Susana Minguet

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Nature immunology

Science advances

eLife

Nature communications

Institute for Biology III, Faculty of Biology, University of Freiburg, Germany

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute for Biology III, Faculty of Biology, University of Freiburg, Germany Dec 01 2017

Germany

Group leader :: Department of Immunology

Publications

Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Anna-Maria Schaffer, Gina Jasmin Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Babrak, Laurenz Alexander Herr, Mari Carmen Romero-Mulero, Nina Cabezas-Wallscheid, Marta Rizzi, Enkelejda Miho, Wolfgang W A Schamel, Susana Minguet
Kidins220 regulates the development of B cells bearing the λ light chain. eLife 13 (2024)
Anna-Maria Schaffer, Gina Jasmin Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Babrak, Laurenz Alexander Herr, Mari Carmen Romero-Mulero, Nina Cabezas-Wallscheid, Marta Rizzi, Enkelejda Miho, Wolfgang W A Schamel, Susana Minguet
Kidins220 regulates the development of B cells bearing the λ light chain. eLife 13 (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Vanessa Mühlgrabner, Timo Peters, Rubí M-H Velasco Cárdenas, Benjamin Salzer, Janett Göhring, Angelika Plach, Maria Höhrhan, Iago Doel Perez, Vasco Dos Reis Gonçalves, Jesús Siller Farfán, Manfred Lehner, Hannes Stockinger, Wolfgang W A Schamel, Kilian Schober, Dirk H Busch, Michael Hudecek, Omer Dushek, Susana Minguet, René Platzer, Johannes B Huppa
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation. Science advances 10 (36) (2024)
Vanessa Mühlgrabner, Timo Peters, Rubí M-H Velasco Cárdenas, Benjamin Salzer, Janett Göhring, Angelika Plach, Maria Höhrhan, Iago Doel Perez, Vasco Dos Reis Gonçalves, Jesús Siller Farfán, Manfred Lehner, Hannes Stockinger, Wolfgang W A Schamel, Kilian Schober, Dirk H Busch, Michael Hudecek, Omer Dushek, Susana Minguet, René Platzer, Johannes B Huppa
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation. Science advances 10 (36) (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology (2024)
Anna-Maria Schaffer, Gina Jasmin Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Babrak, Laurenz Alexander Herr, Mari Carmen Romero-Mulero, Nina Cabezas-Wallscheid, Marta Rizzi, Enkelejda Miho, Wolfgang W A Schamel, Susana Minguet
Kidins220 regulates the development of B cells bearing the λ light chain. eLife 13 (2024)
Laurenz Alexander Herr, Gina J Fiala, Sagar, Anna-Maria Schaffer, Jonas F Hummel, Marina Zintchenko, Katrin Raute, Rubí M-H Velasco Cárdenas, Beate Heizmann, Karolina Ebert, Kerstin Fehrenbach, Iga Janowska, Susan Chan, Yakup Tanriver, Susana Minguet, Wolfgang W A Schamel
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Science advances 10 (11) (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Anna-Maria Schaffer, Gina Jasmin Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Babrak, Laurenz Alexander Herr, Mari Carmen Romero-Mulero, Nina Cabezas-Wallscheid, Marta Rizzi, Enkelejda Miho, Wolfgang W A Schamel, Susana Minguet
Kidins220 regulates the development of B cells bearing the λ light chain. eLife 13 (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Nital Sumaria, Gina J Fiala, Daniel Inácio, Marta Curado-Avelar, Ana Cachucho, Rúben Pinheiro, Robert Wiesheu, Shunsuke Kimura, Lucien Courtois, Birte Blankenhaus, Julie Darrigues, Tobias Suske, Afonso R M Almeida, Susana Minguet, Vahid Asnafi, Ludovic Lhermitte, Charles G Mullighan, Seth B Coffelt, Richard H Moriggl, João T Barata, Daniel J Pennington, Bruno Silva-Santos
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms. Nature immunology 25 (7) (2024)
Laurenz Alexander Herr, Gina J Fiala, Sagar, Anna-Maria Schaffer, Jonas F Hummel, Marina Zintchenko, Katrin Raute, Rubí M-H Velasco Cárdenas, Beate Heizmann, Karolina Ebert, Kerstin Fehrenbach, Iga Janowska, Susan Chan, Yakup Tanriver, Susana Minguet, Wolfgang W A Schamel
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Science advances 10 (11) (2024)
Laurenz Alexander Herr, Gina J Fiala, Sagar, Anna-Maria Schaffer, Jonas F Hummel, Marina Zintchenko, Katrin Raute, Rubí M-H Velasco Cárdenas, Beate Heizmann, Karolina Ebert, Kerstin Fehrenbach, Iga Janowska, Susan Chan, Yakup Tanriver, Susana Minguet, Wolfgang W A Schamel
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Science advances 10 (11) (2024)
Laurenz Alexander Herr, Gina J Fiala, Sagar, Anna-Maria Schaffer, Jonas F Hummel, Marina Zintchenko, Katrin Raute, Rubí M-H Velasco Cárdenas, Beate Heizmann, Karolina Ebert, Kerstin Fehrenbach, Iga Janowska, Susan Chan, Yakup Tanriver, Susana Minguet, Wolfgang W A Schamel
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Science advances 10 (11) (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Patricia Hernández-López, Eline van Diest, Peter Brazda, Sabine Heijhuurs, Angelo Meringa, Lauren Hoorens van Heyningen, Caterina Riillo, Caroline Schwenzel, Marina Zintchenko, Inez Johanna, Mara J T Nicolasen, Astrid Cleven, Thomas A Kluiver, Rosemary Millen, Jiali Zheng, Froso Karaiskaki, Trudy Straetemans, Hans Clevers, Remco de Bree, Hendrik G Stunnenberg, Weng Chuan Peng, Jeanine Roodhart, Susana Minguet, Zsolt Sebestyén, Dennis X Beringer, Jürgen H E Kuball
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells. Nature immunology (2023)
Marlene Langenbach, Sophie Giesler, Stefan Richtsfeld, Sara Costa-Pereira, Lukas Rindlisbacher, Tobias Wertheimer, Lukas M Braun, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Nadine M Woessner, Hans D Menssen, Sanaz Taromi, Justus Duyster, Melanie Börries, Tilman Brummer, Bruce R Blazar, Susana Minguet, Patrick Turko, Mitchell Paul Levesque, Burkhard Becher, Robert Zeiser
MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production. Molecular cancer research : MCR (2023)
Victor G Lui, Manfred Hoenig, Berenice Cabrera-Martinez, Ryan M Baxter, Josselyn E Garcia-Perez, Olivia Bailey, Atanu Acharya, Karl Lundquist, Jesusa Capera, Paul Matusewicz, Frederike A Hartl, Marco D'Abramo, Josephine Alba, Eva-Maria Jacobsen, Doris Niewolik, Myriam Lorenz, Ulrich Pannicke, Ansgar S Schulz, Klaus-Michael Debatin, Wolfgang W A Schamel, Susana Minguet, James C Gumbart, Michael L Dustin, John C Cambier, Klaus Schwarz, Elena W Y Hsieh
A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation. The Journal of experimental medicine 221 (1) (2023)
Katrin Raute, Juliane Strietz, Maria Alejandra Parigiani, Geoffroy Andrieux, Oliver S Thomas, Klaus M Kistner, Marina Zintchenko, Peter Aichele, Maike Hofmann, Houjiang Zhou, Wilfried Weber, Melanie Börries, Mahima Swamy, Jochen Maurer, Susana Minguet
Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands. Cancer immunology research (2023)
Rubí M-H Velasco Cárdenas, Simon M Brandl, Ana Valeria Meléndez, Alexandra Emilia Schlaak, Annabelle Buschky, Timo Peters, Fabian Beier, Bryan Serrels, Sanaz Taromi, Katrin Raute, Simon Hauri, Matthias Gstaiger, Silke Lassmann, Johannes B Huppa, Melanie Börries, Geoffroy Andrieux, Bertram Bengsch, Wolfgang W A Schamel, Susana Minguet
Harnessing CD3 diversity to optimize CAR T cells. Nature immunology (2023)
Annika Schultz, Marvin Schnurra, Ali El-Bizri, Nadine M Woessner, Sara Hartmann, Roland Hartig, Susana Minguet, Burkhart Schraven, Luca Simeoni
A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR Signaling. Cells 11 (17) (2022)
Tamina Rückert, Geoffroy Andrieux, Melanie Börries, Kathrin Hanke-Müller, Nadine M Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M Braun, Eileen Haring, Sandra Kissel, Benjamin A Siranosian, Ami Siddharth Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin Anderschou Holbech Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Stickel
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Science translational medicine 14 (676) (2022)
Ana Valeria Meléndez, Rubí M-H Velasco Cárdenas, Simon Lagies, Juliane Strietz, Lina Siukstaite, Oliver S Thomas, Jana Tomisch, Wilfried Weber, Bernd Kammerer, Winfried Römer, Susana Minguet
Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells. Cellular and molecular life sciences : CMLS 79 (10) (2022)
Tamina Rückert, Geoffroy Andrieux, Melanie Börries, Kathrin Hanke-Müller, Nadine M Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M Braun, Eileen Haring, Sandra Kissel, Benjamin A Siranosian, Ami Siddharth Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin Anderschou Holbech Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Stickel
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Science translational medicine 14 (676) (2022)
Tamina Rückert, Geoffroy Andrieux, Melanie Börries, Kathrin Hanke-Müller, Nadine M Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M Braun, Eileen Haring, Sandra Kissel, Benjamin A Siranosian, Ami Siddharth Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin Anderschou Holbech Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Stickel
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Science translational medicine 14 (676) (2022)
Florian Emmerich, Stefan Zschiedrich, Christine Reichenbach-Braun, Caner Süsal, Susana Minguet, Marie-Christin Pauly, Maximilian Seidl
Low Pre-Transplant Caveolin-1 Serum Concentrations Are Associated with Acute Cellular Tubulointerstitial Rejection in Kidney Transplantation. Molecules (Basel, Switzerland) 26 (9) (2021)
Frederike A Hartl, Jatuporn Ngoenkam, Esmeralda Beck-Garcia, Liz Cerqueira, Piyamaporn Wipa, Pussadee Paensuwan, Prapat Suriyaphol, Pankaj Mishra, Burkhart Schraven, Stefan Günther, Sutatip Pongcharoen, Wolfgang W A Schamel, Susana Minguet
Cooperative Interaction of Nck and Lck Orchestrates Optimal TCR Signaling. Cells 10 (4) (2021)
Frederike A Hartl, Esmeralda Beck-Garcìa, Nadine M Woessner, Lea J Flachsmann, Rubí M-H Velasco Cárdenas, Simon M Brandl, Sanaz Taromi, Gina J Fiala, Anna Morath, Pankaj Mishra, Omid Sascha Yousefi, Julia Zimmermann, Nico Hoefflin, Maja Köhn, Birgitta M Wöhrl, Robert Zeiser, Kristian Schweimer, Stefan Günther, Wolfgang W A Schamel, Susana Minguet
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function. Nature immunology 21 (8) (2020)
Frederike A Hartl, Esmeralda Beck-Garcìa, Nadine M Woessner, Lea J Flachsmann, Rubí M-H Velasco Cárdenas, Simon M Brandl, Sanaz Taromi, Gina J Fiala, Anna Morath, Pankaj Mishra, Omid Sascha Yousefi, Julia Zimmermann, Nico Hoefflin, Maja Köhn, Birgitta M Wöhrl, Robert Zeiser, Kristian Schweimer, Stefan Günther, Wolfgang W A Schamel, Susana Minguet
Author Correction: Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function. Nature immunology (2020)
Gina J Fiala, Anna-Maria Schaffer, Katja Merches, Anna Morath, Jeremy Swann, Laurenz Alexander Herr, Miriam Hils, Charlotte Esser, Susana Minguet, Wolfgang W A Schamel
Proximal Lck Promoter-Driven Cre Function Is Limited in Neonatal and Ineffective in Adult γδ T Cell Development. Journal of immunology (Baltimore, Md. : 1950) 203 (2) (2019)
Alessandro Prestipino, Alica J Emhardt, Konrad Aumann, David O'Sullivan, Sivahari P Gorantla, Sandra Duquesne, Wolfgang Melchinger, Lukas M Braun, Slavica Vuckovic, Melanie Boerries, Hauke Busch, Sebastian Halbach, Sandra Pennisi, Teresa Poggio, Petya Apostolova, Pia Veratti, Michael Hettich, Gabriele Niedermann, Mark D Bartholomä, Khalid Shoumariyeh, Jonas Samuel Jutzi, Julius Wehrle, Christine Dierks, Heiko Becker, Annette Schmitt-Graeff, Marie Follo, Dietmar Pfeifer, Jan C Rohr, Sebastian Fuchs, Stephan Ehl, Frederike A Hartl, Susana Minguet, Christoph Cornelius Miething, Florian H Heidel, Nicolaus M Kröger, Ioanna Triviai, Tilman Brummer, Jürgen Finke, Anna L Illert, Eliana Ruggiero, Chiara Bonini, Justus Duyster, Heike Luise Pahl, Steven W Lane, Geoffrey R Hill, Bruce R Blazar, Nikolas von Bubnoff, Erika L Pearce, Robert Zeiser
Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science translational medicine 10 (429) (2019)
Julia Baaske, Patrick Gonschorek, Raphael Engesser, Alazne Dominguez-Monedero, Katrin Raute, Patrick Fischbach, Konrad Müller, Elise Cachat, Wolfgang W A Schamel, Susana Minguet, Jamie A Davies, Jens Timmer, Wilfried Weber, Matias D Zurbriggen
Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells. Scientific reports 8 (1) (2018)
Susana Minguet, Kathrin Kläsener, Anna-Maria Schaffer, Gina J Fiala, Teresa Osteso-Ibánez, Katrin Raute, Inmaculada Navarro-Lérida, Frederike A Hartl, Maximilian Seidl, Michael Reth, Miguel A Del Pozo
Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance. Nature immunology 18 (10) (2017)

Susana Minguet.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Susana Minguet