Xin He

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Venues

Nature genetics

Research square

Nature communications

Molecular psychiatry

University of Chicago

University of Illinois at Urbana-Champaign (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Chicago Sep 01 2014

United States

Assistant Professor :: Department of Human Genetics

Education History

University of Illinois at Urbana-Champaign Jan 01 2005 - Oct 31 2009

United States

PHD :: Department of Computer Science

Publications

Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics 56 (2) (2024)
Katherine A Aracena, Yen-Lung Lin, Kaixuan Luo, Alain Pacis, Saideep Gona, Zepeng Mu, Vania Yotova, Renata Sindeaux, Albena Pramatarova, Marie-Michelle Simon, Xun Chen, Cristian Groza, David R Lougheed, Romain Gregoire, David Brownlee, Carly Boye, Roger Pique-Regi, Yang Li, Xin He, David Bujold, Tomi Pastinen, Guillaume Bourque, Luis B Barreiro
Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nature genetics 56 (3) (2024)
Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran, Jubao Duan
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia. Research square (2024)
Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics 56 (2) (2024)
Katherine A Aracena, Yen-Lung Lin, Kaixuan Luo, Alain Pacis, Saideep Gona, Zepeng Mu, Vania Yotova, Renata Sindeaux, Albena Pramatarova, Marie-Michelle Simon, Xun Chen, Cristian Groza, David R Lougheed, Romain Gregoire, David Brownlee, Carly Boye, Roger Pique-Regi, Yang Li, Xin He, David Bujold, Tomi Pastinen, Guillaume Bourque, Luis B Barreiro
Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nature genetics 56 (3) (2024)
Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran, Jubao Duan
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia. Research square (2024)
Jubao Duan, Alena Kozlova, Siwei Zhang, Ari Sudwards, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia. Research square (2024)
Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics 56 (2) (2024)
Katherine A Aracena, Yen-Lung Lin, Kaixuan Luo, Alain Pacis, Saideep Gona, Zepeng Mu, Vania Yotova, Renata Sindeaux, Albena Pramatarova, Marie-Michelle Simon, Xun Chen, Cristian Groza, David R Lougheed, Romain Gregoire, David Brownlee, Carly Boye, Roger Pique-Regi, Yang Li, Xin He, David Bujold, Tomi Pastinen, Guillaume Bourque, Luis B Barreiro
Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nature genetics (2024)
Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics 56 (2) (2024)
Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics (2024)
Katherine A Aracena, Yen-Lung Lin, Kaixuan Luo, Alain Pacis, Saideep Gona, Zepeng Mu, Vania Yotova, Renata Sindeaux, Albena Pramatarova, Marie-Michelle Simon, Xun Chen, Cristian Groza, David R Lougheed, Romain Gregoire, David Brownlee, Carly Boye, Roger Pique-Regi, Yang Li, Xin He, David Bujold, Tomi Pastinen, Guillaume Bourque, Luis B Barreiro
Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nature genetics 56 (3) (2024)
Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics 56 (2) (2024)
Siming Zhao, Wesley Crouse, Sheng Qian, Kaixuan Luo, Matthew Stephens, Xin He
Adjusting for genetic confounders in transcriptome-wide association studies improves discovery of risk genes of complex traits. Nature genetics 56 (2) (2024)
Yun Li, Jia Wen, Gang Li, Jiawen Chen, Quan Sun, Weifang Liu, Wyliena Guan, Boqiao Lai, Jin P Szatkiewicz, Xin He, Patrick Sullivan
DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network. Research square (2023)
Yun Li, Jia Wen, Gang Li, Jiawen Chen, Quan Sun, Weifang Liu, Wyliena Guan, Boqiao Lai, Jin P Szatkiewicz, Xin He, Patrick Sullivan
DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network. Research square (2023)
Yifan Zhou, Kaixuan Luo, Lifan Liang, Mengjie Chen, Xin He
A new Bayesian factor analysis method improves detection of genes and biological processes affected by perturbations in single-cell CRISPR screening. Nature methods (2023)
Alan Selewa, Kaixuan Luo, Michael Wasney, Linsin Smith, Xiaotong Sun, Chenwei Tang, Heather Eckart, Ivan P Moskowitz, Anindita Basu, Xin He, Sebastian Pott
Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation. Nature communications 14 (1) (2023)
Amelia C Joslin, Débora R Sobreira, Grace T Hansen, Noboru J Sakabe, Ivy Aneas, Lindsey E Montefiori, Kathryn M Farris, Jing Gu, Donna M Lehman, Carole Ober, Xin He, Marcelo Aguiar Nobrega
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. Nature communications 12 (1) (2021)
Siwei Zhang, Hanwen Zhang, Yifan Zhou, Min Qiao, Siming Zhao, Alena Kozlova, Jianxin Shi, Alan R Sanders, Gao Wang, Kaixuan Luo, Subhajit Sengupta, Siobhan West, Sheng Qian, Michael Streit, Dimitrios Avramopoulos, Chad A Cowan, Mengjie Chen, Zhiping P Pang, Pablo V Gejman, Xin He, Jubao Duan
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants. Science (New York, N.Y.) 369 (6503) (2020)
Jean Morrison, Nicholas Knoblauch, Joseph H Marcus, Matthew Stephens, Xin He
Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics. Nature genetics 52 (7) (2020)
Tan-Hoang Nguyen, Amanda Dobbyn, Ruth C Brown, Brien P Riley, Joseph D Buxbaum, Dalila Pinto, Shaun M Purcell, Patrick F Sullivan, Xin He, Eli A Stahl
mTADA is a framework for identifying risk genes from de novo mutations in multiple traits. Nature communications 11 (1) (2020)
Zijie Zhang, Kaixuan Luo, Zhongyu Zou, Maguanyun Qiu, Jiakun Tian, Laura Sieh, Hailing Shi, Yuxin Zou, Gao Wang, Jean Morrison, Allen C Zhu, Min Qiao, Zhongshan Li, Matthew Stephens, Xin He, Chuan He
Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability. Nature genetics 52 (9) (2020)
Noboru J Sakabe, Ivy Aneas, Nicholas Knoblauch, Débora R Sobreira, Nicole Clark, Cristina Paz, Cynthia Horth, Ryan Ziffra, Harjot Kaur, Xiao Liu, Rebecca Anderson, Jean Morrison, Virginia C Cheung, Chad A Grotegut, Timothy E Reddy, Bo Jacobson, Mikko Hallman, Kari Teramo, Amy Murtha, John A Kessler, William Grobman, Ge Zhang, Louis J Muglia, Sarosh Rana, Vincent J Lynch, Gregory E Crawford, Carole Ober, Xin He, Marcelo Aguiar Nobrega
Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth. Science advances 6 (49) (2020)
Siming Zhao, Jun Liu, Pranav Nanga, Yuwen Liu, A Ercument Cicek, Nicholas Knoblauch, Chuan He, Matthew Stephens, Xin He
Detailed modeling of positive selection improves detection of cancer driver genes. Nature communications 10 (1) (2019)
Donna M Werling, Harrison Brand, Joon-Yong An, Matthew R Stone, Lingxue Zhu, Joseph T Glessner, Ryan L Collins, Shan Dong, Ryan M Layer, Eirene Markenscoff-Papadimitriou, Andrew Farrell, Grace B Schwartz, Harold Z Wang, Benjamin B Currall, Xuefang Zhao, Jeanselle Dea, Clif Duhn, Carolyn A Erdman, Michael C Gilson, Rachita Yadav, Robert E Handsaker, Seva Kashin, Lambertus Klei, Jeffrey D Mandell, Tomasz J Nowakowski, Yuwen Liu, Sirisha Pochareddy, Louw Smith, Michael F Walker, Matthew J Waterman, Xin He, Arnold R Kriegstein, John L Rubenstein, Nenad Sestan, Steven A McCarroll, Benjamin M Neale, Hilary Coon, A Jeremy Willsey, Joseph D Buxbaum, Mark J Daly, Matthew W State, Aaron R Quinlan, Gabor T Marth, Kathryn Roeder, Bernie Devlin, Michael E Talkowski, Stephan J Sanders
An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder. Nature genetics 50 (5) (2018)
Jinchen Li, Shanshan Hu, Kun Zhang, Leisheng Shi, Yi Zhang, Tingting Zhao, Lin Wang, Xin He, Kun Xia, Chunyu Liu, Zhongsheng Sun
A comparative study of the genetic components of three subcategories of autism spectrum disorder. Molecular psychiatry 24 (11) (2018)
Jinchen Li, Lin Wang, Hui Guo, Leisheng Shi, Kun Zhang, Meina Tang, Shanshan Hu, Shanshan Dong, Yanling Liu, Tianyun Wang, Ping Yu, Xin He, Zhengmao Hu, Jinping Zhao, Chunyu Liu, Zhong Sheng Sun, Kun Xia
Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders. Molecular psychiatry 22 (9) (2017)

Xin He.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Xin He