Dinshaw J Patel

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 52

Top Topics

Dna Methylation

Top Venues

Nature structural & molecular biology

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Christian F Baca, You Yu, Jakob T Rostøl, Puja Majumder, Dinshaw J Patel, Luciano A Marraffini
The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature 625 (7996) (2024)
Christian F Baca, You Yu, Jakob T Rostøl, Puja Majumder, Dinshaw J Patel, Luciano A Marraffini
The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature 625 (7996) (2024)
You Yu, Juncheng Wang, Kaixian Liu, Zhi Zheng, Meret Arter, Corentin Claeys Bouuaert, Stephen Pu, Dinshaw J Patel, Scott Keeney
Cryo-EM structures of the Spo11 core complex bound to DNA. Nature structural & molecular biology (2024)
Hui Yang, Dinshaw J Patel
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease. Cell research 34 (7) (2024)
Christian F Baca, You Yu, Jakob T Rostøl, Puja Majumder, Dinshaw J Patel, Luciano A Marraffini
The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature 625 (7996) (2024)
Christian F Baca, You Yu, Jakob T Rostøl, Puja Majumder, Dinshaw J Patel, Luciano A Marraffini
The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature 625 (7996) (2024)
Hui Yang, Dinshaw J Patel
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease. Cell research 34 (7) (2024)
Hui Yang, Dinshaw J Patel
Structures, mechanisms and applications of RNA-centric CRISPR-Cas13. Nature chemical biology 20 (6) (2024)
Hui Yang, Dinshaw J Patel
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease. Cell research 34 (7) (2024)
Hui Yang, Dinshaw J Patel
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease. Cell research 34 (7) (2024)
Hui Yang, Dinshaw J Patel
Structures, mechanisms and applications of RNA-centric CRISPR-Cas13. Nature chemical biology 20 (6) (2024)
Hui Yang, Dinshaw J Patel
Structures, mechanisms and applications of RNA-centric CRISPR-Cas13. Nature chemical biology (2024)
Hui Yang, Dinshaw J Patel
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease. Cell research (2024)
Christian F Baca, You Yu, Jakob T Rostøl, Puja Majumder, Dinshaw J Patel, Luciano A Marraffini
The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature (2024)
Christian F Baca, You Yu, Jakob T Rostøl, Puja Majumder, Dinshaw J Patel, Luciano A Marraffini
The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature 625 (7996) (2024)
Hui Yang, Dinshaw J Patel
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease. Cell research 34 (7) (2024)
Wei Xie, Dinshaw J Patel
A 'warhorse-shaped' topology adopted by the m 6 A RNA writer complex. Cell research 33 (1) (2023)
Arpita Chakravarti, Dinshaw J Patel
Atypical bacterial Argonautes regulate antiphage defense. Cell research (2023)
Wei Xie, Dinshaw J Patel
A 'warhorse-shaped' topology adopted by the m 6 A RNA writer complex. Cell research (2023)
Dinshaw J Patel, You Yu, Wei Xie
cGAMP-activated cGAS-STING signaling: its bacterial origins and evolutionary adaptation by metazoans. Nature structural & molecular biology (2023)
Wei Xie, Dinshaw J Patel
A 'warhorse-shaped' topology adopted by the m 6 A RNA writer complex. Cell research 33 (1) (2023)
Dinshaw J Patel, You Yu, Wei Xie
cGAMP-activated cGAS-STING signaling: its bacterial origins and evolutionary adaptation by metazoans. Nature structural & molecular biology 30 (3) (2023)
Dinshaw J Patel, You Yu, Wei Xie
cGAMP-activated cGAS-STING signaling: its bacterial origins and evolutionary adaptation by metazoans. Nature structural & molecular biology 30 (3) (2023)
Shibai Li, You Yu, Jian Zheng, Victoria Miller-Browne, Zheng Ser, Huihui Kuang, Dinshaw J Patel, Xiaolan Zhao
Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions. Proceedings of the National Academy of Sciences of the United States of America 120 (45) (2023)
Hui Yang, Dinshaw J Patel
Fanzors: Striking expansion of RNA-guided endonucleases to eukaryotes. Cell research (2023)
Wei Xie, Dinshaw J Patel
A 'warhorse-shaped' topology adopted by the m 6 A RNA writer complex. Cell research 33 (1) (2023)
You Yu, Juncheng Wang, Kaixian Liu, Zhi Zheng, Meret Arter, Corentin Claeys Bouuaert, Stephen Pu, Dinshaw J Patel, Scott Keeney
Cryo-EM structure of the Spo11 core complex bound to DNA. bioRxiv : the preprint server for biology (2023)
Dinshaw J Patel, You Yu, Wei Xie
cGAMP-activated cGAS-STING signaling: its bacterial origins and evolutionary adaptation by metazoans. Nature structural & molecular biology 30 (3) (2023)
Wei Xie, Dinshaw J Patel
A 'warhorse-shaped' topology adopted by the m 6 A RNA writer complex. Cell research 33 (1) (2023)
Veselin I Andreev, Changwei Yu, Juncheng Wang, Jakob Schnabl, Laszlo Tirian, Maja Gehre, Dominik Handler, Peter Duchek, Maria Novatchkova, Lisa Baumgartner, Katharina Meixner, Grzegorz Sienski, Dinshaw J Patel, Julius Brennecke
Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery. Nature structural & molecular biology 29 (2) (2022)
Wei Xie, Kai Wucherpfennig, Dinshaw J Patel
A structural platform for B cell receptor signaling. Cell research (2022)
Xuanting Wang, Carolina Q Sacramento, Steffen Jockusch, Otávio Augusto Chaves, Chuanjuan Tao, Natalia Fintelman-Rodrigues, Minchen Chien, Jairo Ramos Temerozo, Xiaoxu Li, Shiv Kumar, Wei Xie, Dinshaw J Patel, Cindy Meyer, Aitor Garzia, Thomas Tuschl, Patrícia Torres Bozza, James J Russo, Thiago Moreno L Souza, Jingyue Ju
Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture. Communications biology 5 (1) (2022)
Hui Yang, Dinshaw J Patel
A type III-E CRISPR Craspase exhibiting RNase and protease activities. Cell research 32 (12) (2022)
Jiamu Du, Dinshaw J Patel
Cofactor-assisted dicing: insights from structural snapshots. Cell research 32 (11) (2022)
Riward A Campelo Morillo, Xinran Tong, Wei Xie, Steven Abel, Lindsey M Orchard, Wassim Daher, Dinshaw J Patel, Manuel Llinás, Karine G Le Roch, Björn F C Kafsack
The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites. Nature microbiology 7 (2) (2022)
You Yu, Shibai Li, Zheng Ser, Huihui Kuang, Thane Than, Danying Guan, Xiaolan Zhao, Dinshaw J Patel
Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes. Proceedings of the National Academy of Sciences of the United States of America 119 (23) (2022)
Ning Jia, Dinshaw J Patel
Structure-based evolutionary relationship between IscB and Cas9. Cell research 32 (10) (2022)
Ning Jia, Dinshaw J Patel
Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins. Nature reviews. Molecular cell biology 22 (8) (2021)
Xiawei Huang, Hongmiao Hu, Alexandre Webster, Fan Zou, Jiamu Du, Dinshaw J Patel, Ravi Sachidanandam, Katalin Fejes Toth, Alexei A Aravin, Sisi Li
Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex. Nature communications 12 (1) (2021)
Wendan Ren, Huitao Fan, Sara A Grimm, Jae Jin Kim, Linhui Li, Yiran Guo, Christopher James Petell, Xiao-Feng Tan, Zhi-Min Zhang, John P Coan, Jiekai Yin, Dae In Kim, Linfeng Gao, Ling Cai, Nelli Khudaverdyan, Burak Çetin, Dinshaw J Patel, Yinsheng Wang, Qiang Cui, Brian D Strahl, Or Gozani, Kyle M Miller, Seán E O'Leary, Paul A Wade, Gang Greg Wang, Jikui Song
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nature communications 12 (1) (2021)
Wei Xie, Shengliu Wang, Juncheng Wang, M Jason de la Cruz, Guotai Xu, Maurizio Scaltriti, Dinshaw J Patel
Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proceedings of the National Academy of Sciences of the United States of America 118 (8) (2021)
You Yu, Shibai Li, Zheng Ser, Tanmoy Sanyal, Koyi Choi, Bingbing Wan, Huihui Kuang, Andrej Sali, Alex Kentsis, Dinshaw J Patel, Xiaolan Zhao
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Jakob T Rostøl, Wei Xie, Vitaly Kuryavyi, Pascal Maguin, Kevin Kao, Ruby Froom, Dinshaw J Patel, Luciano A Marraffini
The Card1 nuclease provides defence during type III CRISPR immunity. Nature 590 (7847) (2021)
Corentin Claeys Bouuaert, Stephen Pu, Juncheng Wang, Cédric A Oger, Dima Daccache, Wei Xie, Dinshaw J Patel, Scott Keeney
DNA-driven condensation assembles the meiotic DNA break machinery. Nature 592 (7852) (2021)
Wendan Ren, Huitao Fan, Sara A Grimm, Yiran Guo, Jae Jin Kim, Jiekai Yin, Linhui Li, Christopher J Petell, Xiao-Feng Tan, Zhi-Min Zhang, John P Coan, Linfeng Gao, Ling Cai, Brittany Detrick, Burak Çetin, Qiang Cui, Brian D Strahl, Or Gozani, Yinsheng Wang, Kyle M Miller, Seán E O'Leary, Paul A Wade, Dinshaw J Patel, Gang Greg Wang, Jikui Song
Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation. Proceedings of the National Academy of Sciences of the United States of America 117 (31) (2020)
Zhichiao Miao, Ryszard W Adamiak, Maciej Antczak, Michał J Boniecki, Janusz M Bujnicki, Shi-Jie Chen, Clarence Yu Cheng, Yi Cheng, Fang-Chieh Chou, Rachel J Hagey, Nikolay V Dokholyan, Feng Ding, Caleb Geniesse, Yangwei Jiang, Astha Joshi, Andrey Krokhotin, Marcin Magnus, Olivier Mailhot, Francois Major, Thomas H Mann, Paweł Piątkowski, Radoslaw Pluta, Mariusz Popenda, Joanna Sarzyńska, Lizhen Sun, Marta Szachniuk, Siqi Tian, Jian Wang, Jun Wang, Andrew M Watkins, Jakub Wiedemann, Yi Xiao, Xiaojun Xu, Joseph D Yesselman, Dong Zhang, Yi Zhang, Zhenzhen Zhang, Chenhan Zhao, Peinan Zhao, Yuanzhe Zhou, Tomasz Zok, Adriana Żyła, Aiming Ren, Robert T Batey, Barbara L Golden, Lin Huang, David M J Lilley, Yijin Liu, Dinshaw J Patel, Eric Westhof
RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers. RNA (New York, N.Y.) 26 (8) (2020)
Wanqiu Li, Wei Tian, Gang Yuan, Pujuan Deng, Deepanwita Sengupta, Zhongjun Cheng, Yinghua Cao, Jiahao Ren, Yan Qin, Yuqiao Zhou, Yulin Jia, Or Gozani, Dinshaw J Patel, Zhanxin Wang
Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature 590 (7846) (2020)
Wei Xie, Ivica Sowemimo, Rippei Hayashi, Juncheng Wang, Thomas R Burkard, Julius Brennecke, Stefan L Ameres, Dinshaw J Patel
Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Alexander J Meeske, Ning Jia, Alice K Cassel, Albina Kozlova, Jingqiu Liao, Martin Wiedmann, Dinshaw J Patel, Luciano A Marraffini
A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity. Science (New York, N.Y.) 369 (6499) (2020)
Gerard Minuesa, Steven K Albanese, Wei Xie, Yaniv Kazansky, Daniel Worroll, Arthur Chow, Alexandra Schurer, Sun-Mi Park, Christina Z Rotsides, James Taggart, Andrea Rizzi, Levi N Naden, Timothy Chou, Saroj Gourkanti, Daniel Cappel, Maria C Passarelli, Lauren Fairchild, Carolina Adura, J Fraser Glickman, Jessica Schulman, Christopher Famulare, Minal Patel, Joseph K Eibl, Gregory M Ross, Shibani Bhattacharya, Derek S Tan, Christina S Leslie, Thijs Beuming, Dinshaw J Patel, Yehuda Goldgur, John D Chodera, Michael Gregory Kharas
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nature communications 10 (1) (2019)
Lodoe Lama, Carolina Adura, Wei Xie, Daisuke Tomita, Taku Kamei, Vitaly Kuryavyi, Tasos Gogakos, Joshua I Steinberg, Michael Miller, Lavoisier Ramos-Espiritu, Yasutomi Asano, Shogo Hashizume, Jumpei Aida, Toshihiro Imaeda, Rei Okamoto, Andy J Jennings, Mayako Michino, Takanobu Kuroita, Andrew Stamford, Pu Gao, Peter Meinke, J Fraser Glickman, Dinshaw J Patel, Thomas Tuschl
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nature communications 10 (1) (2019)
Julia Batki, Jakob Schnabl, Juncheng Wang, Dominik Handler, Veselin I Andreev, Christian E Stieger, Maria Novatchkova, Lisa Lampersberger, Kotryna Kauneckaite, Wei Xie, Karl Mechtler, Dinshaw J Patel, Julius Brennecke
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. Nature structural & molecular biology 26 (8) (2019)