Jianming Zhu (Weiliang Zhu)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 54

Top Venues

Journal of chemical information and modeling

Journal of medicinal chemistry

Signal transduction and targeted therapy

Communications chemistry

Shanghai Institute of Materia Medica Chinese Academy of Sciences

Shanghai Institute of Materia Medica Chinese Academy of Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Shanghai Institute of Materia Medica Chinese Academy of Sciences

China

Professor, Principal Investigator :: Drug Discovery and Design Center

Singapore Polytechnic

Singapore

Visiting Lecturer, Lecturer :: Department of Chemical and Life Sciences

Education History

Shanghai Institute of Materia Medica Chinese Academy of Sciences Sep 01 1995 - Apr 25 1998

China

PHD :: Drug Discovery and Design Center

Suzhou University

China

MSC :: Department of Chemistry

Yangzhou University

China

BSC :: Department of Chemistry

Publications

Hongjian Qin, Zijian Han, Emmanuel Mintah Bonku, Haiguo Sun, Abdullajon Odilov, Fuqiang Zhu, Safomuddin Abduahadi, Jianming Zhu, Jingshan Shen, Haji Akber Aisa
Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds. Communications chemistry 7 (1) (2024)
Jintian Li, Liping Zhou, Zijian Han, Leyun Wu, Jianfang Zhang, Jianming Zhu, Zhijian Xu
Impact of Halogen Bonds on Protein-Peptide Binding and Protein Structural Stability Revealed by Computational Approaches. Journal of medicinal chemistry 67 (6) (2024)
Jintian Li, Liping Zhou, Zijian Han, Leyun Wu, Jianfang Zhang, Jianming Zhu, Zhijian Xu
Impact of Halogen Bonds on Protein-Peptide Binding and Protein Structural Stability Revealed by Computational Approaches. Journal of medicinal chemistry (2024)
Minfei Ma, Xinben Zhang, Liping Zhou, Zijian Han, Yulong Shi, Jintian Li, Leyun Wu, Zhijian Xu, Jianming Zhu
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds. Journal of chemical information and modeling 64 (3) (2024)
Minfei Ma, Xinben Zhang, Liping Zhou, Zijian Han, Yulong Shi, Jintian Li, Leyun Wu, Zhijian Xu, Jianming Zhu
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds. Journal of chemical information and modeling 64 (3) (2024)
Minfei Ma, Xinben Zhang, Liping Zhou, Zijian Han, Yulong Shi, Jintian Li, Leyun Wu, Zhijian Xu, Jianming Zhu
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds. Journal of chemical information and modeling (2024)
Minfei Ma, Xinben Zhang, Liping Zhou, Zijian Han, Yulong Shi, Jintian Li, Leyun Wu, Zhijian Xu, Jianming Zhu
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds. Journal of chemical information and modeling 64 (3) (2024)
Jintian Li, Liping Zhou, Zijian Han, Leyun Wu, Jianfang Zhang, Jianming Zhu, Zhijian Xu
Impact of Halogen Bonds on Protein-Peptide Binding and Protein Structural Stability Revealed by Computational Approaches. Journal of medicinal chemistry 67 (6) (2024)
Minfei Ma, Xinben Zhang, Liping Zhou, Zijian Han, Yulong Shi, Jintian Li, Leyun Wu, Zhijian Xu, Jianming Zhu
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds. Journal of chemical information and modeling 64 (3) (2024)
Sanfeng Dong, Hui Huang, Jintian Li, Xiaomei Li, Samuel Jacob Bunu, Yun Yang, Yong Zhang, Qi Jia, Zhijian Xu, Yingxia Li, Hu Zhou, Bo Li, Jianming Zhu
Development of ketalized unsaturated saccharides as multifunctional cysteine-targeting covalent warheads. Communications chemistry 7 (1) (2024)
Lei Li, Rui Cao, Kaixin Chen, Chunrong Qu, Kun Qian, Jia Lin, Renda Li, Chaoquan Lai, Xiao Wang, Zijian Han, Zhijian Xu, Liping Zhou, Shaoli Song, Jianming Zhu, Zhen Cheng
Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold. Bioconjugate chemistry (2024)
Hongjian Qin, Zijian Han, Emmanuel Mintah Bonku, Haiguo Sun, Abdullajon Odilov, Fuqiang Zhu, Safomuddin Abduahadi, Jianming Zhu, Jingshan Shen, Haji Akber Aisa
Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds. Communications chemistry 7 (1) (2024)
Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Jianming Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng
Development of a Novel 18 F-Labeled Probe for PET Imaging of Estrogen Receptor β. Journal of medicinal chemistry 66 (2) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Li Xu, Yingcong Wang, Guanli Wang, Shushan Guo, Dandan Yu, Qilin Feng, Ke Hu, Gege Chen, Bo Li, Zhijian Xu, Xinyan Jia, Yumeng Lu, Hui Zhang, Xuejie Gao, Shuaikang Chang, Huaping Wang, Xiaosong Wu, Dongliang Song, Guang Yang, Huabin Zhu, Jinfeng Zhou, Fenghuang Zhan, Jianming Zhu, Jumei Shi
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma. Leukemia (2023)
Liping Zhou, Jintian Li, Yulong Shi, Leyun Wu, Jianming Zhu, Zhijian Xu
Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies. Physical chemistry chemical physics : PCCP (2023)
Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Jianming Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng
Development of a Novel 18 F-Labeled Probe for PET Imaging of Estrogen Receptor β. Journal of medicinal chemistry 66 (2) (2023)
Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Jianming Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng
Development of a Novel 18 F-Labeled Probe for PET Imaging of Estrogen Receptor β. Journal of medicinal chemistry (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Jianming Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng
Development of a Novel 18 F-Labeled Probe for PET Imaging of Estrogen Receptor β. Journal of medicinal chemistry 66 (2) (2023)
Liping Zhou, Leyun Wu, Cheng Peng, Yanqing Yang, Yulong Shi, Likun Gong, Zhijian Xu, Jianming Zhu
Predicting spike protein NTD mutations of SARS-CoV-2 causing immune evasion by molecular dynamics simulations. Physical chemistry chemical physics : PCCP 24 (5) (2022)
Kaijie Mu, Zhengdan Zhu, Amina Abula, Cheng Peng, Jianming Zhu, Zhijian Xu
Halogen Bonds Exist between Noncovalent Ligands and Natural Nucleic Acids. Journal of medicinal chemistry 65 (6) (2022)
Leyun Wu, Liping Zhou, Mengxia Mo, Tingting Liu, Chengkun Wu, Chunye Gong, Kai Lu, Likun Gong, Jianming Zhu, Zhijian Xu
SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2. Signal transduction and targeted therapy 7 (1) (2022)
Liping Zhou, Tingting Liu, Mengxia Mo, Yulong Shi, Leyun Wu, Yishui Li, Qiuping Qin, Jianming Zhu, Chengkun Wu, Likun Gong, Zhijian Xu
Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay. Journal of chemical information and modeling 62 (18) (2022)
Cheng Peng, Xinben Zhang, Zhijian Xu, Zhaoqiang Chen, Yanqing Yang, Tingting Cai, Jianming Zhu
D3PM: a comprehensive database for protein motions ranging from residue to domain. BMC bioinformatics 23 (1) (2022)
Haiguo Sun, Mengyu Xi, Qiang Jin, Zhengdan Zhu, Yani Zhang, Guihua Jia, Guanghao Zhu, Mengru Sun, Hongwei Zhang, Xuelian Ren, Yong Zhang, Zhijian Xu, He Huang, Jingshan Shen, Bo Li, Guangbo Ge, Kaixian Chen, Jianming Zhu
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium. Journal of medicinal chemistry 65 (17) (2022)
Yiru Long, Jianhua Sun, Tian-Zhang Song, Tingting Liu, Feng Tang, Xinxin Zhang, Longfei Ding, Yunqiu Miao, Jianming Zhu, Xiaoyan Pan, Qi An, Mian Qin, Xiankun Tong, Xionghua Peng, Pan Yu, Peng Zhu, Jianqing Xu, Xiaoyan Zhang, Yachun Zhang, Datao Liu, Ben Chen, Huilin Chen, Lei-Ke Zhang, Gengfu Xiao, Jianping Zuo, Wei Tang, Ji Zhou, Heng Li, Zhijian Xu, Hong-Yi Zheng, Xin-Yan Long, Qiuping Qin, Yong Gan, Jin Ren, Wei Huang, Yong-Tang Zheng, Guangyi Jin, Likun Gong
CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity. Cell discovery 8 (1) (2022)
Sanfeng Dong, Yitian Zhao, Yulong Shi, Zhijian Xu, Jingshan Shen, Qi Jia, Yiming Li, Kaixian Chen, Bo Li, Jianming Zhu
One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups. Organic & biomolecular chemistry 19 (7) (2021)
Xiaoyu Wang, Xinben Zhang, Cheng Peng, Yulong Shi, Hui-Yu Li, Zhijian Xu, Jianming Zhu
D3DistalMutation: a Database to Explore the Effect of Distal Mutations on Enzyme Activity. Journal of chemical information and modeling 61 (5) (2021)
Máté Erdélyi, Catharine Esterhuysen, Jianming Zhu
Halogen Bonding: From Fundamentals to Applications. ChemPlusChem 86 (9) (2021)
Jianzhong Chen, Wei Wang, Laixue Pang, Jianming Zhu
Unveiling conformational dynamics changes of H-Ras induced by mutations based on accelerated molecular dynamics. Physical chemistry chemical physics : PCCP 22 (37) (2021)
Yichen Huang, Fei Jin, Yosuke Funato, Zhijian Xu, Jianming Zhu, Jing Wang, Minxuan Sun, Yimeng Zhao, Ye Yu, Hiroaki Miki, Motoyuki Hattori
Structural basis for the Mg2+ recognition and regulation of the CorC Mg2+ transporter. Science advances 7 (7) (2021)
Qihua Zhang, Adam Smalley, Zhengdan Zhu, Zhijian Xu, Cheng Peng, Zhaoqiang Chen, Guangmin Yao, Jiye Shi, Jianming Zhu
Computational study of the substituent effect of halogenated fused-ring heteroaromatics on halogen bonding. Journal of molecular modeling 26 (10) (2020)
Cheng Peng, Jinan Wang, Yulong Shi, Zhijian Xu, Jianming Zhu
Increasing the Sampling Efficiency of Protein Conformational Change by Combining a Modified Replica Exchange Molecular Dynamics and Normal Mode Analysis. Journal of chemical theory and computation 17 (1) (2020)
Zhengdan Zhu, Zhijian Xu, Jianming Zhu
Interaction Nature and Computational Methods for Halogen Bonding: A Perspective. Journal of chemical information and modeling 60 (6) (2020)
Amina Abula, Zhijian Xu, Zhengdan Zhu, Cheng Peng, Zhaoqiang Chen, Jianming Zhu, Haji Akber Aisa
Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations. Journal of chemical information and modeling 60 (12) (2020)
Cheng Peng, Jinan Wang, Zhijian Xu, Tingting Cai, Jianming Zhu
Accurate prediction of relative binding affinities of a series of HIV-1 protease inhibitors using semi-empirical quantum mechanical charge. Journal of computational chemistry 41 (19) (2020)
Cheng Peng, Zhengdan Zhu, Yulong Shi, Xiaoyu Wang, Kaijie Mu, Yanqing Yang, Xinben Zhang, Zhijian Xu, Jianming Zhu
Computational Insights into the Conformational Accessibility and Binding Strength of SARS-CoV-2 Spike Protein to Human Angiotensin-Converting Enzyme 2. The journal of physical chemistry letters 11 (24) (2020)
Jianzhong Chen, Jinan Wang, Baohua Yin, Laixue Pang, Wei Wang, Jianming Zhu
Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions. ACS chemical neuroscience 10 (10) (2019)
Zhen Wang, Xiangrui Jiang, Xianglei Zhang, Guanghui Tian, Rulei Yang, Jianzhong Wu, Xiaoli Zou, Zheng Liu, Xiaojun Yang, Chunhui Wu, Jing Shi, Jianfeng Li, Jin Suo, Yu Wang, Rongxia Zhang, Zhijian Xu, Xudong Gong, Yang He, Jianming Zhu, Haji Akber Aisa, Hualiang Jiang, Yechun Xu, Jingshan Shen
Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. Journal of medicinal chemistry 62 (10) (2019)
Peng Liu, Xiangling Chen, Jianming Zhu, Bo Li, Zhaoqiang Chen, Guimin Wang, Haiguo Sun, Zhijian Xu, Zhixin Zhao, Chen Zhou, Chengying Xie, Liguang Lou, Weiliang Zhu
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response. ChemistryOpen 8 (3) (2019)
Zhijian Xu, Qian Zhang, Jiye Shi, Jianming Zhu
Underestimated Noncovalent Interactions in Protein Data Bank. Journal of chemical information and modeling 59 (8) (2019)
Pharit Kamsri, Chayanin Hanwarinroj, Naruedon Phusi, Thimpika Pornprom, Kampanart Chayajarus, Auradee Punkvang, Nitima Suttipanta, Potjanee Srimanote, Khomson Suttisintong, Chomphunuch Songsiriritthigul, Patchreenart Saparpakorn, Supa Hannongbua, Siriluk Rattanabunyong, Supaporn Seetaha, Kiattawee Choowongkomon, Sanya Sureram, Prasat Kittakoop, Poonpilas Hongmanee, Pitak Santanirand, Zhaoqiang Chen, Jianming Zhu, Rosemary A Blood, Yuiko Takebayashi, Philip Hinchliffe, Adrian J Mulholland, James Spencer, Pornpan Pungpo
Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography. Journal of chemical information and modeling 60 (1) (2019)
Zhaoqiang Chen, Xinben Zhang, Cheng Peng, Jinan Wang, Zhijian Xu, Kaixian Chen, Jiye Shi, Jianming Zhu
D3Pockets: A Method and Web Server for Systematic Analysis of Protein Pocket Dynamics. Journal of chemical information and modeling 59 (8) (2019)
Lei-Miao Yin, Yu-Dong Xu, Ling-Ling Peng, Ting-Ting Duan, Jia-Yuan Liu, Zhijian Xu, Wen-Qian Wang, Nan Guan, Xiao-Jie Han, Hai-Yan Li, Yu Pang, Yu Wang, Zhaoqiang Chen, Jianming Zhu, Linhong Deng, Ying-Li Wu, Guang-Bo Ge, Shuang Huang, Luis Ulloa, Yong-Qing Yang
Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance. Science translational medicine 10 (427) (2019)
Lixia Ding, Lu Wang, Kun Zou, Bo Li, Yunqing Song, Qihua Zhang, Yitian Zhao, Zhijian Xu, Guangbo Ge, Bo Zhao, Jianming Zhu
Discovery of dihydrooxazolo[2,3- a ]isoquinoliniums as highly specific inhibitors of hCE2. RSC advances 9 (61) (2019)
Ke-Wei Ding, Hongguang Xu, Yang Yang, Taoqi Li, Zhaoqiang Chen, Zhongxue Ge, Jianming Zhu, Wei-Jun Zheng
Mass Spectrometry and Theoretical Investigation of VN n+ ( n = 8, 9, and 10) Clusters. The journal of physical chemistry. A 122 (20) (2018)
Haiyan Cai, Ting Wang, Zhuo Yang, Zhijian Xu, Guimin Wang, He-Yao Wang, Jianming Zhu, Kaixian Chen
Combined Virtual Screening and Substructure Search for Discovery of Novel FABP4 Inhibitors. Journal of chemical information and modeling 57 (9) (2017)
Qiang Shao, Jianming Zhu
How Well Can Implicit Solvent Simulations Explore Folding Pathways? A Quantitative Analysis of α-Helix Bundle Proteins. Journal of chemical theory and computation 13 (12) (2017)
Yunxiang Wu, Zhaoqiang Chen, Yaxi Yang, Jianming Zhu, Bing Zhou
Rh(III)-Catalyzed Redox-Neutral Unsymmetrical C-H Alkylation and Amidation Reactions of N-Phenoxyacetamides. Journal of the American Chemical Society 140 (1) (2017)
Gaomei Chang, Wenqin Xiao, Zhijian Xu, Dandan Yu, Bo Li, Yong Zhang, Xi Sun, Yongsheng Xie, Shuaikang Chang, Lu Gao, Gege Chen, Liangning Hu, Bingqian Xie, Bojie Dai, Jianming Zhu, Jumei Shi
Pterostilbene Induces Cell Apoptosis and Cell Cycle Arrest in T-Cell Leukemia/Lymphoma by Suppressing the ERK1/2 Pathway. BioMed research international 2017 (2017)

Jianming Zhu.css-eqlu8i{font-size:small;padding-left:4px;} (Weiliang Zhu)

Publication Activity (10 Years)

Top Topics

Top Venues

Jianming Zhu (Weiliang Zhu)