Patrick C N Rensen

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 78

Top Topics

Randomized Controlled Trial

Cardiovascular Disease

Top Venues

Scientific reports

Arteriosclerosis, thrombosis, and vascular biology

This page only lists publications with an associated author ORCID identifier.

Publications

Frank H Schaftenaar, Andrea D van Dam, Gerjan de Bruin, Marie A C Depuydt, Jill de Mol, Jacob Amersfoort, Hidde Douna, Menno Meijer, Mara J Kröner, Peter J van Santbrink, Mireia N A Bernabé Kleijn, Gijs H M van Puijvelde, Bogdan I Florea, Bram Slütter, Amanda C Foks, Ilze Bot, Patrick C N Rensen, Johan Kuiper
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (6) (2024)
Anouk I M van der Velden, Angela Koudijs, Sander Kooijman, Rosalie G J Rietjens, Wendy M P J Sol, M Cristina Avramut, Gangqi Wang, Patrick C N Rensen, Ton J Rabelink, Johan van der Vlag, Bernard M van den Berg
Fasting mimicking diet in diabetic mice partially preserves glomerular endothelial glycocalyx coverage, without changing the diabetic metabolic environment. American journal of physiology. Renal physiology 326 (5) (2024)
Frank H Schaftenaar, Andrea D van Dam, Gerjan de Bruin, Marie A C Depuydt, Jill de Mol, Jacob Amersfoort, Hidde Douna, Menno Meijer, Mara J Kröner, Peter J van Santbrink, Mireia N A Bernabé Kleijn, Gijs H M van Puijvelde, Bogdan I Florea, Bram Slütter, Amanda C Foks, Ilze Bot, Patrick C N Rensen, Johan Kuiper
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (6) (2024)
Lushun Yuan, Aswin Verhoeven, Niek Blomberg, Huub J van Eyk, Maurice B Bizino, Patrick C N Rensen, Ingrid M Jazet, Hildo J Lamb, Ton J Rabelink, Martin A Giera, Bernard M van den Berg
Ethnic Disparities in Lipid Metabolism and Clinical Outcomes between Dutch South Asians and Dutch White Caucasians with Type 2 Diabetes Mellitus. Metabolites 14 (1) (2024)
Frank H Schaftenaar, Andrea D van Dam, Gerjan de Bruin, Marie A C Depuydt, Jill de Mol, Jacob Amersfoort, Hidde Douna, Menno Meijer, Mara J Kröner, Peter J van Santbrink, Mireia N A Bernabé Kleijn, Gijs H M van Puijvelde, Bogdan I Florea, Bram Slütter, Amanda C Foks, Ilze Bot, Patrick C N Rensen, Johan Kuiper
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (6) (2024)
Carla Cofiño-Fabres, Tom Boonen, José Manuel Rivera-Arbeláez, Minke Rijpkema, Lisanne Blauw, Patrick C N Rensen, Verena Schwach, Marcelo C Ribeiro, Robert Passier
Micro-Engineered Heart Tissues On-Chip with Heterotypic Cell Composition Display Self-Organization and Improved Cardiac Function. Advanced healthcare materials (2024)
Lushun Yuan, Aswin Verhoeven, Niek Blomberg, Huub J van Eyk, Maurice B Bizino, Patrick C N Rensen, Ingrid M Jazet, Hildo J Lamb, Ton J Rabelink, Martin A Giera, Bernard M van den Berg
Ethnic Disparities in Lipid Metabolism and Clinical Outcomes between Dutch South Asians and Dutch White Caucasians with Type 2 Diabetes Mellitus. Metabolites 14 (1) (2024)
Carla Cofiño-Fabres, Tom Boonen, José Manuel Rivera-Arbeláez, Minke Rijpkema, Lisanne Blauw, Patrick C N Rensen, Verena Schwach, Marcelo C Ribeiro, Robert Passier
Micro-Engineered Heart Tissues on-Chip with Heterotypic Cell Composition Display Self-Organization and Improved Cardiac Function. Advanced healthcare materials (2024)
Lushun Yuan, Aswin Verhoeven, Niek Blomberg, Huub J van Eyk, Maurice B Bizino, Patrick C N Rensen, Ingrid M Jazet, Hildo J Lamb, Ton J Rabelink, Martin A Giera, Bernard M van den Berg
Ethnic Disparities in Lipid Metabolism and Clinical Outcomes between Dutch South Asians and Dutch White Caucasians with Type 2 Diabetes Mellitus. Metabolites 14 (1) (2024)
Frank H Schaftenaar, Andrea D van Dam, Gerjan de Bruin, Marie A C Depuydt, Jill de Mol, Jacob Amersfoort, Hidde Douna, Menno Meijer, Mara J Kröner, Peter J van Santbrink, Mireia N A Bernabé Kleijn, Gijs H M van Puijvelde, Bogdan I Florea, Bram Slütter, Amanda C Foks, Ilze Bot, Patrick C N Rensen, Johan Kuiper
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice. Arteriosclerosis, thrombosis, and vascular biology (2024)
Carla Cofiño-Fabres, Tom Boonen, José Manuel Rivera-Arbeláez, Minke Rijpkema, Lisanne Blauw, Patrick C N Rensen, Verena Schwach, Marcelo C Ribeiro, Robert Passier
Micro-Engineered Heart Tissues On-Chip with Heterotypic Cell Composition Display Self-Organization and Improved Cardiac Function. Advanced healthcare materials 13 (18) (2024)
Melanie Modder, Wietse In Het Panhuis, Mohan Li, Salwa Afkir, Alexandra L Dorn, Amanda C M Pronk, Trea C M Streefland, Reshma A Lalai, Stefan Pierrou, Stefan K Nilsson, Gunilla Olivecrona, Sander Kooijman, Patrick C N Rensen, Milena Schönke
Liver-targeted Angptl4 silencing by antisense oligonucleotide treatment attenuates hyperlipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice. Cardiovascular research (2024)
Sheng Li, Zhixiong Ying, Max Gentenaar, Patrick C N Rensen, Sander Kooijman, Jenny A Visser, Onno C Meijer, Jan Kroon
Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome. Journal of the Endocrine Society 8 (1) (2023)
Xinyu Di, Borja Martinez-Tellez, Elke H J Krekels, Lucas Jurado-Fasoli, Francisco J Osuna-Prieto, Lourdes Ortiz-Alvarez, Thomas Hankemeier, Patrick C N Rensen, Jonatan R Ruiz, Isabelle Kohler
Higher plasma levels of endocannabinoids and analogues correlate with a worse cardiometabolic profile in young adults. The Journal of clinical endocrinology and metabolism (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Artemiy Kovynev, Zhixiong Ying, Joost M Lambooij, Hendrik J P van der Zande, Bruno Guigas, Patrick C N Rensen, Milena Schönke
Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease. Journal of clinical and translational hepatology 11 (5) (2023)
Lushun Yuan, Ruifang Li-Gao, Aswin Verhoeven, Huub J van Eyk, Maurice B Bizino, Patrick C N Rensen, Martin A Giera, Ingrid M Jazet, Hildo J Lamb, Ton J Rabelink, Bernard M van den Berg
Altered high-density lipoprotein composition is associated with risk for complications in type 2 diabetes mellitus in South Asian descendants: A cross-sectional, case-control study on lipoprotein subclass profiling. Diabetes, obesity & metabolism (2023)
Cong Liu, Zikuan Song, Zhuang Li, Mariëtte R Boon, Milena Schönke, Patrick C N Rensen, Yanan Wang
Dietary choline increases brown adipose tissue activation markers and improves cholesterol metabolism in female APOE*3-Leiden.CETP mice. International journal of obesity (2005) 47 (3) (2023)
Cong Liu, Zikuan Song, Zhuang Li, Mariëtte R Boon, Milena Schönke, Patrick C N Rensen, Yanan Wang
Dietary choline increases brown adipose tissue activation markers and improves cholesterol metabolism in female APOE*3-Leiden.CETP mice. International journal of obesity (2005) (2023)
Wietse In Het Panhuis, Milena Schönke, Ricky Siebeler, Dorien Banen, Amanda C M Pronk, Trea C M Streefland, Salwa Afkir, Hetty C M Sips, Jan Kroon, Patrick C N Rensen, Sander Kooijman
Circadian disruption impairs glucose homeostasis in male but not in female mice and is dependent on gonadal sex hormones. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (2) (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Cong Liu, Zikuan Song, Zhuang Li, Mariëtte R Boon, Milena Schönke, Patrick C N Rensen, Yanan Wang
Dietary choline increases brown adipose tissue activation markers and improves cholesterol metabolism in female APOE*3-Leiden.CETP mice. International journal of obesity (2005) (2023)
Francisco J Osuna-Prieto, Huiwen Xu, Lourdes Ortiz-Alvarez, Xinyu Di, Isabelle Kohler, Lucas Jurado-Fasoli, José Rubio-López, Julio Plaza-Díaz, Ramiro Vilchez-Vargas, Alexander Link, Ángel Gil, Jonathan R Ruiz, Patrick C N Rensen, Borja Martinez-Tellez
The relative abundance of fecal bacterial species belonging to the Firmicutes and Bacteroidetes phyla is related to plasma levels of bile acids in young adults. Metabolomics : Official journal of the Metabolomic Society 19 (6) (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Enchen Zhou, Xiaoke Ge, Hiroyuki Nakashima, Rumei Li, Hendrik J P van der Zande, Cong Liu, Zhuang Li, Christoph Müller, Franz Bracher, Yassene Mohammed, Jan Freark de Boer, Folkert Kuipers, Bruno Guigas, Christopher K Glass, Patrick C N Rensen, Martin A Giera, Yanan Wang
Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation. EMBO molecular medicine (2023)
Wietse In Het Panhuis, Milena Schönke, Ricky Siebeler, Dorien Banen, Amanda C M Pronk, Trea C M Streefland, Salwa Afkir, Hetty C M Sips, Jan Kroon, Patrick C N Rensen, Sander Kooijman
Circadian disruption impairs glucose homeostasis in male but not in female mice and is dependent on gonadal sex hormones. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (2) (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Sheng Li, Zhixiong Ying, Max Gentenaar, Patrick C N Rensen, Sander Kooijman, Jenny A Visser, Onno C Meijer, Jan Kroon
Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome. Journal of the Endocrine Society 8 (1) (2023)
Cong Liu, Zikuan Song, Zhuang Li, Mariëtte R Boon, Milena Schönke, Patrick C N Rensen, Yanan Wang
Dietary choline increases brown adipose tissue activation markers and improves cholesterol metabolism in female APOE*3-Leiden.CETP mice. International journal of obesity (2005) 47 (3) (2023)
Francisco J Osuna-Prieto, Lucas Jurado-Fasoli, Abel Plaza-Florido, Wei Yang, Isabelle Kohler, Xinyu Di, José Rubio-López, Guillermo-Sánchez Delgado, Patrick C N Rensen, Jonathan R Ruiz, Borja Martinez-Tellez
A bout of endurance and resistance exercise transiently decreases plasma levels of bile acids in young, sedentary adults. Scandinavian journal of medicine & science in sports (2023)
Wietse In Het Panhuis, Milena Schönke, Ricky Siebeler, Dorien Banen, Amanda C M Pronk, Trea C M Streefland, Salwa Afkir, Hetty C M Sips, Jan Kroon, Patrick C N Rensen, Sander Kooijman
Circadian disruption impairs glucose homeostasis in male but not in female mice and is dependent on gonadal sex hormones. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (2) (2023)
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik J P van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick C N Rensen
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis. eLife 12 (2023)
Cong Liu, Zikuan Song, Zhuang Li, Mariëtte R Boon, Milena Schönke, Patrick C N Rensen, Yanan Wang
Dietary choline increases brown adipose tissue activation markers and improves cholesterol metabolism in female APOE*3-Leiden.CETP mice. International journal of obesity (2005) 47 (3) (2023)
Aashley S D Sardjoe Mishre, Borja Martinez-Tellez, Maaike E Straat, Mariëtte R Boon, Oleh Dzyubachyk, Andrew G Webb, Patrick C N Rensen, Hermien E Kan
Image registration and mutual thresholding enable low interimage variability across dynamic MRI measurements of supraclavicular brown adipose tissue during mild cold exposure. Magnetic resonance in medicine (2023)
Huiwen Xu, Lucas Jurado-Fasoli, Lourdes Ortiz-Alvarez, Francisco J Osuna-Prieto, Isabelle Kohler, Xinyu Di, Ramiro Vilchez-Vargas, Alexander Link, Julio Plaza-Díaz, Ángel Gil, Patrick C N Rensen, Jonathan R Ruiz, Borja Martinez-Tellez
Plasma Levels of Omega-3 and Omega-6 Derived Oxylipins Are Associated with Fecal Microbiota Composition in Young Adults. Nutrients 14 (23) (2022)
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C M Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina Clarinda Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean-Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven M Francque, Francois Pattou, Patrick C N Rensen, Bart Staels, Joel T Haas
Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism. Hepatology (Baltimore, Md.) (2022)
Dyonne Y Vos, Melinde Wijers, Marieke Smit, Nicolette Huijkman, Niels J Kloosterhuis, Justina Clarinda Wolters, Joël J Tissink, Amanda C M Pronk, Sander Kooijman, Patrick C N Rensen, Jan Albert Kuivenhoven, Bart van de Sluis
Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins. Arteriosclerosis, thrombosis, and vascular biology (2022)
Xiang Zhang, Yared Paalvast, Yanan Wang, Patrick C N Rensen, Albert K Groen
A hierarchical dynamic model used for investigating feed efficiency and its relationship with hepatic gene expression in APOE*3-Leiden.CETP mice. Physiological reports 9 (8) (2022)
Lourdes Ortiz-Alvarez, Huiwen Xu, Xinyu Di, Isabelle Kohler, Francisco J Osuna-Prieto, Francisco M Acosta, Ramiro Vilchez-Vargas, Alexander Link, Julio Plaza-Díaz, Mario van der Stelt, Thomas Hankemeier, Mercedes Clemente-Postigo, Francisco J Tinahones, Ángel Gil, Patrick C N Rensen, Jonathan R Ruiz, Borja Martinez-Tellez
Plasma Levels of Endocannabinoids and Their Analogues Are Related to Specific Fecal Bacterial Genera in Young Adults: Role in Gut Barrier Integrity. Nutrients 14 (10) (2022)
Huiwen Xu, Lucas Jurado-Fasoli, Lourdes Ortiz-Alvarez, Francisco J Osuna-Prieto, Isabelle Kohler, Xinyu Di, Ramiro Vilchez-Vargas, Alexander Link, Julio Plaza-Díaz, Ángel Gil, Patrick C N Rensen, Jonathan R Ruiz, Borja Martinez-Tellez
Plasma Levels of Omega-3 and Omega-6 Derived Oxylipins Are Associated with Fecal Microbiota Composition in Young Adults. Nutrients 14 (23) (2022)
Huiwen Xu, Lucas Jurado-Fasoli, Lourdes Ortiz-Alvarez, Francisco J Osuna-Prieto, Isabelle Kohler, Xinyu Di, Ramiro Vilchez-Vargas, Alexander Link, Julio Plaza-Díaz, Ángel Gil, Patrick C N Rensen, Jonathan R Ruiz, Borja Martinez-Tellez
Plasma Levels of Omega-3 and Omega-6 Derived Oxylipins Are Associated with Fecal Microbiota Composition in Young Adults. Nutrients 14 (23) (2022)
Huiwen Xu, Lucas Jurado-Fasoli, Lourdes Ortiz-Alvarez, Francisco J Osuna-Prieto, Isabelle Kohler, Xinyu Di, Ramiro Vilchez-Vargas, Alexander Link, Julio Plaza-Díaz, Ángel Gil, Patrick C N Rensen, Jonathan R Ruiz, Borja Martinez-Tellez
Plasma Levels of Omega-3 and Omega-6 Derived Oxylipins Are Associated with Fecal Microbiota Composition in Young Adults. Nutrients 14 (23) (2022)
Milena Schönke, Zhixiong Ying, Artemiy Kovynev, Wietse In Het Panhuis, Anne Binnendijk, Sabine van der Poel, Amanda C M Pronk, Trea C M Streefland, Menno Hoekstra, Sander Kooijman, Patrick C N Rensen
Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (1) (2022)
Wieneke Dijk, Mathilde Di Filippo, Sander Kooijman, Robin van Eenige, Antoine Rimbert, Amandine Caillaud, Aurélie Thedrez, Lucie Arnaud, Amanda Pronk, Damien Garçon, Thibaud Sotin, Pierre Lindenbaum, Enrique Ozcariz Garcia, Jean-Paul Pais de Barros, Laurence Duvillard, Karim Si-Tayeb, Nuria Amigo, Jean-Yves Le Questel, Patrick C N Rensen, Cédric Le May, Philippe Moulin, Bertrand Cariou
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia. Circulation 146 (10) (2022)
Maaike E Straat, Borja Martinez-Tellez, Huub J van Eyk, Maurice B Bizino, Suzanne van Veen, Eleonora Vianello, Rinke Stienstra, Tom H M Ottenhoff, Hildo J Lamb, Johannes W A Smit, Ingrid M Jazet, Patrick C N Rensen, Mariëtte R Boon
Differences in inflammatory pathways between Dutch South Asians versus Dutch Europids with type 2 diabetes. The Journal of clinical endocrinology and metabolism (2022)
Borja Martinez-Tellez, Guillermo Sanchez-Delgado, Francisco M Acosta, Juan M A Alcantara, Francisco J Amaro-Gahete, Wendy D Martinez-Avila, Elisa Merchan-Ramirez, Victoria Muñoz-Hernandez, Francisco J Osuna-Prieto, Lucas Jurado-Fasoli, Huiwen Xu, Lourdes Ortiz-Alvarez, Maria Jose Arias-Tellez, Andrea Mendez-Gutierrez, Idoia Labayen Goñi, Francisco B Ortega, Milena Schönke, Patrick C N Rensen, Concepcion Maria Aguilera, José Manuel Llamas-Elvira, Ángel Gil, Jonathan R Ruiz
No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized controlled trial. Nature communications 13 (1) (2022)
Antoine Rimbert, Ming Wai Yeung, Nawar Dalila, Chris H L Thio, Haojie Yu, Natalia Loaiza, Federico Oldoni, Adriaan van der Graaf, Siqi Wang, M Abdullah Said, Lisanne L Blauw, Aurore Girardeau, Lise Bray, Amandine Caillaud, Vincent W Bloks, Marie Marrec, Philippe Moulin, Patrick C N Rensen, Bart van de Sluis, Harold Snieder, Mathilde Di Filippo, Pim van der Harst, Anne Tybjaerg-Hansen, Philip Zimmerman, Bertrand Cariou, Jan Albert Kuivenhoven
Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile. Arteriosclerosis, thrombosis, and vascular biology 42 (10) (2022)
Yared Paalvast, Enchen Zhou, Yvonne J W Rozendaal, Yanan Wang, Albert Gerding, Theo H van Dijk, Jan Freark de Boer, Patrick C N Rensen, Ko Willems van Dijk, Jan A Kuivenhoven, Barbara M Bakker, Natal van Riel, Albert K Groen
A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding. Nutrients 14 (22) (2022)
Milena Schönke, Zhixiong Ying, Artemiy Kovynev, Wietse In Het Panhuis, Anne Binnendijk, Sabine van der Poel, Amanda C M Pronk, Trea C M Streefland, Menno Hoekstra, Sander Kooijman, Patrick C N Rensen
Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (1) (2022)
Zhixiong Ying, Naomi Tramper, Enchen Zhou, Mariëtte R Boon, Patrick C N Rensen, Sander Kooijman
Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans. Cardiovascular research (2022)
Julio Madrigal-Matute, Jenny de Bruijn, Kim van Kuijk, Dario F Riascos-Bernal, Antonio Diaz, Inmaculada Tasset, Adrián Martín-Segura, Marion J J Gijbels, Bianca Sander, Susmita Kaushik, Erik A L Biessen, Simoni Tiano, Mathieu Bourdenx, Gregory J Krause, Ian McCracken, Andrew H Baker, Han Jin, Nicholas E S Sibinga, Jose Javier Bravo-Cordero, Fernando Macian, Rajat Singh, Patrick C N Rensen, Jimmy F P Berbée, Gerard Pasterkamp, Judith C Sluimer, Ana Maria Cuervo
Protective role of chaperone-mediated autophagy against atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America 119 (14) (2022)
Saeed Katiraei, Janna A van Diepen, Luciana Pádua Tavares, Lisa R Hoving, Amanda Pronk, Ineke Verschueren, Patrick C N Rensen, Jaap Jan Zwaginga, Sarantos Kostidis, Martin A Giera, Mauro Teixera, Ko Willems van Dijk, Mihai M Netea, Jimmy F P Berbée, Vanessa van Harmelen
Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes. Scientific reports 12 (1) (2022)
Francisco J Osuna-Prieto, Borja Martinez-Tellez, Lourdes Ortiz-Alvarez, Xinyu Di, Lucas Jurado-Fasoli, Huiwen Xu, Victoria Ceperuelo-Mallafré, Catalina Núñez-Roa, Isabelle Kohler, Antonio Segura Carretero, José V García-Lario, Ángel Gil, Concepcion Maria Aguilera, José Manuel Llamas-Elvira, Patrick C N Rensen, Joan Josep Vendrell, Jonathan R Ruiz, Sonia Fernández-Veledo
Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults. Cardiovascular diabetology 20 (1) (2021)
Maaike Schilperoort, Jan Kroon, Sander Kooijman, Annelies E Smit, Max Gentenaar, Kathrin Mletzko, Felix Nikolai Schmidt, Leo van Ruijven, Björn Busse, Alberto M Pereira, Natasha M Appelman-Dijkstra, Nathalie Bravenboer, Patrick C N Rensen, Onno C Meijer, Elizabeth M Winter
Loss of glucocorticoid rhythm induces an osteoporotic phenotype in female mice. Aging cell 20 (10) (2021)
Xiao-Lan Wang, Sander Kooijman, Yuanqing Gao, Laura Tzeplaeff, Brigitte Cosquer, Irina Milanova, Samantha E C Wolff, Nikita Korpel, Marie-France Champy, Benoit Petit-Demoulière, Isabelle Goncalves Da Cruz, Tania Sorg-Guss, Patrick C N Rensen, Jean-Christophe Cassel, Andries Kalsbeek, Anne-Laurence Boutillier, Chun-Xia Yi
Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity. Molecular psychiatry (2021)
Lisanne L Blauw, Raymond Noordam, Sander W van der Laan, Stella Trompet, Sander Kooijman, Diana van Heemst, Johan Wouter Jukema, Jessica van Setten, Gert J de Borst, Anne Tybjærg-Hansen, Gerard Pasterkamp, Jimmy F P Berbée, Patrick C N Rensen
Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes. Journal of clinical medicine 10 (5) (2021)
Benjamin Burggraaf, Nadine M C Pouw, Salvador Fernández Arroyo, Leonie C van Vark-van der Zee, Gert-Jan M van de Geijn, Erwin Birnie, Jeannine Huisbrink, Ellen M van der Zwan, Monique T Mulder, Patrick C N Rensen, Wouter W de Herder, Manuel Castro Cabezas
A placebo-controlled proof-of-concept study of alirocumab on postprandial lipids and vascular elasticity in insulin-treated patients with type 2 diabetes mellitus. Diabetes, obesity & metabolism 22 (5) (2020)
Maxime M Bos, Diana van Heemst, Esther Donga, Renée de Mutsert, Frits R Rosendaal, Gerard Jan Blauw, Patrick C N Rensen, Nienke R Biermasz, Raymond Noordam
The Association between Habitual Sleep Duration and Sleep Quality with Glycemic Traits: Assessment by Cross-Sectional and Mendelian Randomization Analyses. Journal of clinical medicine 8 (5) (2019)
Raymond Noordam, Maxime M Bos, Heming Wang, Thomas W Winkler, Amy R Bentley, Tuomas O Kilpeläinen, Paul S de Vries, Yun Ju Sung, Karen Schwander, Brian E Cade, Alisa K Manning, Hugues Aschard, Michael R Brown, Han Chen, Nora Franceschini, Solomon K Musani, Melissa A Richard, Dina Vojinovic, Stella Aslibekyan, Traci M Bartz, Lisa de Las Fuentes, Mary F Feitosa, Andrea R Horimoto, Marjan Ilkov, Minjung Kho, Aldi Kraja, Changwei Li, Elise Lim, Yongmei Liu, Dennis O Mook-Kanamori, Tuomo Rankinen, Salman M Tajuddin, Ashley van der Spek, Zhe Wang, Jonathan Marten, Vincent Laville, Maris Alver, Evangelos Evangelou, Maria E Graff, Meian He, Brigitte Kühnel, Leo-Pekka Lyytikainen, Pedro-Manuel Marques-Vidal, Ilja Maria Nolte, Nicholette D D Allred, Rainer Rauramaa, Xiao-Ou Shu, Harold Snieder, Stefan Weiss, Wanqing Wen, Lisa R Yanek, Adolfo Correa, Christie Ballantyne, Larry Bielak, Nienke R Biermasz, Eric Boerwinkle, Niki L Dimou, Gudny Eiriksdottir, Chuan Gao, Sina A Gharib, Daniel J Gottlieb, José Haba-Rubio, Tamara B Harris, Sami Heikkinen, Raphaël Heinzer, James E Hixson, Georg Homuth, Mohammad Arfan Ikram, Pirjo Komulainen, Jose Eduardo Krieger, Jiwon Lee, Jingmin Liu, Kurt K Lohman, Annemarie I Luik, Reedik Mägi, Lisa Warsinger Martin, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Mike A Nalls, Jeff O'Connell, Annette Peters, Patricia Peyser, Olli T Raitakari, Alex P Reiner, Patrick C N Rensen, Treva K Rice, Stephen S Rich, Till Roenneberg, Jerome I Rotter, Pamela J Schreiner, James Shikany, Stephen S Sidney, Mario Sims, Colleen M Sitlani, Tamar Sofer, Konstantin Strauch, Morris A Swertz, Kent D Taylor, Andre G Uitterlinden, Cornelia M van Duijn, Henry Völzke, Melanie Waldenberger, Robert B Wallance, Ko Willems van Dijk, Caizheng Yu, Alan B Zonderman, Diane M Becker, Paul Elliott, Tõnu Esko, Christian Gieger, Hans Jörgen Grabe, Timo A Lakka, Terho Lehtimäki, Kari E North, Brenda W J H Penninx, Peter Vollenweider, Lynne E Wagenknecht, Tangchun Wu, Yong-Bing Xiang, Quan Long, Donna K Arnett, Claude Bouchard, Michele K Evans, Vilmundur G Gudnason, Sharon Kardia, Tanika N Kelly, Stephen B Kritchevsky, Ruth J F Loos, Alexandre C Pereira, Mike Province, Bruce M Psaty, Charles Rotimi, Xiaofeng Zhu, Najaf Amin, L Adrienne Cupples, Myriam Fornage, Ervin F Fox, Xiuqing Guo, W James Gauderman, Kenneth Rice, Charles Kooperberg, Patricia B Munroe, Ching-Ti Liu, Alanna C Morrison, Dabeeru C Rao, Diana van Heemst, Susan Redline
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Nature communications 10 (1) (2019)
Anna Worthmann, Christian Schlein, Jimmy F P Berbée, Patrick C N Rensen, Joerg Heeren, Alexander Bartelt
Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression. Nutrients 11 (2) (2019)
Frank Vrieling, Louis Wilson, Patrick C N Rensen, Katharina Ronacher, Tom H M Ottenhoff, Simone A Joosten
Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction. PLoS pathogens 15 (4) (2019)
Maaike Schilperoort, Rosa van den Berg, Martijn E T Dollé, Conny T M van Oostrom, Karina Wagner, Lauren L Tambyrajah, Paul Wackers, Tom Deboer, Gerben Hulsegge, Karin I Proper, Harry van Steeg, Till Roenneberg, Nienke R Biermasz, Patrick C N Rensen, Sander Kooijman, Linda W M van Kerkhof
Time-restricted feeding improves adaptation to chronically alternating light-dark cycles. Scientific reports 9 (1) (2019)
Laura G M Janssen, Matti S Jauhiainen, Vesa M Olkkonen, P A Nidhina Haridas, Kimberly J Nahon, Patrick C N Rensen, Mariëtte R Boon
Short-Term Cooling Increases Plasma ANGPTL3 and ANGPTL8 in Young Healthy Lean Men but Not in Middle-Aged Men with Overweight and Prediabetes. Journal of clinical medicine 8 (8) (2019)
Andreas Paulus, Natascha Drude, Emmani B M Nascimento, Eva M Buhl, Jimmy F P Berbée, Patrick C N Rensen, Wouter D van Marken Lichtenbelt, Felix M Mottaghy, Matthias Bauwens
[18F]BODIPY-triglyceride-containing chylomicron-like particles as an imaging agent for brown adipose tissue in vivo. Scientific reports 9 (1) (2019)
Huub J van Eyk, Lisanne L Blauw, Maurice B Bizino, Yanan Wang, Ko Willems van Dijk, Renée de Mutsert, Johannes W A Smit, Hildo J Lamb, Ingrid M Jazet, Patrick C N Rensen
Hepatic triglyceride content does not affect circulating CETP: lessons from a liraglutide intervention trial and a population-based cohort. Scientific reports 9 (1) (2019)
Kathrin Thiem, Geerte Hoeke, Susan van den Berg, Anneke Hijmans, Cor W M Jacobs, Enchen Zhou, Isabel M Mol, Maria Mouktaroudi, Johan Bussink, Thirumala D Kanneganti, Esther Lutgens, Rinke Stienstra, Cees J Tack, Mihai M Netea, Patrick C N Rensen, Jimmy F P Berbée, Janna A van Diepen
Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice. Scientific reports 9 (1) (2019)
Maaike Schilperoort, Rosa van den Berg, Laura A Bosmans, Bram W van Os, Martijn E T Dollé, Noortje A M Smits, Teun Guichelaar, Debbie van Baarle, Lotte Koemans, Jimmy F P Berbée, Tom de Boer, Johanna H Meijer, Margreet R de Vries, Dianne Vreeken, Janine M van Gils, Ko Willems van Dijk, Linda Wilhelmina Maria van Kerkhof, Esther Lutgens, Nienke R Biermasz, Patrick C N Rensen, Sander Kooijman
Disruption of circadian rhythm by alternating light-dark cycles aggravates atherosclerosis development in APOE*3-Leiden.CETP mice. Journal of pineal research 68 (1) (2019)
Ntsiki M Held, Eline N Kuipers, Michel van Weeghel, Jan Bert van Klinken, Simone W Denis, Marc Lombès, Ronald J Wanders, Frédéric M Vaz, Patrick C N Rensen, Arthur J Verhoeven, Mariëtte R Boon, Riekelt H L Houtkooper
Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation. Scientific reports 8 (1) (2018)
Lisanne L Blauw, Raymond Noordam, Sebastian Soidinsalo, C Alexander Blauw, Ruifang Li-Gao, Renée de Mutsert, Jimmy F P Berbée, Yanan Wang, Diana van Heemst, Frits R Rosendaal, Johan Wouter Jukema, Dennis O Mook-Kanamori, Peter Würtz, Ko Willems van Dijk, Patrick C N Rensen
Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile. European journal of human genetics : EJHG 27 (3) (2018)
Eline N Kuipers, Andrea D van Dam, Dov B Ballak, Ellemiek A de Wit, Charles A Dinarello, Rinke Stienstra, Janna A van Diepen, Patrick C N Rensen, Mariëtte R Boon
IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake. International journal of molecular sciences 19 (8) (2018)
Borja Martinez-Tellez, Guillermo-Sánchez Delgado, Juan M A Alcantara, Francisco M Acosta, Francisco José Amaro-Gahete, Francisco J Osuna-Prieto, Alejandro Pérez-Bey, David Jiménez Pavón, José Manuel Llamas-Elvira, Ángel Gil, Concepcion Maria Aguilera, Patrick C N Rensen, Jonathan R Ruiz
Evidence of high 18 F-fluorodeoxyglucose uptake in the subcutaneous adipose tissue of the dorsocervical area in young adults. Experimental physiology 104 (2) (2018)
Borja Martinez-Tellez, Kimberly J Nahon, Guillermo Sanchez-Delgado, Gustavo Abreu-Vieira, Jose M Llamas-Elvira, Floris H P van Velden, Lenka M Pereira Arias-Bouda, Patrick C N Rensen, Mariëtte R Boon, Jonatan R Ruiz
The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults. Scientific reports 8 (1) (2018)
Dicky L Tahapary, Karin de Ruiter, Farid Kurniawan, Yenny Djuardi, Yanan Wang, Siti M E Nurdin, Elisa Iskandar, Dominggus Minggu, Em Yunir, Bruno Guigas, Taniawati Supali, Patrick C N Rensen, Erliyani Sartono, Pradana Soewondo, Dante S Harbuwono, Johannes W A Smit, Maria M Yazdanbakhsh
Impact of rural-urban environment on metabolic profile and response to a 5-day high-fat diet. Scientific reports 8 (1) (2018)
Yvonne J W Rozendaal, Yanan Wang, Yared Paalvast, Lauren L Tambyrajah, Zhuang Li, Ko Willems van Dijk, Patrick C N Rensen, Jan A Kuivenhoven, Albert K Groen, Peter A J Hilbers, Natal van Riel
In vivo and in silico dynamics of the development of Metabolic Syndrome. PLoS computational biology 14 (6) (2018)
Borja Martinez-Tellez, Guillermo Sanchez-Delgado, Francisco M Acosta, Juan M A Alcantara, Mariëtte R Boon, Patrick C N Rensen, Jonatan R Ruiz
Differences between the most used equations in BAT-human studies to estimate parameters of skin temperature in young lean men. Scientific reports 7 (1) (2017)
Vasudev Kantae, Kimberly J Nahon, Maaike E Straat, Leontine E H Bakker, Amy C Harms, Mario van der Stelt, Thomas Hankemeier, Ingrid M Jazet, Mariëtte R Boon, Patrick C N Rensen
Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men. Scientific reports 7 (1) (2017)