachid C Baz, Michael Andreeff, Nashat Gabrail, Martin Gutierrez, Lynn Savoie, Paul Morten Mau-Sorensen, Nina Wagner-Johnston, Karen Yee, Thaddeus J Unger, Jean-Richard Saint-Martin, Robert Carlson, Tami Rashal, Trinayan Kashyap, Boris Klebanov, Sharon Shacham, Michael Kauffman, Richard Stone
A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia. Blood 129 (24) (2017)
Rachel E Rau, Benjamin A Rodriguez, Min Luo, Mira Jeong, Allison Rosen, Jason H Rogers, Carly T Campbell, Scott R Daigle, Lishing Deng, Yongcheng Song, Steve Sweet, Timothy Chevassut, Michael Andreeff, Steven M Kornblau, Wei Li, Margaret A Goodell
DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood 128 (7) (2016)