Osamu Nureki

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 103

Top Venues

Nature communications

Nature

Science (New York, N.Y.)

eLife

The University of Tokyo

The University of Tokyo (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Tokyo Apr 01 2008

Japan

Professor :: Department of Biological Sciences

Education History

The University of Tokyo Apr 01 1988 - Mar 31 1993

Japan

PHD :: Department of Biological Sciences

Publications

Yutaro Shuto, Ryoya Nakagawa, Shiyou Zhu, Mizuki Hoki, Satoshi N Omura, Hisato Hirano, Yuzuru Itoh, Feng Zhang, Osamu Nureki
Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature 631 (8019) (2024)
Yutaro Shuto, Ryoya Nakagawa, Shiyou Zhu, Mizuki Hoki, Satoshi N Omura, Hisato Hirano, Yuzuru Itoh, Feng Zhang, Osamu Nureki
Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature 631 (8019) (2024)
Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics. Nature communications 15 (1) (2024)
Takaaki A Kobayashi, Hiroto Shimada, Fumiya K Sano, Yuzuru Itoh, Sawako Enoki, Yasushi Okada, Tsukasa Kusakizako, Osamu Nureki
Dimeric transport mechanism of human vitamin C transporter SVCT1. Nature communications 15 (1) (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Shuhei Onishi, Kotone Uchiyama, Ko Sato, Chikako Okada, Shunsuke Kobayashi, Keisuke Hamada, Tomohiro Nishizawa, Osamu Nureki, Kazuhiro Ogata, Toru Sengoku
Structure of the human Bre1 complex bound to the nucleosome. Nature communications 15 (1) (2024)
Airi Jo-Watanabe, Toshiki Inaba, Takahiro Osada, Ryota Hashimoto, Tomohiro Nishizawa, Toshiaki Okuno, Sayoko Ihara, Kazushige Touhara, Nobutaka Hattori, Masatsugu Oh-Hora, Osamu Nureki, Takehiko Yokomizo
Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury. Nature communications 15 (1) (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Yutaro Shuto, Ryoya Nakagawa, Shiyou Zhu, Mizuki Hoki, Satoshi N Omura, Hisato Hirano, Yuzuru Itoh, Feng Zhang, Osamu Nureki
Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature 631 (8019) (2024)
Shuhei Onishi, Kotone Uchiyama, Ko Sato, Chikako Okada, Shunsuke Kobayashi, Keisuke Hamada, Tomohiro Nishizawa, Osamu Nureki, Kazuhiro Ogata, Toru Sengoku
Structure of the human Bre1 complex bound to the nucleosome. Nature communications 15 (1) (2024)
Yutaro Shuto, Ryoya Nakagawa, Shiyou Zhu, Mizuki Hoki, Satoshi N Omura, Hisato Hirano, Yuzuru Itoh, Feng Zhang, Osamu Nureki
Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature 631 (8019) (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Tamaki Izume, Ryo Kawahara, Akiharu Uwamizu, Luying Chen, Shun Yaginuma, Jumpei Omi, Hiroki Kawana, Fengjue Hou, Fumiya K Sano, Tatsuki Tanaka, Kazuhiro Kobayashi, Hiroyuki H Okamoto, Yoshiaki Kise, Tomohiko Ohwada, Junken Aoki, Wataru Shihoya, Osamu Nureki
Structural basis for lysophosphatidylserine recognition by GPR34. Nature communications 15 (1) (2024)
Shuhei Onishi, Kotone Uchiyama, Ko Sato, Chikako Okada, Shunsuke Kobayashi, Keisuke Hamada, Tomohiro Nishizawa, Osamu Nureki, Kazuhiro Ogata, Toru Sengoku
Structure of the human Bre1 complex bound to the nucleosome. Nature communications 15 (1) (2024)
Satoshi Watanabe, Yoshiaki Kise, Kento Yonezawa, Mariko Inoue, Nobutaka Shimizu, Osamu Nureki, Kenji Inaba
Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport. Nature communications 15 (1) (2024)
Aika Iwama, Ryoji Kise, Hiroaki Akasaka, Fumiya K Sano, Hidetaka S Oshima, Asuka Inoue, Wataru Shihoya, Osamu Nureki
Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103. Nature communications 15 (1) (2024)
Aika Iwama, Ryoji Kise, Hiroaki Akasaka, Fumiya K Sano, Hidetaka S Oshima, Asuka Inoue, Wataru Shihoya, Osamu Nureki
Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103. Nature communications 15 (1) (2024)
Toshihiro Nakane, Ryoya Nakagawa, Soh Ishiguro, Sae Okazaki, Hideto Mori, Yutaro Shuto, Keitaro Yamashita, Nozomu Yachie, Hiroshi Nishimasu, Osamu Nureki
Structure and engineering of Brevibacillus laterosporus Cas9. Communications biology 7 (1) (2024)
Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics. Nature communications 15 (1) (2024)
Tamaki Izume, Ryo Kawahara, Akiharu Uwamizu, Luying Chen, Shun Yaginuma, Jumpei Omi, Hiroki Kawana, Fengjue Hou, Fumiya K Sano, Tatsuki Tanaka, Kazuhiro Kobayashi, Hiroyuki H Okamoto, Yoshiaki Kise, Tomohiko Ohwada, Junken Aoki, Wataru Shihoya, Osamu Nureki
Structural basis for lysophosphatidylserine recognition by GPR34. Nature communications 15 (1) (2024)
Aika Iwama, Ryoji Kise, Hiroaki Akasaka, Fumiya K Sano, Hidetaka S Oshima, Asuka Inoue, Wataru Shihoya, Osamu Nureki
Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103. Nature communications 15 (1) (2024)
Hiroyuki H Okamoto, Erika Cecon, Osamu Nureki, Silvia Rivara, Ralf Jockers
Melatonin receptor structure and signaling. Journal of pineal research 76 (3) (2024)
Airi Jo-Watanabe, Toshiki Inaba, Takahiro Osada, Ryota Hashimoto, Tomohiro Nishizawa, Toshiaki Okuno, Sayoko Ihara, Kazushige Touhara, Nobutaka Hattori, Masatsugu Oh-Hora, Osamu Nureki, Takehiko Yokomizo
Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury. Nature communications 15 (1) (2024)
Aika Iwama, Ryoji Kise, Hiroaki Akasaka, Fumiya K Sano, Hidetaka S Oshima, Asuka Inoue, Wataru Shihoya, Osamu Nureki
Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103. Nature communications 15 (1) (2024)
Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics. Nature communications 15 (1) (2024)
Satoshi Watanabe, Yoshiaki Kise, Kento Yonezawa, Mariko Inoue, Nobutaka Shimizu, Osamu Nureki, Kenji Inaba
Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport. Nature communications 15 (1) (2024)
Takaaki A Kobayashi, Hiroto Shimada, Fumiya K Sano, Yuzuru Itoh, Sawako Enoki, Yasushi Okada, Tsukasa Kusakizako, Osamu Nureki
Dimeric transport mechanism of human vitamin C transporter SVCT1. Nature communications 15 (1) (2024)
Satoshi Watanabe, Yoshiaki Kise, Kento Yonezawa, Mariko Inoue, Nobutaka Shimizu, Osamu Nureki, Kenji Inaba
Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport. Nature communications 15 (1) (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Toshihiro Nakane, Ryoya Nakagawa, Soh Ishiguro, Sae Okazaki, Hideto Mori, Yutaro Shuto, Keitaro Yamashita, Nozomu Yachie, Hiroshi Nishimasu, Osamu Nureki
Structure and engineering of Brevibacillus laterosporus Cas9. Communications biology 7 (1) (2024)
Airi Jo-Watanabe, Toshiki Inaba, Takahiro Osada, Ryota Hashimoto, Tomohiro Nishizawa, Toshiaki Okuno, Sayoko Ihara, Kazushige Touhara, Nobutaka Hattori, Masatsugu Oh-Hora, Osamu Nureki, Takehiko Yokomizo
Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury. Nature communications 15 (1) (2024)
Yutaro Shuto, Ryoya Nakagawa, Shiyou Zhu, Mizuki Hoki, Satoshi N Omura, Hisato Hirano, Yuzuru Itoh, Feng Zhang, Osamu Nureki
Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature 631 (8019) (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Tamaki Izume, Ryo Kawahara, Akiharu Uwamizu, Luying Chen, Shun Yaginuma, Jumpei Omi, Hiroki Kawana, Fengjue Hou, Fumiya K Sano, Tatsuki Tanaka, Kazuhiro Kobayashi, Hiroyuki H Okamoto, Yoshiaki Kise, Tomohiko Ohwada, Junken Aoki, Wataru Shihoya, Osamu Nureki
Structural basis for lysophosphatidylserine recognition by GPR34. Nature communications 15 (1) (2024)
Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics. Nature communications 15 (1) (2024)
Toshihiro Nakane, Ryoya Nakagawa, Soh Ishiguro, Sae Okazaki, Hideto Mori, Yutaro Shuto, Keitaro Yamashita, Nozomu Yachie, Hiroshi Nishimasu, Osamu Nureki
Structure and engineering of Brevibacillus laterosporus Cas9. Communications biology 7 (1) (2024)
Takaaki A Kobayashi, Hiroto Shimada, Fumiya K Sano, Yuzuru Itoh, Sawako Enoki, Yasushi Okada, Tsukasa Kusakizako, Osamu Nureki
Dimeric transport mechanism of human vitamin C transporter SVCT1. Nature communications 15 (1) (2024)
Tamaki Izume, Ryo Kawahara, Akiharu Uwamizu, Luying Chen, Shun Yaginuma, Jumpei Omi, Hiroki Kawana, Fengjue Hou, Fumiya K Sano, Tatsuki Tanaka, Kazuhiro Kobayashi, Hiroyuki H Okamoto, Yoshiaki Kise, Tomohiko Ohwada, Junken Aoki, Wataru Shihoya, Osamu Nureki
Structural basis for lysophosphatidylserine recognition by GPR34. Nature communications 15 (1) (2024)
Yutaro Shuto, Ryoya Nakagawa, Shiyou Zhu, Mizuki Hoki, Satoshi N Omura, Hisato Hirano, Yuzuru Itoh, Feng Zhang, Osamu Nureki
Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature (2024)
Jagannath Maharana, Fumiya K Sano, Parishmita Sarma, Manish K Yadav, Longhan Duan, Tomasz Maciej Stepniewski, Madhu Chaturvedi, Ashutosh Ranjan, Vinay Singh, Sayantan Saha, Gargi Mahajan, Mohamed Chami, Wataru Shihoya, Jana Selent, Ka Young Chung, Ramanuj Banerjee, Osamu Nureki, Arun K Shukla
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.) 383 (6678) (2024)
Takaaki A Kobayashi, Hiroto Shimada, Fumiya K Sano, Yuzuru Itoh, Sawako Enoki, Yasushi Okada, Tsukasa Kusakizako, Osamu Nureki
Dimeric transport mechanism of human vitamin C transporter SVCT1. Nature communications 15 (1) (2024)
Ariel Chazan, Ishita Das, Takayoshi Fujiwara, Shunya Murakoshi, Andrey Rozenberg, Ana Molina-Márquez, Fumiya K Sano, Tatsuki Tanaka, Patricia Gómez-Villegas, Shirley Larom, Alina Pushkarev, Partha Malakar, Masumi Hasegawa, Yuya Tsukamoto, Tomohiro Ishizuka, Masae Konno, Takashi Nagata, Yosuke Mizuno, Kota Katayama, Rei Abe-Yoshizumi, Sanford Ruhman, Keiichi Inoue, Hideki Kandori, Rosa León, Wataru Shihoya, Susumu Yoshizawa, Mordechai Sheves, Osamu Nureki, Oded Béjà
Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature 615 (7952) (2023)
Ariel Chazan, Ishita Das, Takayoshi Fujiwara, Shunya Murakoshi, Andrey Rozenberg, Ana Molina-Márquez, Fumiya K Sano, Tatsuki Tanaka, Patricia Gómez-Villegas, Shirley Larom, Alina Pushkarev, Partha Malakar, Masumi Hasegawa, Yuya Tsukamoto, Tomohiro Ishizuka, Masae Konno, Takashi Nagata, Yosuke Mizuno, Kota Katayama, Rei Abe-Yoshizumi, Sanford Ruhman, Keiichi Inoue, Hideki Kandori, Rosa León, Wataru Shihoya, Susumu Yoshizawa, Mordechai Sheves, Osamu Nureki, Oded Béjà
Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature 615 (7952) (2023)
Fumiya K Sano, Hiroaki Akasaka, Wataru Shihoya, Osamu Nureki
Cryo-EM structure of the endothelin-1-ET B -G i complex. eLife 12 (2023)
Takafumi Hiramoto, Yuji Kashiwakura, Morisada Hayakawa, Nemekhbayar Baatartsogt, Nobuhiko Kamoshita, Tomoyuki Abe, Hiroshi Inaba, Hiroshi Nishimasu, Hideki Uosaki, Yutaka Hanazono, Osamu Nureki, Tsukasa Ohmori
PAM-flexible Cas9-mediated base editing of a hemophilia B mutation in induced pluripotent stem cells. Communications medicine 3 (1) (2023)
Fumiya K Sano, Hiroaki Akasaka, Wataru Shihoya, Osamu Nureki
Cryo-EM structure of the endothelin-1-ET B -G i complex. eLife 12 (2023)
Satoshi N Omura, Ryoya Nakagawa, Christian Südfeld, Ricardo Villegas Warren, Wen Y Wu, Hisato Hirano, Charlie Laffeber, Tsukasa Kusakizako, Yoshiaki Kise, Joyce H G Lebbink, Yuzuru Itoh, John van der Oost, Osamu Nureki
Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme. Nature structural & molecular biology (2023)
Ryoya Nakagawa, Hisato Hirano, Satoshi N Omura, Suchita P Nety, Soumya Kannan, Han Altae-Tran, Xiao Yao, Yuriko Sakaguchi, Takayuki Ohira, Wen Y Wu, Hiroshi Nakayama, Yutaro Shuto, Tatsuki Tanaka, Fumiya K Sano, Tsukasa Kusakizako, Yoshiaki Kise, Yuzuru Itoh, Naoshi Dohmae, John van der Oost, Tsutomu Suzuki, Feng Zhang, Osamu Nureki
Cryo-EM structure of the transposon-associated TnpB enzyme. Nature (2023)
Takafumi Hiramoto, Hiroshi Inaba, Nemekhbayar Baatartsogt, Yuji Kashiwakura, Morisada Hayakawa, Nobuhiko Kamoshita, Hiroshi Nishimasu, Osamu Nureki, Ei Kinai, Tsukasa Ohmori
Genome editing of patient-derived iPSCs identifies a deep intronic variant causing aberrant splicing in hemophilia A. Blood advances (2023)
Ariel Chazan, Ishita Das, Takayoshi Fujiwara, Shunya Murakoshi, Andrey Rozenberg, Ana Molina-Márquez, Fumiya K Sano, Tatsuki Tanaka, Patricia Gómez-Villegas, Shirley Larom, Alina Pushkarev, Partha Malakar, Masumi Hasegawa, Yuya Tsukamoto, Tomohiro Ishizuka, Masae Konno, Takashi Nagata, Yosuke Mizuno, Kota Katayama, Rei Abe-Yoshizumi, Sanford Ruhman, Keiichi Inoue, Hideki Kandori, Rosa León, Wataru Shihoya, Susumu Yoshizawa, Mordechai Sheves, Osamu Nureki, Oded Béjà
Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature 615 (7952) (2023)
Kazuhiro Kobayashi, Kouki Kawakami, Tsukasa Kusakizako, Atsuhiro Tomita, Michihiro Nishimura, Kazuhiro Sawada, Hiroyuki H Okamoto, Suzune Hiratsuka, Gaku Nakamura, Riku Kuwabara, Hiroshi Noda, Hiroyasu Muramatsu, Masaru Shimizu, Tomohiko Taguchi, Asuka Inoue, Takeshi Murata, Osamu Nureki
Class B1 GPCR activation by an intracellular agonist. Nature (2023)
Ariel Chazan, Ishita Das, Takayoshi Fujiwara, Shunya Murakoshi, Andrey Rozenberg, Ana Molina-Márquez, Fumiya K Sano, Tatsuki Tanaka, Patricia Gómez-Villegas, Shirley Larom, Alina Pushkarev, Partha Malakar, Masumi Hasegawa, Yuya Tsukamoto, Tomohiro Ishizuka, Masae Konno, Takashi Nagata, Yosuke Mizuno, Kota Katayama, Rei Abe-Yoshizumi, Sanford Ruhman, Keiichi Inoue, Hideki Kandori, Rosa León, Wataru Shihoya, Susumu Yoshizawa, Mordechai Sheves, Osamu Nureki, Oded Béjà
Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature (2023)
Fumiya K Sano, Hiroaki Akasaka, Wataru Shihoya, Osamu Nureki
Cryo-EM structure of the endothelin-1-ET B -G i complex. eLife 12 (2023)
Fumiya K Sano, Hiroaki Akasaka, Wataru Shihoya, Osamu Nureki
Cryo-EM structure of the endothelin-1-ET B -G i complex. eLife 12 (2023)
Cecilia Safari, Swagatha Ghosh, Rebecka Andersson, Jonatan Johannesson, Petra Båth, Owens Uwangue, Peter Dahl, Doris Zorić, Emil Sandelin, Adams Vallejos, Eriko Nango, Rie Tanaka, Robert Bosman, Per Börjesson, Elin Dunevall, Greger Hammarin, Giorgia Ortolani, Matthijs R Panman, Tomoyuki Tanaka, Ayumi Yamashita, Toshi Arima, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Hanae Takeda, Raika Yamagiwa, Kazumasa Oda, Masahiro Fukuda, Takehiko Tosha, Hisashi Naitow, Shigeki Owada, Kensure Tono, Osamu Nureki, So Iwata, Richard Neutze, Gisela Brändén
Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Science advances 9 (49) (2023)
Fumiya K Sano, Hiroaki Akasaka, Wataru Shihoya, Osamu Nureki
Cryo-EM structure of the endothelin-1-ET B -G i complex. eLife 12 (2023)
Fumiya K Sano, Hiroaki Akasaka, Wataru Shihoya, Osamu Nureki
Cryo-EM structure of the endothelin-1-ET B -G i complex. eLife 12 (2023)
Masahiro Hiraizumi, Tomoya Akashi, Kouta Murasaki, Hiroyuki Kishida, Taichi Kumanomidou, Nao Torimoto, Osamu Nureki, Ikuko Miyaguchi
Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nature structural & molecular biology (2023)
Hiroaki Akasaka, Tatsuki Tanaka, Fumiya K Sano, Yuma Matsuzaki, Wataru Shihoya, Osamu Nureki
Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nature communications 13 (1) (2022)
Takafumi Kato, Tsukasa Kusakizako, Chunhuan Jin, Xinyu Zhou, Ryuichi Ohgaki, LiLi Quan, Minhui Xu, Suguru Okuda, Kan Kobayashi, Keitaro Yamashita, Tomohiro Nishizawa, Yoshikatsu Kanai, Osamu Nureki
Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2. Nature communications 13 (1) (2022)
Haon Futamata, Masahiro Fukuda, Rie Umeda, Keitaro Yamashita, Atsuhiro Tomita, Satoe Takahashi, Takafumi Shikakura, Shigehiko Hayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazuaki Homma, Osamu Nureki
Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature communications 13 (1) (2022)
Haon Futamata, Masahiro Fukuda, Rie Umeda, Keitaro Yamashita, Atsuhiro Tomita, Satoe Takahashi, Takafumi Shikakura, Shigehiko Hayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazuaki Homma, Osamu Nureki
Author Correction: Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nature communications 13 (1) (2022)
Sonomi Yamaguchi, Masahiro Naganuma, Tomohiro Nishizawa, Tsukasa Kusakizako, Yukihide Tomari, Hiroshi Nishimasu, Osamu Nureki
Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature 607 (7918) (2022)
Ryoya Nakagawa, Soh Ishiguro, Sae Okazaki, Hideto Mori, Mamoru Tanaka, Hiroyuki Aburatani, Nozomu Yachie, Hiroshi Nishimasu, Osamu Nureki
Engineered Campylobacter jejuni Cas9 variant with enhanced activity and broader targeting range. Communications biology 5 (1) (2022)
Tatsuya Hagino, Takafumi Kato, Go Kasuya, Kan Kobayashi, Tsukasa Kusakizako, Shin Hamamoto, Tomoaki Sobajima, Yuichiro Fujiwara, Keitaro Yamashita, Hisashi Kawasaki, Andrés D Maturana, Tomohiro Nishizawa, Osamu Nureki
Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1. Nature communications 13 (1) (2022)
Toshiaki Hosaka, Takashi Nomura, Minoru Kubo, Takanori Nakane, Luo Fangjia, Shun-Ichi Sekine, Takuhiro Ito, Kazutaka Murayama, Kentaro Ihara, Haruhiko Ehara, Kazuhiro Kashiwagi, Kazushige Katsura, Ryogo Akasaka, Tamao Hisano, Tomoyuki Tanaka, Rie Tanaka, Toshi Arima, Ayumi Yamashita, Michihiro Sugahara, Hisashi Naitow, Yoshinori Matsuura, Susumu Yoshizawa, Kensure Tono, Shigeki Owada, Osamu Nureki, Tomomi Kimura-Someya, So Iwata, Eriko Nango, Mikako Shirouzu
Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers. Proceedings of the National Academy of Sciences of the United States of America 119 (9) (2022)
Hajime Shinoda, Tatsuya Iida, Asami Makino, Mami Yoshimura, Junichiro Ishikawa, Jun Ando, Kazue Murai, Katsumi Sugiyama, Yukiko Muramoto, Masahiro Nakano, Kotaro Kiga, Longzhu Cui, Osamu Nureki, Hiroaki Takeuchi, Takeshi Noda, Hiroshi Nishimasu, Rikiya Watanabe
Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis. Communications biology 5 (1) (2022)
Yuki Imaizumi, Kazunori Takanuki, Takuya Miyake, Mizuki Takemoto, Kunio Hirata, Mika Hirose, Rika Oi, Tatsuya Kobayashi, Kenichi Miyoshi, Rie Aruga, Tatsuhiko Yokoyama, Shizuka Katagiri, Hiroaki Matsuura, Kenji Iwasaki, Takayuki Kato, Mika K Kaneko, Yukinari Kato, Michiko Tajiri, Satoko Akashi, Osamu Nureki, Yohei Hizukuri, Yoshinori Akiyama, Terukazu Nogi
Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Science advances 8 (34) (2022)
Hajime Shinoda, Yuya Taguchi, Ryoya Nakagawa, Asami Makino, Sae Okazaki, Masahiro Nakano, Yukiko Muramoto, Chiharu Takahashi, Ikuko Takahashi, Jun Ando, Takeshi Noda, Osamu Nureki, Hiroshi Nishimasu, Rikiya Watanabe
Amplification-free RNA detection with CRISPR-Cas13. Communications biology 4 (1) (2021)
Hiroyuki H Okamoto, Hirotake Miyauchi, Asuka Inoue, Francesco Raimondi, Hirokazu Tsujimoto, Tsukasa Kusakizako, Wataru Shihoya, Keitaro Yamashita, Ryoji Suno, Norimichi Nomura, Takuya Kobayashi, So Iwata, Tomohiro Nishizawa, Osamu Nureki
Cryo-EM structure of the human MT1-Gi signaling complex. Nature structural & molecular biology 28 (8) (2021)
Hisato Iriki, Hayato Takahashi, Naoko Wada, Hisashi Nomura, Miho Mukai, Aki Kamata, Hiromi Ito, Jun Yamagami, Takeshi Matsui, Yutaka Kurebayashi, Setsuko Mise-Omata, Hiroshi Nishimasu, Osamu Nureki, Akihiko Yoshimura, Shohei Hori, Masayuki Amagai
Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus. Proceedings of the National Academy of Sciences of the United States of America 118 (49) (2021)
Ko Sato, Amarjeet Kumar, Keisuke Hamada, Chikako Okada, Asako Oguni, Ayumi Machiyama, Shun Sakuraba, Tomohiro Nishizawa, Osamu Nureki, Hidetoshi Kono, Kazuhiro Ogata, Toru Sengoku
Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2. Nature communications 12 (1) (2021)
Akimitsu Higuchi, Wataru Shihoya, Masae Konno, Tatsuya Ikuta, Hideki Kandori, Keiichi Inoue, Osamu Nureki
Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping. Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Yoshiaki Kise, Go Kasuya, Hiroyuki H Okamoto, Daichi Yamanouchi, Kan Kobayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, Koichi Nakajo, Osamu Nureki
Structural basis of gating modulation of Kv4 channel complexes. Nature 599 (7883) (2021)
Kazumasa Oda, Takashi Nomura, Takanori Nakane, Keitaro Yamashita, Keiichi Inoue, Shota Ito, Johannes Vierock, Kunio Hirata, Andrés D Maturana, Kota Katayama, Tatsuya Ikuta, Itsuki Ishigami, Tamaki Izume, Rie Umeda, Ryuun Eguma, Satomi Oishi, Go Kasuya, Takafumi Kato, Tsukasa Kusakizako, Wataru Shihoya, Hiroto Shimada, Tomoyuki Takatsuji, Mizuki Takemoto, Reiya Taniguchi, Atsuhiro Tomita, Ryoki Nakamura, Masahiro Fukuda, Hirotake Miyauchi, Yongchan Lee, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Michihiro Sugahara, Tetsunari Kimura, Tatsuro Shimamura, Takaaki Fujiwara, Yasuaki Yamanaka, Shigeki Owada, Yasumasa Joti, Kensuke Tono, Ryuichiro Ishitani, Shigehiko Hayashi, Hideki Kandori, Peter Hegemann, So Iwata, Minoru Kubo, Tomohiro Nishizawa, Osamu Nureki
Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin. eLife 10 (2021)
Ludovic Enkler, Bruno Rinaldi, Johan-Owen De Craene, Philippe Hammann, Osamu Nureki, Bruno Senger, Sylvie Friant, Hubert Dominique Becker
Cex1 is a component of the COPI intracellular trafficking machinery. Biology open 10 (3) (2021)
Kazumasa Oda, Yongchan Lee, Pattama Wiriyasermkul, Yoko Tanaka, Mizuki Takemoto, Keitaro Yamashita, Shushi Nagamori, Tomohiro Nishizawa, Osamu Nureki
Consensus mutagenesis approach improves the thermal stability of system xc - transporter, xCT, and enables cryo-EM analyses. Protein science : a publication of the Protein Society 29 (12) (2020)
Kazuhiro Kobayashi, Wataru Shihoya, Tomohiro Nishizawa, Francois Marie Ngako Kadji, Junken Aoki, Asuka Inoue, Osamu Nureki
Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nature structural & molecular biology 27 (3) (2020)
Tatsuya Ikuta, Wataru Shihoya, Masahiro Sugiura, Kazuho Yoshida, Masahito Watari, Takaya Tokano, Keitaro Yamashita, Kota Katayama, Satoshi P Tsunoda, Takayuki Uchihashi, Hideki Kandori, Osamu Nureki
Structural insights into the mechanism of rhodopsin phosphodiesterase. Nature communications 11 (1) (2020)
Sonomi Yamaguchi, Akira Oe, Kazumichi M Nishida, Keitaro Yamashita, Asako Kajiya, Seiichi Hirano, Naoki Matsumoto, Naoshi Dohmae, Ryuichiro Ishitani, Kuniaki Saito, Haruhiko Siomi, Hiroshi Nishimasu, Mikiko C Siomi, Osamu Nureki
Crystal structure of Drosophila Piwi. Nature communications 11 (1) (2020)
Rina C Sakata, Soh Ishiguro, Hideto Mori, Mamoru Tanaka, Kenji Tatsuno, Hiroki Ueda, Shogo Yamamoto, Motoaki Seki, Nanami Masuyama, Keiji Nishida, Hiroshi Nishimasu, Kazuharu Arakawa, Akihiko Kondo, Osamu Nureki, Masaru Tomita, Hiroyuki Aburatani, Nozomu Yachie
Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Nature biotechnology 38 (7) (2020)
Akiyuki Taruno, Kengo Nomura, Tsukasa Kusakizako, Zhongming Ma, Osamu Nureki, J Kevin Foskett
Taste transduction and channel synapses in taste buds. Pflugers Archiv : European journal of physiology 473 (1) (2020)
Kanae Demura, Tsukasa Kusakizako, Wataru Shihoya, Masahiro Hiraizumi, Kengo Nomura, Hiroto Shimada, Keitaro Yamashita, Tomohiro Nishizawa, Akiyuki Taruno, Osamu Nureki
Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Science advances 6 (29) (2020)
Hiroto Shimada, Tsukasa Kusakizako, T H Dung Nguyen, Tomohiro Nishizawa, Tomoya Hino, Makoto Tominaga, Osamu Nureki
The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism. Nature structural & molecular biology 27 (7) (2020)
Rie Umeda, Yuhkoh Satouh, Mizuki Takemoto, Yoshiko Nakada-Nakura, Kehong Liu, Takeshi Yokoyama, Mikako Shirouzu, So Iwata, Norimichi Nomura, Ken Sato, Masahito Ikawa, Tomohiro Nishizawa, Osamu Nureki
Structural insights into tetraspanin CD9 function. Nature communications 11 (1) (2020)
Ryoki Nakamura, Tomohiro Numata, Go Kasuya, Takeshi Yokoyama, Tomohiro Nishizawa, Tsukasa Kusakizako, Takafumi Kato, Tatsuya Hagino, Naoshi Dohmae, Masato Inoue, Kengo Watanabe, Hidenori Ichijo, Masahide Kikkawa, Mikako Shirouzu, Thomas J Jentsch, Ryuichiro Ishitani, Yasunobu Okada, Osamu Nureki
Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation. Communications biology 3 (1) (2020)
Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin, Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazumasa Oda, Ryuichiro Ishitani, Takeshi Yokoyama, Takanori Nakane, Mikako Shirouzu, Hitoshi Endou, Shushi Nagamori, Yoshikatsu Kanai, Osamu Nureki
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nature structural & molecular biology 26 (6) (2019)
Takafumi Kato, Kaoru Kumazaki, Miki Wada, Reiya Taniguchi, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Ryuichiro Ishitani, Koichi Ito, Tomohiro Nishizawa, Osamu Nureki
Crystal structure of plant vacuolar iron transporter VIT1. Nature plants 5 (3) (2019)
Masahiro Hiraizumi, Keitaro Yamashita, Tomohiro Nishizawa, Osamu Nureki
Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science (New York, N.Y.) 365 (6458) (2019)
Seiichi Hirano, Omar O Abudayyeh, Jonathan S Gootenberg, Takuro Horii, Ryuichiro Ishitani, Izuho Hatada, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki
Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. Nature communications 10 (1) (2019)
Reina Nagamura, Masahiro Fukuda, Akihiro Kawamoto, Kyoko Matoba, Naoshi Dohmae, Ryuichiro Ishitani, Junichi Takagi, Osamu Nureki
Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2. Acta crystallographica. Section F, Structural biology communications 75 (Pt 5) (2019)
Chisae Nagiri, Wataru Shihoya, Asuka Inoue, Francois Marie Ngako Kadji, Junken Aoki, Osamu Nureki
Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500. Communications biology 2 (2019)
Shinichiro Akichika, Seiichi Hirano, Yuichi Shichino, Takeo Suzuki, Hiroshi Nishimasu, Ryuichiro Ishitani, Ai Sugita, Yutaka Hirose, Shintaro Iwasaki, Osamu Nureki, Tsutomu Suzuki
Cap-specific terminal N 6-methylation of RNA by an RNA polymerase II-associated methyltransferase. Science (New York, N.Y.) 363 (6423) (2018)
Takeshi Yamamoto, Yusuke Endo, Atsushi Onodera, Kiyoshi Hirahara, Hikari K Asou, Takahiro Nakajima, Toshio Kanno, Yasuo Ouchi, Satoshi Uematsu, Hiroshi Nishimasu, Osamu Nureki, Damon J Tumes, Naoki Shimojo, Toshinori Nakayama
DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nature communications 9 (1) (2018)
Wataru Shihoya, Tamaki Izume, Asuka Inoue, Keitaro Yamashita, Francois Marie Ngako Kadji, Kunio Hirata, Junken Aoki, Tomohiro Nishizawa, Osamu Nureki
Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation. Nature communications 9 (1) (2018)
Saki Osuka, Kazushi Isomura, Shohei Kajimoto, Tomotaka Komori, Hiroshi Nishimasu, Tomohiro Shima, Osamu Nureki, Sotaro Uemura
Real-time observation of flexible domain movements in CRISPR-Cas9. The EMBO journal 37 (10) (2018)
Tatsuro Maruyama, Shunsuke Imai, Tsukasa Kusakizako, Motoyuki Hattori, Ryuichiro Ishitani, Osamu Nureki, Koichi Ito, Andrès D Maturana, Ichio Shimada, Masanori Osawa
Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR. eLife 7 (2018)
Kazuki Kato, Hiroshi Nishimasu, Daisuke Oikawa, Seiichi Hirano, Hisato Hirano, Go Kasuya, Ryuichiro Ishitani, Fuminori Tokunaga, Osamu Nureki
Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1. Nature communications 9 (1) (2018)
Kazumasa Oda, Johannes Vierock, Satomi Oishi, Silvia Rodriguez-Rozada, Reiya Taniguchi, Keitaro Yamashita, J Simon Wiegert, Tomohiro Nishizawa, Peter Hegemann, Osamu Nureki
Crystal structure of the red light-activated channelrhodopsin Chrimson. Nature communications 9 (1) (2018)

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Osamu Nureki