Timothy P C Rooney

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 10

Top Topics

Structural Basis

Subarachnoid Hemorrhage

Signaling Pathway

Top Venues

Journal of medicinal chemistry

RSC medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Simon R Stockwell, Duncan E Scott, Gerhard Fischer, Estrella Guarino, Timothy P C Rooney, Tzu-Shean Feng, Tommaso Moschetti, Rajavel Srinivasan, Esther Alza, Alice Asteian, Claudio Dagostin, Anna Alcaide, Mathieu Rocaboy, Beata Blaszczyk, Alicia Higueruelo, Xuelu Wang, Maxim Rossmann, Trevor R Perrior, Tom L Blundell, David R Spring, Grahame McKenzie, Chris Abell, John Skidmore, Ashok R Venkitaraman, Marko Hyvönen
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents. Journal of medicinal chemistry (2024)
Gregory G Aldred, Timothy P C Rooney, Henriëtte M G Willems, Helen K Boffey, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K). RSC medicinal chemistry 14 (10) (2023)
Timothy P C Rooney, Gregory G Aldred, Helen K Boffey, Henriëtte M G Willems, Simon Edwards, Stephen J Chawner, Duncan E Scott, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. Journal of medicinal chemistry 66 (1) (2022)
Timothy P C Rooney, Gregory G Aldred, Helen K Boffey, Henriëtte M G Willems, Simon Edwards, Stephen J Chawner, Duncan E Scott, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. Journal of medicinal chemistry 66 (1) (2022)
Timothy P C Rooney, Gregory G Aldred, Helen K Boffey, Henriëtte M G Willems, Simon Edwards, Stephen J Chawner, Duncan E Scott, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. Journal of medicinal chemistry 66 (1) (2022)
Timothy P C Rooney, Gregory G Aldred, Helen K Boffey, Henriëtte M G Willems, Simon Edwards, Stephen J Chawner, Duncan E Scott, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. Journal of medicinal chemistry 66 (1) (2022)
Timothy P C Rooney, Gregory G Aldred, Helen K Boffey, Henriëtte M G Willems, Simon Edwards, Stephen J Chawner, Duncan E Scott, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. Journal of medicinal chemistry (2022)
Helen K Boffey, Timothy P C Rooney, Henriette M G Willems, Simon Edwards, Christopher Green, Tina Howard, Derek Ogg, Tamara Romero, Duncan E Scott, David Winpenny, James Duce, John Skidmore, Jonathan H Clarke, Stephen P Andrews
Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. Journal of medicinal chemistry 65 (4) (2022)
Timothy P C Rooney, Gregory G Aldred, Helen K Boffey, Henriëtte M G Willems, Simon Edwards, Stephen J Chawner, Duncan E Scott, Christopher Green, David Winpenny, John Skidmore, Jonathan H Clarke, Stephen P Andrews
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. Journal of medicinal chemistry 66 (1) (2022)
Michael Brand, James Clayton, Mustafa Moroglu, Matthias Schiedel, Sarah Picaud, Joseph P Bluck, Anna Skwarska, Hannah Bolland, Anthony K C Chan, Corentine M C Laurin, Amy R Scorah, Larissa See, Timothy P C Rooney, Katrina H Andrews, Oleg Fedorov, Gabriella Perell, Prakriti Kalra, Kayla B Vinh, Wilian A Cortopassi, Pascal Heitel, Kirsten E Christensen, Richard I Cooper, Robert S Paton, William C K Pomerantz, Philip Charles Biggin, Eva-Leonne Göttgens, Panagis Filippakopoulos, Stuart J Conway
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Journal of medicinal chemistry 64 (14) (2021)