Michael C Thompson (Michael Thompson)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Topics

Molecular Dynamics Simulations

High Resolution

Respiratory Syndrome Coronavirus

Angiotensin Converting Enzyme

Top Venues

Science advances

Science (New York, N.Y.)

bioRxiv : the preprint server for biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E Cohen, Sébastien Boutet, Mark S Hunter, Christopher Kupitz, Frédéric P Poitevin, Frank R Moss, David W Mittan-Moreau, Aaron S Brewster, Nicholas K Sauter, Iris D Young, Alexander M Wolff, Virendra K Tiwari, Nivesh Kumar, David B Berkowitz, Ryan G Hadt, Michael C Thompson, Alec H Follmer, Michael E Wall, Mark A Wilson
Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Science advances 10 (13) (2024)
Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E Cohen, Sébastien Boutet, Mark S Hunter, Christopher Kupitz, Frédéric P Poitevin, Frank R Moss, David W Mittan-Moreau, Aaron S Brewster, Nicholas K Sauter, Iris D Young, Alexander M Wolff, Virendra K Tiwari, Nivesh Kumar, David B Berkowitz, Ryan G Hadt, Michael C Thompson, Alec H Follmer, Michael E Wall, Mark A Wilson
Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Science advances 10 (13) (2024)
Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E Cohen, Sébastien Boutet, Mark S Hunter, Christopher Kupitz, Frédéric P Poitevin, Frank R Moss, David W Mittan-Moreau, Aaron S Brewster, Nicholas K Sauter, Iris D Young, Alexander M Wolff, Virendra K Tiwari, Nivesh Kumar, David B Berkowitz, Ryan G Hadt, Michael C Thompson, Alec H Follmer, Michael E Wall, Mark A Wilson
Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Science advances 10 (13) (2024)
Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E Cohen, Sébastien Boutet, Mark S Hunter, Christopher Kupitz, Frédéric P Poitevin, Frank R Moss, David W Mittan-Moreau, Aaron S Brewster, Nicholas K Sauter, Iris D Young, Alexander M Wolff, Virendra K Tiwari, Nivesh Kumar, David B Berkowitz, Ryan G Hadt, Michael C Thompson, Alec H Follmer, Michael E Wall, Mark A Wilson
Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Science advances 10 (13) (2024)
Nathan Smith, Medhanjali Dasgupta, David C Wych, Cole Dolamore, Raymond G Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E Cohen, Sébastien Boutet, Mark S Hunter, Christopher Kupitz, Frédéric P Poitevin, Frank R Moss, David W Mittan-Moreau, Aaron S Brewster, Nicholas K Sauter, Iris D Young, Alexander M Wolff, Virendra K Tiwari, Nivesh Kumar, David B Berkowitz, Ryan G Hadt, Michael C Thompson, Alec H Follmer, Michael E Wall, Mark A Wilson
Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Science advances 10 (13) (2024)
Antony D St-Jacques, Joshua M Rodriguez, Matthew G Eason, Scott M Foster, Safwat T Khan, Adam M Damry, Natalie K Goto, Michael C Thompson, Roberto A Chica
Computational remodeling of an enzyme conformational landscape for altered substrate selectivity. Nature communications 14 (1) (2023)
Rakotoharisoa Rojo, Behnoush Seifinoferest, Niayesh Zarifi, Jack D M Miller, Joshua M Rodriguez, Michael C Thompson, Roberto A Chica
Design of efficient artificial enzymes using crystallographically-enhanced conformational sampling. bioRxiv : the preprint server for biology (2023)
Alexander M Wolff, Eriko Nango, Iris D Young, Aaron S Brewster, Minoru Kubo, Takashi Nomura, Michihiro Sugahara, Shigeki Owada, Benjamin A Barad, Kazutaka Ito, Asmit Bhowmick, Sergio Carbajo, Tomoya Hino, James M Holton, Dohyun Im, Lee J O'Riordan, Tomoyuki Tanaka, Rie Tanaka, Raymond G Sierra, Fumiaki Yumoto, Kensure Tono, So Iwata, Nicholas K Sauter, Brian K Shoichet, Michael C Thompson
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography. Nature chemistry (2023)
Nathan Smith, Medhanjali Dasgupta, David C Wych, Coleman Dolamore, Raymond G Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E Cohen, Sébastien Boutet, Mark S Hunter, Christopher Kupitz, Frédéric P Poitevin, Frank R Moss, Aaron S Brewster, Nicholas K Sauter, Iris D Young, Alexander M Wolff, Virendra K Tiwari, Nivesh Kumar, David B Berkowitz, Ryan G Hadt, Michael C Thompson, Alec H Follmer, Michael E Wall, Mark A Wilson
Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography. bioRxiv : the preprint server for biology (2023)
Roberto Efraín Díaz, Andrew K Ecker, Galen J Correy, Pooja Asthana, Iris D Young, Bryan Faust, Michael C Thompson, Ian B Seiple, Steven J Van Dyken, Richard M Locksley, Brian K Shoichet
Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase. bioRxiv : the preprint server for biology (2023)
Galen J Correy, Daniel W Kneller, Gwyndalyn Phillips, Swati Pant, Silvia Russi, Aina E Cohen, George Meigs, James M Holton, Stefan Gahbauer, Michael C Thompson, Alan Ashworth, Leighton Coates, Andrey Y Kovalevsky, Flora Meilleur, Brian K Shoichet
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature. Science advances 8 (21) (2022)
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Roberto Efraín Díaz, Iris D Young, Luan Carvalho Martins, Dominique H Smith, Ursula Schulze-Gahmen, Tristan W Owens, Ishan Deshpande, Gregory E Merz, Aye C Thwin, Justin T Biel, Jessica K Peters, Michelle Moritz, Nadia Herrera, Huong T Kratochvil, null null, Anthony Aimon, James M Bennett, José Brandão-Neto, Aina E Cohen, Alexandre Dias, Alice Douangamath, Louise Dunnett, Oleg Fedorov, Matteo P Ferla, Martin R Fuchs, Tyler J Gorrie-Stone, James M Holton, Michael G Johnson, Tobias Krojer, George Meigs, Ailsa J Powell, Johannes Gregor Matthias Rack, Victor L Rangel, Silvia Russi, Rachael E Skyner, Clyde A Smith, Alexei S Soares, Jennifer L Wierman, Kang Zhu, Peter O'Brien, Natalia Jura, Alan Ashworth, John J Irwin, Michael C Thompson, Jason E Gestwicki, Frank von Delft, Brian K Shoichet, Brian K Shoichet, Ivan Ahel
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Science advances 7 (16) (2021)
Michael Schoof, Bryan Faust, Reuben A Saunders, Smriti Sangwan, Veronica V Rezelj, Nicholas Hoppe, Morgane Boone, Christian B Billesbølle, Cristina Puchades, Caleigh M Azumaya, Huong T Kratochvil, Marcell Zimanyi, Ishan Deshpande, Jiahao Liang, Miles Sasha Dickinson, Henry C Nguyen, Cynthia M Chio, Gregory E Merz, Michael C Thompson, Devan Diwanji, Kaitlin Schaefer, Aditya A Anand, Niv Dobzinski, Beth Shoshanna Zha, Camille R Simoneau, Kristoffer E Leon, Kris M White, Un Seng Chio, Meghna Gupta, Mingliang Jin, Fei Li, Yanxin Liu, Kaihua Zhang, David Bulkley, Ming Sun, Amber M Smith, Alexandrea N Rizo, Frank R Moss, Axel F Brilot, Sergei Pourmal, Raphael Trenker, Thomas H Pospiech, Sayan Gupta, Benjamin Barsi-Rhyne, Vladislav Belyy, Andrew W Barile-Hill, Silke Nock, Yuwei Liu, Nevan J Krogan, Corie Y Ralston, Danielle L Swaney, Adolfo García-Sastre, Melanie M Ott, Marco Vignuzzi, null null, Peter Walter, Aashish Manglik
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science (New York, N.Y.) 370 (6523) (2020)
Anum Azam Glasgow, Yao-Ming Huang, Daniel J Mandell, Michael C Thompson, Ryan Ritterson, Amanda L Loshbaugh, Jenna Pellegrino, Cody Krivacic, Roland A Pache, Kyle A Barlow, Noah Ollikainen, Deborah Jeon, Mark J S Kelly, Brian K Shoichet, Tanja Kortemme
Computational design of a modular protein sense-response system. Science (New York, N.Y.) 366 (6468) (2020)
Xingjie Pan, Michael C Thompson, Sunny Zhang, Lin Liu, Brian K Shoichet, Mark J S Kelly, Tanja Kortemme
Expanding the space of protein geometries by computational design of de novo fold families. Science (New York, N.Y.) 369 (6507) (2020)
Alexander M Wolff, Iris D Young, Raymond G Sierra, Aaron S Brewster, Michael W Martynowycz, Eriko Nango, Michihiro Sugahara, Takanori Nakane, Kazutaka Ito, Andrew Aquila, Asmit Bhowmick, Justin T Biel, Sergio Carbajo, Aina E Cohen, Saul Cortez, Ana Gonzalez, Tomoya Hino, Dohyun Im, Jake D Koralek, Minoru Kubo, Tomas S Lazarou, Takashi Nomura, Shigeki Owada, Avi J Samelson, Tomoyuki Tanaka, Rie Tanaka, Erin M Thompson, Henry van den Bedem, Rahel A Woldeyes, Fumiaki Yumoto, Wei Zhao, Kensure Tono, Sébastien Boutet, So Iwata, Tamir Gonen, Nicholas K Sauter, Brian K Shoichet, Michael C Thompson
Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals. IUCrJ 7 (Pt 2) (2020)
Aron Broom, Rojo V Rakotoharisoa, Michael C Thompson, Niayesh Zarifi, Erin Nguyen, Nurzhan Mukhametzhanov, Lin Liu, Brian K Shoichet, Roberto A Chica
Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nature communications 11 (1) (2020)
Michael C Thompson, Duilio Cascio, Todd O Yeates
Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta crystallographica. Section D, Structural biology 74 (Pt 5) (2018)