Matthieu Schapira

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 56

Top Topics

Cancer Stem Cells

Histone Deacetylase

Top Venues

Journal of medicinal chemistry

Nature chemical biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Darren Yong, Shabbir Ahmad, Mark F Mabanglo, Levon Halabelian, Matthieu Schapira, Suzanne Ackloo, Sumera Perveen, Pegah Ghiabi, Masoud Vedadi
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions. Biochemistry 63 (10) (2024)
Matthieu Schapira, Levon Halabelian, Cheryl H Arrowsmith, Rachel J Harding
Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design. Nature chemical biology (2024)
Corentin Bedart, Grace Shimokura, Frederick G West, Tabitha E Wood, Robert A Batey, John J Irwin, Matthieu Schapira
The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening. Scientific data 11 (1) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology 20 (9) (2024)
Corentin Bedart, Grace Shimokura, Frederick G West, Tabitha E Wood, Robert A Batey, John J Irwin, Matthieu Schapira
The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening. Scientific data 11 (1) (2024)
Merveille Eguida, Guillaume Bret, François Sindt, Fengling Li, Irene Chau, Suzanne Ackloo, Cheryl Arrowsmith, Albina Bolotokova, Pegah Ghiabi, Elisa Gibson, Levon Halabelian, Scott Houliston, Rachel J Harding, Ashley Hutchinson, Peter Loppnau, Sumera Perveen, Almagul Seitova, Hong Zeng, Matthieu Schapira, Didier Rognan
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2. Journal of chemical information and modeling (2024)
Corentin Bedart, Grace Shimokura, Frederick G West, Tabitha E Wood, Robert A Batey, John J Irwin, Matthieu Schapira
The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening. Scientific data 11 (1) (2024)
Corentin Bedart, Grace Shimokura, Frederick G West, Tabitha E Wood, Robert A Batey, John J Irwin, Matthieu Schapira
The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening. Scientific data 11 (1) (2024)
Evianne Rovers, Matthieu Schapira
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction. Journal of chemical information and modeling (2024)
Matthieu Schapira, Levon Halabelian, Cheryl H Arrowsmith, Rachel J Harding
Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design. Nature chemical biology (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology 20 (9) (2024)
Matthieu Schapira, Levon Halabelian, Cheryl H Arrowsmith, Rachel J Harding
Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design. Nature chemical biology 20 (8) (2024)
Kristina Edfeldt, Aled Morgan Edwards, Ola Engkvist, Judith Günther, Matthew Hartley, David G Hulcoop, Andrew R Leach, Brian D Marsden, Amelie Tjaden, Leonie Misquitta, Susanne Müller, Dafydd R Owen, Kristof T Schütt, Nicholas Skelton, Andreas Steffen, Alexander Trospsha, Erik Vernet, Yanli Wang, James Wellnitz, Timothy M Willson, Djork-Arné Clevert, Benjamin Haibe-Kains, Lovisa Holmberg Schiavone, Matthieu Schapira
A data science roadmap for open science organizations engaged in early-stage drug discovery. Nature communications 15 (1) (2024)
Merveille Eguida, Guillaume Bret, François Sindt, Fengling Li, Irene Chau, Suzanne Ackloo, Cheryl Arrowsmith, Albina Bolotokova, Pegah Ghiabi, Elisa Gibson, Levon Halabelian, Scott Houliston, Rachel J Harding, Ashley Hutchinson, Peter Loppnau, Sumera Perveen, Almagul Seitova, Hong Zeng, Matthieu Schapira, Didier Rognan
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2. Journal of chemical information and modeling 64 (13) (2024)
Kristina Edfeldt, Aled Morgan Edwards, Ola Engkvist, Judith Günther, Matthew Hartley, David G Hulcoop, Andrew R Leach, Brian D Marsden, Amelie Tjaden, Leonie Misquitta, Susanne Müller, Dafydd R Owen, Kristof T Schütt, Nicholas Skelton, Andreas Steffen, Alexander Trospsha, Erik Vernet, Yanli Wang, James Wellnitz, Timothy M Willson, Djork-Arné Clevert, Benjamin Haibe-Kains, Lovisa Holmberg Schiavone, Matthieu Schapira
A data science roadmap for open science organizations engaged in early-stage drug discovery. Nature communications 15 (1) (2024)
Kristina Edfeldt, Aled Morgan Edwards, Ola Engkvist, Judith Günther, Matthew Hartley, David G Hulcoop, Andrew R Leach, Brian D Marsden, Amelie Tjaden, Leonie Misquitta, Susanne Müller, Dafydd R Owen, Kristof T Schütt, Nicholas Skelton, Andreas Steffen, Alexander Trospsha, Erik Vernet, Yanli Wang, James Wellnitz, Timothy M Willson, Djork-Arné Clevert, Benjamin Haibe-Kains, Lovisa Holmberg Schiavone, Matthieu Schapira
A data science roadmap for open science organizations engaged in early-stage drug discovery. Nature communications 15 (1) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology (2024)
Darren Yong, Shabbir Ahmad, Mark F Mabanglo, Levon Halabelian, Matthieu Schapira, Suzanne Ackloo, Sumera Perveen, Pegah Ghiabi, Masoud Vedadi
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions. Biochemistry (2024)
Darren Yong, Shabbir Ahmad, Mark F Mabanglo, Levon Halabelian, Matthieu Schapira, Suzanne Ackloo, Sumera Perveen, Pegah Ghiabi, Masoud Vedadi
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions. Biochemistry 63 (10) (2024)
Darren Yong, Shabbir Ahmad, Mark F Mabanglo, Levon Halabelian, Matthieu Schapira, Suzanne Ackloo, Sumera Perveen, Pegah Ghiabi, Masoud Vedadi
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions. Biochemistry 63 (10) (2024)
Darren Yong, Shabbir Ahmad, Mark F Mabanglo, Levon Halabelian, Matthieu Schapira, Suzanne Ackloo, Sumera Perveen, Pegah Ghiabi, Masoud Vedadi
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions. Biochemistry 63 (10) (2024)
Evianne Rovers, Matthieu Schapira
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction. Journal of chemical information and modeling 64 (15) (2024)
Suzanne Ackloo, Albert A Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex N Bullock, Ulrich A K Betz, Jark Böttcher, Peter J Brown, Menorca Chaturvedi, Alisa Crisp, Danette L Daniels, Jan Dreher, Kristina Edfeldt, Aled Morgan Edwards, Ursula Egner, Jon Elkins, Christian Fischer, Tine Glendorf, Steven Goldberg, Ingo V Hartung, Alexander Hillisch, Evert J Homan, Stefan Knapp, Markus Köster, Oliver Krämer, Josep Llaveria, Uta Lessel, Sven Lindemann, Lars Linderoth, Hisanori Matsui, Maurice Michel, Florian Montel, Anke Mueller-Fahrnow, Susanne Müller, Dafydd R Owen, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Wendy Sanderson, Cora Scholten, Matthieu Schapira, Sujata Sharma, Brock Shireman, Michael Sundström, Matthew H Todd, Claudia Tredup, Jennifer Venable, Timothy M Willson, Cheryl H Arrowsmith
Target 2035 - an update on private sector contributions. RSC medicinal chemistry 14 (6) (2023)
Suzanne Ackloo, Albert A Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex N Bullock, Ulrich A K Betz, Jark Böttcher, Peter J Brown, Menorca Chaturvedi, Alisa Crisp, Danette L Daniels, Jan Dreher, Kristina Edfeldt, Aled Morgan Edwards, Ursula Egner, Jon Elkins, Christian Fischer, Tine Glendorf, Steven Goldberg, Ingo V Hartung, Alexander Hillisch, Evert J Homan, Stefan Knapp, Markus Köster, Oliver Krämer, Josep Llaveria, Uta Lessel, Sven Lindemann, Lars Linderoth, Hisanori Matsui, Maurice Michel, Florian Montel, Anke Mueller-Fahrnow, Susanne Müller, Dafydd R Owen, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Wendy Sanderson, Cora Scholten, Matthieu Schapira, Sujata Sharma, Brock Shireman, Michael Sundström, Matthew H Todd, Claudia Tredup, Jennifer Venable, Timothy M Willson, Cheryl H Arrowsmith
Target 2035 - an update on private sector contributions. RSC medicinal chemistry 14 (6) (2023)
Mandeep K Mann, Esther Wolf, Madhushika Silva, Haejin Angela Kwak, Brian Wilson, Albina Bolotokova, Derek J Wilson, Rachel J Harding, Matthieu Schapira
Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle. ACS omega 9 (1) (2023)
AkshatKumar Nigam, Matthew F D Hurley, Fengling Li, Eva KonkoĬová, Martin Klíma, Jana Trylčová, Robert Pollice, Süleyman Selim Çınaroğlu, Roni Levin-Konigsberg, Jasemine Handjaya, Matthieu Schapira, Irene Chau, Sumera Perveen, Ho-Leung Ng, H Ümit Kaniskan, Yulin Han, Sukrit Singh, Christoph Gorgulla, Anshul Kundaje, Jian Jin, Vincent A Voelz, Jan Weber, Radim Nencka, Evzen Boura, Masoud Vedadi, Alán Aspuru-Guzik
Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors. bioRxiv : the preprint server for biology (2023)
Rachel J Harding, Ivan Franzoni, Mandeep K Mann, Magdalena M Szewczyk, Bijan Mirabi, Renato Ferreira de Freitas, Dominic D G Owens, Suzanne Ackloo, Alexej Scheremetjew, Kevin A Juarez-Ornelas, Randy Sanichar, Rachel J Baker, Christian Dank, Peter J Brown, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Matthieu Schapira, Mark Lautens, Cheryl H Arrowsmith
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. Journal of medicinal chemistry (2023)
Mandeep K Mann, Esther Wolf, Madhushika Silva, Haejin Angela Kwak, Brian Wilson, Albina Bolotokova, Derek J Wilson, Rachel J Harding, Matthieu Schapira
Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle. ACS omega 9 (1) (2023)
Serah W Kimani, Julie Owen, Stuart R Green, Fengling Li, Yanjun Li, Aiping Dong, Peter J Brown, Suzanne Ackloo, David Kuter, Cindy Yang, Miranda MacAskill, Stephen Scott MacKinnon, Cheryl H Arrowsmith, Matthieu Schapira, Vijay Shahani, Levon Halabelian
Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets. Journal of chemical information and modeling (2023)
Samir H Barghout, Mandeep K Mann, Ahmed M Aman, Yifan Yu, Matthew G Alteen, Aaron D Schimmer, Matthieu Schapira, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy
Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes. ACS chemical biology 17 (10) (2022)
Mandeep K Mann, Carlos A Zepeda-Velázquez, Héctor González-Álvarez, Aiping Dong, Taira Kiyota, Ahmed M Aman, Peter Loppnau, Yanjun Li, Brian Wilson, Cheryl H Arrowsmith, Rima Al-Awar, Rachel J Harding, Matthieu Schapira
Structure-Activity Relationship of USP5 Inhibitors. Journal of medicinal chemistry 64 (20) (2021)
Setayesh Yazdani, Nicola De Maio, Yining Ding, Vijay Shahani, Nick Goldman, Matthieu Schapira
Genetic Variability of the SARS-CoV-2 Pocketome. Journal of proteome research 20 (8) (2021)
Yudao Shen, Fengling Li, Magdalena M Szewczyk, Levon Halabelian, Irene Chau, Mohammad S Eram, Carlo Dela Seña, Kwang-Su Park, Fanye Meng, He Chen, Hong Zeng, Aiping Dong, Hong Wu, Viacheslav V Trush, David McLeod, Carlos A Zepeda-Velázquez, Robert M Campbell, Mary M Mader, Brian M Watson, Matthieu Schapira, Cheryl H Arrowsmith, Rima Al-Awar, Dalia Barsyte-Lovejoy, Husnu Ümit Kaniskan, Peter J Brown, Masoud Vedadi, Jian Jin
A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6. Journal of medicinal chemistry 64 (7) (2021)
Kanchan Devkota, Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau, Pegah Ghiabi, Taraneh Hajian, Peter Loppnau, Albina Bolotokova, Karla J F Satchell, Ke Wang, Deyao Li, Jing Liu, David Smil, Minkui Luo, Jian Jin, Paul V Fish, Peter J Brown, Masoud Vedadi
Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors. bioRxiv : the preprint server for biology (2021)
David Dilworth, Ronan P Hanley, Renato Ferreira de Freitas, Abdellah Allali-Hassani, Mengqi Zhou, Naimee Mehta, Matthew R Marunde, Suzanne Ackloo, Raquel Arminda Carvalho Machado, Aliakbar Khalili Yazdi, Dominic D G Owens, Victoria Vu, David Y Nie, Mona Alqazzaz, Edyta Marcon, Fengling Li, Irene Chau, Albina Bolotokova, Su Qin, Ming Lei, Yanli Liu, Magdalena M Szewczyk, Aiping Dong, Sina Kazemzadeh, Tigran Abramyan, Irina K Popova, Nathan W Hall, Matthew J Meiners, Marcus A Cheek, Elisa Gibson, Dmitri B Kireev, Jack F Greenblatt, Michael-Christopher Keogh, Jinrong Min, Peter J Brown, Masoud Vedadi, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Lindsey I James, Matthieu Schapira
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization. Nature chemical biology (2021)
Jinyoung Lee, Matthieu Schapira
The Promise and Peril of Chemical Probe Negative Controls. ACS chemical biology 16 (4) (2021)
Mandeep K Mann, Carlos A Zepeda-Velázquez, Héctor González-Álvarez, Aiping Dong, Taira Kiyota, Ahmed M Aman, Peter Loppnau, Yanjun Li, Brian Wilson, Cheryl H Arrowsmith, Rima Al-Awar, Rachel J Harding, Matthieu Schapira
Correction to "Structure-Activity Relationship of USP5 Inhibitors". Journal of medicinal chemistry 65 (1) (2021)
Renato Ferreira de Freitas, Yanli Liu, Magdalena M Szewczyk, Naimee Mehta, Fengling Li, David McLeod, Carlos Zepeda-Velázquez, David Dilworth, Ronan P Hanley, Elisa Gibson, Peter J Brown, Rima Al-Awar, Lindsey I James, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Jinrong Min, Masoud Vedadi, Matthieu Schapira, Abdellah Allali-Hassani
Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2. Journal of medicinal chemistry 64 (3) (2021)
Qin Wu, Matthieu Schapira, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy
Protein arginine methylation: from enigmatic functions to therapeutic targeting. Nature reviews. Drug discovery 20 (7) (2021)
Rachel J Harding, Justin C Deme, Johannes F Hevler, Sem Tamara, Alexander Lemak, Jeffrey P Cantle, Magdalena M Szewczyk, Nola Begeja, Siobhan Goss, Xiao-Bing Zuo, Peter Loppnau, Alma Seitova, Ashley Hutchinson, Lixin Fan, Ray Truant, Matthieu Schapira, Jeffrey B Carroll, Albert J R Heck, Susan M Lea, Cheryl H Arrowsmith
Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. Communications biology 4 (1) (2021)
Joseph A Newman, Alice Douangamath, Setayesh Yadzani, Yuliana Yosaatmadja, Anthony Aimon, José Brandão-Neto, Louise Dunnett, Tyler Gorrie-Stone, Rachael E Skyner, Daren Fearon, Matthieu Schapira, Frank von Delft, Opher Gileadi
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nature communications 12 (1) (2021)
Aïda Bafeta, Jason R Bobe, Jon C Clucas, Pattie Pramila Gonsalves, Célya Gruson-Daniel, Kathy L Hudson, Arno Klein, Anirudh Krishnakumar, Anna McCollister-Slipp, Ariel B Lindner, Dusan Misevic, John A Naslund, Camille Nebeker, Aki Nikolaidis, Irene Pasquetto, Gabriela Sanchez, Matthieu Schapira, Tohar Scheininger, Félix Schoeller, Anibal Sólon Heinsfeld, François Taddei
Ten simple rules for open human health research. PLoS computational biology 16 (9) (2020)
Renato Ferreira de Freitas, Danton Ivanochko, Matthieu Schapira
Methyltransferase Inhibitors: Competing with, or Exploiting the Bound Cofactor. Molecules (Basel, Switzerland) 24 (24) (2019)
Sebastian Scheer, Suzanne Ackloo, Tiago S Medina, Matthieu Schapira, Fengling Li, Jennifer A Ward, Andrew M Lewis, Jeffrey P Northrop, Paul L Richardson, Husnu Ümit Kaniskan, Yudao Shen, Jing Liu, David Smil, David A McLeod, Carlos A Zepeda-Velazquez, Minkui Luo, Jian Jin, Dalia Barsyte-Lovejoy, Kilian V M Huber, Daniel D De Carvalho, Masoud Vedadi, Colby Zaph, Peter J Brown, Cheryl H Arrowsmith
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nature communications 10 (1) (2019)
Matthieu Schapira, null null, Rachel J Harding
Open laboratory notebooks: good for science, good for society, good for scientists. F1000Research 8 (2019)
Abdellah Allali-Hassani, Magdalena M Szewczyk, Danton Ivanochko, Shawna L Organ, Jabez Bok, Jessica Sook Yuin Ho, Florence P H Gay, Fengling Li, Levi Blazer, Mohammad S Eram, Levon Halabelian, David Dilworth, Genna M Luciani, Evelyne Lima-Fernandes, Qin Wu, Peter Loppnau, Nathan Palmer, S Zakiah A Talib, Peter J Brown, Matthieu Schapira, Philipp Kaldis, Ronan C O'Hagan, Ernesto Guccione, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, John M Sanders, Solomon D Kattar, David Jonathan Bennett, Benjamin Nicholson, Masoud Vedadi
Discovery of a chemical probe for PRDM9. Nature communications 10 (1) (2019)
Alexandria P Taylor, Magdalena Swewczyk, Steven Kennedy, Viacheslav V Trush, Hong Wu, Hong Zeng, Aiping Dong, Renato Ferreira de Freitas, John Tatlock, Robert A Kumpf, Martin Wythes, Agustin Casimiro-Garcia, Rajiah Aldrin Denny, Mihir D Parikh, Fengling Li, Dalia Barsyte-Lovejoy, Matthieu Schapira, Masoud Vedadi, Peter J Brown, Cheryl H Arrowsmith, Dafydd R Owen
Selective, Small-Molecule Co-Factor Binding Site Inhibition of a Su(var)3-9, Enhancer of Zeste, Trithorax Domain Containing Lysine Methyltransferase. Journal of medicinal chemistry 62 (17) (2019)
Matthieu Schapira, null null, Rachel J Harding
Open laboratory notebooks: good for science, good for society, good for scientists. F1000Research (2019)
Matthieu Schapira, Matthew F Calabrese, Alex N Bullock, Craig M Crews
Targeted protein degradation: expanding the toolbox. Nature reviews. Drug discovery 18 (12) (2019)
Cheryl H Arrowsmith, Matthieu Schapira
Targeting non-bromodomain chromatin readers. Nature structural & molecular biology 26 (10) (2019)
Mandeep K Mann, Ivan Franzoni, Renato Ferreira de Freitas, Wolfram Tempel, Scott Houliston, Leanna Smith, Masoud Vedadi, Cheryl H Arrowsmith, Rachel J Harding, Matthieu Schapira
Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain. Journal of medicinal chemistry 62 (22) (2019)
Renato Ferreira de Freitas, Rachel J Harding, Ivan Franzoni, Mani Ravichandran, Mandeep K Mann, Hui Ouyang, Mark Lautens, Vijayaratnam Santhakumar, Cheryl H Arrowsmith, Matthieu Schapira
Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. Journal of medicinal chemistry 61 (10) (2018)
H Ümit Kaniskan, Mohammad S Eram, Kehao Zhao, Magdalena M Szewczyk, Xiaobao Yang, Keith Schmidt, Xiao Luo, Sean Xiao, Miao Dai, Feng He, Irene Zang, Ying Lin, Fengling Li, Elena Dobrovetsky, David Smil, Sun-Joon Min, Jennifer Lin-Jones, Matthieu Schapira, Peter Atadja, En Li, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, Peter J Brown, Feng Liu, Zhengtian Yu, Masoud Vedadi, Jian Jin
Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3). Journal of medicinal chemistry 61 (3) (2018)
Richard Song, Zhong-Duo Wang, Matthieu Schapira
Disease Association and Druggability of WD40 Repeat Proteins. Journal of proteome research 16 (10) (2017)
Renato Ferreira de Freitas, Matthieu Schapira
A systematic analysis of atomic protein-ligand interactions in the PDB. MedChemComm 8 (10) (2017)
Rachel J Harding, Renato Ferreira de Freitas, Patrick M Collins, Ivan Franzoni, Mani Ravichandran, Hui Ouyang, Kevin A Juarez-Ornelas, Mark Lautens, Matthieu Schapira, Frank von Delft, Vjayaratnam Santhakumar, Cheryl H Arrowsmith
Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin. Journal of medicinal chemistry 60 (21) (2017)