Christian W Gruber

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Venues

Planta medica

RSC chemical biology

Journal of medicinal chemistry

Journal of natural products

Medical University of Vienna

University of Queensland (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Medical University of Vienna Jan 01 2018

Austria

Associate Professor :: Center for Physiology and Pharmacology

The University of Queensland Aug 03 2015 - Feb 15 2018

Australia

ARC Future Fellow :: School of Biomedical Sciences

Medical University of Vienna

Austria

Assistant Professor :: Institute for Pharmacology

University of Vienna

Austria

PostDoc :: Department of Pharmacognosy

Medical University of Vienna

Austria

PostDoc, Lise-Meitner Fellow :: Institute for Pharmacology

Education History

University of Queensland

Australia

PHD :: Institute for Molecular Bioscience

Queensland University of Technology

Australia

BSC :: School of Life Sciences

Publications

Christian W Gruber
Plant-Derived Peptides: (Neglected) Natural Products for Drug Discovery. Planta medica 90 (7-08) (2024)
Miroslav Kosar, Roman C Sarott, David A Sykes, Alexander E G Viray, Rosa Maria Vitale, Nataša Tomašević, Xiaoting Li, Rudolf L Z Ganzoni, Bilal Kicin, Lisa Reichert, Kacper J Patej, Uxía Gómez-Bouzó, Wolfgang Guba, Peter J McCormick, Tian Hua, Christian W Gruber, Dmitry B Veprintsev, James Allen Frank, Uwe Grether, Erick M Carreira
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists. ACS central science 10 (5) (2024)
Christian W Gruber
Plant-Derived Peptides: (Neglected) Natural Products for Drug Discovery. Planta medica 90 (7-08) (2024)
Christian W Gruber
Plant-Derived Peptides: (Neglected) Natural Products for Drug Discovery. Planta medica 90 (7-08) (2024)
Miroslav Kosar, Roman C Sarott, David A Sykes, Alexander E G Viray, Rosa Maria Vitale, Nataša Tomašević, Xiaoting Li, Rudolf L Z Ganzoni, Bilal Kicin, Lisa Reichert, Kacper J Patej, Uxía Gómez-Bouzó, Wolfgang Guba, Peter J McCormick, Tian Hua, Christian W Gruber, Dmitry B Veprintsev, James Allen Frank, Uwe Grether, Erick M Carreira
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists. ACS central science 10 (5) (2024)
Johannes Koehbach, Edin Muratspahić, Zakaria M Ahmed, Andrew M White, Nataša Tomašević, Thomas Durek, Richard J Clark, Christian W Gruber, David J Craik
Chemical synthesis of grafted cyclotides using a "plug and play" approach. RSC chemical biology 5 (6) (2024)
Johannes Koehbach, Edin Muratspahić, Zakaria M Ahmed, Andrew M White, Nataša Tomašević, Thomas Durek, Richard J Clark, Christian W Gruber, David J Craik
Chemical synthesis of grafted cyclotides using a "plug and play" approach. RSC chemical biology 5 (6) (2024)
Francesca Nuti, Maud Larregola, Agnieszka Staśkiewicz, Bernhard Retzl, Nataša Tomašević, Lorenzo Macchia, Maria Elisabeth Street, Michał Paweł Jewgiński, Olivier Lequin, Rafał Latajka, Paolo Rovero, Christian W Gruber, Michael Chorev, Anna Maria Papini
Design, synthesis, conformational analysis, and biological activity of Cα 1 -to-Cα 6 1,4- and 4,1-disubstituted 1 H -[1,2,3]triazol-1-yl-bridged oxytocin analogues. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Edin Muratspahić, Kristine Deibler, Jianming Han, Nataša Tomašević, Kirtikumar B Jadhav, Aina-Leonor Olivé-Marti, Nadine Hochrainer, Roland Hellinger, Johannes Koehbach, Jonathan F Fay, Mohammad Homaidur Rahman, Lamees Hegazy, Timothy W Craven, Balazs R Varga, Gaurav Bhardwaj, Kevin Appourchaux, Susruta Majumdar, Markus Muttenthaler, Parisa Hosseinzadeh, David J Craik, Mariana Spetea, Tao Che, Julien S Baker, Christian W Gruber
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nature communications 14 (1) (2023)
Benedikt Geier, Esther Gil-Mansilla, Zita Liutkevičiūtė, Roland Hellinger, Jozef Vanden Broeck, Janina Oetjen, Manuel Liebeke, Christian W Gruber
Multiplexed neuropeptide mapping in ant brains integrating microtomography and three-dimensional mass spectrometry imaging. PNAS nexus 2 (5) (2023)
Edin Muratspahić, Despoina Aslanoglou, Andrew M White, Claudia Draxler, Xaver Kozisek, Zara Farooq, David J Craik, Peter J McCormick, Thomas Durek, Christian W Gruber
Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds. ACS pharmacology & translational science 6 (10) (2023)
Edin Muratspahić, Andrew M White, Cosmin I Ciotu, Nadine Hochrainer, Nataša Tomašević, Johannes Koehbach, Richard James Lewis, Mariana Spetea, Michael J M Fischer, David J Craik, Christian W Gruber
Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples. Journal of medicinal chemistry (2023)
Bernhard Retzl, Amy Marisa Zimmermann-Klemd, Moritz Winker, Sven Nicolay, Carsten Gründemann, Christian W Gruber
Exploring Immune Modulatory Effects of Cyclotide-Enriched Viola tricolor Preparations. Planta medica (2023)
Zoltan Dekan, Thomas Kremsmayr, Peter Keov, Mathilde Godin, Ngari Teakle, Leopold Dürrauer, Huang Xiang, Dalia Gharib, Christian Bergmayr, Roland Hellinger, Marina Gay, Marta Vilaseca, Dennis Kurzbach, Fernando Albericio, Paul F Alewood, Christian W Gruber, Markus Muttenthaler
Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin. Chemical science 12 (11) (2021)
Roland Hellinger, Edin Muratspahić, Seema Devi, Johannes Koehbach, Mina Vasileva, Peta J Harvey, David J Craik, Carsten Gründemann, Christian W Gruber
Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides. ACS chemical biology 16 (11) (2021)
Edin Muratspahić, Nataša Tomašević, Shahrooz Nasrollahi-Shirazi, Jasmin Gattringer, Fabiola Susanna Emser, Michael Freissmuth, Christian W Gruber
Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling. Journal of natural products 84 (8) (2021)
Edin Muratspahić, Nataša Tomašević, Johannes Koehbach, Leopold Duerrauer, Seid Hadžić, Joel Castro, Gudrun Schober, Spyridon Sideromenos, Richard J Clark, Stuart M Brierley, David J Craik, Christian W Gruber
Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. Journal of medicinal chemistry 64 (13) (2021)
Meri Emili F Pinto, Lai Yue Chan, Johannes Koehbach, Seema Devi, Carsten Gründemann, Christian W Gruber, Mario Gomes, Vanderlan da Silva Bolzani, Eduardo Maffud Cilli, David J Craik
Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes. Journal of natural products 84 (1) (2021)
Mariateresa Giustiniano, Christian W Gruber, Caitlin N Kent, Paul C Trippier
Back to the Medicinal Chemistry Future. Journal of medicinal chemistry 64 (21) (2021)
Behzad Shahin-Kaleybar, Ali Niazi, Alireza Afsharifar, Ghorbanali Nematzadeh, Reza Yousefi, Bernhard Retzl, Roland Hellinger, Edin Muratspahić, Christian W Gruber
Isolation of Cysteine-Rich Peptides from Citrullus colocynthis. Biomolecules 10 (9) (2020)
Bernhard Retzl, Roland Hellinger, Edin Muratspahić, Meri Emili Ferreira Pinto, Vanderlan da Silva Bolzani, Christian W Gruber
Discovery of a Beetroot Protease Inhibitor to Identify and Classify Plant-Derived Cystine Knot Peptides. Journal of natural products 83 (11) (2020)
Edin Muratspahić, Johannes Koehbach, Christian W Gruber, David J Craik
Harnessing cyclotides to design and develop novel peptide GPCR ligands. RSC chemical biology 1 (4) (2020)
Peter Keov, Zita Liutkevičiūtė, Roland Hellinger, Richard J Clark, Christian W Gruber
Discovery of peptide probes to modulate oxytocin-type receptors of insects. Scientific reports 8 (1) (2018)
Markus Muttenthaler, Åsa Andersson, Irina Vetter, Rohit Menon, Marta Busnelli, Lotten Ragnarsson, Christian Bergmayr, Sarah Arrowsmith, Jennifer R Deuis, Han Sheng Chiu, Nathan J Palpant, Margaret O'Brien, Terry J Smith, Susan Wray, Inga D Neumann, Christian W Gruber, Richard James Lewis, Paul F Alewood
Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science signaling 10 (508) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christian W Gruber