Alessandro Bonifazi

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 38

Top Venues

Journal of medicinal chemistry

ACS chemical neuroscience

bioRxiv : the preprint server for biology

Research square

National Institute on Drug Abuse Medicinal Chemistry Section

University of Camerino (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institute on Drug Abuse Medicinal Chemistry Section Jun 01 2014

United States

Post-Doctoral Fellow

Education History

University of Camerino

Italy

MSC :: School of Pharmacy - Scuola di Scienze del Farmaco e dei Prodotti della Salute

Publications

Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky, Margaret K Hahn, Gary J Schwartz, Barbara S Slusher, Amy Hauck Newman, Zachary Z Freyberg
Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia. bioRxiv : the preprint server for biology (2024)
Ana Semeano, Rian Garland, Alessandro Bonifazi, Kuo Hao Lee, John Famiglietti, Wenqi Zhang, Yoon Jae Jo, Francisco O Battiti, Lei Shi, Amy Hauck Newman, Hideaki Yano
Linkers in Bitopic Agonists Shape Bias Profile among Transducers for the Dopamine D2 and D3 Receptors. ACS pharmacology & translational science 7 (8) (2024)
Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky, Margaret K Hahn, Gary J Schwartz, Barbara S Slusher, Amy Hauck Newman, Zachary Z Freyberg
Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia. bioRxiv : the preprint server for biology (2024)
Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky, Margaret K Hahn, Gary J Schwartz, Barbara S Slusher, Amy Hauck Newman, Zachary Z Freyberg
Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia. bioRxiv : the preprint server for biology (2024)
Ana Semeano, Rian Garland, Alessandro Bonifazi, Kuo Hao Lee, John Famiglietti, Wenqi Zhang, Yoon Jae Jo, Francisco O Battiti, Lei Shi, Amy Hauck Newman, Hideaki Yano
Linkers in Bitopic Agonists Shape Bias Profile among Transducers for the Dopamine D2 and D3 Receptors. ACS pharmacology & translational science 7 (8) (2024)
Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky, Margaret K Hahn, Gary J Schwartz, Barbara S Slusher, Amy Hauck Newman, Zachary Z Freyberg
Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia. bioRxiv : the preprint server for biology (2024)
Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky, Margaret K Hahn, Gary J Schwartz, Barbara S Slusher, Amy Hauck Newman, Zachary Z Freyberg
Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia. bioRxiv : the preprint server for biology (2024)
Ana Semeano, Rian Garland, Alessandro Bonifazi, Kuo Hao Lee, John Famiglietti, Wenqi Zhang, Yoon Jae Jo, Francisco O Battiti, Lei Shi, Amy Hauck Newman, Hideaki Yano
Linkers in Bitopic Agonists Shape Bias Profile among Transducers for the Dopamine D2 and D3 Receptors. ACS pharmacology & translational science 7 (8) (2024)
Gianfabio Giorgioni, Alessandro Bonifazi, Luca Botticelli, Carlo Cifani, Federica Matteucci, Emanuela Micioni Di Bonaventura, Maria Vittoria Micioni Di Bonaventura, Mario Giannella, Alessandro Piergentili, Alessia Piergentili, Wilma Quaglia, Fabio Del Bello
Advances in drug design and therapeutic potential of selective or multitarget 5-HT1A receptor ligands. Medicinal research reviews (2024)
Alessandro Bonifazi, Michael Ellenberger, Zachary J Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O Mantilla-Rivas, Comfort A Boateng, Amy J Eshleman, Aaron Janowsky, Margaret K Hahn, Gary J Schwartz, Barbara S Slusher, Amy Hauck Newman, Zachary Z Freyberg
Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia. bioRxiv : the preprint server for biology (2024)
Sandra Arroyo-Urea, Antonina L Nazarova, Ángela Carrión-Antolí, Alessandro Bonifazi, Francisco O Battiti, Jordy Homing Lam, Amy Hauck Newman, Vsevolod Katritch, Javier García-Nafría
A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site. Nature communications 15 (1) (2024)
Sandra Arroyo-Urea, Antonina L Nazarova, Ángela Carrión-Antolí, Alessandro Bonifazi, Francisco O Battiti, Jordy Homing Lam, Amy Hauck Newman, Vsevolod Katritch, Javier García-Nafría
Structure of the dopamine D3 receptor bound to a bitopic agonist reveals a new specificity site in an expanded allosteric pocket. Research square (2023)
Javier García-Nafría, Sandra Arroyo-Urea, Antonina Nazarova, Ángela Carrión-Antolí, Alessandro Bonifazi, Francisco Battiti, Jordy Homing Lam, Amy Hauck Newman, Vsevolod Katritch
Structure of the dopamine D3 receptor bound to a bitopic agonist reveals a new specificity site in an expanded allosteric pocket. Research square (2023)
Comfort A Boateng, Ashley N Nilson, Rebekah Placide, Mimi L Pham, Franziska M Jakobs, Noelia M Boldizsar, Scot McIntosh, Leia S Stallings, Ivana V Korankyi, Shreya Kelshikar, Nisha Shah, Diandra Panasis, Abigail Muccilli, Maria Ladik, Brianna Maslonka, Connor McBride, Moises Ximello Sanchez, Ebrar Akca, Mohammad Alkhatib, Julianna Saez, Catherine Nguyen, Emily Kurtyan, Jacquelyn DePierro, Raymond Crowthers, Dylan Brunt, Alessandro Bonifazi, Amy Hauck Newman, Rana Rais, Barbara S Slusher, R Benjamin Free, David R Sibley, Kent D Stewart, Chun Wu, Scott E Hemby, Thomas M Keck
Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder. Journal of medicinal chemistry (2023)
Alessandro Bonifazi, Fabio Del Bello, Gianfabio Giorgioni, Alessandro Piergentili, Elizabeth Saab, Luca Botticelli, Carlo Cifani, Emanuela Micioni Di Bonaventura, Maria Vittoria Micioni Di Bonaventura, Wilma Quaglia
Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders. Medicinal research reviews (2023)
Sandra Arroyo-Urea, Antonina L Nazarova, Ángela Carrión-Antolí, Alessandro Bonifazi, Francisco O Battiti, Jordy Homing Lam, Amy Hauck Newman, Vsevolod Katritch, Javier García-Nafría
Structure of the dopamine D3 receptor bound to a bitopic agonist reveals a new specificity site in an expanded allosteric pocket. Research square (2023)
Emma S Gogarnoiu, Caleb D Vogt, Julie Sanchez, Alessandro Bonifazi, Elizabeth Saab, Anver Basha Shaik, Omar Soler-Cedeño, Guo-Hua Bi, Benjamin Klein, Zheng-Xiong Xi, J Robert Lane, Amy Hauck Newman
Dopamine D 3 /D 2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders. Journal of medicinal chemistry (2023)
Emma S Gogarnoiu, Caleb D Vogt, Julie Sanchez, Alessandro Bonifazi, Elizabeth Saab, Anver Basha Shaik, Omar Soler-Cedeño, Guo-Hua Bi, Benjamin Klein, Zheng-Xiong Xi, J Robert Lane, Amy Hauck Newman
Dopamine D 3 /D 2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders. Journal of medicinal chemistry 66 (3) (2023)
Sandra Arroyo-Urea, Antonina L Nazarova, Ángela Carrión-Antolí, Alessandro Bonifazi, Francisco O Battiti, Jordy Homing Lam, Amy Hauck Newman, Vsevolod Katritch, Javier García-Nafría
Structure of the dopamine D3 receptor bound to a bitopic agonist reveals a new specificity site in an expanded allosteric pocket. Research square (2023)
Emma S Gogarnoiu, Caleb D Vogt, Julie Sanchez, Alessandro Bonifazi, Elizabeth Saab, Anver Basha Shaik, Omar Soler-Cedeño, Guo-Hua Bi, Benjamin Klein, Zheng-Xiong Xi, J Robert Lane, Amy Hauck Newman
Dopamine D 3 /D 2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders. Journal of medicinal chemistry 66 (3) (2023)
Emma S Gogarnoiu, Caleb D Vogt, Julie Sanchez, Alessandro Bonifazi, Elizabeth Saab, Anver Basha Shaik, Omar Soler-Cedeño, Guo-Hua Bi, Benjamin Klein, Zheng-Xiong Xi, J Robert Lane, Amy Hauck Newman
Dopamine D 3 /D 2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders. Journal of medicinal chemistry 66 (3) (2023)
Alessandro Bonifazi, Elizabeth Saab, Julie Sanchez, Antonina L Nazarova, Saheem A Zaidi, Khorshada Jahan, Vsevolod Katritch, Meritxell Canals, J Robert Lane, Amy Hauck Newman
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics. Journal of medicinal chemistry (2023)
Pegi Pavletić, Ana Semeano, Hideaki Yano, Alessandro Bonifazi, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Maria Giovanna Sabbieti, Dimitrios Agas, Giorgio Santoni, Roberto Pallini, Lucia Ricci-Vitiani, Emanuela Sabato, Vistoli Giulio, Fabio Del Bello
Highly Potent and Selective Dopamine D 4 Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma. Journal of medicinal chemistry 65 (18) (2022)
Pramisha Adhikari, Bing Xie, Ana Semeano, Alessandro Bonifazi, Francisco O Battiti, Amy H Newman, Hideaki Yano, Lei Shi
Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor. Biomolecules 11 (4) (2021)
Anver Basha Shaik, Comfort A Boateng, Francisco O Battiti, Alessandro Bonifazi, Jianjing Cao, Li Chen, Rezvan Chitsazi, Saiprasad Ravi, Kuo Hao Lee, Lei Shi, Amy Hauck Newman
Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D2/D3 Receptor Bitopic Ligands. Journal of medicinal chemistry 64 (20) (2021)
Francisco O Battiti, Saheem A Zaidi, Vsevolod Katritch, Amy Hauck Newman, Alessandro Bonifazi
Chiral Cyclic Aliphatic Linkers as Building Blocks for Selective Dopamine D2 or D3 Receptor Agonists. Journal of medicinal chemistry 64 (21) (2021)
Alessandro Bonifazi, Francisco O Battiti, Julie Sanchez, Saheem A Zaidi, Eric Bow, Mariia Makarova, Jianjing Cao, Anver Basha Shaik, Agnieszka Sulima, Kenner C Rice, Vsevolod Katritch, Meritxell Canals, J Robert Lane, Amy Hauck Newman
Novel Dual-Target μ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management. Journal of medicinal chemistry 64 (11) (2021)
Alessandro Bonifazi, Amy Hauck Newman, Thomas M Keck, Silvia Gervasoni, Vistoli Giulio, Fabio Del Bello, Gianfabio Giorgioni, Pegi Pavletić, Wilma Quaglia, Alessandro Piergentili
Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders. ACS chemical neuroscience 12 (19) (2021)
Amy E Moritz, Alessandro Bonifazi, Adrian M Guerrero, Vivek Kumar, R Benjamin Free, J Robert Lane, Ravi Kumar Verma, Lei Shi, Amy Hauck Newman, David R Sibley
Evidence for a Stereoselective Mechanism for Bitopic Activity by Extended-Length Antagonists of the D3 Dopamine Receptor. ACS chemical neuroscience 11 (20) (2020)
Carlo Cifani, Emanuela Micioni Di Bonaventura, Luca Botticelli, Fabio Del Bello, Gianfabio Giorgioni, Pegi Pavletić, Alessandro Piergentili, Wilma Quaglia, Alessandro Bonifazi, Dirk Schepmann, Bernhard Wünsch, Vistoli Giulio, Maria Vittoria Micioni Di Bonaventura
Novel Highly Potent and Selective Sigma1 Receptor Antagonists Effectively Block the Binge Eating Episode in Female Rats. ACS chemical neuroscience 11 (19) (2020)
Fabio Del Bello, Alessandro Bonifazi, Gianfabio Giorgioni, Alessandro Piergentili, Maria Giovanna Sabbieti, Dimitrios Agas, Marzia Dell'Aera, Rosanna Matucci, Marcin Górecki, Gennaro Pescitelli, Vistoli Giulio, Wilma Quaglia
Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus. Journal of medicinal chemistry 63 (11) (2020)
Daryl A Guthrie, Carmen Klein Herenbrink, Matthew Domenic Lycas, Therese C Ku, Alessandro Bonifazi, Brian T DeVree, Signe Mathiasen, Jonathan A Javitch, Jonathan B Grimm, Luke D Lavis, Ulrik Gether, Amy Hauck Newman
Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter. ACS chemical neuroscience 11 (20) (2020)
Amy Hauck Newman, Francisco O Battiti, Alessandro Bonifazi
2016 Philip S. Portoghese Medicinal Chemistry Lectureship: Designing Bivalent or Bitopic Molecules for G-Protein Coupled Receptors. The Whole Is Greater Than the Sum of Its Parts. Journal of medicinal chemistry 63 (5) (2019)
Anver Basha Shaik, Vivek Kumar, Alessandro Bonifazi, Adrian M Guerrero, Sophie L Cemaj, Alexandra Gadiano, Jenny Lam, Zheng-Xiong Xi, Rana Rais, Barbara S Slusher, Amy Hauck Newman
Investigation of Novel Primary and Secondary Pharmacophores and 3-Substitution in the Linking Chain of a Series of Highly Selective and Bitopic Dopamine D3 Receptor Antagonists and Partial Agonists. Journal of medicinal chemistry 62 (20) (2019)
Rachel D Slack, Ara M Abramyan, Helen Tang, Sitaram Meena, Bruce A Davis, Alessandro Bonifazi, JoLynn B Giancola, Jeffrey R Deschamps, Sett Naing, Hideaki Yano, Satinder K Singh, Amy Hauck Newman, Lei Shi
A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter. ACS chemical neuroscience 10 (9) (2019)
Rachel D Slack, Therese C Ku, Jianjing Cao, JoLynn B Giancola, Alessandro Bonifazi, Claus J Loland, Alexandra Gadiano, Jenny Lam, Rana Rais, Barbara S Slusher, Mark Coggiano, Gianluigi Tanda, Amy Hauck Newman
Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic Stability. Journal of medicinal chemistry 63 (5) (2019)
Fabio Del Bello, Maria Vittoria Micioni Di Bonaventura, Alessandro Bonifazi, Bernhard Wünsch, Dirk Schepmann, JoLynn B Giancola, Emanuela Micioni Di Bonaventura, Vistoli Giulio, Gianfabio Giorgioni, Wilma Quaglia, Alessandro Piergentili, Carlo Cifani
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane. ACS chemical neuroscience 10 (8) (2019)
Francisco O Battiti, Sophie L Cemaj, Adrian M Guerrero, Anver Basha Shaik, Jenny Lam, Rana Rais, Barbara S Slusher, Jeffery R Deschamps, Greg H Imler, Amy Hauck Newman, Alessandro Bonifazi
The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D3 Receptor (D3R) Selective Agonists. Journal of medicinal chemistry 62 (13) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Alessandro Bonifazi