Adam Yasgar

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Venues

ACS pharmacology & translational science

Journal of medicinal chemistry

Proceedings of the National Academy of Sciences of the United States of America

Journal of chemical information and modeling

National Center for Advancing Translational Sciences

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Center for Advancing Translational Sciences Aug 01 2005

United States

Scientist :: DPI

Pfizer Global Research and Development

United States

Drug Metabolism Scientist/Bioanalytical Scientist :: DMPK

Publications

Kalyan Golla, Adam Yasgar, Voddarahally N Manjuprasanna, Meghna U Naik, Bolormaa Baljinnyam, Alexey V Zakharov, Sankalp Jain, Ganesha Rai, Ajit Jadhav, Anton Simeonov, Ulhas P Naik
Small-Molecule Disruptors of the Interaction between Calcium- and Integrin-Binding Protein 1 and Integrin α IIb β 3 as Novel Antiplatelet Agents. ACS pharmacology & translational science 7 (7) (2024)
Kalyan Golla, Adam Yasgar, Voddarahally N Manjuprasanna, Meghna U Naik, Bolormaa Baljinnyam, Alexey V Zakharov, Sankalp Jain, Ganesha Rai, Ajit Jadhav, Anton Simeonov, Ulhas P Naik
Small-Molecule Disruptors of the Interaction between Calcium- and Integrin-Binding Protein 1 and Integrin α IIb β 3 as Novel Antiplatelet Agents. ACS pharmacology & translational science 7 (7) (2024)
Vinicius M Alves, Adam Yasgar, James Wellnitz, Ganesha Rai, Marielle Rath, Rodolpho C Braga, Stephen J Capuzzi, Anton Simeonov, Eugene N Muratov, Alexey V Zakharov, Alexander Trospsha
Lies and Liabilities: Computational Assessment of High-Throughput Screening Hits to Identify Artifact Compounds. Journal of medicinal chemistry (2023)
Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov
Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science 6 (5) (2023)
Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov
Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science 6 (5) (2023)
Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov
Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science 6 (5) (2023)
Haider H Dar, Karolina Mikulska-Ruminska, Yulia Y Tyurina, Diane K Luci, Adam Yasgar, Svetlana N Samovich, Alexander A Kapralov, Austin B Souryavong, Vladimir A Tyurin, Andrew A Amoscato, Michael W Epperly, Galina V Shurin, Melissa Standley, Theodore R Holman, Claudette M St Croix, Simon C Watkins, Andrew P VanDemark, Sandeep Rana, Alexey V Zakharov, Anton Simeonov, Juan Jose Marugan, Rama K Mallampalli, Sally E Wentzel, Joel S Greenberger, Ganesha Rai, Hülya Bayir, Ivet Bahar, Valerian E Kagan
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators. Proceedings of the National Academy of Sciences of the United States of America 120 (25) (2023)
Pengfei Yu, Shuwen Cao, Shyh-Ming Yang, Ganesha Rai, Natalia J Martinez, Adam Yasgar, Alexey V Zakharov, Anton Simeonov, William A Molina-Arocho, Graham P Lobel, Hesham Mohei, Alexis L Scott, Li Zhai, Emma E Furth, M Celeste Simon, Malay Haldar
RALDH1 inhibition shows immunotherapeutic efficacy in hepatocellular carcinoma. Cancer immunology research (2023)
Guangping Dong, Youchao Deng, Adam Yasgar, Ravi Yadav, Daniel Talley, Alexey V Zakharov, Sankalp Jain, Ganesha Rai, Nicholas Noinaj, Anton Simeonov, Rong Huang
Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner. Journal of medicinal chemistry 65 (18) (2022)
Dorjbal Dorjsuren, Richard T Eastman, Min Jae Song, Adam Yasgar, Yuchi Chen, Kapil Bharti, Alexey V Zakharov, Ajit Jadhav, Marc Ferrer, Pei-Yong Shi, Anton Simeonov
A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model. PloS one 17 (1) (2022)
Jason M Rohde, Surendra Karavadhi, Rajan Pragani, Li Liu, Yuhong Fang, Weihe Zhang, Andrew McIver, Hongchao Zheng, Qingyang Liu, Mindy I Davis, Daniel J Urban, Tobie D Lee, Dorian M Cheff, Melinda Hollingshead, Mark J Henderson, Natalia J Martinez, Kyle R Brimacombe, Adam Yasgar, Wei Zhao, Carleen Klumpp-Thomas, Sam Michael, Joseph Covey, William J Moore, Gordon M Stott, Zhuyin Li, Anton Simeonov, Ajit Jadhav, Stephen V Frye, Matthew D Hall, Min Shen, Xiaodong Wang, Samarjit Patnaik, Matthew B Boxer
Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer. Journal of medicinal chemistry 64 (8) (2021)
Guangping Dong, Adam Yasgar, Darrell L Peterson, Alexey V Zakharov, Daniel Talley, Ken Chih-Chien Cheng, Ajit Jadhav, Anton Simeonov, Rong Huang
Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors. ACS combinatorial science 22 (8) (2020)
Theresa D Manz, Sindhu Carmen Sivakumaren, Fleur M Ferguson, Tinghu Zhang, Adam Yasgar, Hyuk-Soo Seo, Scott B Ficarro, Joseph D Card, Hyeseok Shim, Chandrasekhar V Miduturu, Anton Simeonov, Min Shen, Jarrod A Marto, Sirano Dhe-Paganon, Matthew D Hall, Lewis C Cantley, Nathanael S Gray
Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of medicinal chemistry 63 (9) (2020)
Ann M Richard, Ruili Huang, Suramya Waidyanatha, Paul Shinn, Bradley J Collins, Inthirany Thillainadarajah, Christopher M Grulke, Antony J Williams, Ryan R Lougee, Richard S Judson, Keith A Houck, Mahmoud Shobair, Chihae Yang, James F Rathman, Adam Yasgar, Suzanne C Fitzpatrick, Anton Simeonov, Russell S Thomas, Kevin M Crofton, Richard S Paules, John R Bucher, Christopher P Austin, Robert J Kavlock, Raymond R Tice
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology. Chemical research in toxicology 34 (2) (2020)
Rachel P M Abrams, Adam Yasgar, Tadahisa Teramoto, Myoung-Hwa Lee, Dorjbal Dorjsuren, Richard T Eastman, Nasir Malik, Alexey V Zakharov, Wenxue Li, Muzna Bachani, Kyle Brimacombe, Joseph P Steiner, Matthew D Hall, Anuradha Balasubramanian, Ajit Jadhav, Radhakrishnan Padmanabhan, Anton Simeonov, Avindra Nath
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America 117 (49) (2020)
Vinicius M Alves, Stephen J Capuzzi, Rodolpho C Braga, Daniel Korn, Joshua E Hochuli, Kyle H Bowler, Adam Yasgar, Ganesha Rai, Anton Simeonov, Eugene N Muratov, Alexey V Zakharov, Alexander Trospsha
SCAM Detective: Accurate Predictor of Small, Colloidally Aggregating Molecules. Journal of chemical information and modeling 60 (8) (2020)
Alexey V Zakharov, Tongan Zhao, Dac-Trung Nguyen, Tyler Peryea, Timothy Sheils, Adam Yasgar, Ruili Huang, Noel Southall, Anton Simeonov
Novel Consensus Architecture To Improve Performance of Large-Scale Multitask Deep Learning QSAR Models. Journal of chemical information and modeling 59 (11) (2019)
Michael H Ronzetti, Bolormaa Baljinnyam, Adam Yasgar, Anton Simeonov
Testing for drug-human serum albumin binding using fluorescent probes and other methods. Expert opinion on drug discovery 13 (11) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Adam Yasgar