Brent R Stockwell (Brent Stockwell)

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 68

Top Topics

Top Venues

Nature communications

Nature chemical biology

Science advances

ACS chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Peng Gao, Mitali Tambe, Catherine Z Chen, Wenwei Huang, Gregory J Tawa, Tal Hirschhorn, Brent R Stockwell, Wei Zheng, Min Shen
Identification of Potent ADCK3 Inhibitors through Structure-Based Virtual Screening. Journal of chemical information and modeling (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Matei A Banu, Athanassios Dovas, Michael G Argenziano, Wenting Zhao, Colin P Sperring, Henar Cuervo Grajal, Zhouzerui Liu, Dominique Mo Higgins, Misha Amini, Brianna Pereira, Ling F Ye, Aayushi Mahajan, Nelson Humala, Julia L Furnari, Pavan S Upadhyayula, Fereshteh Zandkarimi, Trang Thi Thu Nguyen, Damian Teasley, Peter B Wu, Li Hai, Charles Karan, Tyrone Dowdy, Aida Razavilar, Markus D Siegelin, Jan Kitajewski, Mioara Larion, Jeffrey N Bruce, Brent R Stockwell, Peter A Sims, Peter D Canoll
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. The EMBO journal (2024)
Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi, Candace D Castagna, Hui Tan, Miroslav Sekulic, Lisa Miorin, Hanina Hibshoosh, Shinya Toyokuni, Koji Uchida, Brent R Stockwell
Fatal COVID-19 pulmonary disease involves ferroptosis. Nature communications 15 (1) (2024)
Raphaël Rodriguez, Tatiana Cañeque, Leeroy Baron, Sebastian Muller, Alanis Carmona, Ludovic Colombeau, Antoine Versini, Marie Sabatier, Julio Sampaio, Eikan Mishima, Armel Picard-Bernes, Stéphanie Solier, Jiashuo Zheng, Bettina Proneth, Leishemba Thoidingjam, Christine Gaillet, Laurence Grimaud, Cameron S Fraser, Krystina Szylo, Caroline Bonnet, Emmanuelle Charafe, Christophe Ginestier, Patricia Santofimia, Nelson J Dusetti, Juan Lucio Iovanna, Antonio Sa Cunha, Gabriella Pittau, Pascal Hammel, Dimitri Tzanis, Sylvie Bonvalot, Sarah Watson, Brent R Stockwell, Marcus Conrad, Jessalyn M Ubellacker
Activation of lysosomal iron triggers ferroptosis in cancer. Research square (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi, Candace D Castagna, Hui Tan, Miroslav Sekulic, Lisa Miorin, Hanina Hibshoosh, Shinya Toyokuni, Koji Uchida, Brent R Stockwell
Fatal COVID-19 pulmonary disease involves ferroptosis. Nature communications 15 (1) (2024)
Xiaoguang Liu, Zhen Chen, Yuelong Yan, Fereshteh Zandkarimi, Litong Nie, Qidong Li, Amber D Horbath, Kellen Olszewski, Lavanya Kondiparthi, Chao Mao, Hyemin Lee, Li Zhuang, Masha V Poyurovsky, Brent R Stockwell, Junjie Chen, Boyi Gan
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis. Protein & cell 15 (9) (2024)
Raphaël Rodriguez, Tatiana Cañeque, Leeroy Baron, Sebastian Muller, Alanis Carmona, Ludovic Colombeau, Antoine Versini, Marie Sabatier, Julio Sampaio, Eikan Mishima, Armel Picard-Bernes, Stéphanie Solier, Jiashuo Zheng, Bettina Proneth, Leishemba Thoidingjam, Christine Gaillet, Laurence Grimaud, Cameron S Fraser, Krystina Szylo, Caroline Bonnet, Emmanuelle Charafe, Christophe Ginestier, Patricia Santofimia, Nelson J Dusetti, Juan Lucio Iovanna, Antonio Sa Cunha, Gabriella Pittau, Pascal Hammel, Dimitri Tzanis, Sylvie Bonvalot, Sarah Watson, Brent R Stockwell, Marcus Conrad, Jessalyn M Ubellacker
Activation of lysosomal iron triggers ferroptosis in cancer. Research square (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Matei A Banu, Athanassios Dovas, Michael G Argenziano, Wenting Zhao, Colin P Sperring, Henar Cuervo Grajal, Zhouzerui Liu, Dominique Mo Higgins, Misha Amini, Brianna Pereira, Ling F Ye, Aayushi Mahajan, Nelson Humala, Julia L Furnari, Pavan S Upadhyayula, Fereshteh Zandkarimi, Trang Thi Thu Nguyen, Damian Teasley, Peter B Wu, Li Hai, Charles Karan, Tyrone Dowdy, Aida Razavilar, Markus D Siegelin, Jan Kitajewski, Mioara Larion, Jeffrey N Bruce, Brent R Stockwell, Peter A Sims, Peter D Canoll
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. The EMBO journal (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Enyong Dai, Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E Kagan, Hülya Bayir, Wan Seok Yang, Ana J Garcia-Saez, Maria S Ioannou, Tobias Janowitz, Qitao Ran, Wei Gu, Boyi Gan, Dmitri V Krysko, Xiao-Feng Zhu, Jiayi Wang, Stefan Krautwald, Shinya Toyokuni, Yangchun Xie, Florian R Greten, Qing Yi, Joel A Schick, Jiao Liu, Dmitry I Gabrilovich, Jin-Bao Liu, Herbert J Zeh, Donna D Zhang, Minghua Yang, Juan Iovanna, Manfred Kopf, Timon Erik Adolph, Jen-Tsan Chi, Changfeng Li, Hidenori Ichijo, Michael Karin, Vijay G Sankaran, Weiping Zou, Lorenzo Galluzzi, Ashley I Bush, Binghui Li, Gerry Melino, Eric H Baehrecke, Michael T Lotze, Daniel J Klionsky, Brent R Stockwell, Guido Kroemer, Daolin Tang
A guideline on the molecular ecosystem regulating ferroptosis. Nature cell biology (2024)
Juliane Tschuck, Vidya Padmanabhan Nair, Ana Galhoz, Carole Zaratiegui, Hin-Man Tai, Gabriele Ciceri, Ina Rothenaigner, Jason Tchieu, Brent R Stockwell, Lorenz Studer, Daphne S Cabianca, Michael Patrick Menden, Michelle Vincendeau, Kamyar Hadian
Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development. Nature communications 15 (1) (2024)
Peng Gao, Mitali Tambe, Catherine Z Chen, Wenwei Huang, Gregory J Tawa, Tal Hirschhorn, Brent R Stockwell, Wei Zheng, Min Shen
Identification of Potent ADCK3 Inhibitors through Structure-Based Virtual Screening. Journal of chemical information and modeling 64 (15) (2024)
Xiaoguang Liu, Zhen Chen, Yuelong Yan, Fereshteh Zandkarimi, Litong Nie, Qidong Li, Amber D Horbath, Kellen Olszewski, Lavanya Kondiparthi, Chao Mao, Hyemin Lee, Li Zhuang, Masha V Poyurovsky, Brent R Stockwell, Junjie Chen, Boyi Gan
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis. Protein & cell 15 (9) (2024)
Peng Gao, Mitali Tambe, Catherine Z Chen, Wenwei Huang, Gregory J Tawa, Tal Hirschhorn, Brent R Stockwell, Wei Zheng, Min Shen
Identification of Potent ADCK3 Inhibitors through Structure-Based Virtual Screening. Journal of chemical information and modeling 64 (15) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi, Candace D Castagna, Hui Tan, Miroslav Sekulic, Lisa Miorin, Hanina Hibshoosh, Shinya Toyokuni, Koji Uchida, Brent R Stockwell
Fatal COVID-19 pulmonary disease involves ferroptosis. Nature communications 15 (1) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Zhe Wang, Xin Yang, Delin Chen, Yanqing Liu, Zhiming Li, Shoufu Duan, Zhiguo Zhang, Xuejun Jiang, Brent R Stockwell, Wei Gu
GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature communications 15 (1) (2024)
Kamyar Hadian, Brent R Stockwell
The therapeutic potential of targeting regulated non-apoptotic cell death. Nature reviews. Drug discovery (2023)
Annadurai Anandhan, Matthew Dodson, Aryatara Shakya, Jinjing Chen, Pengfei Liu, Yongyi Wei, Hui Tan, Qian Wang, Ziyan Jiang, Kevin Yang, Joe G N Garcia, Setsuko K Chambers, Eli Chapman, Aikseng Ooi, Yang Yang-Hartwich, Brent R Stockwell, Donna D Zhang
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Science advances 9 (5) (2023)
Nailah Smith, Eduard Reznik, Brygida Bisikirska, Vasiliki Polychronidou, Qian Wang, Arie Zask, Farhad Forouhar, Andrea Califano, Brent R Stockwell
Kinases Controlling Stability of the Oncogenic MYCN Protein. ACS medicinal chemistry letters 14 (12) (2023)
Pavan S Upadhyayula, Dominique M Higgins, Angeliki Mela, Matei Banu, Athanassios Dovas, Fereshteh Zandkarimi, Purvi Patel, Aayushi Mahajan, Nelson Humala, Trang Thi Thu Nguyen, Kunal R Chaudhary, Lillian Liao, Michael Argenziano, Tejaswi Sudhakar, Colin P Sperring, Benjamin L Shapiro, Eman R Ahmed, Connor Kinslow, Ling F Ye, Markus D Siegelin, Simon Cheng, Rajesh Soni, Jeffrey N Bruce, Brent R Stockwell, Peter D Canoll
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature communications 14 (1) (2023)
Matei A Banu, Athanassios Dovas, Michael G Argenziano, Wenting Zhao, Henar Cuervo Grajal, Dominique M O Higgins, Colin P Sperring, Brianna Pereira, Ling F Ye, Aayushi Mahajan, Nelson Humala, Julia L Furnari, Pavan S Upadhyayula, Fereshteh Zandkarimi, Trang T T Nguyen, Peter B Wu, Li Hai, Charles Karan, Aida Razavilar, Markus D Siegelin, Jan Kitajewski, Jeffrey N Bruce, Brent R Stockwell, Peter A Sims, Peter D Canoll
A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. bioRxiv : the preprint server for biology (2023)
Matei A Banu, Athanassios Dovas, Michael G Argenziano, Wenting Zhao, Henar Cuervo Grajal, Dominique M O Higgins, Colin P Sperring, Brianna Pereira, Ling F Ye, Aayushi Mahajan, Nelson Humala, Julia L Furnari, Pavan S Upadhyayula, Fereshteh Zandkarimi, Trang T T Nguyen, Peter B Wu, Li Hai, Charles Karan, Aida Razavilar, Markus D Siegelin, Jan Kitajewski, Jeffrey N Bruce, Brent R Stockwell, Peter A Sims, Peter D Canoll
A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. bioRxiv : the preprint server for biology (2023)
Annadurai Anandhan, Matthew Dodson, Aryatara Shakya, Jinjing Chen, Pengfei Liu, Yongyi Wei, Hui Tan, Qian Wang, Ziyan Jiang, Kevin Yang, Joe G N Garcia, Setsuko K Chambers, Eli Chapman, Aikseng Ooi, Yang Yang-Hartwich, Brent R Stockwell, Donna D Zhang
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Science advances 9 (5) (2023)
Pavan S Upadhyayula, Dominique M Higgins, Angeliki Mela, Matei Banu, Athanassios Dovas, Fereshteh Zandkarimi, Purvi Patel, Aayushi Mahajan, Nelson Humala, Trang Thi Thu Nguyen, Kunal R Chaudhary, Lillian Liao, Michael Argenziano, Tejaswi Sudhakar, Colin P Sperring, Benjamin L Shapiro, Eman R Ahmed, Connor Kinslow, Ling F Ye, Markus D Siegelin, Simon Cheng, Rajesh Soni, Jeffrey N Bruce, Brent R Stockwell, Peter D Canoll
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature communications 14 (1) (2023)
Pavan S Upadhyayula, Dominique M Higgins, Angeliki Mela, Matei Banu, Athanassios Dovas, Fereshteh Zandkarimi, Purvi Patel, Aayushi Mahajan, Nelson Humala, Trang Thi Thu Nguyen, Kunal R Chaudhary, Lillian Liao, Michael Argenziano, Tejaswi Sudhakar, Colin P Sperring, Benjamin L Shapiro, Eman R Ahmed, Connor Kinslow, Ling F Ye, Markus D Siegelin, Simon Cheng, Rajesh Soni, Jeffrey N Bruce, Brent R Stockwell, Peter D Canoll
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature communications 14 (1) (2023)
Pavan S Upadhyayula, Dominique M Higgins, Angeliki Mela, Matei Banu, Athanassios Dovas, Fereshteh Zandkarimi, Purvi Patel, Aayushi Mahajan, Nelson Humala, Trang Thi Thu Nguyen, Kunal R Chaudhary, Lillian Liao, Michael Argenziano, Tejaswi Sudhakar, Colin P Sperring, Benjamin L Shapiro, Eman R Ahmed, Connor Kinslow, Ling F Ye, Markus D Siegelin, Simon Cheng, Rajesh Soni, Jeffrey N Bruce, Brent R Stockwell, Peter D Canoll
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature communications 14 (1) (2023)
Ellen M Quardokus, Diane C Saunders, Elizabeth McDonough, John W Hickey, Christopher Werlein, Christine Surrette, Presha Rajbhandari, Anna Martinez Casals, Hua Tian, Lisa Lowery, Elizabeth K Neumann, Frida Björklund, Taruna V Neelakantan, Joshua Croteau, Anne E Wiblin, Jeremy Fisher, April J Livengood, Karen G Dowell, Jonathan C Silverstein, Jeffrey M Spraggins, Gloria S Pryhuber, Gail Deutsch, Fiona Ginty, Garry P Nolan, Simon Melov, Danny D Jonigk, Michael A Caldwell, Ioannis S Vlachos, Werner Muller, Nils Gehlenborg, Brent R Stockwell, Emma Lundberg, Michael Paul Snyder, Ronald N Germain, Jeannie M Camarillo, Michael P Snyder, Katy Börner, Andrea J Radtke
Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging. Nature methods (2023)
Pavan S Upadhyayula, Dominique M Higgins, Angeliki Mela, Matei Banu, Athanassios Dovas, Fereshteh Zandkarimi, Purvi Patel, Aayushi Mahajan, Nelson Humala, Trang Thi Thu Nguyen, Kunal R Chaudhary, Lillian Liao, Michael Argenziano, Tejaswi Sudhakar, Colin P Sperring, Benjamin L Shapiro, Eman R Ahmed, Connor Kinslow, Ling F Ye, Markus D Siegelin, Simon Cheng, Rajesh Soni, Jeffrey N Bruce, Brent R Stockwell, Peter D Canoll
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature communications 14 (1) (2023)
Nailah Smith, Eduard Reznik, Brygida Bisikirska, Vasiliki Polychronidou, Qian Wang, Arie Zask, Farhad Forouhar, Andrea Califano, Brent R Stockwell
Kinases Controlling Stability of the Oncogenic MYCN Protein. ACS medicinal chemistry letters 14 (12) (2023)
Jingbo Li, Jiao Liu, Zhuan Zhou, Runliu Wu, Xin Chen, Chunhua Yu, Brent R Stockwell, Guido Kroemer, Rui Kang, Daolin Tang
Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer. Science translational medicine 15 (720) (2023)
Annadurai Anandhan, Matthew Dodson, Aryatara Shakya, Jinjing Chen, Pengfei Liu, Yongyi Wei, Hui Tan, Qian Wang, Ziyan Jiang, Kevin Yang, Joe G N Garcia, Setsuko K Chambers, Eli Chapman, Aikseng Ooi, Yang Yang-Hartwich, Brent R Stockwell, Donna D Zhang
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Science advances 9 (5) (2023)
Annadurai Anandhan, Matthew Dodson, Aryatara Shakya, Jinjing Chen, Pengfei Liu, Yongyi Wei, Hui Tan, Qian Wang, Ziyan Jiang, Kevin Yang, Joe G N Garcia, Setsuko K Chambers, Eli Chapman, Aikseng Ooi, Yang Yang-Hartwich, Brent R Stockwell, Donna D Zhang
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Science advances 9 (5) (2023)
Luciano Ferrada, María José Barahona, Matías Vera, Brent R Stockwell, Francisco J Nualart
Dehydroascorbic acid sensitizes cancer cells to system x c - inhibition-induced ferroptosis by promoting lipid droplet peroxidation. Cell death & disease 14 (9) (2023)
A Nikolai von Krusenstiern, Ryan N Robson, Naixin Qian, Baiyu Qiu, Fanghao Hu, Eduard Reznik, Nailah Smith, Fereshteh Zandkarimi, Verna M Estes, Marcel Dupont, Tal Hirschhorn, Mikhail S Shchepinov, Wei Min, K A Woerpel, Brent R Stockwell
Identification of essential sites of lipid peroxidation in ferroptosis. Nature chemical biology (2023)
Nailah Smith, Eduard Reznik, Brygida Bisikirska, Vasiliki Polychronidou, Qian Wang, Arie Zask, Farhad Forouhar, Andrea Califano, Brent R Stockwell
Kinases Controlling Stability of the Oncogenic MYCN Protein. ACS medicinal chemistry letters 14 (12) (2023)
Annadurai Anandhan, Matthew Dodson, Aryatara Shakya, Jinjing Chen, Pengfei Liu, Yongyi Wei, Hui Tan, Qian Wang, Ziyan Jiang, Kevin Yang, Joe G N Garcia, Setsuko K Chambers, Eli Chapman, Aikseng Ooi, Yang Yang-Hartwich, Brent R Stockwell, Donna D Zhang
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Science advances 9 (5) (2023)
Sawako Suzuki, Divya Venkatesh, Hiroaki Kanda, Akitoshi Nakayama, Hiroyuki Hosokawa, Eunyoung Lee, Takashi Miki, Brent R Stockwell, Koutaro Yokote, Tomoaki Tanaka, Carol Prives
GLS2 Is a Tumor Suppressor and a Regulator of Ferroptosis in Hepatocellular Carcinoma. Cancer research 82 (18) (2022)
Jenny Jin, Kenji Schorpp, Daniel Samaga, Kristian Unger, Kamyar Hadian, Brent R Stockwell
Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining. ACS chemical biology 17 (3) (2022)
Hengrui Liu, Sho Iketani, Arie Zask, Nisha Khanizeman, Eva Bednarova, Farhad Forouhar, Brandon Fowler, Seo Jung Hong, Hiroshi Mohri, Manoj S Nair, Yaoxing Huang, Nicholas E S Tay, Sumin Lee, Charles Karan, Samuel J Resnick, Colette Quinn, Wenjing Li, Henry Shion, Xin Xia, Jacob D Daniels, Michelle Bartolo-Cruz, Marcelo Farina, Presha Rajbhandari, Christopher Jurtschenko, Matthew A Lauber, Thomas McDonald, Michael E Stokes, Brett L Hurst, Tomislav Rovis, Alejandro Chavez, David D Ho, Brent R Stockwell
Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nature communications 13 (1) (2022)
Clara Reglero, Chelsea L Dieck, Arie Zask, Farhad Forouhar, Anouchka P Laurent, Wen-Hsuan Wendy Lin, Robert Albero, Hannah I Miller, Cindy Ma, Julie M Gastier-Foster, Mignon L Loh, Liang Tong, Brent R Stockwell, Teresa Palomero, Adolfo A Ferrando
Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia. Cancer discovery 12 (11) (2022)
Sho Iketani, Farhad Forouhar, Hengrui Liu, Seo Jung Hong, Fang-Yu Lin, Manoj S Nair, Arie Zask, Yaoxing Huang, Li Xing, Brent R Stockwell, Alejandro Chavez, David D Ho
Author Correction: Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature communications 12 (1) (2021)
Kamyar Hadian, Brent R Stockwell
A roadmap to creating ferroptosis-based medicines. Nature chemical biology 17 (11) (2021)
Sho Iketani, Farhad Forouhar, Hengrui Liu, Seo Jung Hong, Fang-Yu Lin, Manoj S Nair, Arie Zask, Yaoxing Huang, Li Xing, Brent R Stockwell, Alejandro Chavez, David D Ho
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature communications 12 (1) (2021)
Hengrui Liu, Farhad Forouhar, Tobias Seibt, Russell Saneto, Kristen Wigby, Jennifer Friedman, Xin Xia, Mikhail S Shchepinov, Sanath Kumar Ramesh, Marcus Conrad, Brent R Stockwell
Characterization of a patient-derived variant of GPX4 for precision therapy. Nature chemical biology 18 (1) (2021)
Xuejun Jiang, Brent R Stockwell, Marcus Conrad
Ferroptosis: mechanisms, biology and role in disease. Nature reviews. Molecular cell biology 22 (4) (2021)
Samuel J Resnick, Sho Iketani, Seo Jung Hong, Arie Zask, Hengrui Liu, Sungsoo Kim, Schuyler Melore, Manoj S Nair, Yaoxing Huang, Nicholas E S Tay, Tomislav Rovis, Hee Won Yang, Brent R Stockwell, David D Ho, Alejandro Chavez
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors. bioRxiv : the preprint server for biology (2020)
Ling F Ye, Kunal R Chaudhary, Fereshteh Zandkarimi, Andrew D Harken, Connor J Kinslow, Pavan S Upadhyayula, Athanassios Dovas, Dominique M Higgins, Hui Tan, Yan Zhang, Manuela Buonanno, Tony J C Wang, Tom K Hei, Jeffrey N Bruce, Peter D Canoll, Simon K Cheng, Brent R Stockwell
Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers. ACS chemical biology 15 (2) (2020)
Divya Venkatesh, Nicholas A O'Brien, Fereshteh Zandkarimi, David R Tong, Michael E Stokes, Denise E Dunn, Everett S Kengmana, Allegra T Aron, Alyssa M Klein, Joleen M Csuka, Sung-Hwan Moon, Marcus Conrad, Christopher J Chang, Donald C Lo, Angelo D'Alessandro, Carol Prives, Brent R Stockwell
MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling. Genes & development 34 (7-8) (2020)
Hyemin Lee, Fereshteh Zandkarimi, Yilei Zhang, Jitendra Kumar Meena, Jongchan Kim, Li Zhuang, Siddhartha Tyagi, Li Ma, Thomas F Westbrook, Gregory R Steinberg, Daisuke Nakada, Brent R Stockwell, Boyi Gan
Energy-stress-mediated AMPK activation inhibits ferroptosis. Nature cell biology 22 (2) (2020)
Michael A Badgley, Daniel M Kremer, Hans Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl, Amanda R Decker, Steve A Sastra, Carmine F Palermo, Leonardo R Andrade, Peter Sajjakulnukit, Li Zhang, Zachary P Tolstyka, Tal Hirschhorn, Candice Lamb, Tong Liu, Wei Gu, E Scott Seeley, Everett Stone, George Georgiou, Uri Manor, Alina Iuga, Geoffrey M Wahl, Brent R Stockwell, Costas Andreas Lyssiotis, Kenneth P Olive
Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.) 368 (6486) (2020)
Huizhong Feng, Yan Zhang, Pieter H Bos, Jennifer M Chambers, Marcel M Dupont, Brent R Stockwell
K-RasG12D Has a Potential Allosteric Small Molecule Binding Site. Biochemistry 58 (21) (2019)
Marcus Conrad, Valerian E Kagan, Hülya Bayir, Gabriela C Pagnussat, Brian Head, Maret G Traber, Brent R Stockwell
Regulation of lipid peroxidation and ferroptosis in diverse species. Genes & development 32 (9-10) (2018)
Huizhong Feng, Brent R Stockwell
Unsolved mysteries: How does lipid peroxidation cause ferroptosis? PLoS biology 16 (5) (2018)
Yan Zhang, Marie-Hélène Larraufie, Leila Musavi, Hemanth Akkiraju, Lewis M Brown, Brent R Stockwell
Design of Small Molecules That Compete with Nucleotide Binding to an Engineered Oncogenic KRAS Allele. Biochemistry 57 (8) (2018)
Carrie E Yozwiak, Tal Hirschhorn, Brent R Stockwell
Toward a Microparticle-Based System for Pooled Assays of Small Molecules in Cellular Contexts. ACS chemical biology 13 (3) (2018)
Hengrui Liu, Stuart L Schreiber, Brent R Stockwell
Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy. Biochemistry 57 (14) (2018)
Michael M Gaschler, Fanghao Hu, Huizhong Feng, Andreas Linkermann, Wei Min, Brent R Stockwell
Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis. ACS chemical biology 13 (4) (2018)
Ayelén Mariana Distéfano, María Victoria Martin, Juan Pablo Córdoba, Andrés Martín Bellido, Sebastián D'Ippólito, Silvana Lorena Colman, Débora Soto, Juan Alfredo Roldán, Carlos Guillermo Bartoli, Eduardo Julián Zabaleta, Diego Fernando Fiol, Brent R Stockwell, Scott J Dixon, Gabriela Carolina Pagnussat
Heat stress induces ferroptosis-like cell death in plants. The Journal of cell biology 216 (2) (2017)
Wan Seok Yang, Katherine J Kim, Michael M Gaschler, Milesh Patel, Mikhail S Shchepinov, Brent R Stockwell
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proceedings of the National Academy of Sciences of the United States of America 113 (34) (2016)
Kenichi Shimada, Rachid Skouta, Anna Kaplan, Wan Seok Yang, Miki Hayano, Scott J Dixon, Lewis M Brown, Carlos A Valenzuela, Adam J Wolpaw, Brent R Stockwell
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nature chemical biology 12 (7) (2016)
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