Hugo J Bellen (Hugo Bellen)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 73

Top Venues

eLife

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Nature neuroscience

HHMI and BCM

UCDavis (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

HHMI and BCM Sep 01 1989

United States

Professor :: MHG

Education History

UCDavis

United States

PHD :: Genetics

Publications

Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Jenny Zhe Liao, Hyung-Lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C Marcogliese, Katherine Sew, Hugo J Bellen, Esther M Verheyen
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature communications 15 (1) (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Lindsey D Goodman, Matthew J Moulton, Hugo J Bellen
Glial lipid droplets resolve ROS during sleep. Nature neuroscience (2024)
Lindsey D Goodman, Matthew J Moulton, Hugo J Bellen
Glial lipid droplets resolve ROS during sleep. Nature neuroscience 27 (4) (2024)
Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran, Jubao Duan
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia. Research square (2024)
Debdeep Dutta, Oguz Kanca, Rishi V Shridharan, Paul C Marcogliese, Benjamin Steger, Marie Morimoto, F Graeme Frost, Ellen Macnamara, null null, Michael F Wangler, Shinya Yamamoto, Andreas Jenny, David Adams, May C Malicdan, Hugo J Bellen
Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Debdeep Dutta, Oguz Kanca, Rishi V Shridharan, Paul C Marcogliese, Benjamin Steger, Marie Morimoto, F Graeme Frost, Ellen Macnamara, null null, Michael F Wangler, Shinya Yamamoto, Andreas Jenny, David Adams, May C Malicdan, Hugo J Bellen
Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Jenny Zhe Liao, Hyung-Lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C Marcogliese, Katherine Sew, Hugo J Bellen, Esther M Verheyen
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature communications 15 (1) (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran, Jubao Duan
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia. Research square (2024)
Jubao Duan, Alena Kozlova, Siwei Zhang, Ari Sudwards, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia. Research square (2024)
Dongxue Mao, Chaozhong Liu, Linhua Wang, Rami Ai-Ouran, Cole Deisseroth, Sasidhar Pasupuleti, Seon Young Kim, Lucian Li, Jill Anne Rosenfeld, Linyan Meng, Lindsay C Burrage, Michael F Wangler, Shinya Yamamoto, null null, Michael Santana, Victor Perez, Priyank Shukla, Christine M Eng, Brendan H Lee, Bo Yuan, Fan Xia, Hugo J Bellen, Pengfei Liu, Zhandong Liu
AI-MARRVEL - A Knowledge-Driven AI System for Diagnosing Mendelian Disorders. NEJM AI 1 (5) (2024)
Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran, Jiaye Chen, Chung-Yi Liang, Erin Harrison, Christina Ko, Ao-Lin Hsu, Shinya Yamamoto, Yanyan Qi, Hugo J Bellen, Hongjie Li
Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models. bioRxiv : the preprint server for biology (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran, Jiaye Chen, Chung-Yi Liang, Erin Harrison, Christina Ko, Ao-Lin Hsu, Shinya Yamamoto, Yanyan Qi, Hugo J Bellen, Hongjie Li
Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models. bioRxiv : the preprint server for biology (2024)
Dongxue Mao, Chaozhong Liu, Linhua Wang, Rami Ai-Ouran, Cole Deisseroth, Sasidhar Pasupuleti, Seon Young Kim, Lucian Li, Jill Anne Rosenfeld, Linyan Meng, Lindsay C Burrage, Michael F Wangler, Shinya Yamamoto, null null, Michael Santana, Victor Perez, Priyank Shukla, Christine M Eng, Brendan H Lee, Bo Yuan, Fan Xia, Hugo J Bellen, Pengfei Liu, Zhandong Liu
AI-MARRVEL - A Knowledge-Driven AI System for Diagnosing Mendelian Disorders. NEJM AI 1 (5) (2024)
Debdeep Dutta, Oguz Kanca, Rishi V Shridharan, Paul C Marcogliese, Benjamin Steger, Marie Morimoto, F Graeme Frost, Ellen Macnamara, null null, Michael F Wangler, Shinya Yamamoto, Andreas Jenny, David Adams, May C Malicdan, Hugo J Bellen
Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Jenny Zhe Liao, Hyung-Lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C Marcogliese, Katherine Sew, Hugo J Bellen, Esther M Verheyen
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature communications 15 (1) (2024)
Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran, Jiaye Chen, Chung-Yi Liang, Erin Harrison, Christina Ko, Ao-Lin Hsu, Shinya Yamamoto, Yanyan Qi, Hugo J Bellen, Hongjie Li
Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models. bioRxiv : the preprint server for biology (2024)
Jenny Zhe Liao, Hyung-Lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C Marcogliese, Katherine Sew, Hugo J Bellen, Esther M Verheyen
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature communications 15 (1) (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Debdeep Dutta, Oguz Kanca, Rishi V Shridharan, Paul C Marcogliese, Benjamin Steger, Marie Morimoto, F Graeme Frost, Ellen Macnamara, null null, Michael F Wangler, Shinya Yamamoto, Andreas Jenny, David Adams, May C Malicdan, Hugo J Bellen
Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Jenny Zhe Liao, Hyung-Lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C Marcogliese, Katherine Sew, Hugo J Bellen, Esther M Verheyen
Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature communications 15 (1) (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Dongxue Mao, Chaozhong Liu, Linhua Wang, Rami Ai-Ouran, Cole Deisseroth, Sasidhar Pasupuleti, Seon Young Kim, Lucian Li, Jill Anne Rosenfeld, Linyan Meng, Lindsay C Burrage, Michael F Wangler, Shinya Yamamoto, null null, Michael Santana, Victor Perez, Priyank Shukla, Christine M Eng, Brendan H Lee, Bo Yuan, Fan Xia, Hugo J Bellen, Pengfei Liu, Zhandong Liu
AI-MARRVEL - A Knowledge-Driven AI System for Diagnosing Mendelian Disorders. NEJM AI 1 (5) (2024)
Lindsey D Goodman, Matthew J Moulton, Hugo J Bellen
Glial lipid droplets resolve ROS during sleep. Nature neuroscience 27 (4) (2024)
Lindsey D Goodman, Isha Ralhan, Xin Li, Shen-Zhao Lu, Matthew J Moulton, Ye-Jin Park, Pinghan Zhao, Oguz Kanca, Ziyaneh S Ghaderpour Taleghani, Rose E Goodchild, Joshua M Shulman, Kanae Ando, Kai Sun, Maria S Ioannou, Hugo J Bellen
Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nature neuroscience (2024)
Debdeep Dutta, Oguz Kanca, Rishi V Shridharan, Paul C Marcogliese, Benjamin Steger, Marie Morimoto, F Graeme Frost, Ellen Macnamara, null null, Michael F Wangler, Shinya Yamamoto, Andreas Jenny, David Adams, May C Malicdan, Hugo J Bellen
Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/ PARK14 ). eLife 12 (2023)
Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14). eLife 12 (2023)
Chih-Yen Wang, Zhongyuan Zuo, Juyeon Jo, Kyoung In Kim, Christine Madamba, Qi Ye, Sung Yun Jung, Hugo J Bellen, Hyun Kyoung Lee
Daam2 phosphorylation by CK2α negatively regulates Wnt activity during white matter development and injury. Proceedings of the National Academy of Sciences of the United States of America 120 (35) (2023)
Debdeep Dutta, Oguz Kanca, Seul Kee Byeon, Paul C Marcogliese, Zhongyuan Zuo, Rishi V Shridharan, Jun Hyoung Park, null null, Guang Lin, Ming Ge, Gali Heimer, Jennefer N Carter, Matthew T Wheeler, Benny Abraham Kaipparettu, Akhilesh Pandey, Hugo J Bellen
A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels. Nature metabolism (2023)
Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14). eLife 12 (2023)
Xueyang Pan, Albert N Alvarez, Mengqi Ma, Shen-Zhao Lu, Michael W Crawford, Lauren C Briere, Oguz Kanca, Shinya Yamamoto, David A Sweetser, Jenny L Wilson, Ruth J Napier, Jonathan N Pruneda, Hugo J Bellen
Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays. medRxiv : the preprint server for health sciences (2023)
Shinya Yamamoto, Oguz Kanca, Michael F Wangler, Hugo J Bellen
Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans. Nature reviews. Genetics (2023)
Tzu-Chiao Lu, Maria Brbic, Ye-Jin Park, Tyler Jackson, Jiaye Chen, Sai Saroja Kolluru, Yanyan Qi, Nadja Sandra Katheder, Xiaoyu Tracy Cai, Seungjae Lee, Yen-Chung Chen, Niccole Auld, Chung-Yi Liang, Sophia H Ding, Doug Welsch, Samuel D'Souza, Angela Oliveira Pisco, Robert C Jones, Jure Leskovec, Eric C Lai, Hugo J Bellen, Liqun Luo, Heinrich Jasper, Stephen R Quake, Hongjie Li
Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution. Science (New York, N.Y.) 380 (6650) (2023)
Isha Ralhan, Jinlan Chang, Matthew J Moulton, Lindsey D Goodman, Nathanael Y J Lee, Greg Plummer, Hilda Amalia Pasolli, Doreen Matthies, Hugo J Bellen, Maria S Ioannou
Autolysosomal exocytosis of lipids protect neurons from ferroptosis. The Journal of cell biology 222 (6) (2023)
Hilary Scott, Boris Novikov, Berrak Ugur, Brooke Allen, Ilya Mertsalov, Pedro Monagas-Valentin, Melissa Koff, Sarah Baas Robinson, Kazuhiro Aoki, Raisa Veizaj, Dirk Lefeber, Michael Tiemeyer, Hugo J Bellen, Vladislav M Panin
Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila . eLife 12 (2023)
Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/ PARK14 ). eLife 12 (2023)
Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14). eLife 12 (2023)
Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14). eLife 12 (2023)
Xueyang Pan, Albert N Alvarez, Mengqi Ma, Shen-Zhao Lu, Michael W Crawford, Lauren C Briere, Oguz Kanca, Shinya Yamamoto, David A Sweetser, Jenny L Wilson, Ruth J Napier, Jonathan N Pruneda, Hugo J Bellen
Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays. eLife 12 (2023)
Yupu Wang, Meike Lobb-Rabe, James Ashley, Purujit Chatterjee, Veera Anand, Hugo J Bellen, Oguz Kanca, Robert A Carrillo
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Development (Cambridge, England) 149 (10) (2022)
Paul C Marcogliese, Debdeep Dutta, Shrestha Sinha Ray, Nghi D P Dang, Zhongyuan Zuo, Yuchun Wang, Di Lu, Fatima Fazal, Thomas A Ravenscroft, Hyunglok Chung, Oguz Kanca, JiJun Wan, Emilie D Douine, Undiagnosed Diseases Network, Loren D M Pena, Shinya Yamamoto, Stanley F Nelson, Matthew Might, Kathrin C Meyer, Nan Cher Yeo, Hugo J Bellen
Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Science advances 8 (3) (2022)
Matthew J Moulton, Scott Barish, Isha Ralhan, Jinlan Chang, Lindsey D Goodman, Jake G Harland, Paul C Marcogliese, Jan O Johansson, Maria S Ioannou, Hugo J Bellen
Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes. Proceedings of the National Academy of Sciences of the United States of America 118 (52) (2022)
Felipe Martelli, Natalia H Hernandes, Zhongyuan Zuo, Julia Wang, Ching-On Wong, Nicholas E Karagas, Ute Roessner, Thusita Rupasinghe, Charles Robin, Kartik Venkatachalam, Trent Perry, Philip Batterham, Hugo J Bellen
Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies. eLife 11 (2022)
Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon
Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila . eLife 11 (2022)
Liping Wang, Guang Lin, Zhongyuan Zuo, Yarong Li, Seul Kee Byeon, Akhilesh Pandey, Hugo J Bellen
Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia. Science advances 8 (28) (2022)
Keith C Cheng, Rebecca D Burdine, Mary E Dickinson, Stephen C Ekker, Alex Y Lin, K C Kent Lloyd, Cathleen M Lutz, Calum A MacRae, John H Morrison, David H O'Connor, John H Postlethwait, Crystal D Rogers, Susan Sanchez, Julie H Simpson, William S Talbot, Douglas C Wallace, Jill M Weimer, Hugo J Bellen
Promoting validation and cross-phylogenetic integration in model organism research. Disease models & mechanisms 15 (9) (2022)
J Michael Harnish, Lucian Li, Sanja Rogic, Guillaume Poirier-Morency, Seon-Young Kim, null null, Kym M Boycott, Michael F Wangler, Hugo J Bellen, Philip Hieter, Paul Pavlidis, Zhandong Liu, Shinya Yamamoto
ModelMatcher: A scientist-centric online platform to facilitate collaborations between stakeholders of rare and undiagnosed disease research. Human mutation 43 (6) (2022)
Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen
An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. eLife 11 (2022)
Hugo J Bellen
Lord of the fruit flies: an interview with Hugo Bellen. Disease models & mechanisms 15 (3) (2022)
Hugo J Bellen, E J A Hubbard, Ruth Lehmann, Hiten D Madhani, Lila Solnica-Krezel, E Michelle Southard-Smith
Model organism databases are in jeopardy. Development (Cambridge, England) 148 (19) (2021)
Kathleen M Cunningham, Kirstin Maulding, Kai Ruan, Mumine Senturk, Jonathan C Grima, Hyun Sung, Zhongyuan Zuo, Helen Song, Junli Gao, Sandeep Dubey, Jeffrey D Rothstein, Ke Zhang, Hugo J Bellen, Thomas E Lloyd
TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. eLife 9 (2020)
Thomas A Ravenscroft, Jasper Janssens, Pei-Tseng Lee, Burak Tepe, Paul C Marcogliese, Samira Makhzami, Todd C Holmes, Stein Aerts, Hugo J Bellen
Drosophila Voltage-Gated Sodium Channels Are Only Expressed in Active Neurons and Are Localized to Distal Axonal Initial Segment-like Domains. The Journal of neuroscience : the official journal of the Society for Neuroscience 40 (42) (2020)
Felipe Martelli, Zuo Zhongyuan, Julia Wang, Ching-On Wong, Nicholas E Karagas, Ute Roessner, Thusitha Rupasinghe, Kartik Venkatachalam, Trent Perry, Hugo J Bellen, Philip Batterham
Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 117 (41) (2020)
Nichole L Link, Hugo J Bellen
Using Drosophila to drive the diagnosis and understand the mechanisms of rare human diseases. Development (Cambridge, England) 147 (21) (2020)
Hui Ye, Shamsideen A Ojelade, David Li-Kroeger, Zhongyuan Zuo, Liping Wang, Yarong Li, Jessica Yj Gu, Ulrich Tepass, Avital Adah Rodal, Hugo J Bellen, Joshua M Shulman
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. eLife 9 (2020)
Mumine Senturk, Dongxue Mao, Hugo J Bellen
Loss of proteins associated with amyotrophic lateral sclerosis affects lysosomal acidification via different routes. Autophagy 15 (8) (2019)
Oguz Kanca, Jonathan Zirin, Jorge Garcia-Marques, Shannon Marie Knight, Donghui Yang-Zhou, Gabriel Amador, Hyunglok Chung, Zhongyuan Zuo, Liwen Ma, Yuchun He, Wen-Wen Lin, Ying Fang, Ming Ge, Shinya Yamamoto, Karen L Schulze, Yanhui Hu, Allan C Spradling, Stephanie E Mohr, Norbert Perrimon, Hugo J Bellen
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. eLife 8 (2019)
Dongxue Mao, Guang Lin, Burak Tepe, Zhongyuan Zuo, Kai Li Tan, Mumine Senturk, Sheng Zhang, Benjamin R Arenkiel, Marco Sardiello, Hugo J Bellen
VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway. Autophagy 15 (7) (2019)
Hui Guo, Elisa Bettella, Paul C Marcogliese, Rongjuan Zhao, Jonathan C Andrews, Tomasz Jan Nowakowski, Madelyn A Gillentine, Kendra Hoekzema, Tianyun Wang, Huidan Wu, Sharayu Jangam, Cenying Liu, Hailun Ni, Marjolein H Willemsen, Bregje W van Bon, Tuula Rinne, Servi J C Stevens, Tjitske Kleefstra, Han G Brunner, Helger G Yntema, Min Long, Wenjing Zhao, Zhengmao Hu, Cindy Colson, Nicolas Richard, Charles E Schwartz, Corrado Romano, Lucia Castiglia, Maria Bottitta, Shweta U Dhar, Deanna J Erwin, Lisa Emrick, Boris Keren, Alexandra Afenjar, Baosheng Zhu, Bing Bai, Pawel Stankiewicz, Kristin Herman, null null, Saadet Mercimek-Mahmutoglu, Jane Juusola, Amy B Wilfert, Rami Abou Jamra, Benjamin Büttner, Heather C Mefford, Alison M Muir, Ingrid E Scheffer, Brigid M Regan, Stephen Malone, Jozef Gecz, Jan Cobben, Janneke M Weiss, Quinten Waisfisz, Emilia K Bijlsma, Mariëtte J V Hoffer, Claudia A L Ruivenkamp, Stefano Sartori, Fan Xia, Jill A Rosenfeld, Raphael A Bernier, Michael F Wangler, Shinya Yamamoto, Kun Xia, Alexander P A Stegmann, Hugo J Bellen, Alessandra Murgia, Evan E Eichler
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. Nature communications 10 (1) (2019)
Mümine Şentürk, Guang Lin, Zhongyuan Zuo, Dongxue Mao, Emma Watson, Antonios G Mikos, Hugo J Bellen
Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nature cell biology 21 (3) (2019)
Oguz Kanca, Hugo J Bellen, Frank Schnorrer
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. Genetics 207 (2) (2018)
David Li-Kroeger, Oguz Kanca, Pei-Tseng Lee, Sierra Cowan, Michael T Lee, Manish Jaiswal, Jose Luis Salazar, Yuchun He, Zhongyuan Zuo, Hugo J Bellen
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. eLife 7 (2018)
Pei-Tseng Lee, Guang Lin, Wen-Wen Lin, Fengqiu Diao, Benjamin H White, Hugo J Bellen
A kinase-dependent feedforward loop affects CREBB stability and long term memory formation. eLife 7 (2018)
Pei-Tseng Lee, Jonathan Zirin, Oguz Kanca, Wen-Wen Lin, Karen L Schulze, David Li-Kroeger, Rong Tao, Colby Devereaux, Yanhui Hu, Verena Chung, Ying Fang, Yuchun He, Hongling Pan, Ming Ge, Zhongyuan Zuo, Benjamin E Housden, Stephanie E Mohr, Shinya Yamamoto, Robert W Levis, Allan C Spradling, Norbert Perrimon, Hugo J Bellen
A gene-specific T2A-GAL4 library for Drosophila. eLife 7 (2018)
Sonal Nagarkar Jaiswal, Sathiyanarayanan Manivannan, Zhongyuan Zuo, Hugo J Bellen
A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells. eLife 6 (2017)
Michael F Wangler, Shinya Yamamoto, Hsiao-Tuan Chao, Jennifer E Posey, Monte Westerfield, John H Postlethwait, null null, Philip Hieter, Kym M Boycott, Philippe M Campeau, Hugo J Bellen
Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research. Genetics 207 (1) (2017)
Kuchuan Chen, Guang Lin, Nele A Haelterman, Tammy Szu-Yu Ho, Tongchao Li, Zhihong Li, Lita Duraine, Brett H Graham, Manish Jaiswal, Shinya Yamamoto, Matthew N Rasband, Hugo J Bellen
Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. eLife 5 (2016)
Kuchuan Chen, Tammy Szu-Yu Ho, Guang Lin, Kai Li Tan, Matthew N Rasband, Hugo J Bellen
Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals. eLife 5 (2016)
Tongchao Li, Nikolaos Giagtzoglou, Daniel F Eberl, Sonal Nagarkar Jaiswal, Tiantian Cai, Dorothea Godt, Andrew K Groves, Hugo J Bellen
The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. eLife 5 (2016)
Michael F Wangler, Shinya Yamamoto, Hugo J Bellen
Fruit flies in biomedical research. Genetics 199 (3) (2015)

Hugo J Bellen.css-eqlu8i{font-size:small;padding-left:4px;} (Hugo Bellen)

Publication Activity (10 Years)

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Hugo J Bellen (Hugo Bellen)