Jingshan Shen

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 32

Top Topics

Drug Administration

Polycyclic Aromatic Hydrocarbons

Structural Basis

Respiratory Syncytial Virus

Top Venues

Signal transduction and targeted therapy

The Journal of organic chemistry

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Abdullajon Odilov, Xudong Gong, Hongjian Qin, Emmanuel Mintah Bonku, Fuqiang Zhu, Feipu Yang, Jingshan Shen
An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization. The Journal of organic chemistry 89 (10) (2024)
Abdullajon Odilov, Xudong Gong, Hongjian Qin, Emmanuel Mintah Bonku, Fuqiang Zhu, Feipu Yang, Jingshan Shen
An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization. The Journal of organic chemistry (2024)
Hongjian Qin, Zijian Han, Emmanuel Mintah Bonku, Haiguo Sun, Abdullajon Odilov, Fuqiang Zhu, Safomuddin Abduahadi, Jianming Zhu, Jingshan Shen, Haji Akber Aisa
Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds. Communications chemistry 7 (1) (2024)
Emmanuel Mintah Bonku, Hongjian Qin, Abdullajon Odilov, Safomuddin Abduahadi, Samuel Desta Guma, Feipu Yang, Fuqiang Zhu, Haji Akber Aisa, Jingshan Shen
Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from o -bromoarylamine and nitriles. RSC advances 14 (10) (2024)
Emmanuel Mintah Bonku, Hongjian Qin, Abdullajon Odilov, Safomuddin Abduahadi, Samuel Desta Guma, Feipu Yang, Fuqiang Zhu, Haji Akber Aisa, Jingshan Shen
Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from o -bromoarylamine and nitriles. RSC advances 14 (10) (2024)
Hongjian Qin, Zijian Han, Emmanuel Mintah Bonku, Haiguo Sun, Abdullajon Odilov, Fuqiang Zhu, Safomuddin Abduahadi, Jianming Zhu, Jingshan Shen, Haji Akber Aisa
Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds. Communications chemistry 7 (1) (2024)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Li Xiang, Tianwen Hu, Haitao Xue, Wenfang Pan, Yuanchao Xie, Jingshan Shen
Synthesis and evaluation of NHC derivatives and 4'-fluorouridine prodrugs. Organic & biomolecular chemistry (2023)
Xiangrui Jiang, Haixia Su, Weijuan Shang, Feng Zhou, Yan Zhang, Wenfeng Zhao, Qiumeng Zhang, Hang Xie, Lei Jiang, Tianqing Nie, Feipu Yang, Muya Xiong, Xiaoxing Huang, Minjun Li, Ping Chen, Shaoping Peng, Geng-Fu Xiao, Hualiang Jiang, Renhong Tang, Lei-Ke Zhang, Jingshan Shen, Yechun Xu
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir. Nature communications 14 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Yumin Zhang, Yuan Sun, Yuanchao Xie, Weijuan Shang, Zhen Wang, Hualiang Jiang, Jingshan Shen, Geng-Fu Xiao, Lei-Ke Zhang
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir. Signal transduction and targeted therapy 8 (1) (2023)
Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling, Xiangrui Jiang, Xiangyun Lu, Chuan Li, Likun Gong, Guangbo Ge, Yani Zhang, Yi Zang, Tian-Zhang Song, Xiao-Li Feng, Ren-Rong Tian, Jia Ji, Miaojin Zhu, Nanping Wu, Chunhui Wu, Zhen Wang, Yechun Xu, Cheng Peng, Min Zheng, Junling Yang, Feifei Du, Junliang Wu, Peipei Wang, Jingshan Shen, Jianliang Zhang, Yong-Tang Zheng, Hang-Ping Yao, Jianming Zhu
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy 8 (1) (2023)
Hongjian Qin, Abdullajon Odilov, Emmanuel Mintah Bonku, Fuqiang Zhu, Tianwen Hu, He Liu, Haji Akber Aisa, Jingshan Shen
Facile Synthesis of Benzimidazoles via N -Arylamidoxime Cyclization. ACS omega 7 (49) (2022)
Hongjian Qin, Abdullajon Odilov, Emmanuel Mintah Bonku, Fuqiang Zhu, Tianwen Hu, He Liu, Haji Akber Aisa, Jingshan Shen
Facile Synthesis of Benzimidazoles via N -Arylamidoxime Cyclization. ACS omega 7 (49) (2022)
Ruxue Zhang, Yumin Zhang, Wei Zheng, Weijuan Shang, Yan Wu, Ning Li, Jun Xiong, Hualiang Jiang, Jingshan Shen, Gengfu Xiao, Yuanchao Xie, Lei-Ke Zhang
Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model. Signal transduction and targeted therapy 7 (1) (2022)
Haiguo Sun, Mengyu Xi, Qiang Jin, Zhengdan Zhu, Yani Zhang, Guihua Jia, Guanghao Zhu, Mengru Sun, Hongwei Zhang, Xuelian Ren, Yong Zhang, Zhijian Xu, He Huang, Jingshan Shen, Bo Li, Guangbo Ge, Kaixian Chen, Jianming Zhu
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium. Journal of medicinal chemistry 65 (17) (2022)
Sanfeng Dong, Yitian Zhao, Yulong Shi, Zhijian Xu, Jingshan Shen, Qi Jia, Yiming Li, Kaixian Chen, Bo Li, Jianming Zhu
One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups. Organic & biomolecular chemistry 19 (7) (2021)
Yuanchao Xie, Wanchao Yin, Yumin Zhang, Weijuan Shang, Zhen Wang, Xiaodong Luan, Guanghui Tian, Haji A Aisa, Yechun Xu, Gengfu Xiao, Jia Li, Hualiang Jiang, Shu-Yang Zhang, Lei-Ke Zhang, H Eric Xu, Jingshan Shen
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2. Cell research 31 (11) (2021)
Yuanchao Xie, Xiaozhen Guo, Tianwen Hu, Daibao Wei, Xiuli Ma, Jiaqiang Wu, Bing Huang, Jingshan Shen
Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and β-D-N4-hydroxycytidine. Virologica Sinica 36 (5) (2021)
Hongjie Qian, Qian Chen, Liyu Liang, Yang Zou, Huahua Pu, Liang Xin, Rong Song, Tingting Li, Huijuan Zhu, Yu Wang, Guanghui Tian, Jingshan Shen, Hualiang Jiang, Chen Yu, Zhen Wang, Jingying Jia
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects. Drug design, development and therapy 15 (2021)
Bingqing Xia, Xurui Shen, Yang He, Xiaoyan Pan, Feng-Liang Liu, Yi Wang, Feipu Yang, Sui Fang, Yan Wu, Zilei Duan, Xiaoli Zuo, Zhuqing Xie, Xiangrui Jiang, Ling Xu, Hao Chi, Shuangqu Li, Qian Meng, Hu Zhou, Yubo Zhou, Xi Cheng, Xiaoming Xin, Lin Jin, Hai-Lin Zhang, Dan-Dan Yu, Ming-Hua Li, Xiao-Li Feng, Jie-Kai Chen, Hualiang Jiang, Gengfu Xiao, Yong-Tang Zheng, Lei-Ke Zhang, Jingshan Shen, Jia Li, Zhaobing Gao
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target. Cell research 31 (8) (2021)
Haitao Xue, Shuang Guo, Tianwen Hu, Daibao Wei, Yuanchao Xie, Jingshan Shen
Synthesis and antiviral activity of 2'-deoxy-6'-substituted carbocyclic nucleosides. Chemical biology & drug design (2021)
Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Changqiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Lei-Ke Zhang, Yang Ye, Yechun Xu
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease. Nature communications 12 (1) (2021)
Yuanchao Xie, Tianwen Hu, Yan Zhang, Daibao Wei, Wei Zheng, Fuqiang Zhu, Guanghui Tian, Haji Akber Aisa, Jingshan Shen
Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate. The Journal of organic chemistry 86 (7) (2021)
Xudong Gong, Changliang Sun, Melkamu Alemu Abame, Wenqiang Shi, Yuanchao Xie, Wanbin Xu, Fuqiang Zhu, Yan Zhang, Jingshan Shen, Haji Akber Aisa
Synthesis of CBD and Its Derivatives Bearing Various C4'-Side Chains with a Late-Stage Diversification Method. The Journal of organic chemistry 85 (4) (2020)
Wei Zheng, Zhen Wang, Xiangrui Jiang, Qingjie Zhao, Jingshan Shen
Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives. Journal of medicinal chemistry 63 (24) (2020)
Wanchao Yin, Chunyou Mao, Xiaodong Luan, Dan-Dan Shen, Qingya Shen, Haixia Su, Xiaoxi Wang, Fulai Zhou, Wenfeng Zhao, Minqi Gao, Shenghai Chang, Yuan-Chao Xie, Guanghui Tian, He-Wei Jiang, Sheng-Ce Tao, Jingshan Shen, Yi Jiang, Hualiang Jiang, Yechun Xu, Shu-Yang Zhang, Yan Zhang, H Eric Xu
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science (New York, N.Y.) 368 (6498) (2020)
Junchi Zhang, Rui Li, Fuqiang Zhu, Changliang Sun, Jingshan Shen
An improved synthesis of telmisartan via the copper-catalyzed cyclization of o -haloarylamidines. RSC advances 10 (23) (2020)
Zhen Wang, Xiangrui Jiang, Xianglei Zhang, Guanghui Tian, Rulei Yang, Jianzhong Wu, Xiaoli Zou, Zheng Liu, Xiaojun Yang, Chunhui Wu, Jing Shi, Jianfeng Li, Jin Suo, Yu Wang, Rongxia Zhang, Zhijian Xu, Xudong Gong, Yang He, Jianming Zhu, Haji Akber Aisa, Hualiang Jiang, Yechun Xu, Jingshan Shen
Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. Journal of medicinal chemistry 62 (10) (2019)
Weiming Chen, Changliang Sun, Yan Zhang, Tianwen Hu, Fuqiang Zhu, Xiangrui Jiang, Melkamu Alemu Abame, Feipu Yang, Jin Suo, Jing Shi, Jingshan Shen, Haji Akber Aisa
Oxidative Aromatization of 3,4-Dihydroquinolin-2(1 H)-ones to Quinolin-2(1 H)-ones Using Transition-Metal-Activated Persulfate Salts. The Journal of organic chemistry 84 (13) (2019)