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Christina S Leslie (Christina Leslie, C S Leslie)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 36

Top Venues

Nature communications

Nature immunology

Genome biology

Nature

Memorial Sloan-Kettering Cancer Center

University of California Berkeley (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Memorial Sloan-Kettering Cancer Center Jul 1o 2007

United States

Associate Member :: Computational and Systems Biology Program

Education History

University of California Berkeley

United States

PHD :: Mathematics

Publications

Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Andreas R Gschwind, Kristy S Mualim, Alireza Karbalayghareh, Maya U Sheth, Kushal K Dey, Evelyn Jagoda, Ramil N Nurtdinov, Wang Xi, Anthony S Tan, Hank Jones, X Rosa Ma, David Yao, Joseph Nasser, Žiga Avsec, Benjamin T James, Muhammad Saad Shamim, Neva C Durand, Suhas S P Rao, Ragini Mahajan, Benjamin R Doughty, Kalina Andreeva, Jacob C Ulirsch, Kaili Fan, Elizabeth M Perez, Tri C Nguyen, David R Kelley, Hilary K Finucane, Jill E Moore, Nishigandha Phalke, Manolis Kellis, Michael C Bassik, Alkes L Price, Michael A Beer, Roderic Guigo, John A Stamatoyannopoulos, Erez Lieberman Aiden, William J Greenleaf, Christina S Leslie, Lars M Steinmetz, Anshul Kundaje, Jesse M Engreitz
An encyclopedia of enhancer-gene regulatory interactions in the human genome. bioRxiv : the preprint server for biology (2023)
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Rui Yang, Arnav Das, Vianne R Gao, Alireza Karbalayghareh, William S Noble, Jeffery A Bilmes, Christina S Leslie
Epiphany: predicting Hi-C contact maps from 1D epigenomic signals. Genome biology 24 (1) (2023)
Melanie H Smith, Vianne R Gao, Preethi K Periyakoil, Alejandro Kochen, Edward F DiCarlo, Susan M Goodman, Thomas M Norman, Laura T Donlin, Christina S Leslie, Alexander Y Rudensky
Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis. Nature immunology (2023)
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Ashlesha Odak, Han Yuan, Judith Feucht, Vito Adrian Cantu, Jorge Mansilla-Soto, Friederike Kogel, Justin Eyquem, John K Everett, Frederic D Bushman, Christina S Leslie, Michel Sadelain
Novel extragenic genomic safe harbors for precise therapeutic T cell engineering. Blood (2023)
Ashlesha Odak, Han Yuan, Judith Feucht, Vito Adrian Cantu, Jorge Mansilla-Soto, Friederike Kogel, Justin Eyquem, John K Everett, Frederic D Bushman, Christina S Leslie, Michel Sadelain
Novel extragenic genomic safe harbors for precise therapeutic T cell engineering. Blood (2023)
Vianne R Gao, Rui Yang, Arnav Das, Renhe Luo, Hanzhi Luo, Dylan R McNally, Ioannis Karagiannidis, Martín A Rivas, Zhong-Min Wang, Darko Barisic, Alireza Karbalayghareh, Wilfred Wong, Yingqian Ada Zhan, Christopher R Chin, William Noble, Jeff A Bilmes, Effie Apostolou, Michael Gregory Kharas, Wendy Béguelin, Aaron D Viny, Danwei Huangfu, Alexander Y Rudensky, Ari M Melnick, Christina S Leslie
ChromaFold predicts the 3D contact map from single-cell chromatin accessibility. bioRxiv : the preprint server for biology (2023)
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Allison R Pine, Stefano M Cirigliano, Richa Singhania, James G Nicholson, Barbara Da Silva, Christina S Leslie, Howard A Fine
Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution. Cancer research (2023)
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y Q Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T T Nguyen, Gabriela Chiosis, Alex Kentsis, Christina S Leslie, Ly Phuong Vu, Michael Gregory Kharas
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature communications 14 (1) (2023)
Dapeng Yang, Hyunwoo Cho, Zakieh Tayyebi, Abhijit Shukla, Renhe Luo, Gary Dixon, Valeria Ursu, Stephanie Stransky, Daniel M Tremmel, Sara D Sackett, Richard P Koche, Samuel J Kaplan, Qing V Li, Jiwoon Park, Zengrong Zhu, Bess P Rosen, Julian Pulecio, Zhong-Dong Shi, Yaron Bram, Robert E Schwartz, Jon S Odorico, Simone Sidoli, Christopher V Wright, Christina S Leslie, Danwei Huangfu
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nature cell biology 24 (7) (2022)
Yuchen Xie, Merve Sahin, Sonali Sinha, Yufeng Wang, Amrita M Nargund, Yang Lyu, Song Han, Yiyu Dong, James J Hsieh, Christina S Leslie, Emily H Cheng
SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes. Nature cancer 3 (2) (2022)
Briana G Nixon, Chun Chou, Chirag Krishna, Saïda Dadi, Adam O Michel, Andrew E Cornish, Emily R Kansler, Mytrang H Do, Xinxin Wang, Kristelle J Capistrano, Alexander Y Rudensky, Christina S Leslie, Ming O Li
Cytotoxic granzyme C-expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity. Science immunology 7 (70) (2022)
Francisco J Sánchez-Rivera, Bianca J Diaz, Edward R Kastenhuber, Henri Schmidt, Alyna Katti, Margaret C Kennedy, Vincent Tem, Yu-Jui Ho, Josef Leibold, Stella V Paffenholz, Francisco M Barriga, Kevan Chu, Sukanya Goswami, Alexandra N Wuest, Janelle M Simon, Kaloyan M Tsanov, Debyani Chakravarty, Hongxin Zhang, Christina S Leslie, Scott W Lowe, Lukas E Dow
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. Nature biotechnology 40 (6) (2022)
Emily R Kansler, Saïda Dadi, Chirag Krishna, Briana G Nixon, Efstathios Gregorios Stamatiades, Ming Liu, Fengshen Kuo, Jing Zhang, Xian Zhang, Kristelle Capistrano, Kyle A Blum, Kate Weiss, Ross M Kedl, Guangwei Cui, Koichi Ikuta, Timothy A Chan, Christina S Leslie, Abraham Ari Hakimi, Ming O Li
Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies. Nature immunology 23 (6) (2022)
Erik Ladewig, Flavia Michelini, Komal Jhaveri, Hatice Ulku Osmanbeyoglu, Javier Carmona, Lauren Fairchild, Adler G Zuniga, Amaia Arruabarrena-Aristorena, Emiliano Cocco, Ryan Blawski, Srushti Kittane, Yuhan Zhang, Mirna Sallaku, Laura Baldino, Vasilis Hristidis, Sarat Chandarlapaty, Omar Abdel-Wahab, Christina S Leslie, Maurizio Scaltriti, Eneda Toska
The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation. Cancer research 82 (12) (2022)
Blossom Akagbosu, Zakieh Tayyebi, Gayathri Shibu, Yoselin A Paucar Iza, Deeksha Deep, Yollanda Franco Parisotto, Logan Fisher, H Amalia Pasolli, Valentin Thevin, Rasa Elmentaite, Maximilian Martin Ludwig Knott, Saskia Hemmers, Lorenz Jahn, Christin Friedrich, Jacob G Verter, Zhong-Min Wang, Marcel R M van den Brink, Georg Gasteiger, Thomas G P Grünewald, Julien C Marie, Christina S Leslie, Alexander Y Rudensky, Chrysothemis C Brown
Novel antigen-presenting cell imparts T reg -dependent tolerance to gut microbiota. Nature 610 (7933) (2022)
Meghana Kshirsagar, Han Yuan, Juan Lavista Ferres, Christina S Leslie
BindVAE: Dirichlet variational autoencoders for de novo motif discovery from accessible chromatin. Genome biology 23 (1) (2022)
Chun Chou, Xian Zhang, Chirag Krishna, Briana G Nixon, Saida Dadi, Kristelle J Capistrano, Emily R Kansler, Miranda Steele, Jian Han, Amy Shyu, Jing Zhang, Efstathios Gregorios Stamatiades, Ming Liu, Shun Li, Mytrang H Do, Chaucie Edwards, Davina S Kang, Chin-Tung Chen, Iris H Wei, Emmanouil P Pappou, Martin R Weiser, Julio Garcia-Aguilar, J Joshua Smith, Christina S Leslie, Ming O Li
Programme of self-reactive innate-like T cell-mediated cancer immunity. Nature 605 (7908) (2022)
S Dhara, Sagar Chhangawala, H Chintalapudi, G Askan, V Aveson, Alexandra Massa, L Zhang, D Torres, Alvin P Makohon-Moore, N Lecomte, J P Melchor, J Bermeo, A Cardenas, S Sinha, Danielle Glassman, Remy Nicolle, Richard A Moffitt, K H Yu, S Leppanen, S Laderman, B Curry, J Gui, Vinod P Balachandran, Christine A Iacobuzio-Donahue, R Chandwani, Christina S Leslie, S D Leach
Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility. Nature communications 12 (1) (2021)
Olivier Elemento, Christina S Leslie, Johan Lundin, Georgia Tourassi
Artificial intelligence in cancer research, diagnosis and therapy. Nature reviews. Cancer 21 (12) (2021)
Merve Sahin, Wilfred Wong, Yingqian Ada Zhan, Kinsey Van Deynze, Richard P Koche, Christina S Leslie
HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. Nature communications 12 (1) (2021)
Yi Zhong, Sarah K Walker, Yuri Pritykin, Christina S Leslie, Alexander Y Rudensky, Joris van der Veeken
Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families. Nature immunology 23 (1) (2021)
Guotai Xu, Sagar Chhangawala, Emiliano Cocco, Pedram Razavi, Yanyan Cai, Jordan E Otto, Lorenzo Ferrando, Pier Selenica, Erik Ladewig, Carmen Chan, Arnaud Da Cruz Paula, Matthew Witkin, Yuanming Cheng, Jane Park, Cristian Serna-Tamayo, HuiYong Zhao, Fan Wu, Mirna Sallaku, Xuan Qu, Alison Zhao, Clayton K Collings, Andrew R D'Avino, Komal Jhaveri, Richard P Koche, Ross L Levine, Jorge Sergio Reis-Filho, Cigall Kadoch, Maurizio Scaltriti, Christina S Leslie, Jose Baselga, Eneda Toska
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer. Nature genetics 52 (2) (2020)
Diu T T Nguyen, Yuheng Lu, Karen L Chu, Xuejing Yang, Sun-Mi Park, Zi-Ning Choo, Christopher R Chin, Camila Prieto, Alexandra Schurer, Ersilia Barin, Angela M Savino, Saroj Gourkanti, Payal Patel, Ly P Vu, Christina S Leslie, Michael Gregory Kharas
HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells. Nature communications 11 (1) (2020)
Gerard Minuesa, Steven K Albanese, Wei Xie, Yaniv Kazansky, Daniel Worroll, Arthur Chow, Alexandra Schurer, Sun-Mi Park, Christina Z Rotsides, James Taggart, Andrea Rizzi, Levi N Naden, Timothy Chou, Saroj Gourkanti, Daniel Cappel, Maria C Passarelli, Lauren Fairchild, Carolina Adura, J Fraser Glickman, Jessica Schulman, Christopher Famulare, Minal Patel, Joseph K Eibl, Gregory M Ross, Shibani Bhattacharya, Derek S Tan, Christina S Leslie, Thijs Beuming, Dinshaw J Patel, Yehuda Goldgur, John D Chodera, Michael Gregory Kharas
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nature communications 10 (1) (2019)
Han Yuan, Meghana Kshirsagar, Lee Zamparo, Yuheng Lu, Christina S Leslie
BindSpace decodes transcription factor binding signals by large-scale sequence embedding. Nature methods 16 (9) (2019)
Catherine Konopacki, Yuri Pritykin, Yury P Rubtsov, Christina S Leslie, Alexander Y Rudensky
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function. Nature immunology 20 (2) (2019)
Orr-El Weizman, Eric Song, Nicholas M Adams, Andrew D Hildreth, Luke Riggan, Chirag Krishna, Oscar A Aguilar, Christina S Leslie, James R Carlyle, Joseph C Sun, Timothy E O'Sullivan
Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12. Nature immunology 20 (8) (2019)
Hatice Ulku Osmanbeyoglu, Fumiko Shimizu, Angela Rynne-Vidal, Direna Alonso-Curbelo, Hsuan-An Chen, Hannah Y Wen, Tsz-Lun Yeung, Petar Jelinic, Pedram Razavi, Scott W Lowe, Samuel C Mok, Gabriela Chiosis, Douglas A Levine, Christina S Leslie
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers. Nature communications 10 (1) (2019)
Jing-Ping Hsin, Yuheng Lu, Gabriel B Loeb, Christina S Leslie, Alexander Y Rudensky
The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types. Nature immunology 19 (10) (2018)
Eneda Toska, Hatice U Osmanbeyoglu, Hatice Ulku Osmanbeyoglu, Carmen Chan, Ronald C Hendrickson, Moshe Elkabets, Maura N Dickler, Maurizio Scaltriti, Christina S Leslie, Scott A Armstrong, Jose Baselga
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D. Science (New York, N.Y.) 355 (6331) (2017)

Christina S Leslie.css-eqlu8i{font-size:small;padding-left:4px;} (Christina Leslie, C S Leslie)

Publication Activity (10 Years)

Top Topics

Top Venues

Christina S Leslie (Christina Leslie, C S Leslie)