Amedeo Caflisch (A Caflisch)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 48

Top Venues

Journal of chemical information and modeling

ACS bio & med chem Au

Journal of medicinal chemistry

Journal of chemical theory and computation

ETH Zurich (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

ETH Zurich

Switzerland

PHD

Publications

Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi, Jiahua Deng, Dylan Coelho, Emmanuelle Braud, Laura Iannazzo, Yaozong Li, Danzhi Huang, Mélanie Ethève-Quelquejeu, Qiang Cui, Amedeo Caflisch
The catalytic mechanism of the RNA methyltransferase METTL3. eLife 12 (2024)
František Zálešák, Francesco Nai, Marcin Herok, Elena Bochenkova, Rajiv Kumar Bedi, Yaozong Li, Francesco Errani, Amedeo Caflisch
Structure-Based Design of a Potent and Selective YTHDC1 Ligand. Journal of medicinal chemistry 67 (11) (2024)
František Zálešák, Francesco Nai, Marcin Herok, Elena Bochenkova, Rajiv Kumar Bedi, Yaozong Li, Francesco Errani, Amedeo Caflisch
Structure-Based Design of a Potent and Selective YTHDC1 Ligand. Journal of medicinal chemistry (2024)
František Zálešák, Francesco Nai, Marcin Herok, Elena Bochenkova, Rajiv Kumar Bedi, Yaozong Li, Francesco Errani, Amedeo Caflisch
Structure-Based Design of a Potent and Selective YTHDC1 Ligand. Journal of medicinal chemistry 67 (11) (2024)
František Zálešák, Francesco Nai, Marcin Herok, Elena Bochenkova, Rajiv Kumar Bedi, Yaozong Li, Francesco Errani, Amedeo Caflisch
Structure-Based Design of a Potent and Selective YTHDC1 Ligand. Journal of medicinal chemistry 67 (11) (2024)
Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi, Jiahua Deng, Dylan Coelho, Emmanuelle Braud, Laura Iannazzo, Yaozong Li, Danzhi Huang, Mélanie Ethève-Quelquejeu, Qiang Cui, Amedeo Caflisch
The catalytic mechanism of the RNA methyltransferase METTL3. eLife 12 (2024)
Francesco Errani, Annalisa Invernizzi, Marcin Herok, Elena Bochenkova, Fiona Stamm, Ivan Corbeski, Valeria Romanucci, Giovanni Di Fabio, František Zálešák, Amedeo Caflisch
Proteolysis Targeting Chimera Degraders of the METTL3-14 m 6 A-RNA Methyltransferase. JACS Au 4 (2) (2024)
Francesco Errani, Annalisa Invernizzi, Marcin Herok, Elena Bochenkova, Fiona Stamm, Ivan Corbeski, Valeria Romanucci, Giovanni Di Fabio, František Zálešák, Amedeo Caflisch
Proteolysis Targeting Chimera Degraders of the METTL3-14 m 6 A-RNA Methyltransferase. JACS Au 4 (2) (2024)
Wonmuk Hwang, Steven L Austin, Arnaud Blondel, Eric D Boittier, Stefan Boresch, Matthias Buck, Joshua Buckner, Amedeo Caflisch, Hao-Ting Chang, Xi Cheng, Yeol Kyo Choi, Jhih-Wei Chu, Michael F Crowley, Qiang Cui, Ana Damjanovic, Yuqing Deng, Michael Devereux, Xinqiang Ding, Michael F Feig, Jiali Gao, David R Glowacki, James E Gonzales, Mehdi Bagerhi Hamaneh, Edward D Harder, Ryan L Hayes, Jing Huang, Yandong Huang, Phillip S Hudson, Wonpil Im, Shahidul M Islam, Wei Jiang, Michael R Jones, Silvan Käser, Fiona L Kearns, Nathan R Kern, Jeffery B Klauda, Themis Lazaridis, Jinhyuk Lee, Justin A Lemkul, Xiaorong Liu, Yun Lyna Luo, Alexander D MacKerell, Dan Thomas Major, Markus Meuwly, Kwangho Nam, Lennart Nilsson, Victor Ovchinnikov, Emanuele Paci, Soohyung Park, Richard W Pastor, Amanda R Pittman, Carol Beth Post, Samarjeet Prasad, Jingzhi Pu, John Z H Zhang, Thenmalarchelvi Rathinavelan, Daniel R Roe, Benoı T Roux, Christopher N Rowley, Jana Shen, Andrew C Simmonett, Alexander J Sodt, Kai Töpfer, Meenu Upadhyay, Arjan van der Vaart, Luis Itza Vazquez-Salazar, Richard M Venable, Luke C Warrensford, H Lee Woodcock, Yujin Wu, Charles L Brooks Iii, Bernard R Brooks, Martin Karplus
CHARMM at 45: Enhancements in Accessibility, Functionality, and Speed. The journal of physical chemistry. B (2024)
Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi, Jiahua Deng, Dylan Coelho, Emmanuelle Braud, Laura Iannazzo, Yaozong Li, Danzhi Huang, Mélanie Ethève-Quelquejeu, Qiang Cui, Amedeo Caflisch
The catalytic mechanism of the RNA methyltransferase METTL3. eLife 12 (2024)
Francesco Nai, Maria Paula Flores Espinoza, Annalisa Invernizzi, Pablo Andrés Vargas-Rosales, Olga Bobileva, Marcin Herok, Amedeo Caflisch
Small-Molecule Inhibitors of the m7G-RNA Writer METTL1. ACS bio & med chem Au 4 (2) (2023)
Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi, Jiahua Deng, Dylan Coelho, Emmanuelle Braud, Laura Iannazzo, Yaozong Li, Danzhi Huang, Mélanie Ethève-Quelquejeu, Qiang Cui, Amedeo Caflisch
The catalytic mechanism of the RNA methyltransferase METTL3. bioRxiv : the preprint server for biology (2023)
Francesco Nai, Maria Paula Flores Espinoza, Annalisa Invernizzi, Pablo Andrés Vargas-Rosales, Olga Bobileva, Marcin Herok, Amedeo Caflisch
Small-Molecule Inhibitors of the m7G-RNA Writer METTL1. ACS bio & med chem Au 4 (2) (2023)
Francesco Nai, Maria Paula Flores Espinoza, Annalisa Invernizzi, Pablo Andrés Vargas-Rosales, Olga Bobileva, Marcin Herok, Amedeo Caflisch
Small-Molecule Inhibitors of the m7G-RNA Writer METTL1. ACS bio & med chem Au 4 (2) (2023)
Rajiv Kumar Bedi, Danzhi Huang, Yaozong Li, Amedeo Caflisch
Structure-Based Design of Inhibitors of the m 6 A-RNA Writer Enzyme METTL3. ACS bio & med chem Au 3 (4) (2023)
Julian Widmer, Cassiano Langini, Andreas Vitalis, Amedeo Caflisch
Optimized reaction coordinates for analysis of enhanced sampling. The Journal of chemical physics 159 (1) (2023)
Raitis Bobrovs, Laura Drunka, Iveta Kanepe, Aigars Jirgensons, Amedeo Caflisch, Matteo Salvalaglio, Kristaps Jaudzems
Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors. Journal of chemical information and modeling (2023)
Pablo Andrés Vargas-Rosales, Alessio D'Addio, Yang Zhang, Amedeo Caflisch
Disrupting Dimeric β-Amyloid by Electric Fields. ACS physical chemistry Au 3 (5) (2023)
Ioana M Ilie, Claus Ehrhardt, Amedeo Caflisch, Gabriele Weitz-Schmidt
Decrypting Integrins by Mixed-Solvent Molecular Dynamics Simulations. Journal of chemical information and modeling (2023)
Regina Rose Reimann, Martina Puzio, Antonella Rosati, Marc Emmenegger, Bernard L Schneider, Pamela Valdés, Danzhi Huang, Amedeo Caflisch, Adriano Aguzzi
Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity. Brain pathology (Zurich, Switzerland) (2022)
Francesco Nai, Raed Nachawati, František Zálešák, Xiang Wang, Yaozong Li, Amedeo Caflisch
Fragment Ligands of the m 6 A-RNA Reader YTHDF2. ACS medicinal chemistry letters 13 (9) (2022)
Andrea Dalle Vedove, Giulia Cazzanelli, Laurent Batiste, Jean-Rémy Marchand, Dimitrios Spiliotopoulos, Jessica Corsi, Vito Giuseppe D'Agostino, Amedeo Caflisch, Graziano Lolli
Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. ACS medicinal chemistry letters 13 (9) (2022)
Ilaria Salutari, Amedeo Caflisch
Dynamics of the Histone Acetyltransferase Lysine-Rich Loop in the Catalytic Core of the CREB-Binding Protein. Journal of chemical information and modeling 62 (4) (2022)
Maryam Haji Dehabadi, Amedeo Caflisch, Ioana M Ilie, Rohoullah Firouzi
Interactions of Curcumin's Degradation Products with the Aβ 42 Dimer: A Computational Study. The journal of physical chemistry. B 126 (39) (2022)
Yaozong Li, Rajiv Kumar Bedi, Lars Wiedmer, Xianqiang Sun, Danzhi Huang, Amedeo Caflisch
Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m6A) Recognition by the Reader Domain of YTHDC1. Journal of chemical theory and computation 17 (2) (2021)
Aymeric Dolbois, Rajiv K Bedi, Elena Bochenkova, Anna Müller, Elena V Moroz-Omori, Danzhi Huang, Amedeo Caflisch
1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors. Journal of medicinal chemistry 64 (17) (2021)
Andrea Dalle Vedove, Giulia Cazzanelli, Jessica Corsi, Maria Sedykh, Vito Giuseppe D'Agostino, Amedeo Caflisch, Graziano Lolli
Identification of a BAZ2A Bromodomain Hit Compound by Fragment Joining. ACS bio & med chem Au 1 (1) (2021)
Danilo Milardi, Ehud Gazit, Sheena E Radford, Yong Xu, Rodrigo U Gallardo, Amedeo Caflisch, Gunilla T Westermark, Per Westermark, Carmelo La Rosa, Ayyalusamy Ramamoorthy
Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes. Chemical reviews 121 (3) (2021)
Rajiv K Bedi, Danzhi Huang, Stefanie A Eberle, Lars Wiedmer, Pawel Śledź, Amedeo Caflisch
Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer. ChemMedChem 15 (9) (2020)
Yaozong Li, Rajiv K Bedi, Elena V Moroz-Omori, Amedeo Caflisch
Structural and Dynamic Insights into Redundant Function of YTHDF Proteins. Journal of chemical information and modeling 60 (12) (2020)
Amedeo Caflisch
Kinetic Control of Amyloidogenesis Calls for Unconventional Drugs To Fight Alzheimer's Disease. ACS chemical neuroscience 11 (2) (2020)
Kenneth Goossens, Berthold Wroblowski, Cassiano Langini, Herman W T van Vlijmen, Amedeo Caflisch, Hans De Winter
Assessment of the Fragment Docking Program SEED. Journal of chemical information and modeling 60 (10) (2020)
Jean-Rémy Marchand, Tim Knehans, Amedeo Caflisch, Andreas Vitalis
An ABSINTH-Based Protocol for Predicting Binding Affinities between Proteins and Small Molecules. Journal of chemical information and modeling 60 (10) (2020)
Marc Pretze, Christin Neuber, Elisa Kinski, Birgit Belter, Martin Köckerling, Amedeo Caflisch, Jörg Steinbach, Jens Pietzsch, Constantin Mamat
Synthesis, radiolabelling and initial biological characterisation of 18F-labelled xanthine derivatives for PET imaging of Eph receptors. Organic & biomolecular chemistry 18 (16) (2020)
Rajiv Kumar Bedi, Danzhi Huang, Lars Wiedmer, Yaozong Li, Aymeric Dolbois, Justyna Aleksandra Wojdyla, May Elizabeth Sharpe, Amedeo Caflisch, Paweł Śledź
Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. ACS chemical biology 15 (3) (2020)
Francesco Cocina, Andreas Vitalis, Amedeo Caflisch
Sapphire-Based Clustering. Journal of chemical theory and computation 16 (10) (2020)
Ioana M Ilie, Amedeo Caflisch
Simulation Studies of Amyloidogenic Polypeptides and Their Aggregates. Chemical reviews 119 (12) (2019)
Yaozong Li, Rajiv Kumar Bedi, Lars Wiedmer, Danzhi Huang, Paweł Śledź, Amedeo Caflisch
Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif. Journal of chemical theory and computation 15 (12) (2019)
Ilaria Salutari, Roland Martin, Amedeo Caflisch
The 3A6-TCR/superagonist/HLA-DR2a complex shows similar interface and reduced flexibility compared to the complex with self-peptide. Proteins 88 (1) (2019)
Marco Bacci, Amedeo Caflisch, Andreas Vitalis
On the removal of initial state bias from simulation data. The Journal of chemical physics 150 (10) (2019)
Lars Wiedmer, Stefanie Alexandra Eberle, Rajiv Kumar Bedi, Paweł Śledź, Amedeo Caflisch
A Reader-Based Assay for m6A Writers and Erasers. Analytical chemistry 91 (4) (2019)
Marco Bacci, Cassiano Langini, Jiří Vymětal, Amedeo Caflisch, Andreas Vitalis
Focused conformational sampling in proteins. The Journal of chemical physics 147 (19) (2018)
Ioana M Ilie, Amedeo Caflisch
Disorder at the Tips of a Disease-Relevant Aβ42 Amyloid Fibril: A Molecular Dynamics Study. The journal of physical chemistry. B 122 (49) (2018)
Carmen Esposito, L Wiedmer, Amedeo Caflisch
In Silico Identification of JMJD3 Demethylase Inhibitors. Journal of chemical information and modeling 58 (10) (2018)
Marco Bacci, Jiří Vymětal, Maja Mihajlovic, Amedeo Caflisch, Andreas Vitalis
Amyloid β Fibril Elongation by Monomers Involves Disorder at the Tip. Journal of chemical theory and computation 13 (10) (2017)
Antonio Peón, Adrián Robles, Beatriz Blanco, Marino Convertino, Paul Thompson, Alastair R Hawkins, Amedeo Caflisch, Concepción González-Bello
Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study. ChemMedChem 12 (18) (2017)
Cassiano Langini, Amedeo Caflisch, Andreas Vitalis
The ATAD2 bromodomain binds different acetylation marks on the histone H4 in similar fuzzy complexes. The Journal of biological chemistry 292 (40) (2017)
Jean-Rémy Marchand, Andrea Dalle Vedove, Graziano Lolli, Amedeo Caflisch
Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking. Journal of chemical information and modeling 57 (10) (2017)

Amedeo Caflisch.css-eqlu8i{font-size:small;padding-left:4px;} (A Caflisch)

Publication Activity (10 Years)

Top Topics

Top Venues

Amedeo Caflisch (A Caflisch)