Yang-Xin Fu

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 55

Top Venues

Nature communications

Clinical cancer research : an official journal of the American Association for Cancer Research

Cell research

Cellular & molecular immunology

University of Chicago Division of Biological Sciences

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Chicago Division of Biological Sciences

United States

professor :: pathology

Publications

Xuezhi Cao, Yang-Xin Fu, Hua Peng
Promising Cytokine Adjuvants for Enhancing Tuberculosis Vaccine Immunity. Vaccines 12 (5) (2024)
Hang Zhou, Wenjun Wang, Hairong Xu, Yong Liang, Jiyu Ding, Mengjie Lv, Boyang Ren, Hua Peng, Yang-Xin Fu, Mingzhao Zhu
Metabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy. Nature communications 15 (1) (2024)
Hang Zhou, Wenjun Wang, Hairong Xu, Yong Liang, Jiyu Ding, Mengjie Lv, Boyang Ren, Hua Peng, Yang-Xin Fu, Mingzhao Zhu
Metabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy. Nature communications 15 (1) (2024)
Zhuangzhi Zou, Jiao Shen, Diyuan Xue, Hongjia Li, Longxin Xu, Weian Cao, Wenyan Wang, Yang-Xin Fu, Hua Peng
Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8 + T cells for systemic antitumor responses. Nature communications 15 (1) (2024)
Zhenhua Ren, Xuhao Zhang, Yang-Xin Fu
Facts and Hopes on Chimeric Cytokine Agents for Cancer Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Jian Wang, Suxin Li, Maggie Wang, Xu Wang, Shuqing Chen, Zhichen Sun, Xiubao Ren, Gang Huang, Baran D Sumer, Nan Yan, Yang-Xin Fu, Jinming Gao
STING licensing of type I dendritic cells potentiates antitumor immunity. Science immunology 9 (92) (2024)
Zaopeng Yang, Yang-Xin Fu
Inactivation of TGF-β signaling in CAR-T cells. Cellular & molecular immunology 21 (3) (2024)
Zhuangzhi Zou, Jiao Shen, Diyuan Xue, Hongjia Li, Longxin Xu, Weian Cao, Wenyan Wang, Yang-Xin Fu, Hua Peng
Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8 + T cells for systemic antitumor responses. Nature communications 15 (1) (2024)
Jian Wang, Suxin Li, Maggie Wang, Xu Wang, Shuqing Chen, Zhichen Sun, Xiubao Ren, Gang Huang, Baran D Sumer, Nan Yan, Yang-Xin Fu, Jinming Gao
STING licensing of type I dendritic cells potentiates antitumor immunity. Science immunology 9 (92) (2024)
Xuezhi Cao, Yang-Xin Fu, Hua Peng
Promising Cytokine Adjuvants for Enhancing Tuberculosis Vaccine Immunity. Vaccines 12 (5) (2024)
Zaopeng Yang, Yang-Xin Fu
Inactivation of TGF-β signaling in CAR-T cells. Cellular & molecular immunology 21 (3) (2024)
Xuxiang Wang, Tengjiang Zhang, Bingxin Zheng, Youxue Lu, Yong Liang, Guoyuan Xu, Luyang Zhao, Yuwei Tao, Qianhui Song, Huiwen You, Haitian Hu, Xuan Li, Keyong Sun, Tianqi Li, Zian Zhang, Jianbian Wang, Xun Lan, Deng Pan, Yang-Xin Fu, Bin Yue, Hanqiu Zheng
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth. Nature cell biology (2024)
Jason Bugno, Liangliang Wang, Xianbin Yu, Xuezhi Cao, Jiaai Wang, Xiaona Huang, Kaiting Yang, Andras Piffko, Katherine Chen, Stephen Y Luo, Emile Naccasha, Yuzhu Hou, Sherry Fu, Chuan He, Yang-Xin Fu, Hua Laura Liang, Ralph R Weichselbaum
Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Zaopeng Yang, Yang-Xin Fu
Inactivation of TGF-β signaling in CAR-T cells. Cellular & molecular immunology (2024)
Zaopeng Yang, Yang-Xin Fu
Inactivation of TGF-β signaling in CAR-T cells. Cellular & molecular immunology 21 (3) (2024)
Zhenhua Ren, Xuhao Zhang, Yang-Xin Fu
Facts and Hopes on Chimeric Cytokine Agents for Cancer Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Jian Wang, Suxin Li, Maggie Wang, Xu Wang, Shuqing Chen, Zhichen Sun, Xiubao Ren, Gang Huang, Baran D Sumer, Nan Yan, Yang-Xin Fu, Jinming Gao
STING licensing of type I dendritic cells potentiates antitumor immunity. Science immunology 9 (92) (2024)
Jason Bugno, Liangliang Wang, Xianbin Yu, Xuezhi Cao, Jiaai Wang, Xiaona Huang, Kaiting Yang, Andras Piffko, Katherine Chen, Stephen Y Luo, Emile Naccasha, Yuzhu Hou, Sherry Fu, Chuan He, Yang-Xin Fu, Hua Laura Liang, Ralph R Weichselbaum
Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Xuxiang Wang, Tengjiang Zhang, Bingxin Zheng, Youxue Lu, Yong Liang, Guoyuan Xu, Luyang Zhao, Yuwei Tao, Qianhui Song, Huiwen You, Haitian Hu, Xuan Li, Keyong Sun, Tianqi Li, Zian Zhang, Jianbian Wang, Xun Lan, Deng Pan, Yang-Xin Fu, Bin Yue, Hanqiu Zheng
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth. Nature cell biology (2024)
Hang Zhou, Wenjun Wang, Hairong Xu, Yong Liang, Jiyu Ding, Mengjie Lv, Boyang Ren, Hua Peng, Yang-Xin Fu, Mingzhao Zhu
Metabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy. Nature communications 15 (1) (2024)
Jason Bugno, Liangliang Wang, Xianbin Yu, Xuezhi Cao, Jiaai Wang, Xiaona Huang, Kaiting Yang, Andras Piffko, Katherine Chen, Stephen Y Luo, Emile Naccasha, Yuzhu Hou, Sherry Fu, Chuan He, Yang-Xin Fu, Hua Laura Liang, Ralph R Weichselbaum
Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Zhuangzhi Zou, Jiao Shen, Diyuan Xue, Hongjia Li, Longxin Xu, Weian Cao, Wenyan Wang, Yang-Xin Fu, Hua Peng
Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8 + T cells for systemic antitumor responses. Nature communications 15 (1) (2024)
Zhuangzhi Zou, Jiao Shen, Diyuan Xue, Hongjia Li, Longxin Xu, Weian Cao, Wenyan Wang, Yang-Xin Fu, Hua Peng
Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8 + T cells for systemic antitumor responses. Nature communications 15 (1) (2024)
Hang Zhou, Wenjun Wang, Hairong Xu, Yong Liang, Jiyu Ding, Mengjie Lv, Boyang Ren, Hua Peng, Yang-Xin Fu, Mingzhao Zhu
Metabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy. Nature communications 15 (1) (2024)
Zaopeng Yang, Yang-Xin Fu
Inactivation of TGF-β signaling in CAR-T cells. Cellular & molecular immunology 21 (3) (2024)
Jian Wang, Suxin Li, Maggie Wang, Xu Wang, Shuqing Chen, Zhichen Sun, Xiubao Ren, Gang Huang, Baran D Sumer, Nan Yan, Yang-Xin Fu, Jinming Gao
STING licensing of type I dendritic cells potentiates antitumor immunity. Science immunology 9 (92) (2024)
Zhenhua Ren, Xuhao Zhang, Yang-Xin Fu
Facts and hopes on chimeric cytokine agents for cancer immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Hua Peng, Yang-Xin Fu
Towards developing a variant-proof SARS-CoV-2 vaccine. Cell research 33 (1) (2023)
Yuankun Zhang, Qingxiao Song, Kaniel Cassady, Michael Lee, Haidong Tang, Moqian Zheng, Bixin Wang, Dustin E Schones, Yang-Xin Fu, Arthur D Riggs, Paul J Martin, Ru Feng, Defu Zeng
Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America 120 (16) (2023)
Xue Wang, Longchao Liu, Tao Yue, Zhichen Sun, Joonbeom Bae, Kuo-Fu Tseng, Anli Zhang, Jian Qiao, Yang-Xin Fu
Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8 + T cells. Signal transduction and targeted therapy 8 (1) (2023)
Hua Peng, Yang-Xin Fu
Towards developing a variant-proof SARS-CoV-2 vaccine. Cell research (2023)
Hua Peng, Yang-Xin Fu
Towards developing a variant-proof SARS-CoV-2 vaccine. Cell research 33 (1) (2023)
Guangna Liu, Nana Ma, Keman Cheng, Qingqing Feng, Xiaotu Ma, Yale Yue, Yao Li, Tianjiao Zhang, Xiaoyu Gao, Jie Liang, Lizhuo Zhang, Xinwei Wang, Zhenhua Ren, Yang-Xin Fu, Xiao Zhao, Guangjun Nie
Bacteria-derived nanovesicles enhance tumour vaccination by trained immunity. Nature nanotechnology (2023)
Hua Peng, Yang-Xin Fu
Towards developing a variant-proof SARS-CoV-2 vaccine. Cell research 33 (1) (2023)
Joonbeom Bae, Longchao Liu, Casey Moore, Eric Hsu, Anli Zhang, Zhenhua Ren, Zhichen Sun, Xue Wang, Jiankun Zhu, Jiao Shen, Jian Qiao, Yang-Xin Fu
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8 + T cells to overcome immunotherapy resistance in cancer. Nature cell biology 24 (12) (2022)
Fanlin Li, Huihui Zhang, Wanting Wang, Puyuan Yang, Yue Huang, Junshi Zhang, Yaping Yan, Yuan Wang, Xizhong Ding, Jie Liang, Xinyue Qi, Min Li, Ping Han, Xiaoqing Zhang, Xin Wang, Jiang Cao, Yang-Xin Fu, Xuanming Yang
T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies. Nature communications 13 (1) (2022)
Qiang Feng, Zhida Liu, Xuexin Yu, Tongyi Huang, Jiahui Chen, Jian Wang, Jonathan Wilhelm, Suxin Li, Jiwon Song, Wei Li, Zhichen Sun, Baran D Sumer, Bo Li, Yang-Xin Fu, Jinming Gao
Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nature communications 13 (1) (2022)
Kyung-Min Lee, Chang-Ching Lin, Alberto Servetto, Joonbeom Bae, Vishal Kandagatla, Dan Ye, Gun Min Kim, Dhivya R Sudhan, Saurabh Mendiratta, Paula I Gonzalez Ericsson, Justin M Balko, Jeon Lee, Spencer Barnes, Venkat S Malladi, Siamak Tabrizi, Sangeetha M Reddy, Seoyun Yum, Ching-Wei Chang, Katherine E Hutchinson, Susan E Yost, Yuan Yuan, Zhijian J Chen, Yang-Xin Fu, Ariella B Hanker, Carlos L Arteaga
Epigenetic Repression of STING by MYC Promotes Immune Evasion and Resistance to Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer. Cancer immunology research 10 (7) (2022)
Yunjia Zhang, Boxun Li, Sergio Cananzi, Chuanhui Han, Lei-Lei Wang, Yuhua Zou, Yang-Xin Fu, Gary C Hon, Chun-Li Zhang
A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum. Proceedings of the National Academy of Sciences of the United States of America 119 (11) (2022)
Jiao Shen, Zhuangzhi Zou, Jingya Guo, Yueqi Cai, Diyuan Xue, Yong Liang, Wenyan Wang, Hua Peng, Yang-Xin Fu
An engineered concealed IL-15-R elicits tumor-specific CD8+T cell responses through PD-1-cis delivery. The Journal of experimental medicine 219 (12) (2022)
Longchao Liu, Jiahui Chen, Hongyi Zhang, Jianfeng Ye, Casey Moore, Changzheng Lu, Yan Fang, Yang-Xin Fu, Bo Li
Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity. Nature cancer 3 (4) (2022)
Diyuan Xue, Benjamin Moon, Jing Liao, Jingya Guo, Zhuangzhi Zou, Yanfei Han, Shuaishuai Cao, Yang Wang, Yang-Xin Fu, Hua Peng
A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors. Science immunology 7 (67) (2022)
Yong Liang, Raquibul Hannan, Yang-Xin Fu
Type I IFN Activating Type I Dendritic Cells for Antitumor Immunity. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (14) (2021)
Raquibul Hannan, Osama Mohamad, Alberto Diaz de Leon, Subrata Manna, Laurentiu M Pop, Ze Zhang, Samantha Mannala, Alana Christie, Scott Christley, Nancy Monson, Dan Ishihara, Eric J Hsu, Chul Ahn, Payal Kapur, Mingyi Chen, Yull Arriaga, Kevin Dale Courtney, Brandi L Cantarel, Edward K Wakeland, Yang-Xin Fu, Ivan Pedrosa, Lindsay Cowell, Tao Wang, Vitaly Margulis, Hak Choy, Robert D Timmerman, James Brugarolas
Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Shiyu Sun, Yueqi Cai, Tian-Zhang Song, Yang Pu, Lin Cheng, Hairong Xu, Jing Sun, Chaoyang Meng, Yifan Lin, Haibin Huang, Fang Zhao, Silin Zhang, Yu Gao, Jian-Bao Han, Xiao-Li Feng, Dan-Dan Yu, Yalan Zhu, Pu Gao, Haidong Tang, Jincun Zhao, Zheng Zhang, Jiaming Yang, Zhenxiang Hu, Yang-Xin Fu, Yong-Tang Zheng, Hua Peng
Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2. Cell research 31 (9) (2021)
Xuezhi Cao, Yong Liang, Zhenxiang Hu, Huiyu Li, Jiaming Yang, Eric J Hsu, Jiankun Zhu, Jin Zhou, Yang-Xin Fu
Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance. Nature communications 12 (1) (2021)
Jingya Guo, Yong Liang, Diyuan Xue, Jiao Shen, Yueqi Cai, Jiankun Zhu, Yang-Xin Fu, Hua Peng
Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity. Cell research 31 (11) (2021)
Shiyu Sun, Xi Chen, Jingjing Lin, Junwen Ai, Jiaming Yang, Zhenxiang Hu, Yang-Xin Fu, Hua Peng
Broad neutralization against SARS-CoV-2 variants induced by a next-generation protein vaccine V-01. Cell discovery 7 (1) (2021)
Anli Zhang, Zhenhua Ren, Kuo-Fu Tseng, Xiaojuan Liu, Huiyu Li, Changzheng Lu, Yueqi Cai, John D Minna, Yang-Xin Fu
Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors. Science translational medicine 13 (605) (2021)
Longchao Liu, Jiahui Chen, Joonbeom Bae, Huiyu Li, Zhichen Sun, Casey Timmerman, Eric J Hsu, Chuanhui Han, Jian Qiao, Yang-Xin Fu
Rejuvenation of tumour-specific T cells through bispecific antibodies targeting PD-L1 on dendritic cells. Nature biomedical engineering 5 (11) (2021)
Eric J Hsu, Xuezhi Cao, Benjamin Moon, Joonbeom Bae, Zhichen Sun, Zhida Liu, Yang-Xin Fu
A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy. Nature communications 12 (1) (2021)
Yong Wang, Maowu Luo, Yan Chen, Bo Zhang, Zhenhua Ren, Lei Bao, Jennifer E Wang, Yang-Xin Fu, Yingfei Wang
ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer research 81 (1) (2020)
Wenxin Zheng, Diana Rose E Ranoa, Xiaona Huang, Yuzhu Hou, Kaiting Yang, Elizabeth C Poli, Michael A Beckett, Yang-Xin Fu, Ralph R Weichselbaum
RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy. Cancer research 80 (24) (2020)
Hongyi Zhang, Longchao Liu, Jian Zhang, Jiahui Chen, Jianfeng Ye, Sachet A Shukla, Jian Qiao, Xiaowei Zhan, Hao Chen, Catherine J Wu, Yang-Xin Fu, Bo Li
Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (6) (2019)
Joanna A Wroblewska, Yuan Zhang, Haidong Tang, Xiaohuan Guo, Cathryn Nagler, Yang-Xin Fu
Cutting Edge: Lymphotoxin Signaling Is Essential for Clearance of Salmonella from the Gut Lumen and Generation of Anti-Salmonella Protective Immunity. Journal of immunology (Baltimore, Md. : 1950) 198 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Yang-Xin Fu