Mark S P Sansom (Mark Sp Sansom, Mark Sansom)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 60

Top Topics

Single Molecule

Molecular Dynamics Simulations

Top Venues

Nature communications

Journal of chemical theory and computation

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

T Bertie Ansell, Wanling Song, Claire E Coupland, Loic Carrique, Robin Adam Corey, Anna L Duncan, C Keith Cassidy, Maxwell M G Geurts, Tim Rasmussen, Andrew B Ward, Christian Siebold, Phillip J Stansfeld, Mark S P Sansom
LipIDens: simulation assisted interpretation of lipid densities in cryo-EM structures of membrane proteins. Nature communications 14 (1) (2023)
T Bertie Ansell, Robin A Corey, Lucrezia Vittoria Viti, Maia Kinnebrew, Rajat Rohatgi, Christian Siebold, Mark S P Sansom
The Energetics and Ion Coupling of Cholesterol Transport Through Patched1. bioRxiv : the preprint server for biology (2023)
Tillson Bertie Ansell, Robin Adam Corey, Lucrezia Vittoria Viti, Maia Kinnebrew, Rajat Rohatgi, Christian Siebold, Mark S P Sansom
The energetics and ion coupling of cholesterol transport through Patched1. Science advances 9 (34) (2023)
Linda X Phan, Aaron P Owji, Tingting Yang, Jason Crain, Mark S P Sansom, Stephen J Tucker
Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl - Channel. bioRxiv : the preprint server for biology (2023)
Ken Sakamoto, Takuma Akimoto, Mayu Muramatsu, Mark S P Sansom, Ralf Metzler, Eiji Yamamoto
Heterogeneous biological membranes regulate protein partitioning via fluctuating diffusivity. PNAS nexus 2 (8) (2023)
T Bertie Ansell, Robin A Corey, Lucrezia Vittoria Viti, Maia Kinnebrew, Rajat Rohatgi, Christian Siebold, Mark S P Sansom
The Energetics and Ion Coupling of Cholesterol Transport Through Patched1. bioRxiv : the preprint server for biology (2023)
Hsin-Yung Yen, Idlir Liko, Wanling Song, Parth Kapoor, Fernando Almeida, Joanna Toporowska, Karolina Gherbi, Jonathan T S Hopper, Steven J Charlton, Argyris Politis, Mark S P Sansom, Ali Jazayeri, Carol V Robinson
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor. Nature chemistry (2022)
Yao Meng, Sami Sanlidag, Sacha A Jensen, Sean A Burnap, Weston B Struwe, Andreas Haahr Larsen, Xinyi Feng, Shruti Mittal, Mark S P Sansom, Cecilia Sahlgren, Penny A Handford
An N-glycan on the C2 domain of JAGGED1 is important for Notch activation. Science signaling 15 (755) (2022)
Arvind Kumar, Kayla Kindig, Shanlin Rao, Afroditi-Maria Zaki, Sandip Basak, Mark S P Sansom, Philip Charles Biggin, Sudha Chakrapani
Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs. Nature communications 13 (1) (2022)
Robin Adam Corey, Noah Harrison, Philllp J Stansfeld, Mark S P Sansom, Anna L Duncan
Cardiolipin, and not monolysocardiolipin, preferentially binds to the interface of complexes III and IV. Chemical science 13 (45) (2022)
Wanling Song, Robin Adam Corey, Tillson Bertie Ansell, C Keith Cassidy, Michael R Horrell, Anna L Duncan, Phillip J Stansfeld, Mark S P Sansom
PyLipID: A Python Package for Analysis of Protein-Lipid Interactions from Molecular Dynamics Simulations. Journal of chemical theory and computation 18 (2) (2022)
Nicolai Tidemand Johansen, Marta Bonaccorsi, Tone Bengtsen, Andreas Haahr Larsen, Frederik Grønbæk Tidemand, Martin Cramer Pedersen, Pie Huda, Jens Berndtsson, Tamim A Darwish, Nageshewar Rao Yepuri, Anne Martel, Thomas Günther Pomorski, Andrea Bertarello, Mark S P Sansom, Mikaela Rapp, Ramon Crehuet, Tobias Schubeis, Kresten Lindorff-Larsen, Guido Pintacuda, Lise Arleth
Mg 2+ -dependent conformational equilibria in CorA and an integrated view on transport regulation. eLife 11 (2022)
Andreas H Larsen, Laura H John, Mark S P Sansom, Robin Adam Corey
Specific interactions of peripheral membrane proteins with lipids: what can molecular simulations show us? Bioscience reports 42 (4) (2022)
Robin Adam Corey, Noah Harrison, Philllp J Stansfeld, Mark S P Sansom, Anna L Duncan
Cardiolipin, and not monolysocardiolipin, preferentially binds to the interface of complexes III and IV. Chemical science 13 (45) (2022)
Robin Adam Corey, Noah Harrison, Philllp J Stansfeld, Mark S P Sansom, Anna L Duncan
Cardiolipin, and not monolysocardiolipin, preferentially binds to the interface of complexes III and IV. Chemical science 13 (45) (2022)
Maia Kinnebrew, Rachel E Woolley, Tillson Bertie Ansell, Eamon F X Byrne, Sara Frigui, Giovanni Luchetti, Ria Sircar, Sigrid Nachtergaele, Laurel Mydock-McGrane, Kathiresan Krishnan, Simon Newstead, Mark S P Sansom, Douglas F Covey, Christian Siebold, Rajat Rohatgi
Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain. Science advances 8 (22) (2022)
Robin Adam Corey, Noah Harrison, Philllp J Stansfeld, Mark S P Sansom, Anna L Duncan
Cardiolipin, and not monolysocardiolipin, preferentially binds to the interface of complexes III and IV. Chemical science 13 (45) (2022)
Sebastian Jojoa Cruz, Kei Saotome, Che Chun Alex Tsui, Wen-Hsin Lee, Mark S P Sansom, Swetha E Murthy, Ardem Patapoutian, Andrew B Ward
Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nature communications 13 (1) (2022)
Sarah-Beth T A Amos, Thomas C Schwarz, Jiye Shi, Benjamin P Cossins, Terry S Baker, Richard J Taylor, Robert Konrat, Mark S P Sansom
Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR. The journal of physical chemistry. B 125 (11) (2021)
Martin Calvelo, Charlotte I Lynch, Juan R Granja, Mark S P Sansom, Rebeca García-Fandino
Effect of Water Models on Transmembrane Self-Assembled Cyclic Peptide Nanotubes. ACS nano 15 (4) (2021)
Robin Adam Corey, Wanling Song, Anna L Duncan, Tillson Bertie Ansell, Mark S P Sansom, Phillip J Stansfeld
Identification and assessment of cardiolipin interactions with E. coli inner membrane proteins. Science advances 7 (34) (2021)
Katharine Hammond, Flaviu Cipcigan, Kareem Al Nahas, Valeria Losasso, Helen Lewis, Jehangir Cama, Fausto Martelli, Patrick W Simcock, Marcus Fletcher, Jascindra Ravi, Phillip J Stansfeld, Stefano Pagliara, Bart W Hoogenboom, Ulrich Felix Keyser, Mark S P Sansom, Jason Crain, Maxim G Ryadnov
Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation. ACS nano 15 (6) (2021)
Andreas Haahr Larsen, Lilya Tata, Laura H John, Mark S P Sansom
Membrane-binding mechanism of the EEA1 FYVE domain revealed by multi-scale molecular dynamics simulations. PLoS computational biology 17 (9) (2021)
Shanlin Rao, Gianni Klesse, Charlotte I Lynch, Stephen J Tucker, Mark S P Sansom
Molecular Simulations of Hydrophobic Gating of Pentameric Ligand Gated Ion Channels: Insights into Water and Ions. The journal of physical chemistry. B 125 (4) (2021)
T Bertie Ansell, Luke Curran, Michael R Horrell, Tanadet Pipatpolkai, Suzanne C Letham, Wanling Song, Christian Siebold, Phillip J Stansfeld, Mark S P Sansom, Robin Adam Corey
Relative Affinities of Protein-Cholesterol Interactions from Equilibrium Molecular Dynamics Simulations. Journal of chemical theory and computation 17 (10) (2021)
Patrick W Simcock, Maike Bublitz, Flaviu Cipcigan, Maxim G Ryadnov, Jason Crain, Phillip J Stansfeld, Mark S P Sansom
Membrane Binding of Antimicrobial Peptides Is Modulated by Lipid Charge Modification. Journal of chemical theory and computation 17 (2) (2021)
Charlotte I Lynch, Gianni Klesse, Shanlin Rao, Stephen J Tucker, Mark S P Sansom
Water Nanoconfined in a Hydrophobic Pore: Molecular Dynamics Simulations of Transmembrane Protein 175 and the Influence of Water Models. ACS nano (2021)
Miguel A González, Alberto Zaragoza, Charlotte I Lynch, Mark S P Sansom, Chantal Valeriani
Influence of water models on water movement through AQP1. The Journal of chemical physics 155 (15) (2021)
Alexis Belessiotis-Richards, Stuart G Higgins, Mark S P Sansom, Alfredo Alexander-Katz, Molly M Stevens
Coarse-Grained Simulations Suggest the Epsin N-Terminal Homology Domain Can Sense Membrane Curvature without Its Terminal Amphipathic Helix. ACS nano (2020)
Eiji Yamamoto, Jan Domański, Fiona B Naughton, Robert B Best, Antreas C Kalli, Phillip J Stansfeld, Mark S P Sansom
Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes. Science advances 6 (8) (2020)
Charlotte I Lynch, Shanlin Rao, Mark S P Sansom
Water in Nanopores and Biological Channels: A Molecular Simulation Perspective. Chemical reviews 120 (18) (2020)
Gianni Klesse, Stephen J Tucker, Mark S P Sansom
Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT3 Receptor Channel. ACS nano 14 (8) (2020)
Anna L Duncan, Robin Adam Corey, Mark S P Sansom
Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels. Proceedings of the National Academy of Sciences of the United States of America 117 (14) (2020)
Arvind Kumar, Sandip Basak, Shanlin Rao, Yvonne Gicheru, Megan L Mayer, Mark S P Sansom, Sudha Chakrapani
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nature communications 11 (1) (2020)
Vanessa Judith Flegler, Akiko Rasmussen, Shanlin Rao, Na Wu, Renato Zenobi, Mark S P Sansom, Rainer Hedrich, Tim Rasmussen, Bettina Boettcher
The MscS-like channel YnaI has a gating mechanism based on flexible pore helices. Proceedings of the National Academy of Sciences of the United States of America 117 (46) (2020)
Lukas S Stelzl, Despoina A I Mavridou, Emmanuel Saridakis, Diego Gonzalez, Andrew J Baldwin, Stuart J Ferguson, Mark S P Sansom, Christina Redfield
Local frustration determines loop opening during the catalytic cycle of an oxidoreductase. eLife 9 (2020)
Gianni Klesse, Shanlin Rao, Stephen J Tucker, Mark S P Sansom
Induced Polarization in Molecular Dynamics Simulations of the 5-HT3 Receptor Channel. Journal of the American Chemical Society 142 (20) (2020)
Jan Domański, Mark S P Sansom, Phillip J Stansfeld, Robert B Best
Atomistic mechanism of transmembrane helix association. PLoS computational biology 16 (6) (2020)
Shanlin Rao, Gianni Klesse, Phillip J Stansfeld, Stephen J Tucker, Mark S P Sansom
A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates. Proceedings of the National Academy of Sciences of the United States of America 116 (28) (2019)
Marc Baaden, Mihail Barboiu, Roslyn M Bill, Serena Casanova, Chun-Long Chen, Matthew Conner, Viatcheslav Freger, Bing Gong, Artur Góra, Bruce Hinds, Andreas Horner, Gerhard Hummer, Manish Kumar, Mahesh Lokesh, Sushanta Mitra, Aleksandr Noy, Peter Pohl, Aude Sadet, Mark S P Sansom, Susanna Törnroth-Horsefield, Harish Vashisth
Structure and function of natural proteins for water transport: general discussion. Faraday discussions 209 (0) (2019)
Christopher A Caffalette, Robin A Corey, Mark S P Sansom, Phillip J Stansfeld, Jochen Zimmer
A lipid gating mechanism for the channel-forming O antigen ABC transporter. Nature communications 10 (1) (2019)
Kei Saotome, Bochuan Teng, Che Chun Alex Tsui, Wen-Hsin Lee, Yu-Hsiang Tu, Joshua P Kaplan, Mark S P Sansom, Emily Ruth Liman, Andrew B Ward
Structures of the otopetrin proton channels Otop1 and Otop3. Nature structural & molecular biology 26 (6) (2019)
Siewert-Jan Marrink, Valentina Corradi, Paulo C T Souza, Helgi I Ingólfsson, D Peter Tieleman, Mark S P Sansom
Computational Modeling of Realistic Cell Membranes. Chemical reviews 119 (9) (2019)
Robin A Corey, Owen N Vickery, Mark S P Sansom, Phillip J Stansfeld
Insights into Membrane Protein-Lipid Interactions from Free Energy Calculations. Journal of chemical theory and computation 15 (10) (2019)
Sebastian Jojoa Cruz, Kei Saotome, Swetha E Murthy, Che Chun Alex Tsui, Mark S P Sansom, Ardem Patapoutian, Andrew B Ward
Cryo-EM structure of the mechanically activated ion channel OSCA1.2. eLife 7 (2018)
Matthieu Chavent, Anna L Duncan, Patrice Rassam, Oliver Birkholz, Jean Hélie, Tyler Reddy, Dmitry Beliaev, Ben Hambly, Jacob Piehler, Colin Kleanthous, Mark S P Sansom
How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins. Nature communications 9 (1) (2018)
Jan Domański, Mark S P Sansom, Phillip J Stansfeld, Robert B Best
Balancing Force Field Protein-Lipid Interactions To Capture Transmembrane Helix-Helix Association. Journal of chemical theory and computation 14 (3) (2018)
Taylor Haynes, Iain P S Smith, E Jayne Wallace, Jemma L Trick, Mark S P Sansom, Syma Khalid
Electric-Field-Driven Translocation of ssDNA through Hydrophobic Nanopores. ACS nano 12 (8) (2018)
Jérémy Esque, Mark S P Sansom, Marc Baaden, Christophe Oguey
Analyzing protein topology based on Laguerre tessellation of a pore-traversing water network. Scientific reports 8 (1) (2018)
Henriette E Autzen, Heidi Koldsø, Phillip J Stansfeld, Pontus Emanuel Gourdon, Mark S P Sansom, Poul Nissen
Interactions of a Bacterial Cu(I)-ATPase with a Complex Lipid Environment. Biochemistry 57 (28) (2018)
Shanlin Rao, Gianni Klesse, Phillip J Stansfeld, Stephen J Tucker, Mark S P Sansom
A BEST example of channel structure annotation by molecular simulation. Channels (Austin, Tex.) 11 (4) (2017)
Nathalie Willems, Ainhoa Urtizberea, Andrea F Verre, Maria Iliut, Mickael Lelimousin, Michael Hirtz, Aravind Vijayaraghavan, Mark S P Sansom
Biomimetic Phospholipid Membrane Organization on Graphene and Graphene Oxide Surfaces: A Molecular Dynamics Simulation Study. ACS nano 11 (2) (2017)
Philip W Fowler, Mark S P Sansom, Reinhart A F Reithmeier
Effect of the Southeast Asian Ovalocytosis Deletion on the Conformational Dynamics of Signal-Anchor Transmembrane Segment 1 of Red Cell Anion Exchanger 1 (AE1, Band 3, or SLC4A1). Biochemistry 56 (5) (2017)
Jemma L Trick, Chen Song, E Jayne Wallace, Mark S P Sansom
Voltage Gating of a Biomimetic Nanopore: Electrowetting of a Hydrophobic Barrier. ACS nano 11 (2) (2017)
Ehsan Nematian-Ardestani, Viwan Jarerattanachat, Prafulla Aryal, Mark S P Sansom, Stephen J Tucker
The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel. Channels (Austin, Tex.) 11 (5) (2017)
Michael V Clausen, Viwan Jarerattanachat, Elisabeth P Carpenter, Mark S P Sansom, Stephen J Tucker
Asymmetric mechanosensitivity in a eukaryotic ion channel. Proceedings of the National Academy of Sciences of the United States of America 114 (40) (2017)
Anna L Duncan, Tyler Reddy, Heidi Koldsø, Jean Hélie, Philip W Fowler, Matthieu Chavent, Mark S P Sansom
Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes. Scientific reports 7 (1) (2017)
Emre Lacin, Prafulla Aryal, Ian W Glaaser, Karthik Bodhinathan, Eric Tsai, Nidaa Marsh, Stephen J Tucker, Mark S P Sansom, Paul A Slesinger
Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of general physiology 149 (8) (2017)
Jan Domański, George Hedger, Robert B Best, Phillip J Stansfeld, Mark S P Sansom
Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association. The journal of physical chemistry. B 121 (15) (2016)
Aaron L Randolph, Younes Mokrab, Ashley L Bennett, Mark S P Sansom, Ian Scott Ramsey
Proton currents constrain structural models of voltage sensor activation. eLife 5 (2016)