Yan Jessie Zhang (Y Jessie Zhang, Yan Zhang)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Topics

Mass Spectrometry

Structural Basis

Top Venues

Nature communications

Journal of the American Society for Mass Spectrometry

This page only lists publications with an associated author ORCID identifier.

Publications

Kevin B Reed, Wantae Kim, Hongyuan Lu, Clayton T Larue, Shirley Guo, Sierra M Brooks, Michael R Montez, James W Wagner, Yan Jessie Zhang, Hal S Alper
Evolving dual-trait EPSP synthase variants using a synthetic yeast selection system. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Kevin B Reed, Wantae Kim, Hongyuan Lu, Clayton T Larue, Shirley Guo, Sierra M Brooks, Michael R Montez, James W Wagner, Yan Jessie Zhang, Hal S Alper
Evolving dual-trait EPSP synthase variants using a synthetic yeast selection system. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Simon D'Oelsnitz, Daniel J Diaz, Wantae Kim, Daniel J Acosta, Tyler L Dangerfield, Mason W Schechter, Matthew B Minus, James R Howard, Hannah Do, James M Loy, Hal S Alper, Yan Jessie Zhang, Andrew D Ellington
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme. Nature communications 15 (1) (2024)
Edwin E Escobar, Wanjie Yang, Michael B Lanzillotti, Kyle J Juetten, Samuel Shields, Dionicio Siegel, Yan Jessie Zhang, Jennifer S Brodbelt
Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Edwin E Escobar, Wanjie Yang, Michael B Lanzillotti, Kyle J Juetten, Samuel Shields, Dionicio Siegel, Yan Jessie Zhang, Jennifer S Brodbelt
Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Svetlana B Panina, Joshua V Schweer, Qian Zhang, Gaurav Raina, Haley A Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Yan Jessie Zhang
Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells. BMC biology 22 (1) (2024)
Svetlana B Panina, Joshua V Schweer, Qian Zhang, Gaurav Raina, Haley A Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Yan Jessie Zhang
Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells. BMC biology 22 (1) (2024)
Simon D'Oelsnitz, Daniel J Diaz, Wantae Kim, Daniel J Acosta, Tyler L Dangerfield, Mason W Schechter, Matthew B Minus, James R Howard, Hannah Do, James M Loy, Hal S Alper, Yan Jessie Zhang, Andrew D Ellington
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme. Nature communications 15 (1) (2024)
Svetlana B Panina, Joshua V Schweer, Qian Zhang, Gaurav Raina, Haley A Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Yan Jessie Zhang
Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells. BMC biology 22 (1) (2024)
Svetlana B Panina, Joshua V Schweer, Qian Zhang, Gaurav Raina, Haley A Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Yan Jessie Zhang
Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells. BMC biology 22 (1) (2024)
Kevin B Reed, Wantae Kim, Hongyuan Lu, Clayton T Larue, Shirley Guo, Sierra M Brooks, Michael R Montez, James W Wagner, Yan Jessie Zhang, Hal S Alper
Evolving dual-trait EPSP synthase variants using a synthetic yeast selection system. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Edwin E Escobar, Wanjie Yang, Michael B Lanzillotti, Kyle J Juetten, Samuel Shields, Dionicio Siegel, Yan Jessie Zhang, Jennifer S Brodbelt
Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society for Mass Spectrometry (2024)
Simon D'Oelsnitz, Daniel J Diaz, Wantae Kim, Daniel J Acosta, Tyler L Dangerfield, Mason W Schechter, Matthew B Minus, James R Howard, Hannah Do, James M Loy, Hal S Alper, Yan Jessie Zhang, Andrew D Ellington
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme. Nature communications 15 (1) (2024)
Svetlana B Panina, Joshua V Schweer, Qian Zhang, Gaurav Raina, Haley A Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Yan Jessie Zhang
Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells. BMC biology 22 (1) (2024)
Edwin E Escobar, Wanjie Yang, Michael B Lanzillotti, Kyle J Juetten, Samuel Shields, Dionicio Siegel, Yan Jessie Zhang, Jennifer S Brodbelt
Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society for Mass Spectrometry 35 (6) (2024)
Qian Zhang, Wantae Kim, Svetlana B Panina, Joshua E Mayfield, Bede Portz, Yan Jessie Zhang
Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription. Nature communications 15 (1) (2024)
Simon D'Oelsnitz, Daniel J Diaz, Wantae Kim, Daniel J Acosta, Tyler L Dangerfield, Mason W Schechter, Matthew B Minus, James R Howard, Hannah Do, James M Loy, Hal S Alper, Yan Jessie Zhang, Andrew D Ellington
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme. Nature communications 15 (1) (2024)
Yi-Wei Liu, Nicholas M Marshall, Sheng-Song Yu, Wantae Kim, Yi-Gui Gao, Howard Robinson, Mark J Nilges, Yan Jessie Zhang, Siu Yee New, Yi Lu
Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin. Inorganic chemistry (2023)
Kaci Erwin, R Yvette Moreno, Bert-Jan Baas, Yan Jessie Zhang, Christian P Whitman
Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases. Biochemistry (2023)
Simon D'Oelsnitz, Wantae Kim, Nathaniel T Burkholder, Kamyab Javanmardi, Ross Thyer, Yan Jessie Zhang, Hal S Alper, Andrew D Ellington
Using fungible biosensors to evolve improved alkaloid biosyntheses. Nature chemical biology 18 (9) (2022)
Wantae Kim, Tzu-Yu Chen, Lide Cha, Grace Zhou, Kristi Xing, Nicholas Koenig Canty, Yan Jessie Zhang, Wei-Chen Chang
Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate. Nature communications 13 (1) (2022)
Emily B Lancaster, Wanjie Yang, William H Johnson, Bert-Jan Baas, Yan Jessie Zhang, Christian P Whitman
Kinetic, Inhibition, and Structural Characterization of a Malonate Semialdehyde Decarboxylase-like Protein from Calothrix sp. PCC 6303: A Gateway to the non-Pro1 Tautomerase Superfamily Members. Biochemistry (2022)
Hongyuan Lu, Daniel J Diaz, Natalie J Czarnecki, Congzhi Zhu, Wantae Kim, Raghav Shroff, Daniel J Acosta, Bradley R Alexander, Hannah O Cole, Yan Jessie Zhang, Nathaniel A Lynd, Andrew D Ellington, Hal S Alper
Machine learning-aided engineering of hydrolases for PET depolymerization. Nature 604 (7907) (2022)
Bert-Jan Baas, Brenda P Medellin, Jake A LeVieux, Kaci Erwin, Emily B Lancaster, William H Johnson, Tamer S Kaoud, R Yvette Moreno, Marieke de Ruijter, Patricia C Babbitt, Yan Jessie Zhang, Christian P Whitman
Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications. Biochemistry 60 (22) (2021)
Blase M LeBlanc, Rosamaria Y Moreno, Edwin E Escobar, Mukesh Kumar Venkat Ramani, Jennifer S Brodbelt, Yan Jessie Zhang
What's all the phos about? Insights into the phosphorylation state of the RNA polymerase II C-terminal domain via mass spectrometry. RSC chemical biology 2 (4) (2021)
Edwin E Escobar, Mukesh Kumar Venkat Ramani, Yan Jessie Zhang, Jennifer S Brodbelt
Evaluating Spatiotemporal Dynamics of Phosphorylation of RNA Polymerase II Carboxy-Terminal Domain by Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Chemical Society 143 (22) (2021)
Brenda Medellin, Wanjie Yang, Srihari Konduri, Jiajun Dong, Seema Irani, Haoyi Wu, Wendy L Matthews, Zhong-Yin Zhang, Dionico Siegel, Yan Jessie Zhang
Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. Journal of medicinal chemistry 65 (1) (2021)
Brenda P Medellin, Emily B Lancaster, Shoshana D Brown, Swanand Rakhade, Patricia C Babbitt, Christian P Whitman, Yan Jessie Zhang
Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer. Biochemistry 59 (16) (2020)
Wei-Cheng Lu, Achinto Saha, Wupeng Yan, Kendra Garrison, Candice Lamb, Renu Pandey, Seema Irani, Alessia Lodi, Xiyuan Lu, Stefano Tiziani, Yan Jessie Zhang, George Georgiou, John DiGiovanni, Everett M Stone
Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proceedings of the National Academy of Sciences of the United States of America 117 (23) (2020)
Mukesh Kumar Venkat Ramani, Edwin E Escobar, Seema Irani, Joshua E Mayfield, Rosamaria Y Moreno, Jamie P Butalewicz, Victoria C Cotham, Haoyi Wu, Meena Tadros, Jennifer S Brodbelt, Yan Jessie Zhang
Structural Motifs for CTD Kinase Specificity on RNA Polymerase II during Eukaryotic Transcription. ACS chemical biology 15 (8) (2020)
Kanchan Aggarwal, Timothy P Kuka, Mandira Banik, Brenda P Medellin, Chinh Q Ngo, Da Xie, Yohaan Fernandes, Tyler L Dangerfield, Elva Ye, Bailey Bouley, Kenneth A Johnson, Yan Jessie Zhang, Johann K Eberhart, Emily L Que
Visible Light Mediated Bidirectional Control over Carbonic Anhydrase Activity in Cells and in Vivo Using Azobenzenesulfonamides. Journal of the American Chemical Society 142 (34) (2020)
Bert-Jan Baas, Brenda P Medellin, Jake A LeVieux, Marieke de Ruijter, Yan Jessie Zhang, Shoshana D Brown, Eyal Akiva, Patricia C Babbitt, Christian P Whitman
Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer. Biochemistry 58 (22) (2019)
Shao-An Wang, Yeonjin Ko, Jia Zeng, Yujie Geng, Daan Ren, Yasushi Ogasawara, Seema Irani, Yan Jessie Zhang, Hung-Wen Liu
Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis. Journal of the American Chemical Society 141 (15) (2019)
Joshua E Mayfield, Seema Irani, Edwin E Escobar, Zhao Zhang, Nathaniel T Burkholder, Michelle R Robinson, M Rachel Mehaffey, Sarah N Sipe, Wanjie Yang, Nicholas A Prescott, Karan R Kathuria, Zhijie Liu, Jennifer S Brodbelt, Yan Jessie Zhang
Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb. eLife 8 (2019)
Nathaniel T Burkholder, Sarah N Sipe, Edwin E Escobar, Mukeshkumar Venkatramani, Seema Irani, Wanjie Yang, Haoyi Wu, Wendy M Matthews, Jennifer S Brodbelt, Yan Jessie Zhang
Mapping RNAPII CTD Phosphorylation Reveals That the Identity and Modification of Seventh Heptad Residues Direct Tyr1 Phosphorylation. ACS chemical biology 14 (10) (2019)
Tyler M M Stack, Wenzong Li, William H Johnson, Yan Jessie Zhang, Christian P Whitman
Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry 57 (6) (2018)
Jake A LeVieux, Brenda Medellin, William H Johnson, Kaci Erwin, Wenzong Li, Ingrid A Johnson, Yan Jessie Zhang, Christian P Whitman
Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily. Biochemistry 57 (25) (2018)
Wupeng Yan, Everett M Stone, Yan Jessie Zhang
Structural Snapshots of an Engineered Cystathionine-γ-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site. Biochemistry 56 (6) (2017)
Joshua E Mayfield, Michelle R Robinson, Victoria C Cotham, Seema Irani, Wendy L Matthews, Anjana Ram, David S Gilmour, Joe R Cannon, Yan Jessie Zhang, Jennifer S Brodbelt
Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass Spectrometry. ACS chemical biology 12 (1) (2016)