Argyrides Argyrou

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 20

Top Venues

Journal of medicinal chemistry

Biochemistry

ACS medicinal chemistry letters

Proceedings of the National Academy of Sciences of the United States of America

IMED Biotech Unit, AstraZeneca

This page only lists publications with an associated author ORCID identifier.

Affiliation History

IMED Biotech Unit, AstraZeneca Jul 31 2018

United Kingdom

Associate Principal Sicientist :: Discovery Biology, Discovery Sciences

GlaxoSmithKline

United Kingdom

Group Leader/Manager :: Department of Biological Sciences

GlaxoSmithKline

United Kingdom

Team Leader/Investigator :: Department of Biological Reagents & Assay Development

Bristol-Myers Squibb Co

United States

Senior Research Investigator :: Department of Chemical Enzymology

Yeshiva University Albert Einstein College of Medicine

United States

Instructor of Biochemistry :: Department of Biochemistry

Yeshiva University Albert Einstein College of Medicine

United States

Post-doctoral research associate :: Department of Biochemistry

Publications

Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Sharan K Bagal, Peter C Astles, Coura R Diene, Argyrides Argyrou, Claire Crafter, Doyle J Cassar, Charlene Fallan, Andreas Hock, Thomas Jones, Kevin Moreau, Gillian M Lamont, Scott Lamont, Chrysiis Michaloglou, Martin J Packer, Andy Pike, Antonio Ramos-Montoya, James S Scott, Joseph Shaw, Ziyanda Shologu
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. Journal of medicinal chemistry 67 (14) (2024)
Nils Pemberton, Nina Compagne, Argyrides Argyrou, Emma Evertsson, Anders Gunnarsson, Jason G Kettle, Jonathan P Orme, Richard A Ward
Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR. ACS medicinal chemistry letters 15 (5) (2024)
Nils Pemberton, Nina Compagne, Argyrides Argyrou, Emma Evertsson, Anders Gunnarsson, Jason G Kettle, Jonathan P Orme, Richard A Ward
Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR. ACS medicinal chemistry letters 15 (5) (2024)
Simon C C Lucas, Afshan Ahmed, S Neha Ashraf, Argyrides Argyrou, Matthias R Bauer, Gian Marco De Donatis, Sylvain Demanze, Frederik Eisele, Lucia Fusani, Andreas Hock, Ganesh Kadamur, Shuyou Li, Abigail Macmillan-Jones, Iacovos N Michaelides, Christopher Phillips, Marie Rehnström, Magdalena Richter, Monica C Rodrigo-Brenni, Fiona Shilliday, Peng Wang, R Ian Storer
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. Journal of medicinal chemistry (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
Sharan K Bagal, Peter C Astles, Coura R Diene, Argyrides Argyrou, Claire Crafter, Doyle J Cassar, Charlene Fallan, Andreas Hock, Thomas Jones, Kevin Moreau, Gillian M Lamont, Scott Lamont, Chrysiis Michaloglou, Martin J Packer, Andy Pike, Antonio Ramos-Montoya, James S Scott, Joseph Shaw, Ziyanda Shologu
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. Journal of medicinal chemistry 67 (14) (2024)
Simon C C Lucas, Afshan Ahmed, S Neha Ashraf, Argyrides Argyrou, Matthias R Bauer, Gian Marco De Donatis, Sylvain Demanze, Frederik Eisele, Lucia Fusani, Andreas Hock, Ganesh Kadamur, Shuyou Li, Abigail Macmillan-Jones, Iacovos N Michaelides, Christopher Phillips, Marie Rehnström, Magdalena Richter, Monica C Rodrigo-Brenni, Fiona Shilliday, Peng Wang, R Ian Storer
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. Journal of medicinal chemistry 67 (7) (2024)
Sharan K Bagal, Peter C Astles, Coura R Diene, Argyrides Argyrou, Claire Crafter, Doyle J Cassar, Charlene Fallan, Andreas Hock, Thomas Jones, Kevin Moreau, Gillian M Lamont, Scott Lamont, Chrysiis Michaloglou, Martin J Packer, Andy Pike, Antonio Ramos-Montoya, James S Scott, Joseph Shaw, Ziyanda Shologu
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. Journal of medicinal chemistry 67 (14) (2024)
Sharan K Bagal, Peter C Astles, Coura R Diene, Argyrides Argyrou, Claire Crafter, Doyle J Cassar, Charlene Fallan, Andreas Hock, Thomas Jones, Kevin Moreau, Gillian M Lamont, Scott Lamont, Chrysiis Michaloglou, Martin J Packer, Andy Pike, Antonio Ramos-Montoya, James S Scott, Joseph Shaw, Ziyanda Shologu
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. Journal of medicinal chemistry (2024)
Simon C C Lucas, Afshan Ahmed, S Neha Ashraf, Argyrides Argyrou, Matthias R Bauer, Gian Marco De Donatis, Sylvain Demanze, Frederik Eisele, Lucia Fusani, Andreas Hock, Ganesh Kadamur, Shuyou Li, Abigail Macmillan-Jones, Iacovos N Michaelides, Christopher Phillips, Marie Rehnström, Magdalena Richter, Monica C Rodrigo-Brenni, Fiona Shilliday, Peng Wang, R Ian Storer
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. Journal of medicinal chemistry 67 (7) (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry (2024)
Claudia De Fusco, Marianne Schimpl, Ulf Börjesson, Tony Cheung, Iain Collie, Laura Evans, Priyanka Narasimhan, Christopher Stubbs, Mercedes Vazquez-Chantada, David J Wagner, Michael Grondine, Matthew G Sanders, Sharon Tentarelli, Elizabeth Underwood, Argyrides Argyrou, James M Smith, James T Lynch, Elisabetta Chiarparin, Graeme R Robb, Sharan K Bagal, James S Scott
Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model. Journal of medicinal chemistry 64 (10) (2021)
Jonathan Bailey, Holly Douglas, Laura Masino, Luiz Pedro Sorio de Carvalho, Argyrides Argyrou
Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B. Biochemistry 60 (47) (2021)
Jennifer A Borthwick, Carlos Alemparte, Ian Wall, Benjamin C Whitehurst, Argyrides Argyrou, Glenn A Burley, Paco de Dios-Anton, Laura Guijarro, Maria Candida Monteiro, Fatima Ortega, Colin J Suckling, Julia Castro Pichel, Mónica Cacho, Robert J Young
Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity. Journal of medicinal chemistry 63 (5) (2020)
Xiang Zhai, Richard A Ward, Peter Doig, Argyrides Argyrou
Insight into the Therapeutic Selectivity of the Irreversible EGFR Tyrosine Kinase Inhibitor Osimertinib through Enzyme Kinetic Studies. Biochemistry 59 (14) (2020)
Maciej K Rogacki, Eleni Pitta, Olga Balabon, Sophie Huss, Eva Maria Lopez-Roman, Argyrides Argyrou, Delia Blanco-Ruano, Monica Cacho, Christophe M L Vande Velde, Koen Augustyns, Lluis Ballell, David Barros Aguirre, Robert H Bates, Fraser Cunningham, Pieter Van Der Veken
Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors. Journal of medicinal chemistry 61 (24) (2018)
Thulasi Warrier, Kanishk Kapilashrami, Argyrides Argyrou, Thomas R Ioerger, David Little, Kenan C Murphy, Madhumitha Nandakumar, Suna Park, Ben Gold, Jianjie Mi, Tuo Zhang, Eugenia Meiler, Mike Rees, Selin Somersan-Karakaya, Esther Porras-De Francisco, Maria Martinez-Hoyos, Kristin Burns-Huang, Julia Roberts, Yan Ling, Kyu Y Rhee, Alfonso Mendoza-Losana, Minkui Luo, Carl F Nathan
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America 113 (31) (2016)
Katherine A Abrahams, Chun-Wa Chung, Sonja Ghidelli-Disse, Joaquín Rullas, María José Rebollo-López, Sudagar S Gurcha, Jonathan A G Cox, Alfonso Mendoza, Elena Jiménez-Navarro, María Santos Martínez-Martínez, Margarete Neu, Anthony Shillings, Paul Homes, Argyrides Argyrou, Ruth Casanueva, Nicholas J Loman, Patrick J Moynihan, Joël Lelièvre, Carolyn Selenski, Matthew Axtman, Laurent Kremer, Marcus Bantscheff, Iñigo Angulo-Barturen, Mónica Cacho Izquierdo, Nicholas C Cammack, Gerard Drewes, Lluis Ballell, David Barros, Gurdyal S Besra, Robert H Bates
Identification of KasA as the cellular target of an anti-tubercular scaffold. Nature communications 7 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Argyrides Argyrou