Gregory S Basarab (Gregory Basarab)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 31

Top Topics

Plasmodium Falciparum

Top Venues

ACS infectious diseases

Journal of medicinal chemistry

Antimicrobial agents and chemotherapy

Macromolecular bioscience

This page only lists publications with an associated author ORCID identifier.

Publications

Godwin Akpeko Dziwornu, Tswene D Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S Sypu, Sauvik Samanta, Ashlyn D Bhana, Constance M Korkor, Larnelle F Garnie, Nicole Teixeira, Kathryn J Wicht, Dale Taylor, Ronald Olckers, Mathew Njoroge, Liezl Gibhard, Nicolaas Salomane, Sergio Wittlin, Rohit Mahato, Arnish Chakraborty, Nicole Sevilleno, Rachael Coyle, Marcus C S Lee, Luiz C Godoy, Charisse Flerida Pasaje, Jacquin C Niles, Janette Reader, Mariette van der Watt, Lyn-Marié Birkholtz, Judith M Bolscher, Marloes H C de Bruijni, Lauren B Coulson, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy. Journal of medicinal chemistry 67 (13) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Godwin Akpeko Dziwornu, Tswene D Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S Sypu, Sauvik Samanta, Ashlyn D Bhana, Constance M Korkor, Larnelle F Garnie, Nicole Teixeira, Kathryn J Wicht, Dale Taylor, Ronald Olckers, Mathew Njoroge, Liezl Gibhard, Nicolaas Salomane, Sergio Wittlin, Rohit Mahato, Arnish Chakraborty, Nicole Sevilleno, Rachael Coyle, Marcus C S Lee, Luiz C Godoy, Charisse Flerida Pasaje, Jacquin C Niles, Janette Reader, Mariette van der Watt, Lyn-Marié Birkholtz, Judith M Bolscher, Marloes H C de Bruijni, Lauren B Coulson, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy. Journal of medicinal chemistry 67 (13) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases (2024)
Liezl Gibhard, Mathew Njoroge, Mwila Mulubwa, Nina Lawrence, Dennis Smith, James Duffy, Claire Le Manach, Christel Brunschwig, Dale Taylor, Renier van der Westhuyzen, Leslie J Street, Gregory S Basarab, Kelly Chibale
Dose-fractionation studies of a Plasmodium phosphatidylinositol 4-kinase inhibitor in a humanized mouse model of malaria. Antimicrobial agents and chemotherapy (2024)
Godwin Akpeko Dziwornu, Tswene D Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S Sypu, Sauvik Samanta, Ashlyn D Bhana, Constance M Korkor, Larnelle F Garnie, Nicole Teixeira, Kathryn J Wicht, Dale Taylor, Ronald Olckers, Mathew Njoroge, Liezl Gibhard, Nicolaas Salomane, Sergio Wittlin, Rohit Mahato, Arnish Chakraborty, Nicole Sevilleno, Rachael Coyle, Marcus C S Lee, Luiz C Godoy, Charisse Flerida Pasaje, Jacquin C Niles, Janette Reader, Mariette van der Watt, Lyn-Marié Birkholtz, Judith M Bolscher, Marloes H C de Bruijni, Lauren B Coulson, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy. Journal of medicinal chemistry 67 (13) (2024)
Godwin Akpeko Dziwornu, Tswene D Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S Sypu, Sauvik Samanta, Ashlyn D Bhana, Constance M Korkor, Larnelle F Garnie, Nicole Teixeira, Kathryn J Wicht, Dale Taylor, Ronald Olckers, Mathew Njoroge, Liezl Gibhard, Nicolaas Salomane, Sergio Wittlin, Rohit Mahato, Arnish Chakraborty, Nicole Sevilleno, Rachael Coyle, Marcus C S Lee, Luiz C Godoy, Charisse Flerida Pasaje, Jacquin C Niles, Janette Reader, Mariette van der Watt, Lyn-Marié Birkholtz, Judith M Bolscher, Marloes H C de Bruijni, Lauren B Coulson, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy. Journal of medicinal chemistry 67 (13) (2024)
Godwin Akpeko Dziwornu, Tswene D Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S Sypu, Sauvik Samanta, Ashlyn D Bhana, Constance M Korkor, Larnelle F Garnie, Nicole Teixeira, Kathryn J Wicht, Dale Taylor, Ronald Olckers, Mathew Njoroge, Liezl Gibhard, Nicolaas Salomane, Sergio Wittlin, Rohit Mahato, Arnish Chakraborty, Nicole Sevilleno, Rachael Coyle, Marcus C S Lee, Luiz C Godoy, Charisse Flerida Pasaje, Jacquin C Niles, Janette Reader, Mariette van der Watt, Lyn-Marié Birkholtz, Judith M Bolscher, Marloes H C de Bruijni, Lauren B Coulson, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy. Journal of medicinal chemistry (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
Jessica A Collins, Gregory S Basarab, Kelly Chibale, Neil Osheroff
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting. ACS infectious diseases 10 (8) (2024)
John G Woodland, Gregory S Basarab, Koketso Mogwera, Susan Winks, Kelly Chibale
The 2022 H3D Symposium: Celebrating over a Decade of African-Led Infectious Disease Drug Discovery to Enhance Global Health. ACS infectious diseases (2023)
John G Woodland, Gregory S Basarab, Koketso Mogwera, Susan Winks, Kelly Chibale
The 2022 H3D Symposium: Celebrating over a Decade of African-Led Infectious Disease Drug Discovery to Enhance Global Health. ACS infectious diseases 9 (3) (2023)
William M R Matshe, Lesego L Tshweu, Sindisiwe Mvango, Zamani E D Cele, Avashnee S Chetty, Lynne Alison Pilcher, Ibukun Michael Famuyide, Lyndy Joy McGaw, Dale Taylor, Liezl Gibhard, Gregory S Basarab, Mohammed O Balogun
A Water-Soluble Polymer-Lumefantrine Conjugate for the Intravenous Treatment of Severe Malaria. Macromolecular bioscience (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Diego González Cabrera, Dennis A Smith, Gregory S Basarab, James Duffy, Thomas Spangenberg, Kelly Chibale
Anti-infectives Developed as Racemic Drugs in the 21st Century: Norm or Exception? ACS medicinal chemistry letters 14 (7) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
John G Woodland, Gregory S Basarab, Koketso Mogwera, Susan Winks, Kelly Chibale
The 2022 H3D Symposium: Celebrating over a Decade of African-Led Infectious Disease Drug Discovery to Enhance Global Health. ACS infectious diseases 9 (3) (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases (2023)
Jo Ann W Byl, Rudolf Mueller, Benjamin D Bax, Gregory S Basarab, Kelly Chibale, Neil Osheroff
A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase. ACS infectious diseases 9 (3) (2023)
Preshendren Govender, Rudolf Müller, Kawaljit Singh, Virsinha Reddy, Charles J Eyermann, Stephen Fienberg, Sandeep R Ghorpade, Lizbé Koekemoer, Alissa Myrick, Dirk Schnappinger, Curtis Engelhart, Jaclynn Meshanni, Jo Ann W Byl, Neil Osheroff, Vinayak Singh, Kelly Chibale, Gregory S Basarab
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity. Journal of medicinal chemistry 65 (9) (2022)
Lauren B Arendse, Gyles E Cozier, Charles J Eyermann, Gregory S Basarab, Sylva L Schwager, Kelly Chibale, K Ravi Acharya, Edward D Sturrock
Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. Journal of medicinal chemistry 65 (4) (2022)
Gregory S Basarab, Sandeep Ghorpade, Liezl Gibhard, Rudolf Mueller, Mathew Njoroge, Nashied Peton, Preshendren Govender, Lisa M Massoudi, Gregory Thomas Robertson, Anne J Lenaerts, Helena Ingrid Boshoff, Douglas Joerss, Tanya Parish, Thomas F Durand-Reville, Manos Perros, Vinayak Singh, Kelly Chibale
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones. Antimicrobial agents and chemotherapy 66 (4) (2022)
Candice Soares de Melo, Vinayak Singh, Alissa Myrick, Sandile B Simelane, Dale Taylor, Christel Brunschwig, Nina Lawrence, Dirk Schnappinger, Curtis A Engelhart, Anuradha Kumar, Tanya Parish, Qin Su, Timothy G Myers, Helena I M Boshoff, Clifton E Barry, Frederick A Sirgel, Paul D van Helden, Kirsteen I Buchanan, Tracy Bayliss, Simon R Green, Peter C Ray, Paul G Wyatt, Gregory S Basarab, Charles J Eyermann, Kelly Chibale, Sandeep R Ghorpade
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies. Journal of medicinal chemistry 64 (1) (2021)
Lutete Peguy Khonde, Rudolf Müller, Grant A Boyle, Virsinha Reddy, Aloysius T Nchinda, Charles J Eyermann, Stephen Fienberg, Vinayak Singh, Alissa Myrick, Efrem Abay, Mathew Njoroge, Nina Lawrence, Qin Su, Timothy G Myers, Helena I M Boshoff, Clifton E Barry, Frederick A Sirgel, Paul D van Helden, Lisa M Massoudi, Gregory T Robertson, Anne J Lenaerts, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis. Journal of medicinal chemistry 64 (17) (2021)
Claire Le Manach, Jean Dam, John G Woodland, Gurminder Kaur, Lutete P Khonde, Christel Brunschwig, Mathew Njoroge, Kathryn J Wicht, André Horatscheck, Tanya Paquet, Grant A Boyle, Liezl Gibhard, Dale Taylor, Nina Lawrence, Tomas Yeo, Sachel Mok, Richard T Eastman, Dorjbal Dorjsuren, Daniel C Talley, Hui Guo, Anton Simeonov, Janette Reader, Mariëtte van der Watt, Erica Erlank, Nelius Venter, Jacek W Zawada, Ayesha Aswat, Luisa Nardini, Theresa L Coetzer, Sonja B Lauterbach, Belinda C Bezuidenhout, Anjo Theron, Dalu Mancama, Lizette L Koekemoer, Lyn-Marie Birkholtz, Sergio Wittlin, Michael Delves, Sabine Ottilie, Elizabeth A Winzeler, Thomas W von Geldern, Dennis Smith, David A Fidock, Leslie J Street, Gregory S Basarab, James Duffy, Kelly Chibale
Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts. Journal of medicinal chemistry 64 (4) (2021)
Janette Reader, Mariëtte E van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Sabine Ottilie, Anjo Theron, Phanankosi Moyo, Erica Erlank, Luisa Nardini, Nelius Venter, Sonja Lauterbach, Belinda Bezuidenhout, André Horatscheck, Ashleigh van Heerden, Natalie J Spillman, Anne N Cowell, Jessica Connacher, Daniel Opperman, Lindsey M Orchard, Manuel Llinás, Eva S Istvan, Daniel E Goldberg, Grant A Boyle, David Calvo, Dalu Mancama, Theresa L Coetzer, Elizabeth A Winzeler, James Duffy, Lizette Leonie Koekemoer, Gregory S Basarab, Kelly Chibale, Lyn-Marié Birkholtz
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box. Nature communications 12 (1) (2021)
Stephen Fienberg, Charles J Eyermann, Lauren B Arendse, Gregory S Basarab, Jacob A McPhail, John E Burke, Kelly Chibale
Structural Basis for Inhibitor Potency and Selectivity of Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors. ACS infectious diseases 6 (11) (2020)
Gregory S Basarab, Peter Doig, Charles J Eyermann, Vincent Galullo, Gunther Kern, Amy Kimzey, Amy Kutschke, Marshall Morningstar, Virna Schuck, Karthick Vishwanathan, Fei Zhou, Madhusudhan Gowravaram, Sheila Hauck
Antibacterial Spiropyrimidinetriones with N-Linked Azole Substituents on a Benzisoxazole Scaffold Targeting DNA Gyrase. Journal of medicinal chemistry 63 (20) (2020)