Florian R Greten

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Venues

Nature reviews. Gastroenterology & hepatology

EMBO reports

Science advances

Nature cell biology

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus

Germany

Scientific Director

Publications

Yoshinori Kagawa, J Joshua Smith, Emmanouil Fokas, Jun Watanabe, Andrea Cercek, Florian R Greten, Hideaki Bando, Qian Shi, Julio Garcia-Aguilar, Paul B Romesser, Natally Horvat, Hanna Sanoff, William Hall, Takeshi Kato, Claus Rödel, Arvind N Dasari, Takayuki Yoshino
Future direction of total neoadjuvant therapy for locally advanced rectal cancer. Nature reviews. Gastroenterology & hepatology 21 (6) (2024)
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Ruthger van Roey, Mohammed H Mosa, Anne Hartebrodt, Yussuf Hajjaj, Ana Clavel Ezquerra, Manoj K Selvaraju, Carol I Geppert, Stefanie Bärthel, Dieter Saur, Florian R Greten, Simone Brabletz, David B Blumenthal, Andreas Weigert, Thomas Brabletz, Henner F Farin, Marc P Stemmler
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer. EMBO reports 25 (8) (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Ruthger van Roey, Mohammed H Mosa, Anne Hartebrodt, Yussuf Hajjaj, Ana Clavel Ezquerra, Manoj K Selvaraju, Carol I Geppert, Stefanie Bärthel, Dieter Saur, Florian R Greten, Simone Brabletz, David B Blumenthal, Andreas Weigert, Thomas Brabletz, Henner F Farin, Marc P Stemmler
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer. EMBO reports 25 (8) (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Ruthger van Roey, Mohammed H Mosa, Anne Hartebrodt, Yussuf Hajjaj, Ana Clavel Ezquerra, Manoj K Selvaraju, Carol I Geppert, Stefanie Bärthel, Dieter Saur, Florian R Greten, Simone Brabletz, David B Blumenthal, Andreas Weigert, Thomas Brabletz, Henner F Farin, Marc P Stemmler
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer. EMBO reports 25 (8) (2024)
Yoshinori Kagawa, J Joshua Smith, Emmanouil Fokas, Jun Watanabe, Andrea Cercek, Florian R Greten, Hideaki Bando, Qian Shi, Julio Garcia-Aguilar, Paul B Romesser, Natally Horvat, Hanna Sanoff, William Hall, Takeshi Kato, Claus Rödel, Arvind N Dasari, Takayuki Yoshino
Future direction of total neoadjuvant therapy for locally advanced rectal cancer. Nature reviews. Gastroenterology & hepatology 21 (6) (2024)
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Ruthger van Roey, Mohammed H Mosa, Anne Hartebrodt, Yussuf Hajjaj, Ana Clavel Ezquerra, Manoj K Selvaraju, Carol I Geppert, Stefanie Bärthel, Dieter Saur, Florian R Greten, Simone Brabletz, David B Blumenthal, Andreas Weigert, Thomas Brabletz, Henner F Farin, Marc P Stemmler
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer. EMBO reports 25 (8) (2024)
Yoshinori Kagawa, J Joshua Smith, Emmanouil Fokas, Jun Watanabe, Andrea Cercek, Florian R Greten, Hideaki Bando, Qian Shi, Julio Garcia-Aguilar, Paul B Romesser, Natally Horvat, Hanna Sanoff, William Hall, Takeshi Kato, Claus Rödel, Arvind N Dasari, Takayuki Yoshino
Future direction of total neoadjuvant therapy for locally advanced rectal cancer. Nature reviews. Gastroenterology & hepatology 21 (6) (2024)
Yoshinori Kagawa, J Joshua Smith, Emmanouil Fokas, Jun Watanabe, Andrea Cercek, Florian R Greten, Hideaki Bando, Qian Shi, Julio Garcia-Aguilar, Paul B Romesser, Natally Horvat, Hanna Sanoff, William Hall, Takeshi Kato, Claus Rödel, Arvind N Dasari, Takayuki Yoshino
Future direction of total neoadjuvant therapy for locally advanced rectal cancer. Nature reviews. Gastroenterology & hepatology (2024)
Yoshinori Kagawa, J Joshua Smith, Emmanouil Fokas, Jun Watanabe, Andrea Cercek, Florian R Greten, Hideaki Bando, Qian Shi, Julio Garcia-Aguilar, Paul B Romesser, Natally Horvat, Hanna Sanoff, William Hall, Takeshi Kato, Claus Rödel, Arvind N Dasari, Takayuki Yoshino
Future direction of total neoadjuvant therapy for locally advanced rectal cancer. Nature reviews. Gastroenterology & hepatology (2024)
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Ruthger van Roey, Mohammed H Mosa, Anne Hartebrodt, Yussuf Hajjaj, Ana Clavel Ezquerra, Manoj K Selvaraju, Carol I Geppert, Stefanie Bärthel, Dieter Saur, Florian R Greten, Simone Brabletz, David B Blumenthal, Andreas Weigert, Thomas Brabletz, Henner F Farin, Marc P Stemmler
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer. EMBO reports (2024)
Yoshinori Kagawa, J Joshua Smith, Emmanouil Fokas, Jun Watanabe, Andrea Cercek, Florian R Greten, Hideaki Bando, Qian Shi, Julio Garcia-Aguilar, Paul B Romesser, Natally Horvat, Hanna Sanoff, William Hall, Takeshi Kato, Claus Rödel, Arvind N Dasari, Takayuki Yoshino
Future direction of total neoadjuvant therapy for locally advanced rectal cancer. Nature reviews. Gastroenterology & hepatology 21 (6) (2024)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Claire Conche, Fabian Finkelmeier, Marina Pešić, Adele M Nicolas, Tim W Böttger, Kilian B Kennel, Dominic Denk, Fatih Ceteci, Kathleen Mohs, Esther Engel, Özge Canli, Yasamin Dabiri, Kai-Hendrik Peiffer, Stefan Zeuzem, Gabriela Salinas, Thomas Longerich, Huan Yang, Florian R Greten
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade. Gut (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Henner F Farin, Mohammed H Mosa, Benardina Ndreshkjana, Britta Moyo Grebbin, Birgit Ritter, Constantin Menche, Kilian B Kennel, Paul K Ziegler, Lili Szabo, Julia Bollrath, Dietmar Rieder, Birgitta E Michels, Alena Kress, Muge Bozlar, Tahmineh Darvishi, Sara Stier, Ivan-Maximiliano Kur, Katrin Bankov, Rebecca Kesselring, Stefan Fichtner-Feigl, Bernhard Brüne, Thorsten O Goetze, Salah-Eddin Al-Batran, Christian H Brandts, Wolf Otto Bechstein, Peter J Wild, Andreas Weigert, Susanne Müller, Stefan Knapp, Zlatko Trajanoski, Florian R Greten
Colorectal cancer organoid-stroma biobank allows subtype-specific assessment of individualized therapy responses. Cancer discovery (2023)
Kilian B Kennel, Muge Bozlar, Adalbert Franciscus De Valk, Florian R Greten
Cancer-associated fibroblasts in inflammation and anti-tumor immunity. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Mark Schmitt, Fatih Ceteci, Jalaj Gupta, Marina Pesic, Tim W Böttger, Adele M Nicolas, Kilian B Kennel, Esther Engel, Matthias Schewe, Asude Callak Kirisözü, Valentina Petrocelli, Yasamin Dabiri, Julia Varga, Mallika Ramakrishnan, Madina Karimova, Andrea Ablasser, Toshiro Sato, Melek C Arkan, Frederic J de Sauvage, Florian R Greten
Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation. Nature 612 (7939) (2022)
Eiman Elwakeel, Mirko Brüggemann, Jessica Wagih, Olga Lityagina, Mohammed A F Elewa, Yingying Han, Timo Frömel, Rüdiger Popp, Adele M Nicolas, Yannick Schreiber, Elise Gradhand, Dominique Thomas, Rolf Nüsing, Julia Steinmetz-Späh, Soni Savai Pullamsetti, Emmanouil Fokas, Ingrid Fleming, Florian R Greten, Kathi Zarnack, Bernhard Brüne, Andreas Weigert
Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis. Cancer research 82 (7) (2022)
Mark Schmitt, Florian R Greten
The inflammatory pathogenesis of colorectal cancer. Nature reviews. Immunology 21 (10) (2021)
Christopher Berlin, Felicie Cottard, Dominica Willmann, Sylvia Urban, Stephan M Tirier, Lisa Marx, Karsten Rippe, Mark Schmitt, Valentina Petrocelli, Florian R Greten, Stefan Fichtner-Feigl, Rebecca Kesselring, Eric Metzger, Roland Schüle
KMT9 controls stemness and growth of colorectal cancer. Cancer research (2021)
Erik Sahai, Igor Astsaturov, Edna Cukierman, David G DeNardo, Mikala Egeblad, Ronald M Evans, Douglas Fearon, Florian R Greten, Sunil R Hingorani, Tony Hunter, Richard O Hynes, Rakesh K Jain, Tobias Janowitz, Claus Jorgensen, Alec C Kimmelman, Mikhail G Kolonin, Robert G Maki, R Scott Powers, Ellen Puré, Daniel C Ramirez, Ruth Scherz-Shouval, Mara H Sherman, Sheila A Stewart, Thea D Tlsty, David A Tuveson, Fiona M Watt, Valerie Weaver, Ashani T Weeraratna, Zena Werb
A framework for advancing our understanding of cancer-associated fibroblasts. Nature reviews. Cancer 20 (3) (2020)
Mohammed H Mosa, Birgitta E Michels, Constantin Menche, Adele M Nicolas, Tahmineh Darvishi, Florian R Greten, Henner F Farin
A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer. Cancer research 80 (24) (2020)
Jelena Todoric, Giuseppe Di Caro, Saskia Reibe, Darren C Henstridge, Courtney R Green, Alison Vrbanac, Fatih Ceteci, Claire Conche, Reginald McNulty, Shabnam Shalapour, Koji Taniguchi, Peter J Meikle, Jeramie D Watrous, Rafael Moranchel, Mahan Najhawan, Mohit Jain, Xiao Liu, Tatiana Kisseleva, Maria T Diaz-Meco, Jorge Moscat, Rob Knight, Florian R Greten, Lester F Lau, Christian M Metallo, Mark A Febbraio, Michael Karin
Fructose stimulated de novo lipogenesis is promoted by inflammation. Nature metabolism 2 (10) (2020)
Clemens Neufert, Christina Heichler, Thomas Brabletz, Kristina Koop, Verawan Boonsanay, Florian R Greten, Markus F Neurath
Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis. Nature protocols 16 (1) (2020)
Birgit Ritter, Florian R Greten
Modulating inflammation for cancer therapy. The Journal of experimental medicine 216 (6) (2019)
Tiago De Oliveira, Mallika Ramakrishnan, Michaela A Diamanti, Paul K Ziegler, Frank Brombacher, Florian R Greten
Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis. Oncogene 38 (11) (2018)
Julia Varga, Florian R Greten
Cell plasticity in epithelial homeostasis and tumorigenesis. Nature cell biology 19 (10) (2017)
Michaela A Diamanti, Jalaj Gupta, Moritz Bennecke, Tiago De Oliveira, Mallika Ramakrishnan, Anne K Braczynski, Benjamin Richter, Petra Beli, Yinling Hu, Maya Saleh, Michel Mittelbronn, Ivan Đikić, Florian R Greten
IKKα controls ATG16L1 degradation to prevent ER stress during inflammation. The Journal of experimental medicine 214 (2) (2017)
Sjoerd J L van Wijk, Franziska Fricke, Lina Herhaus, Jalaj Gupta, Katharina Hötte, Francesco Pampaloni, Paolo Grumati, Manuel Kaulich, Yu-Shin Sou, Masaaki Komatsu, Florian R Greten, Simone Fulda, Mike Heilemann, Ivan Dikic
Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation. Nature microbiology 2 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Florian R Greten