Vinayak Singh

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Venues

ACS infectious diseases

Nature reviews. Chemistry

Journal of medicinal chemistry

Gates open research

University of Cape Town

Central Drug Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cape Town Jun 01 2020

South Africa

Senior Research Officer :: Chemistry

University of Cape Town Jan 01 2017 - May 31 2020

South Africa

Senior Investigator :: H3D Drug Discovery and Development Centre

Education History

Central Drug Research Institute Jul 25 2005 - Feb 25 2011

India

PHD :: Microbiology

Publications

Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases 10 (2) (2024)
Mousumi Shyam, Sumit Kumar, Vinayak Singh
Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans . ACS infectious diseases (2024)
Vinayak Singh, Godwin Akpeko Dziwornu, Kelly Chibale
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics. Nature reviews. Chemistry 7 (5) (2023)
Vinayak Singh, Godwin Akpeko Dziwornu, Kelly Chibale
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics. Nature reviews. Chemistry (2023)
Vinayak Singh, Godwin Akpeko Dziwornu, Kelly Chibale
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics. Nature reviews. Chemistry 7 (5) (2023)
Sauvik Samanta, Sumit Kumar, Eswar K Aratikatla, Sandeep R Ghorpade, Vinayak Singh
Recent developments of imidazo[1,2- a ]pyridine analogues as antituberculosis agents. RSC medicinal chemistry 14 (4) (2023)
Vinayak Singh, Godwin Akpeko Dziwornu, Kelly Chibale
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics. Nature reviews. Chemistry (2023)
Vinayak Singh, Godwin Akpeko Dziwornu, Kelly Chibale
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics. Nature reviews. Chemistry (2023)
Vinayak Singh, Godwin Akpeko Dziwornu, Kelly Chibale
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics. Nature reviews. Chemistry 7 (5) (2023)
Sauvik Samanta, Sumit Kumar, Eswar K Aratikatla, Sandeep R Ghorpade, Vinayak Singh
Recent developments of imidazo[1,2- a ]pyridine analogues as antituberculosis agents. RSC medicinal chemistry 14 (4) (2023)
Preshendren Govender, Rudolf Müller, Kawaljit Singh, Virsinha Reddy, Charles J Eyermann, Stephen Fienberg, Sandeep R Ghorpade, Lizbé Koekemoer, Alissa Myrick, Dirk Schnappinger, Curtis Engelhart, Jaclynn Meshanni, Jo Ann W Byl, Neil Osheroff, Vinayak Singh, Kelly Chibale, Gregory S Basarab
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity. Journal of medicinal chemistry 65 (9) (2022)
Alexander Berger, Talea Knak, Anna-Lene Kiffe-Delf, Korana Mudrovcic, Vinayak Singh, Mathew Njoroge, Bjoern Bengt Burckhardt, Mohanraj Gopalswamy, Beate Lungerich, Lutz Ackermann, Holger Gohlke, Kelly Chibale, Rainer Kalscheuer, Thomas Kurz
Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho -C(sp 2 )-H-Hydroxylation. Pharmaceuticals (Basel, Switzerland) 15 (8) (2022)
Vinayak Singh, Anna E Grzegorzewicz, Stephen Fienberg, Rudolf Müller, Lutete Peguy Khonde, Olalla Sanz, Salvatore Alfonso, Beatriz Urones, Gerard Drewes, Marcus Bantscheff, Sonja Ghidelli-Disse, Thomas R Ioerger, Bhanupriya Angala, Jiuyu Liu, Richard E Lee, James C Sacchettini, Inna V Krieger, Mary Jackson, Kelly Chibale, Sandeep R Ghorpade
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis . ACS infectious diseases 8 (11) (2022)
Nicole C Cardoso, Kelly Chibale, Vinayak Singh
Implications of Mycobacterium tuberculosis Metabolic Adaptability on Drug Discovery and Development. ACS infectious diseases 8 (3) (2022)
Gregory S Basarab, Sandeep Ghorpade, Liezl Gibhard, Rudolf Mueller, Mathew Njoroge, Nashied Peton, Preshendren Govender, Lisa M Massoudi, Gregory Thomas Robertson, Anne J Lenaerts, Helena Ingrid Boshoff, Douglas Joerss, Tanya Parish, Thomas F Durand-Reville, Manos Perros, Vinayak Singh, Kelly Chibale
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones. Antimicrobial agents and chemotherapy 66 (4) (2022)
Michael J Pepi, Shibin Chacko, Gary M Marqus, Vinayak Singh, Zhe Wang, Kyle Planck, Ryan T Cullinane, Penchala N Meka, Deviprasad R Gollapalli, Thomas R Ioerger, Kyu Y Rhee, Gregory D Cuny, Helena I M Boshoff, Lizbeth Hedstrom
A d-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis . ACS infectious diseases 8 (2) (2022)
Vinayak Singh, Dickson Mambwe, Constance Mawunyo Korkor, Kelly Chibale
Innovation Experiences from Africa-Led Drug Discovery at the Holistic Drug Discovery and Development (H3D) Centre. ACS medicinal chemistry letters 13 (8) (2022)
Dorothy Semenya, Meir Touitou, Camila Maringolo Ribeiro, Fernando Rogerio Pavan, Luca Pisano, Vinayak Singh, Kelly Chibale, Georg Bano, Anita Toscani, Fabrizio Manetti, Beatrice Gianibbi, Daniele Castagnolo
Structural Rigidification of N -Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria. ACS medicinal chemistry letters 13 (1) (2021)
Shibin Chacko, Helena I M Boshoff, Vinayak Singh, Davide M Ferraris, Deviprasad R Gollapalli, Minjia Zhang, Ann P Lawson, Michael J Pepi, Andrzej Joachimiak, Menico Rizzi, Valerie Mizrahi, Gregory D Cuny, Lizbeth Hedstrom
Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents. Journal of medicinal chemistry (2021)
Charles Omollo, Vinayak Singh, Elizabeth Kigondu, Antonina Wasuna, Pooja Agarwal, Atica Moosa, Thomas R Ioerger, Valerie Mizrahi, Kelly Chibale, Digby Francis Warner
Developing synergistic drug combinations to restore antibiotic sensitivity in drug-resistant Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy (2021)
Candice Soares de Melo, Vinayak Singh, Alissa Myrick, Sandile B Simelane, Dale Taylor, Christel Brunschwig, Nina Lawrence, Dirk Schnappinger, Curtis A Engelhart, Anuradha Kumar, Tanya Parish, Qin Su, Timothy G Myers, Helena I M Boshoff, Clifton E Barry, Frederick A Sirgel, Paul D van Helden, Kirsteen I Buchanan, Tracy Bayliss, Simon R Green, Peter C Ray, Paul G Wyatt, Gregory S Basarab, Charles J Eyermann, Kelly Chibale, Sandeep R Ghorpade
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies. Journal of medicinal chemistry 64 (1) (2021)
Vinayak Singh, Godwin Akpeko Dziwornu, Amanda Mabhula, Kelly Chibale
Rv0684/fusA1, an Essential Gene, Is the Target of Fusidic Acid and Its Derivatives in Mycobacterium tuberculosis. ACS infectious diseases 7 (8) (2021)
Lutete Peguy Khonde, Rudolf Müller, Grant A Boyle, Virsinha Reddy, Aloysius T Nchinda, Charles J Eyermann, Stephen Fienberg, Vinayak Singh, Alissa Myrick, Efrem Abay, Mathew Njoroge, Nina Lawrence, Qin Su, Timothy G Myers, Helena I M Boshoff, Clifton E Barry, Frederick A Sirgel, Paul D van Helden, Lisa M Massoudi, Gregory T Robertson, Anne J Lenaerts, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis. Journal of medicinal chemistry 64 (17) (2021)
Renier van der Westhuyzen, Amanda Mabhula, Paul M Njaria, Rudolf Müller, Denis Ngumbu Muhunga, Dale Taylor, Nina Lawrence, Mathew Njoroge, Christel Brunschwig, Atica Moosa, Vinayak Singh, Srinivasa P S Rao, Ujjini H Manjunatha, Paul W Smith, Digby F Warner, Leslie J Street, Kelly Chibale
Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging. Journal of medicinal chemistry 64 (13) (2021)
Karin Savková, Stanislav Huszár, Peter Baráth, Zuzana Pakanová, Stanislav Kozmon, Marie Vancová, Martina Tesařová, Jaroslav Blaško, Michal Kaliňák, Vinayak Singh, Jana Korduláková, Katarína Mikušová
An ABC transporter Wzm-Wzt catalyzes translocation of lipid-linked galactan across the plasma membrane in mycobacteria. Proceedings of the National Academy of Sciences of the United States of America 118 (17) (2021)
Vinayak Singh, Kelly Chibale
Strategies to Combat Multi-Drug Resistance in Tuberculosis. Accounts of chemical research 54 (10) (2021)
Rita Székely, Monica Rengifo-Gonzalez, Vinayak Singh, Olga Riabova, Andrej Benjak, Jérémie Piton, Mena Cimino, Etienne Kornobis, Valerie Mizrahi, Kai Johnsson, Giulia Manina, Vadim Makarov, Stewart Thomas Cole
6,11-Dioxobenzo[f]pyrido[1,2-a]indoles Kill Mycobacterium tuberculosis by Targeting Iron-Sulfur Protein Rv0338c (IspQ), A Putative Redox Sensor. ACS infectious diseases 6 (11) (2020)
Jessica N Akester, Paul Njaria, Aloysius Nchinda, Claire Le Manach, Alissa Myrick, Vinayak Singh, Nina Lawrence, Mathew Njoroge, Dale Taylor, Atica Moosa, Anthony J Smith, Elizabeth J Brooks, Anne J Lenaerts, Gregory T Robertson, Thomas R Ioerger, Rudolf Mueller, Kelly Chibale
Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity. ACS infectious diseases 6 (7) (2020)
Amanda Mabhula, Vinayak Singh
Drug-resistance in Mycobacterium tuberculosis: where we stand. MedChemComm 10 (8) (2019)
Benjamin Patterson, Charles Call, Vinayak Singh, Atica Moosa, Melitta Gqada, Jeremy Woodward, Valerie Mizrahi, Wayne Bryden, Charles Call, Shwetak Patel, Digby Francis Warner, Robin Wood
Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients. Gates open research (2018)
Benjamin Patterson, Jeremy D Woodward, Vinayak Singh, Atica Moosa, Melitta Gqada, Jeremy Woodward, Valerie Mizrahi, Wayne Bryden, Charles Call, Shwetak Patel, Digby Francis Warner, Robin Wood
Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients. Gates open research 1 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Vinayak Singh