Tom H M Ottenhoff (T H M Ottenhoff, Tom Ottenhoff)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 32

Top Topics

Randomized Controlled Trial

Listeria Monocytogenes

Positive Breast Cancer

Top Venues

Scientific reports

Nature microbiology

Microbiology spectrum

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Robin H G A van den Biggelaar, Kimberley V Walburg, Susan J F van den Eeden, Cassandra L R van Doorn, Eugenia Meiler, Alex S de Ries, M Chiara Fusco, Annemarie H Meijer, Tom H M Ottenhoff, Anno Saris
Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria. Scientific reports 14 (1) (2024)
Leela R L Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Stanley Kimbung Mbandi, Miguel Rodo, Tom H M Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Katharina Ronacher, Stefan H E Kaufmann, Elisa Nemes, Thomas Jens Scriba, Douglas A Lauffenburger, Galit Alter, Sarah M Fortune
Age and sex influence antibody profiles associated with tuberculosis progression. Nature microbiology (2024)
Robin H G A van den Biggelaar, Kimberley V Walburg, Susan J F van den Eeden, Cassandra L R van Doorn, Eugenia Meiler, Alex S de Ries, M Chiara Fusco, Annemarie H Meijer, Tom H M Ottenhoff, Anno Saris
Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria. Scientific reports 14 (1) (2024)
Gül Kilinç, Ralf Boland, Matthias T Heemskerk, Herman P Spaink, Marielle C Haks, Michiel Van Der Vaart, Tom H M Ottenhoff, Annemarie H Meijer, Anno Saris
Host-directed therapy with amiodarone in preclinical models restricts mycobacterial infection and enhances autophagy. Microbiology spectrum 12 (8) (2024)
Leela R L Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Stanley Kimbung Mbandi, Miguel Rodo, Tom H M Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Katharina Ronacher, Stefan H E Kaufmann, Elisa Nemes, Thomas Jens Scriba, Douglas A Lauffenburger, Galit Alter, Sarah M Fortune
Age and sex influence antibody profiles associated with tuberculosis progression. Nature microbiology 9 (6) (2024)
Krista E van Meijgaarden, Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Hans J P M Koenen, Leo A B Joosten, Annapurna Vyakarnam, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, Tom H M Ottenhoff, Yang Li, Mihai M Netea, Simone A Joosten
BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination. Nature communications 15 (1) (2024)
Krista E van Meijgaarden, Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Hans J P M Koenen, Leo A B Joosten, Annapurna Vyakarnam, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, Tom H M Ottenhoff, Yang Li, Mihai M Netea, Simone A Joosten
BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination. Nature communications 15 (1) (2024)
Leela R L Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Stanley Kimbung Mbandi, Miguel Rodo, Tom H M Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Katharina Ronacher, Stefan H E Kaufmann, Elisa Nemes, Thomas Jens Scriba, Douglas A Lauffenburger, Galit Alter, Sarah M Fortune
Age and sex influence antibody profiles associated with tuberculosis progression. Nature microbiology 9 (6) (2024)
Gül Kilinç, Ralf Boland, Matthias T Heemskerk, Herman P Spaink, Marielle C Haks, Michiel Van Der Vaart, Tom H M Ottenhoff, Annemarie H Meijer, Anno Saris
Host-directed therapy with amiodarone in preclinical models restricts mycobacterial infection and enhances autophagy. Microbiology spectrum (2024)
Leela R L Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Stanley Kimbung Mbandi, Miguel Rodo, Tom H M Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Katharina Ronacher, Stefan H E Kaufmann, Elisa Nemes, Thomas Jens Scriba, Douglas A Lauffenburger, Galit Alter, Sarah M Fortune
Age and sex influence antibody profiles associated with tuberculosis progression. Nature microbiology 9 (6) (2024)
Alexander T Bakker, Ioli Kotsogianni, Mariana Avalos, Jeroen M Punt, Bing Liu, Diana Piermarini, Berend Gagestein, Cornelis J Slingerland, Le Zhang, Joost J Willemse, Leela B Ghimire, Richard J H B N van den Berg, Antonius P A Janssen, Tom H M Ottenhoff, Constant A A van Boeckel, Gilles P van Wezel, Dmitry Ghilarov, Nathaniel I Martin, Mario van der Stelt
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nature chemistry (2024)
Leela R L Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Stanley Kimbung Mbandi, Miguel Rodo, Tom H M Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Katharina Ronacher, Stefan H E Kaufmann, Elisa Nemes, Thomas Jens Scriba, Douglas A Lauffenburger, Galit Alter, Sarah M Fortune
Age and sex influence antibody profiles associated with tuberculosis progression. Nature microbiology 9 (6) (2024)
Robin H G A van den Biggelaar, Kimberley V Walburg, Susan J F van den Eeden, Cassandra L R van Doorn, Eugenia Meiler, Alex S de Ries, M Chiara Fusco, Annemarie H Meijer, Tom H M Ottenhoff, Anno Saris
Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria. Scientific reports 14 (1) (2024)
Krista E van Meijgaarden, Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Hans J P M Koenen, Leo A B Joosten, Annapurna Vyakarnam, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, Tom H M Ottenhoff, Yang Li, Mihai M Netea, Simone A Joosten
BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination. Nature communications 15 (1) (2024)
Robin H G A van den Biggelaar, Kimberley V Walburg, Susan J F van den Eeden, Cassandra L R van Doorn, Eugenia Meiler, Alex S de Ries, M Chiara Fusco, Annemarie H Meijer, Tom H M Ottenhoff, Anno Saris
Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria. Scientific reports 14 (1) (2024)
Gül Kilinç, Ralf Boland, Matthias T Heemskerk, Herman P Spaink, Marielle C Haks, Michiel Van Der Vaart, Tom H M Ottenhoff, Annemarie H Meijer, Anno Saris
Host-directed therapy with amiodarone in preclinical models restricts mycobacterial infection and enhances autophagy. Microbiology spectrum (2024)
Sam Afkhami, Michael R D'Agostino, Maryam Vaseghi-Shanjani, Madeleine Lepard, Jack X Yang, Rocky Lai, Margaret Wa Yan Choi, Alexis Chacon, Anna Zganiacz, Kees L M C Franken, Hildegund C Ertl, Tom H M Ottenhoff, Mangalakumari Jeyanathan, Amy Gillgrass, Zhou Xing
Intranasal multivalent adenoviral-vectored vaccine protects against replicating and dormant M.tb in conventional and humanized mice. NPJ vaccines 8 (1) (2023)
Sam Afkhami, Michael R D'Agostino, Maryam Vaseghi-Shanjani, Madeleine Lepard, Jack X Yang, Rocky Lai, Margaret Wa Yan Choi, Alexis Chacon, Anna Zganiacz, Kees L M C Franken, Hildegund C Ertl, Tom H M Ottenhoff, Mangalakumari Jeyanathan, Amy Gillgrass, Zhou Xing
Intranasal multivalent adenoviral-vectored vaccine protects against replicating and dormant M.tb in conventional and humanized mice. NPJ vaccines 8 (1) (2023)
Srabanti Rakshit, Vasista Adiga, Asma Ahmed, Chaitra Parthiban, Nirutha Kumar, Sudarshan Shivalingaiah, Srishti Rao, George D'Souza, Pratibha Dwarkanath, Mary Dias, Thomas J A Maguire, Katie J Doores, Prokar Dasgupta, Sudhir Babji, Tom H M Ottenhoff, Kenneth Stuart, Stephen De Rosa, M Juliana McElrath, Annapurna Vyakarnam
BCG revaccination qualitatively and quantitatively enhances SARS-CoV-2 spike-specific neutralizing antibody and T cell responses induced by the COVISHIELDTM vaccine in SARS-CoV-2 seronegative young Indian adults. Research square (2022)
Ralf Boland, Matthias T Heemskerk, Gabriel Forn-Cuní, Cornelis J Korbee, Kimberley V Walburg, Jeroen J Esselink, Carina Carvalho Dos Santos, Amy M de Waal, Daniel C M van der Hoeven, Elisa van der Sar, Alex S de Ries, Jiajun Xie, Herman P Spaink, Michiel Van Der Vaart, Marielle C Haks, Annemarie H Meijer, Tom H M Ottenhoff
Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis. mBio (2022)
Paula Ruibal, Kees L M C Franken, Krista E van Meijgaarden, Marjolein van Wolfswinkel, Ian Derksen, Ferenc A Scheeren, George M C Janssen, Peter A van Veelen, Charlotte Sarfas, Andrew D White, Sally A Sharpe, Fabrizio Palmieri, Linda Petrone, Delia Goletti, Thomas Abeel, Tom H M Ottenhoff, Simone A Joosten
Identification of HLA-E Binding Mycobacterium tuberculosis -Derived Epitopes through Improved Prediction Models. Journal of immunology (Baltimore, Md. : 1950) 209 (8) (2022)
Mihaela Zlei, Igor A Sidorov, Simone A Joosten, Mirjam H M Heemskerk, Sebenzile K Myeni, Cilia R Pothast, Caroline S de Brouwer, A Linda Boomaars-van der Zanden, Krista E van Meijgaarden, Shessy T Morales, Els Wessels, Jacqueline J Janse, Jelle J Goeman, Christa M Cobbaert, Aloys C M Kroes, Suzanne C Cannegieter, Meta Roestenberg, Leonardus G Visser, Marjolein Kikkert, Mariet C W Feltkamp, Sesmu M Arbous, Frank J T Staal, Tom H M Ottenhoff, Jacques J M van Dongen, Anna H E Roukens, Jutte J C de Vries, null In Collaboration With Beat-Covid, null In Collaboration With Lumc Covid
Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance. Cells 11 (17) (2022)
M T Heemskerk, C J Korbee, J J Esselink, C Carvalho Dos Santos, S van Veen, I F Gordijn, F Vrieling, K V Walburg, C G Engele, K Dijkman, L Wilson, F A W Verreck, Tom H M Ottenhoff, M C Haks
Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections. Scientific reports 11 (1) (2021)
Gül Kilinç, Anno Saris, Tom H M Ottenhoff, Marielle C Haks
Host-directed therapy to combat mycobacterial infections. Immunological reviews 301 (1) (2021)
Francesco Santoro, Alessia Donato, Simone Lucchesi, Sara Sorgi, Alice Gerlini, Marielle C Haks, Tom H M Ottenhoff, Patricia Gonzalez-Dias, Vsv-Ebovac Consortium, Vsv-Eboplus Consortium, Helder Takashi Imoto Nakaya, Angela Huttner, Claire-Anne Siegrist, Donata Medaglini, Gianni Pozzi
Human Transcriptomic Response to the VSV-Vectored Ebola Vaccine. Vaccines 9 (2) (2021)
Zijie Zhou, Anouk van Hooij, Richard A W Vervenne, Claudia C Sombroek, Elisa M Tjon Kon Fat, Tom H M Ottenhoff, Paul Leo Albert Maria Corstjens, Frank Verreck, Annemieke Geluk
Quantitative Rapid Test for Detection and Monitoring of Active Pulmonary Tuberculosis in Nonhuman Primates. Biology 10 (12) (2021)
Mariateresa Coppola, Fabienne Jurion, Susan J F van den Eeden, Hermann Giresse Tima, Kees L M C Franken, Annemieke Geluk, Marta Romano, Tom H M Ottenhoff
In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination. NPJ vaccines 6 (1) (2021)
Paula Ruibal, Kees L M C Franken, Krista E van Meijgaarden, Joeri J F van Loon, Dirk van der Steen, Mirjam H M Heemskerk, Tom H M Ottenhoff, Simone A Joosten
Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues. Journal of immunology (Baltimore, Md. : 1950) 205 (10) (2020)
Lemmy Schakel, Dieuwke S Veldhuijzen, Henriët van Middendorp, Corine Prins, Anne M H F Drittij, Frank Vrieling, Leo G Visser, Tom H M Ottenhoff, Simone A Joosten, Andrea W M Evers
An Internet-Based Psychological Intervention With a Serious Game to Improve Vitality, Psychological and Physical Condition, and Immune Function in Healthy Male Adults: Randomized Controlled Trial. Journal of medical Internet research 22 (7) (2020)
Frank Vrieling, Louis Wilson, Patrick C N Rensen, Katharina Ronacher, Tom H M Ottenhoff, Simone A Joosten
Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction. PLoS pathogens 15 (4) (2019)
Bas C Mourik, Jurriaan E M de Steenwinkel, Gerjo J de Knegt, Ruth Huizinga, Annelies Verbon, Tom H M Ottenhoff, Dick van Soolingen, Pieter J M Leenen
Mycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37Rv. Scientific reports 9 (1) (2019)
Delia Goletti, Meng-Rui Lee, Ming-Chia Lee, Nicholas Walter, Tom H M Ottenhoff
Update on tuberculosis biomarkers: From correlates of risk, to correlates of active disease and of cure from disease. Respirology (Carlton, Vic.) 23 (5) (2018)