Suzanne J F Kaptein (Suzanne Kaptein)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 25

Top Venues

Nature communications

Nature

Journal of medicinal chemistry

Global health action

KU Leuven, Rega Institute for Medical Research

Maastricht University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

KU Leuven, Rega Institute for Medical Research May 01 2006

Belgium

PhD :: Department of Microbiology, Immunology and Transplantation/Laboratory of Virology and Chemotherapy

Maastricht Universitair Medisch Centrum+ Dec 16 2004 - Apr 30 2006

Netherlands

PhD :: Medical Microbiology

Education History

Maastricht University Sep 01 1998 - Dec 15 2004

Netherlands

PHD :: Medical Microbiology

Maastricht University Sep 01 1992 - Jan 31 1998

Netherlands

MSC :: Health Sciences - Biomedical Sciences

Publications

Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J F Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf F W Bartenschlager
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation. Nature communications 15 (1) (2024)
Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Benoît De Boeck, Olivia Goethals, Suzanne J F Kaptein, Bart Stoops, Erwin Coesemans, Jérôme Fortin, Philippe Muller, Frédéric Doublet, Gunter Carlens, Mohamed Koukni, Wim Smets, Pierre Raboisson, Patrick Chaltin, Kenny Simmen, Marnix Van Loock, Johan Neyts, Arnaud Marchand, Tim H M Jonckers
Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor. Journal of medicinal chemistry 67 (5) (2024)
Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik-Jan Thibaut, Sebastiaan Ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J F Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Multiplexed multicolor antiviral assay amenable for high-throughput research. Nature communications 15 (1) (2024)
Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik-Jan Thibaut, Sebastiaan Ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J F Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Multiplexed multicolor antiviral assay amenable for high-throughput research. Nature communications 15 (1) (2024)
Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J F Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf F W Bartenschlager
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation. Nature communications 15 (1) (2024)
Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J F Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf F W Bartenschlager
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation. Nature communications 15 (1) (2024)
Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik-Jan Thibaut, Sebastiaan Ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J F Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Multiplexed multicolor antiviral assay amenable for high-throughput research. Nature communications 15 (1) (2024)
Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Benoît De Boeck, Olivia Goethals, Suzanne J F Kaptein, Bart Stoops, Erwin Coesemans, Jérôme Fortin, Philippe Muller, Frédéric Doublet, Gunter Carlens, Mohamed Koukni, Wim Smets, Pierre Raboisson, Patrick Chaltin, Kenny Simmen, Marnix Van Loock, Johan Neyts, Arnaud Marchand, Tim H M Jonckers
Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor. Journal of medicinal chemistry 67 (5) (2024)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature 615 (7953) (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature 615 (7953) (2023)
Emiel Michiels, Kenny Roose, Rodrigo U Gallardo, Ladan Khodaparast, Laleh Khodaparast, Rob van der Kant, Maxime Siemons, Bert Houben, Meine Ramakers, Hannah Wilkinson, Patricia Guerreiro, Nikolaos Louros, Suzanne J F Kaptein, Lorena Itatí Ibañez, Anouk Smet, Pieter Baatsen, Shu Liu, Ina Maja Vorberg, Guy Bormans, Johan Neyts, Xavier Saelens, Frederic Rousseau, Joost Schymkowitz
Author Correction: Reverse engineering synthetic antiviral amyloids. Nature communications 14 (1) (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature 615 (7953) (2023)
Annelies Wilder-Smith, Elizabeth Bailey Brickley, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda Filho, Celina Maria Turchi Martelli, Tom Solomon, Bart C Jacobs, Carlos A Pardo-Villamizar, Lyda Osorio, Beatriz Parra, Suzannah Lant, Hugh John Willison, Sonja Leonhard, Lance Turtle, Maria Lúcia Brito Ferreira, Rafael Freitas de Oliveira Franca, Louis Lambrechts, Johan Neyts, Suzanne J F Kaptein, Rosanna Peeling, Deborah Boeras, James Logan, Helen Dolk, Iêda Maria Orioli, Andreas Neumayr, Trudie Lang, Bonny Baker, Eduardo Massad, Raman Preet
The legacy of ZikaPLAN: a transnational research consortium addressing Zika. Global health action 14 (sup1) (2022)
Bert Schepens, Loes van Schie, Wim Nerinckx, Kenny Roose, Wander Van Breedam, Daria Fijalkowska, Simon Devos, Wannes Weyts, Sieglinde De Cae, Sandrine Vanmarcke, Chiara Lonigro, Hannah Eeckhaut, Dries Van Herpe, Jimmy Borloo, Ana Filipa Oliveira, João Paulo Portela Catani, Sarah Creytens, Dorien De Vlieger, Gitte Michielsen, Jackeline Cecilia Zavala Marchan, George D Moschonas, Iebe Rossey, Koen Sedeyn, Annelies Van Hecke, Xin Zhang, Lana Langendries, Sofie Jacobs, Sebastiaan Ter Horst, Laura Seldeslachts, Laurens Liesenborghs, Robbert Boudewijns, Hendrik-Jan Thibaut, Kai Dallmeier, Greetje Vande Velde, Birgit Weynand, Julius Beer, Daniel Schnepf, Annette Ohnemus, Isabel Remory, Shi-Yan Caroline Foo, Rana Abdelnabi, Piet Maes, Suzanne J F Kaptein, Joana Rocha-Pereira, Dirk Jochmans, Leen Delang, Frank Peelman, Peter Staeheli, Martin Schwemmle, Nick Devoogdt, Dominique Tersago, Massimiliano Germani, James T Heads, Alistair J Henry, Andrew Popplewell, Mark Ellis, Kevin Brady, Alison Turner, Bruno Dombrecht, Catelijne Stortelers, Johan Neyts, Nico Callewaert, Xavier Saelens
An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models. Science translational medicine 13 (621) (2021)
Fabien Aubry, Sofie Jacobs, Maïlis Darmuzey, Sébastian Lequime, Leen Delang, Albin Fontaine, Natapong Jupatanakul, Elliott F Miot, Stéphanie Dabo, Caroline Manet, Xavier Montagutelli, Artem Baidaliuk, Fabiana Gámbaro, Etienne Simon-Loriere, Maxime Gilsoul, Claudia M Romero-Vivas, Van-Mai Cao-Lormeau, Richard G Jarman, Cheikh T Diagne, Oumar Faye, Ousmane Faye, Amadou A Sall, Johan Neyts, Laurent Nguyen, Suzanne J F Kaptein, Louis Lambrechts
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains. Nature communications 12 (1) (2021)
Suzanne J F Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Bart Stoops, Tim H M Jonckers, Kai Dallmeier, Peggy Geluykens, Kim Thys, Marjolein Crabbe, Laurent Chatel-Chaix, Max Münster, Gilles Querat, Franck Touret, Xavier de Lamballerie, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Marnix Van Loock, Johan Neyts
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. Nature 598 (7881) (2021)
Suzanne J F Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan Ter Horst, Laurens Liesenborghs, Bart Hens, Valentijn Vergote, Elisabeth Heylen, Karine Barthelemy, Elke Maas, Carolien De Keyzer, Lindsey Bervoets, Jasper Rymenants, Tina Van Buyten, Xin Zhang, Rana Abdelnabi, Juanita Pang, Rachel Williams, Hendrik-Jan Thibaut, Kai Dallmeier, Robbert Boudewijns, Jens Wouters, Patrick Augustijns, Nick Verougstraete, Christopher J Cawthorne, Judith Breuer, Caroline Solas, Birgit Weynand, Pieter Annaert, Isabel Spriet, Greetje Vande Velde, Johan Neyts, Joana Rocha-Pereira, Leen Delang
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity. Proceedings of the National Academy of Sciences of the United States of America 117 (43) (2020)
Emiel Michiels, Kenny Roose, Rodrigo U Gallardo, Ladan Khodaparast, Laleh Khodaparast, Rob van der Kant, Maxime Siemons, Bert Houben, Meine Ramakers, Hannah Wilkinson, Patricia Guerreiro, Nikolaos Louros, Suzanne J F Kaptein, Lorena Itatí Ibañez, Anouk Smet, Pieter Baatsen, Shu Liu, Ina Maja Vorberg, Guy Bormans, Johan Neyts, Xavier Saelens, Frederic Rousseau, Joost Schymkowitz
Reverse engineering synthetic antiviral amyloids. Nature communications 11 (1) (2020)
Annelies Wilder-Smith, Raman Preet, Elizabeth Bailey Brickley, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda Filho, Celina Maria Turchi Martelli, Thália Velho Barreto de Araújo, Ulisses Ramos Montarroyos, Maria Elisabeth Moreira, Marília Dalva Turchi, Tom Solomon, Bart C Jacobs, Carlos Pardo Villamizar, Lyda Osorio, Ana Maria Bispo de Filipps, Johan Neyts, Suzanne J F Kaptein, Ralph Huits, Kevin K Ariën, Hugh John Willison, Julia M Edgar, Susan C Barnett, Rosanna Peeling, Debi Boeras, Maria G Guzman, Aravinda M de Silva, Andrew K Falconar, Claudia Romero-Vivas, Michael W Gaunt, Alessandro Sette, Daniela Weiskopf, Louis Lambrechts, Helen Dolk, Joan K Morris, Iêda Maria Orioli, Kathleen M O'Reilly, Laith Yakob, Joacim Rocklöv, Cristiane Soares, Maria Lúcia Brito Ferreira, Rafael Freitas de Oliveira Franca, Alexander Roberto Precioso, James Logan, Trudie Lang, Nina Jamieson, Eduardo Massad
ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. Global health action 12 (1) (2020)
Sapna Sharma, Michael Alexander Schmid, Lorena Sanchez-Felipe, Jana Grenelle, Suzanne J F Kaptein, Lotte Coelmont, Johan Neyts, Kai Dallmeier
Small-molecule inhibitors of TBK1 serve as an adjuvant for a plasmid-launched live-attenuated yellow fever vaccine. Human vaccines & immunotherapeutics 16 (9) (2020)
Robbert Boudewijns, Hendrik-Jan Thibaut, Suzanne J F Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, Thomas Vercruysse, Xinyu Wang, Dirk Jochmans, Erik Martens, Kenny Roose, Dorien De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, Bert Vanmechelen, Tony Wawina-Bokalanga, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Winston Chiu, Pieter Leyssen, Elisabeth Heylen, Dominique Schols, Lanjiao Wang, Lila Close, Jelle Matthijnssens, Marc Van Ranst, Veerle Compernolle, Georg Schramm, Koen Van Laere, Xavier Saelens, Nico Callewaert, Ghislain Opdenakker, Piet Maes, Birgit Weynand, Christopher J Cawthorne, Greetje Vande Velde, Zhongde Wang, Johan Neyts, Kai Dallmeier
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters. Nature communications 11 (1) (2020)
César Muñoz-Fontela, William E Dowling, Simon G P Funnell, Pierre-S Gsell, A Ximena Riveros-Balta, Randy A Albrecht, Hanne A Elyard, Ralph S Baric, Miles W Carroll, Marco Cavaleri, Chuan Qin, Ian Crozier, Kai Dallmeier, Leon de Waal, Emmie de Wit, Leen Delang, Erik Dohm, W Paul Duprex, Darryl Falzarano, Courtney L Finch, Matthew B Friemann, Barney S Graham, Lisa E Gralinski, Kate Guilfoyle, Bart L Haagmans, Geraldine A Hamilton, Amy L Hartman, Sander Herfst, Suzanne J F Kaptein, William B Klimstra, Ivana Knezevic, Philip R Krause, J Thomas Beatty, Roger Le Grand, Mark G Lewis, Wen-Chun Liu, Pauline Maisonnasse, Anita K McElroy, Vincent J Munster, Nadia Oreshkova, Angela L Rasmussen, Joana Rocha-Pereira, Barry Rockx, Estefanía Rodríguez, Thomas F Rogers, Francisco J Salguero, Michael Schotsaert, Koert J Stittelaar, Hendrik-Jan Thibaut, Chien-Te Tseng, Júlia Vergara-Alert, Martin Beer, Trevor Brasel, Jasper F W Chan, Adolfo García-Sastre, Johan Neyts, Stanley Perlman, Douglas S Reed, Juergen A Richt, Chad J Roy, Joaquim Segalés, Seshadri S Vasan, Ana María Henao-Restrepo, Dan H Barouch
Animal models for COVID-19. Nature 586 (7830) (2020)
Lorena Sanchez-Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Dominique Van Looveren, Mahadesh Prasad Arkalagud Javarappa, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs, Suzanne J F Kaptein, Carolien De Keyzer, Lindsey Bervoets, Sarah Debaveye, Madina Rasulova, Laura Seldeslachts, Li-Hsin Li, Sander Jansen, Michael Bright Yakass, Babs E Verstrepen, Kinga P Böszörményi, Gwendoline Kiemenyi-Kayere, Nikki van Driel, Osbourne Quaye, Xin Zhang, Sebastiaan Ter Horst, Niraj Mishra, Ward Deboutte, Jelle Matthijnssens, Lotte Coelmont, Corinne Vandermeulen, Elisabeth Heylen, Valentijn Vergote, Dominique Schols, Zhongde Wang, Willy M J M Bogers, Thijs Kuiken, Ernst J Verschoor, Christopher J Cawthorne, Koen Van Laere, Ghislain Opdenakker, Greetje Vande Velde, Birgit Weynand, Dirk E Teuwen, Patrick Matthys, Johan Neyts, Hendrik-Jan Thibaut, Kai Dallmeier
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate. Nature 590 (7845) (2020)
Sofie Jacobs, Leen Delang, Eric Verbeken, Johan Neyts, Suzanne J F Kaptein
A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice. International journal of molecular sciences 20 (9) (2019)

Suzanne J F Kaptein.css-eqlu8i{font-size:small;padding-left:4px;} (Suzanne Kaptein)

Publication Activity (10 Years)

Top Topics

Top Venues

Suzanne J F Kaptein (Suzanne Kaptein)