Robert E W Hancock (Robert E Hancock)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 44

Top Venues

Nature communications

Antimicrobial agents and chemotherapy

Molecular pharmaceutics

Nature protocols

University of British Columbia Faculty of Science

University of Adelaide (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of British Columbia Faculty of Science Jun 01 1978

Canada

Professor and Canada Research Chair :: Microbiology and Immunology

Education History

University of Adelaide Jan 01 1971 - Mar 01 1975

Australia

PHD :: Microbiology

University of Adelaide Jan 01 1967 - Jan 01 1971

Australia

BSC :: Microbiology

Publications

Tullio V F Esposito, Colin Blackadar, Lan Wu, Cristina Rodríguez-Rodríguez, Evan F Haney, Daniel Pletzer, Katayoun Saatchi, Robert E W Hancock, Urs O Häfeli
Biodistribution of Native and Nanoformulated Innate Defense Regulator Peptide 1002. Molecular pharmaceutics 21 (6) (2024)
David J Martino, Nina Kresoje, Nelly Amenyogbe, Rym Ben-Othman, Bing Cai, Mandy Lo, Olubukola Idoko, Oludare A Odumade, Reza Falsafi, Travis M Blimkie, Andy An, Casey P Shannon, Sebastiano Montante, Bhavjinder Kaur Dhillon, Joann Diray-Arce, Al Ozonoff, Kinga K Smolen, Ryan R Brinkman, Kerry McEnaney, Asimenia Angelidou, Peter Richmond, Scott J Tebbutt, null null, Beate Kampmann, Ofer Levy, Robert E W Hancock, Amy H Y Lee, Tobias R Kollmann
DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life. Nature communications 15 (1) (2024)
Tullio V F Esposito, Colin Blackadar, Lan Wu, Cristina Rodríguez-Rodríguez, Evan F Haney, Daniel Pletzer, Katayoun Saatchi, Robert E W Hancock, Urs O Häfeli
Biodistribution of Native and Nanoformulated Innate Defense Regulator Peptide 1002. Molecular pharmaceutics 21 (6) (2024)
Travis M Blimkie, Andy An, Robert E W Hancock
Facilitating pathway and network based analysis of RNA-Seq data with pathlinkR. PLoS computational biology 20 (9) (2024)
Tullio V F Esposito, Colin Blackadar, Lan Wu, Cristina Rodríguez-Rodríguez, Evan F Haney, Daniel Pletzer, Katayoun Saatchi, Robert E W Hancock, Urs O Häfeli
Biodistribution of Native and Nanoformulated Innate Defense Regulator Peptide 1002. Molecular pharmaceutics (2024)
Shahid Chaudhary, Zahir Ali, Muhammad Tehseen, Evan F Haney, Aarón Pantoja-Angles, Salwa A Alshehri, Tiannyu Wang, Gerard J Clancy, Maya Ayach, Charlotte A E Hauser, Pei-Ying Hong, Samir M Hamdan, Robert E W Hancock, Magdy M Mahfouz
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens. Nature communications 14 (1) (2023)
Shahid Chaudhary, Zahir Ali, Muhammad Tehseen, Evan F Haney, Aarón Pantoja-Angles, Salwa A Alshehri, Tiannyu Wang, Gerard J Clancy, Maya Ayach, Charlotte A E Hauser, Pei-Ying Hong, Samir M Hamdan, Robert E W Hancock, Magdy M Mahfouz
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens. Nature communications 14 (1) (2023)
Shahid Chaudhary, Zahir Ali, Muhammad Tehseen, Evan F Haney, Aarón Pantoja-Angles, Salwa A Alshehri, Tiannyu Wang, Gerard J Clancy, Maya Ayach, Charlotte A E Hauser, Pei-Ying Hong, Samir M Hamdan, Robert E W Hancock, Magdy M Mahfouz
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens. Nature communications 14 (1) (2023)
Hashem Etayash, Fione Yip, Robert E W Hancock
Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018. Pharmaceutics 15 (5) (2023)
Shahid Chaudhary, Zahir Ali, Muhammad Tehseen, Evan F Haney, Aarón Pantoja-Angles, Salwa A Alshehri, Tiannyu Wang, Gerard J Clancy, Maya Ayach, Charlotte A E Hauser, Pei-Ying Hong, Samir M Hamdan, Robert E W Hancock, Magdy M Mahfouz
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens. Nature communications 14 (1) (2023)
Josefine Eilsø Nielsen, Morgan Ashley Alford, Deborah Bow Yue Yung, Natalia Molchanova, John A Fortkort, Jennifer S Lin, Gill Diamond, Robert E W Hancock, Håvard Jenssen, Daniel Pletzer, Reidar Lund, Annelise E Barron
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens. ACS infectious diseases 8 (3) (2022)
Felix L Santana, Karel Estrada, Morgan Ashley Alford, Bing Catherine Wu, Melanie Dostert, Lucas Pedraz, Noushin Akhoundsadegh, Pavneet Kalsi, Evan F Haney, Suzana K Straus, Gerardo A Corzo, Robert E W Hancock
Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens. Antibiotics (Basel, Switzerland) 11 (11) (2022)
Hashem Etayash, Morgan Ashley Alford, Noushin Akhoundsadegh, Matthew Drayton, Suzana K Straus, Robert E W Hancock
Correction to "Multifunctional Antibiotic-Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response". Journal of medicinal chemistry 65 (3) (2022)
Shannon R Coleman, Daniel Pletzer, Robert E W Hancock
Contribution of Swarming Motility to Dissemination in a Pseudomonas aeruginosa Murine Skin Abscess Infection Model. The Journal of infectious diseases 224 (4) (2022)
Kenneth C Smith, Daniel G Chawla, Bhavjinder Kaur Dhillon, Zhou Ji, Randi Vita, Eva C van der Leest, Jing Yi Jessica Weng, Ernest Tang, Amani Abid, null null, Bjoern Peters, Robert E W Hancock, Aris Floratos, Steven H Kleinstein
A curated collection of human vaccination response signatures. Scientific data 9 (1) (2022)
Christina L Wiesmann, Yue Zhang, Morgan Ashley Alford, Corri D Hamilton, Manisha Dosanjh, David Thoms, Melanie Dostert, Andrew J Wilson, Daniel Pletzer, Robert E W Hancock, Cara H Haney
The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species. The ISME journal (2022)
Bing Catherine Wu, Travis M Blimkie, Evan F Haney, Reza Falsafi, Noushin Akhoundsadegh, Robert E W Hancock
Host Response of Human Epidermis to Methicillin-Resistant Staphylococcus aureus Biofilm Infection and Synthetic Antibiofilm Peptide Treatment. Cells 11 (21) (2022)
Colin Blackadar, Ka-Yee Grace Choi, Mary F Embree, Heather M Hennkens, Cristina Rodríguez-Rodríguez, Robert E W Hancock, Katayoun Saatchi, Urs O Häfeli
SPECT/CT Imaging of 111 Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines. ACS applied materials & interfaces (2022)
Noorjahan Aibani, Parth Patel, Rachelle Buchanan, Stacy Strom, Kishor M Wasan, Robert E W Hancock, Volker Gerdts, Ellen K Wasan
Assessing the In Vivo Effectiveness of Cationic Lipid Nanoparticles with a Triple Adjuvant for Intranasal Vaccination against the Respiratory Pathogen Bordetella pertussis . Molecular pharmaceutics 19 (6) (2022)
Katharine Sedivy-Haley, Travis Blimkie, Reza Falsafi, Amy Huei-Yi Lee, Robert E W Hancock
A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella. PloS one 17 (10) (2022)
Hashem Etayash, Evan F Haney, Robert E W Hancock
Assessing biofilm inhibition and immunomodulatory activity of small amounts of synthetic host defense peptides synthesized using SPOT-array technology. Nature protocols 16 (4) (2021)
Evan F Haney, Michael J Trimble, Robert E W Hancock
Microtiter plate assays to assess antibiofilm activity against bacteria. Nature protocols 16 (5) (2021)
Corrie R Belanger, Robert E W Hancock
Testing physiologically relevant conditions in minimal inhibitory concentration assays. Nature protocols 16 (8) (2021)
Hashem Etayash, Robert E W Hancock
Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success. Pharmaceutics 13 (11) (2021)
Kai Yu, Amal Alzahrani, Sara Khoddami, John T J Cheng, Yan Mei, Arshdeep Gill, Haiming D Luo, Evan F Haney, Kai Hilpert, Robert E W Hancock, Dirk Lange, Jayachandran N Kizhakkedathu
Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background. ACS applied materials & interfaces 13 (31) (2021)
Robert E W Hancock, Morgan Ashley Alford, Evan F Haney
Antibiofilm activity of host defence peptides: complexity provides opportunities. Nature reviews. Microbiology 19 (12) (2021)
Hashem Etayash, Morgan Ashley Alford, Noushin Akhoundsadegh, Matthew Drayton, Suzana K Straus, Robert E W Hancock
Multifunctional Antibiotic-Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response. Journal of medicinal chemistry 64 (22) (2021)
Shannon R Coleman, Manjeet Bains, Maren L Smith, Victor Spicer, Ying Lao, Patrick K Taylor, Neeloffer Mookherjee, Robert E W Hancock
The Small RNAs PA2952.1 and PrrH as Regulators of Virulence, Motility, and Iron Metabolism in Pseudomonas aeruginosa. Applied and environmental microbiology 87 (3) (2021)
Bing Catherine Wu, Evan F Haney, Noushin Akhoundsadegh, Daniel Pletzer, Michael J Trimble, Alwin E Adriaans, Peter H Nibbering, Robert E W Hancock
Human organoid biofilm model for assessing antibiofilm activity of novel agents. NPJ biofilms and microbiomes 7 (1) (2021)
Janine N Copp, Daniel Pletzer, Alistair S Brown, Joris Van der Heijden, Charlotte M Miton, Rebecca J Edgar, Michelle H Rich, Rory F Little, Elsie M Williams, Robert E W Hancock, Nobuhiko Tokuriki, David F Ackerley
Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections. mBio 11 (5) (2020)
Daniel Pletzer, Evelyn Sun, Caleb Ritchie, Lauren Wilkinson, Leo T Liu, Michael J Trimble, Heidi Wolfmeier, Travis M Blimkie, Robert E W Hancock
Surfing motility is a complex adaptation dependent on the stringent stress response in Pseudomonas aeruginosa LESB58. PLoS pathogens 16 (3) (2020)
Ashley L Hilchie, Erin E Gill, Melanie R Power Coombs, Reza Falsafi, Robert E W Hancock, David W Hoskin
MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity. Biomolecules 10 (9) (2020)
Iván Arenas, Marco Antonio Ibarra, Felix L Santana, Elba Villegas, Robert E W Hancock, Gerardo A Corzo
In Vitro and In Vivo Antibiotic Capacity of Two Host Defense Peptides. Antimicrobial agents and chemotherapy 64 (7) (2020)
Shannon R Coleman, Maren L Smith, Victor Spicer, Ying Lao, Neeloffer Mookherjee, Robert E W Hancock
Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin Resistance. mSystems 5 (3) (2020)
Kelly M Khomtchouk, Ali Kouhi, Anping Xia, Laurent Adonis Bekale, Solange M Massa, Johanna M Sweere, Daniel Pletzer, Robert E W Hancock, Paul L Bollyky, Peter L Santa Maria
A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation. Science advances 6 (33) (2020)
Daniel Pletzer, Travis M Blimkie, Heidi Wolfmeier, Yicong Li, Arjun Baghela, Amy H Y Lee, Reza Falsafi, Robert E W Hancock
The Stringent Stress Response Controls Proteases and Global Regulators under Optimal Growth Conditions in Pseudomonas aeruginosa. mSystems 5 (4) (2020)
Shannon R Coleman, Travis Blimkie, Reza Falsafi, Robert E W Hancock
Multidrug Adaptive Resistance of Pseudomonas aeruginosa Swarming Cells. Antimicrobial agents and chemotherapy 64 (3) (2020)
Noushin Akhoundsadegh, Corrie R Belanger, Robert E W Hancock
Outer Membrane Interaction Kinetics of New Polymyxin B Analogs in Gram-Negative Bacilli. Antimicrobial agents and chemotherapy 63 (10) (2019)
Amy T Y Yeung, Yoon Ha Choi, Amy H Y Lee, Christine Hale, Hannes Ponstingl, Derek Pickard, David Goulding, Mark Thomas, Erin Gill, Jong Kyoung Kim, Allan Bradley, Robert E W Hancock, Gordon Dougan
A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection. mBio 10 (5) (2019)
Morgan Ashley Alford, Daniel Pletzer, Robert E W Hancock
Dismantling the bacterial virulence program. Microbial biotechnology 12 (3) (2019)
Maytham Hussein, Mei-Ling Han, Yan Zhu, Qi Zhou, Yu-Wei Lin, Robert E W Hancock, Daniel Hoyer, Darren John Creek, Jian Li, Tony Velkov
Metabolomics Study of the Synergistic Killing of Polymyxin B in Combination with Amikacin against Polymyxin-Susceptible and -Resistant Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy 64 (1) (2019)
Kelli Wuerth, Amy Huei-Yi Lee, Reza Falsafi, Erin E Gill, Robert E W Hancock
Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002. Infection and immunity 87 (1) (2018)
Daniel Pletzer, Sarah C Mansour, Robert E W Hancock
Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens. PLoS pathogens 14 (6) (2018)
Kelli C Wuerth, Reza Falsafi, Robert E W Hancock
Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection. PloS one 12 (11) (2017)

Robert E W Hancock.css-eqlu8i{font-size:small;padding-left:4px;} (Robert E Hancock)

Publication Activity (10 Years)

Top Topics

Top Venues

Robert E W Hancock (Robert E Hancock)