Neil Osheroff

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 57

Top Topics

Circulating Tumor

Staphylococcus Aureus

Top Venues

ACS infectious diseases

ACS medicinal chemistry letters

Medical science educator

This page only lists publications with an associated author ORCID identifier.

Publications

Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases (2024)
Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases 10 (4) (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff
Target-Mediated Fluoroquinolone Resistance in Neisseria gonorrhoeae : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff
Target-Mediated Fluoroquinolone Resistance in Neisseria gonorrhoeae : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV. ACS infectious diseases 10 (4) (2024)
Joshua W Powell, Chelsea A Mann, Paul D Toth, Sheri Nolan, Anja Steinert, Clarissa Ove, Justin T Seffernick, Daniel J Wozniak, Razieh Kebriaei, Steffen Lindert, Neil Osheroff, Jack C Yalowich, Mark J Mitton-Fry
Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening. ACS medicinal chemistry letters 15 (8) (2024)
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff
Target-Mediated Fluoroquinolone Resistance in Neisseria gonorrhoeae : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV. ACS infectious diseases 10 (4) (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff
Target-Mediated Fluoroquinolone Resistance in Neisseria gonorrhoeae : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases 10 (4) (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases 10 (4) (2024)
Joshua W Powell, Chelsea A Mann, Paul D Toth, Sheri Nolan, Anja Steinert, Clarissa Ove, Justin T Seffernick, Daniel J Wozniak, Razieh Kebriaei, Steffen Lindert, Neil Osheroff, Jack C Yalowich, Mark J Mitton-Fry
Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening. ACS medicinal chemistry letters 15 (8) (2024)
Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Neil Osheroff
Gyrase and Topoisomerase IV: Recycling Old Targets for New Antibacterials to Combat Fluoroquinolone Resistance. ACS infectious diseases 10 (4) (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Joshua W Powell, Chelsea A Mann, Paul D Toth, Sheri Nolan, Anja Steinert, Clarissa Ove, Justin T Seffernick, Daniel J Wozniak, Razieh Kebriaei, Steffen Lindert, Neil Osheroff, Jack C Yalowich, Mark J Mitton-Fry
Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening. ACS medicinal chemistry letters 15 (8) (2024)
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff
Target-Mediated Fluoroquinolone Resistance in Neisseria gonorrhoeae : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV. ACS infectious diseases 10 (4) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff
Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting. ACS infectious diseases 10 (4) (2024)
Joshua W Powell, Chelsea A Mann, Paul D Toth, Sheri Nolan, Anja Steinert, Clarissa Ove, Justin T Seffernick, Daniel J Wozniak, Razieh Kebriaei, Steffen Lindert, Neil Osheroff, Jack C Yalowich, Mark J Mitton-Fry
Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening. ACS medicinal chemistry letters 15 (8) (2024)
Jessica A Collins, Alexandria A Oviatt, Pan F Chan, Neil Osheroff
Target-Mediated Fluoroquinolone Resistance in Neisseria gonorrhoeae : Actions of Ciprofloxacin against Gyrase and Topoisomerase IV. ACS infectious diseases 10 (4) (2024)
Aviad Haramati, Giulia A Bonaminio, Neil Osheroff
Professional Identity Formation of Medical Science Educators: An Imperative for Academic Medicine. Medical science educator 34 (1) (2023)
Soziema E Dauda, Jessica A Collins, Jo Ann W Byl, Yanran Lu, Jack C Yalowich, Mark J Mitton-Fry, Neil Osheroff
Actions of a Novel Bacterial Topoisomerase Inhibitor against Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks. International journal of molecular sciences 24 (15) (2023)
Joseph E Deweese, Neil Osheroff
No Time to Relax and Unwind: Exploration of Topoisomerases and a Growing Field of Study. International journal of molecular sciences 24 (17) (2023)
Aviad Haramati, Giulia A Bonaminio, Neil Osheroff
Professional Identity Formation of Medical Science Educators: An Imperative for Academic Medicine. Medical science educator 34 (1) (2023)
Aviad Haramati, Giulia A Bonaminio, Neil Osheroff
Professional Identity Formation of Medical Science Educators: An Imperative for Academic Medicine. Medical science educator 34 (1) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jeffrey Y Jian, Kevin D McCarty, Jo Ann W Byl, F Peter Guengerich, Keir C Neuman, Neil Osheroff
Basis for the discrimination of supercoil handedness during DNA cleavage by human and bacterial type II topoisomerases. Nucleic acids research (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jeffrey Y Jian, Neil Osheroff
Telling Your Right Hand from Your Left: The Effects of DNA Supercoil Handedness on the Actions of Type II Topoisomerases. International journal of molecular sciences 24 (13) (2023)
Preshendren Govender, Rudolf Müller, Kawaljit Singh, Virsinha Reddy, Charles J Eyermann, Stephen Fienberg, Sandeep R Ghorpade, Lizbé Koekemoer, Alissa Myrick, Dirk Schnappinger, Curtis Engelhart, Jaclynn Meshanni, Jo Ann W Byl, Neil Osheroff, Vinayak Singh, Kelly Chibale, Gregory S Basarab
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity. Journal of medicinal chemistry 65 (9) (2022)
Esha D Dalvie, Jordan C Stacy, Keir C Neuman, Neil Osheroff
Recognition of DNA Supercoil Handedness during Catenation Catalyzed by Type II Topoisomerases. Biochemistry 61 (19) (2022)
Yanran Lu, Chelsea A Mann, Sheri Nolan, Jessica A Collins, Elizabeth Parker, Jonathan Papa, Sandip Vibhute, Seyedehameneh Jahanbakhsh, Mary Thwaites, David Hufnagel, Manzour H Hazbón, Jane Moreno, Timothy T Stedman, Thomas Wittum, Daniel J Wozniak, Neil Osheroff, Jack C Yalowich, Mark J Mitton-Fry
1,3-Dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Expanding Structural Diversity and the Antibacterial Spectrum. ACS medicinal chemistry letters 13 (6) (2022)
Sabrina X Van Ravenstein, Kavi P M Mehta, Tamar Kavlashvili, Jo Ann W Byl, Runxiang Zhao, Neil Osheroff, David Cortez, James M Dewar
Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms. The EMBO journal 41 (12) (2022)
Neil Osheroff
The COVID-19 Pandemic: a Year Lost, or a Year Found? Medical science educator (2021)
Eric D Huseman, Jo Ann W Byl, Scott M Chapp, Nathan D Schley, Neil Osheroff, Steven D Townsend
Synthesis and Cytotoxic Evaluation of Arimetamycin A and Its Daunorubicin and Doxorubicin Hybrids. ACS central science 7 (8) (2021)
Jessica A Collins, Neil Osheroff
1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases. Chemical research in toxicology 34 (4) (2021)
Kendra R Vann, Alexandria A Oviatt, Neil Osheroff
Topoisomerase II Poisons: Converting Essential Enzymes into Molecular Scissors. Biochemistry 60 (21) (2021)
Jose Antonio Ortega, Jose M Arencibia, Elirosa Minniti, Jo Ann W Byl, Sebastian Franco-Ulloa, Marco Borgogno, Vito Genna, Maria Summa, Sine Mandrup Bertozzi, Rosalia Bertorelli, Andrea Armirotti, Anna Minarini, Claudia Sissi, Neil Osheroff, Marco De Vivo
Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β. Journal of medicinal chemistry 63 (21) (2020)
Elizabeth G Gibson, Benjamin D Bax, Pan F Chan, Neil Osheroff
Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase. ACS infectious diseases 5 (4) (2019)
Jissy A Kuriappan, Neil Osheroff, Marco De Vivo
Smoothed Potential MD Simulations for Dissociation Kinetics of Etoposide To Unravel Isoform Specificity in Targeting Human Topoisomerase II. Journal of chemical information and modeling 59 (9) (2019)
Elizabeth G Gibson, Alexandria A Oviatt, Monica Cacho, Keir C Neuman, Pan F Chan, Neil Osheroff
Bimodal Actions of a Naphthyridone/Aminopiperidine-Based Antibacterial That Targets Gyrase and Topoisomerase IV. Biochemistry 58 (44) (2019)
Elizabeth G Gibson, Tim R Blower, Monica Cacho, Ben Bax, James M Berger, Neil Osheroff
Mechanism of Action of Mycobacterium tuberculosis Gyrase Inhibitors: A Novel Class of Gyrase Poisons. ACS infectious diseases 4 (8) (2018)
Rachel E Ashley, R Hunter Lindsey, Sylvia A McPherson, Charles L Turnbough, Robert J Kerns, Neil Osheroff
Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance. Biochemistry 56 (32) (2017)
Rachel E Ashley, Tim R Blower, James M Berger, Neil Osheroff
Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase. Biochemistry 56 (40) (2017)