Richard H Moriggl (R Moriggl, Richard Moriggl)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 48

Top Venues

Nature immunology

Leukemia

Blood

Nature communications

Veterinary University Vienna

Institute of Experimental Cancer Research (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Veterinary University Vienna Feb 01 2014

Austria

Prof.

Education History

Institute of Experimental Cancer Research Sep 01 1994 - Sep 01 1997

Germany

PHD :: Department of Biology, University of Freiburg

Friedrich Miescher Institute Sep 01 1993 - Sep 01 1994

Switzerland

PHD

CNRS Délégation Alsace Sep 01 1992 - Sep 01 1993

France

MSC :: Institute of Cell and Molecular Biology

Publications

Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology 25 (5) (2024)
Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Randhawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof Albert Bertram, Richard H Moriggl, Thomas Rülicke, Charles G Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia. Blood (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology 25 (5) (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology 25 (5) (2024)
Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A Betram, Richard H Moriggl, Thomas Rülicke, Charles G Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia. Blood 143 (24) (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology 25 (5) (2024)
Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A Betram, Richard H Moriggl, Thomas Rülicke, Charles G Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia. Blood 143 (24) (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Randhawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof Albert Bertram, Richard H Moriggl, Thomas Rülicke, Charles G Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia. Blood (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology 25 (5) (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna M Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A Neubauer, Richard H Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature immunology (2024)
Jana von Jan, Sanna Timonen, Till Braun, Qu Jiang, Aleksandr Ianevski, Yayi Peng, Kathleen McConnell, Paola Sindaco, Tony Andreas Müller, Sabine Pützer, Hanna Klepzig, Dennis Jungherz, Annika Dechow, Linus Wahnschaffe, Anil K Giri, Matti Kankainen, Heikki Kuusanmäki, Heidi A Neubauer, Richard H Moriggl, Paolo Mazzeo, Nicole Schmidt, Raphael Koch, Michael J Hallek, Amel Chebel, David Armisen, Laurent Genestier, Emmanuel Bachy, Anjali Mishra, Alexandra Schrader, Tero Aittokallio, Mohamed El Missiry, Marco Herling
Optimizing Drug Combinations for T-PLL: Restoring DNA Damage and P53-Mediated Apoptotic Responses. Blood (2024)
Jessica Ebner, Johannes Schmoellerl, Martin Piontek, Gabriele Manhart, Selina Troester, Bing Z Carter, Heidi A Neubauer, Richard H Moriggl, Gergely Szakács, Johannes Zuber, Thomas Köcher, Michael Andreeff, Wolfgang R Sperr, Peter Valent, Florian Grebien
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia. Nature communications 14 (1) (2023)
Diaaeldin I Abdallah, Elvin Dominic de Araujo, Naman H Patel, Lina S Hasan, Richard H Moriggl, Oliver Holger Krämer, Patrick Thomas Gunning
Medicinal chemistry advances in targeting class I histone deacetylases. Exploration of targeted anti-tumor therapy 4 (4) (2023)
Helena Sorger, Saptaswa Dey, Pablo Augusto Vieyra-Garcia, Daniel Pölöske, Andrea R Teufelberger, Elvin Dominic de Araujo, Abootaleb Sedighi, Ricarda Graf, Benjamin Spiegl, Isaac Lazzeri, Till Braun, Ines Garces de Los Fayos Alonso, Michaela Schlederer, Gerald Timelthaler, Petra Kodajova, Christine Pirker, Marta Surbek, Michael Machtinger, Thomas Graier, Isabella Perchthaler, Yi Pan, Regina Fink-Puches, Lorenzo Cerroni, Jennifer Ober, Moritz Otte, Jana D Albrecht, Gary Tin, Ayah Abdeldayem, Pimyupa Manaswiyoungkul, Olasunkanmi O Olaoye, Martin L Metzelder, Anna Orlova, Walter Berger, Marion Wobser, Jan P Nicolay, Fiona André, Van Anh Nguyen, Heidi A Neubauer, Roman Fleck, Olaf Merkel, Marco Herling, Ellen Heitzer, Patrick Thomas Gunning, Lukas Kenner, Richard H Moriggl, Peter Wolf
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma. EMBO molecular medicine 14 (12) (2022)
Harsimran Kaur Garcha, Nabanita Nawar, Helena Sorger, Fettah Erdogan, Myint Myat Khine Aung, Abootaleb Sedighi, Pimyupa Manaswiyoungkul, Hyuk-Soo Seo, Susann Schönefeldt, Daniel Pölöske, Sirano Dhe-Paganon, Heidi A Neubauer, Mohamed El Missiry, Marco Herling, Elvin D de Araujo, Richard H Moriggl, Patrick T Gunning
High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma. Pharmaceuticals (Basel, Switzerland) 15 (11) (2022)
Sebastian Kollmann, Reinhard Grausenburger, Thorsten Klampfl, Michaela Prchal-Murphy, Klavdija Bastl, Hanja Pisa, Vanessa M Knab, Tania Brandstoetter, Eszter Doma, Wolfgang R Sperr, Sabine Lagger, Matthias Farlik, Richard H Moriggl, Peter Valent, Florian Halbritter, Karoline Kollmann, Gerwin Heller, Barbara Maurer, Veronika Sexl
A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells. Blood 138 (23) (2022)
Marianna Beghini, Theresia Wagner, Andreea Corina Luca, Matthäus Metz, Doris Kaltenecker, Katrin Spirk, Martina Theresa Hackl, Johannes Haybaeck, Richard H Moriggl, Alexandra Kautzky-Willer, Thomas Scherer, Clemens Fürnsinn
Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice. PloS one 16 (11) (2021)
Javier Bregante, Anna Schönbichler, Daniel Pölöske, Lina Degenfeld-Schonburg, Garazi Monzó Contreras, Emir Hadzijusufovic, Elvin D de Araujo, Peter Valent, Richard H Moriggl, Anna Orlova
Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3 -ITD + Acute Myeloid Leukemia. Cancers 13 (24) (2021)
Susann Schönefeldt, Tamara Wais, Marco Herling, Mohamed El Missiry, Vasileios Bekiaris, Richard H Moriggl, Heidi A Neubauer
The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma. Cancers 13 (24) (2021)
Daehong Kim, Giljun Park, Jani Huuhtanen, Bishwa R Ghimire, Hanna Rajala, Richard H Moriggl, Wing C Chan, Matti Kankainen, Mikko Myllymäki, Mohamed El Missiry
STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation. Leukemia 35 (12) (2021)
Matthias Kieslinger, Alexander Swoboda, Nina Kramer, Patricia Freund, Barbara Pratscher, Heidi A Neubauer, Ralf Steinborn, Birgitt Wolfesberger, Andrea Fuchs-Baumgartinger, Richard H Moriggl, Iwan Anton Burgener
A Recurrent STAT5BN642H Driver Mutation in Feline Alimentary T Cell Lymphoma. Cancers 13 (20) (2021)
Kristina Breitenecker, Monika Homolya, Andreea C Luca, Veronika Lang, Christoph Trenk, Georg Petroczi, Julian Mohrherr, Jaqueline Horvath, Stefan Moritsch, Lisa Haas, Margarita Kurnaeva, Robert Eferl, Dagmar Stoiber, Richard H Moriggl, Martin Bilban, Anna C Obenauf, Christiane Ferran, Balázs Dome, Viktoria Laszlo, Balázs Győrffy, Katalin Dezso, Judit Moldvay, Emilio Casanova, Herwig P Moll
Down-regulation of A20 promotes immune escape of lung adenocarcinomas. Science translational medicine 13 (601) (2021)
Miriam Pons, Yanira Zeyn, Stella Zahn, Nisintha Mahendrarajah, Brent D G Page, Patrick T Gunning, Richard H Moriggl, Walburgis Brenner, Falk Butter, Oliver Holger Krämer
Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis Inhibition. Cancers 13 (14) (2021)
Alexander Swoboda, Robert Soukup, Oliver Eckel, Katharina Kinslechner, Bettina Wingelhofer, David Schörghofer, Christina Sternberg, Ha T T Pham, Maria Vallianou, Jaqueline Horvath, Dagmar Stoiber, Lukas Kenner, Lionel Larue, Valeria Poli, Friedrich Beermann, Takashi Yokota, Stefan Kubicek, Thomas Krausgruber, André Figueiredo Rendeiro, Christoph Bock, Rainer Zenz, Boris Kovacic, Fritz Aberger, Markus Hengstschläger, Peter Petzelbauer, Mario Mikula, Richard H Moriggl
STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway. Oncogene 40 (6) (2020)
Petra Aigner, Tatsuaki Mizutani, Jaqueline Horvath, Thomas Eder, Stefan Heber, Karin Lind, Valentin Just, Herwig P Moll, Assa Yeroslaviz, Michael J M Fischer, Lukas Kenner, Balázs Győrffy, Heinz Sill, Florian Grebien, Richard H Moriggl, Emilio Casanova, Dagmar Stoiber
STAT3β is a tumor suppressor in acute myeloid leukemia. Blood advances 3 (13) (2020)
Elvin D de Araujo, György M Keserű, Patrick T Gunning, Richard H Moriggl
Targeting STAT3 and STAT5 in Cancer. Cancers 12 (8) (2020)
Elvin Dominic de Araujo, Fettah Erdogan, Heidi A Neubauer, Deniz Meneksedag-Erol, Pimyupa Manaswiyoungkul, Mohammad S Eram, Hyuk-Soo Seo, Abdul K Qadree, Johan Israelian, Anna Orlova, Tobias Suske, Ha Thi Thanh Pham, Auke Boersma, Simone Tangermann, Lukas Kenner, Thomas Rülicke, Aiping Dong, Manimekalai Ravichandran, Peter J Brown, Gerald F Audette, Sarah Rauscher, Sirano Dhe-Paganon, Richard H Moriggl, Patrick T Gunning
Structural and functional consequences of the STAT5BN642H driver mutation. Nature communications 10 (1) (2019)
Klara Klein, Agnieszka Witalisz-Siepracka, Barbara Maurer, Daniela Prinz, Gerwin Heller, Nicoletta Leidenfrost, Michaela Prchal-Murphy, Tobias Suske, Richard H Moriggl, Veronika Sexl
STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia. Leukemia 33 (9) (2019)
Manuel Rauth, Patricia Freund, Anna Orlova, Stefan Grünert, Nikola Tasic, Xiaonan Han, Hai-Bin Ruan, Heidi A Neubauer, Richard H Moriggl
Cell Metabolism Control Through O-GlcNAcylation of STAT5: A Full or Empty Fuel Tank Makes a Big Difference for Cancer Cell Growth and Survival. International journal of molecular sciences 20 (5) (2019)
Herwig P Moll, Klemens Pranz, Monica Musteanu, Beatrice Grabner, Natascha Hruschka, Julian Mohrherr, Petra Aigner, Patricia Stiedl, Luka Brcic, Viktoria Laszlo, Daniel Schramek, Richard H Moriggl, Robert Eferl, Judit Moldvay, Katalin Dezso, Pedro P López-Casas, Dagmar Stoiber, Manuel Hidalgo, Josef M Penninger, Maria Sibilia, Balázs Győrffy, Mariano Barbacid, Balázs Dome, Helmut H Popper, Emilio Casanova
Afatinib restrains K-RAS-driven lung tumorigenesis. Science translational medicine 10 (446) (2019)
Bettina Wingelhofer, Barbara Maurer, Elizabeth C Heyes, Abbarna A Cumaraswamy, Angelika Berger-Becvar, Elvin D de Araujo, Anna Orlova, Patricia Freund, Frank Ruge, Jisung Park, Gary Tin, Siawash Ahmar, Charles-Hugues Lardeau, Irina Sadovnik, Dávid Bajusz, György Miklós Keserű, Florian Grebien, Stefan Kubicek, Peter Valent, Patrick T Gunning, Richard H Moriggl
Pharmacologic inhibition of STAT5 in acute myeloid leukemia. Leukemia 32 (5) (2018)
Bettina Wingelhofer, Heidi A Neubauer, Peter Valent, Xiaonan Han, Stefan N Constantinescu, Patrick T Gunning, Mathias Müller, Richard H Moriggl
Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer. Leukemia 32 (8) (2018)
A Schrader, G Crispatzu, S Oberbeck, P Mayer, S Pützer, J von Jan, E Vasyutina, K Warner, N Weit, N Pflug, T Braun, Emma I Andersson, B Yadav, A Riabinska, B Maurer, M S Ventura Ferreira, F Beier, J Altmüller, M Lanasa, C D Herling, T Haferlach, S Stilgenbauer, G Hopfinger, Martin Peifer, T H Brümmendorf, P Nürnberg, K S J Elenitoba-Johnson, S Zha, M Hallek, Richard H Moriggl, H C Reinhardt, Marc-Henri Stern, S Mustjoki, S Newrzela, P Frommolt, M Herling
Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL. Nature communications 9 (1) (2018)
Nicole Prutsch, Elisabeth Gurnhofer, Tobias Suske, Huan Chang Liang, Michaela Schlederer, Simone Roos, Lawren C Wu, Ingrid Simonitsch-Klupp, Andrea Alvarez-Hernandez, Christoph Kornauth, Dario A Leone, Jasmin Svinka, Robert Eferl, Tanja Limberger, Astrid Aufinger, Nitesh Shirsath, Peter Wolf, Thomas Hielscher, Christina Sternberg, Fritz Aberger, Johannes Schmoellerl, Dagmar Stoiber, Birgit Strobl, Ulrich Jäger, Philipp B Staber, Florian Grebien, Richard H Moriggl, Mathias Müller, Giorgio G Inghirami, Takaomi Sanda, A Thomas Look, Suzanne D Turner, Lukas Kenner, Olaf Merkel
Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma. Leukemia 33 (3) (2018)
B Peter, S Bibi, G Eisenwort, B Wingelhofer, D Berger, G Stefanzl, K Blatt, H Herrmann, Emir Hadzijusufovic, G Hoermann, T Hoffmann, J Schwaab, M Jawhar, M Willmann, W R Sperr, Johannes Zuber, K Sotlar, H-P Horny, Richard H Moriggl, A Reiter, M Arock, P Valent
Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells. Leukemia 32 (4) (2017)
P Freund, M A Kerenyi, M Hager, T Wagner, B Wingelhofer, H T T Pham, M Elabd, X Han, P Valent, F Gouilleux, V Sexl, O H Krämer, B Groner, Richard H Moriggl
O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies. Leukemia 31 (10) (2017)
N Kramer, J Schmöllerl, C Unger, H Nivarthi, A Rudisch, D Unterleuthner, M Scherzer, A Riedl, M Artaker, I Crncec, D Lenhardt, T Schwarz, B Prieler, X Han, M Hengstschläger, J Schüler, R Eferl, Richard H Moriggl, W Sommergruber, Helmut Dolznig
Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression. Oncogene 36 (39) (2017)
Karin Eigner, Yüksel Filik, Florian Mark, Birgit Schütz, Günter Klambauer, Richard H Moriggl, Markus Hengstschläger, Herbert Stangl, Mario Mikula, Clemens Röhrl
The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone. Scientific reports 7 (1) (2017)
S Ghanem, K Friedbichler, C Boudot, J Bourgeais, V Gouilleux-Gruart, A Régnier, O Herault, Richard H Moriggl, F Gouilleux
STAT5A/5B-specific expansion and transformation of hematopoietic stem cells. Blood cancer journal 7 (1) (2017)
Margit Rosner, Ha Thi Thanh Pham, Richard H Moriggl, Markus Hengstschläger
Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1. Nature communications 8 (1) (2017)
A K Jayavelu, J P Müller, R Bauer, S-A Böhmer, J Lässig, S Cerny-Reiterer, W R Sperr, P Valent, B Maurer, Richard H Moriggl, K Schröder, A M Shah, M Fischer, S Scholl, J Barth, T Oellerich, T Berg, H Serve, S Frey, T Fischer, F H Heidel, F-D Böhmer
NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells. Leukemia 30 (2) (2015)
Beatrice Grabner, Daniel Schramek, Kristina M Mueller, Herwig P Moll, Jasmin Svinka, Thomas Hoffmann, Eva Bauer, Leander Blaas, Natascha Hruschka, Katalin Zboray, Patricia Stiedl, Harini Nivarthi, Edith Bogner, Wolfgang Gruber, Thomas Mohr, Ralf Harun Zwick, Lukas Kenner, Valeria Poli, Fritz Aberger, Dagmar Stoiber, Gerda Egger, Harald Esterbauer, Johannes Zuber, Richard H Moriggl, Robert Eferl, Balázs Győrffy, Josef M Penninger, Helmut Popper, Emilio Casanova
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nature communications 6 (2015)

Richard H Moriggl.css-eqlu8i{font-size:small;padding-left:4px;} (R Moriggl, Richard Moriggl)

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Richard H Moriggl (R Moriggl, Richard Moriggl)