Xi Cheng

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 40

Top Topics

Structural Basis

Acute Respiratory Distress Syndrome

Top Venues

Nature communications

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Xin-Heng He, Lifen Zhao, Yinping Tian, Rui Li, Qinyu Chu, Zhiyong Gu, Mingyue Zheng, Yusong Wang, Shaoning Li, Hualiang Jiang, Yi Jiang, Liuqing Wen, Dingyan Wang, Xi Cheng
Highly accurate carbohydrate-binding site prediction with DeepGlycanSite. Nature communications 15 (1) (2024)
Yu Zhang, Ye Tan, Zian Zhang, Xi Cheng, Jia Duan, Yi Li
Targeting Thyroid-Stimulating Hormone Receptor: A Perspective on Small-Molecule Modulators and Their Therapeutic Potential. Journal of medicinal chemistry (2024)
Guangda Yao, Yinping Tian, Wenjun Ke, Jie Fang, Shengzhou Ma, Tiehai Li, Xi Cheng, Bingqing Xia, Liuqing Wen, Zhaobing Gao
Direct Identification of Complex Glycans via a Highly Sensitive Engineered Nanopore. Journal of the American Chemical Society (2024)
Jianhui Zhou, Ning Wang, Mengxue Wang, Yuting Hu, Zhenwei Zhang, Zhiyong Gu, Jing Wang, Haowen Shou, Xi Cheng, Hong Liu, Yang Li, Yu Zhou
Discovery and Optimization of Tetrahydroisoquinoline Derivatives To Enhance Lysosome Biogenesis as Preclinical Candidates for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry 67 (11) (2024)
Tianhui Hao, Tian Mi, Qinyu Chu, Wenjing Ma, Xi Cheng, Yi Zang, Jia Li, Tiehai Li
Stereospecific Synthesis and Biological Evaluation of KRN7000 Analogues with Thio-modifications at the Acyl Moiety. ACS medicinal chemistry letters 15 (7) (2024)
Wonmuk Hwang, Steven L Austin, Arnaud Blondel, Eric D Boittier, Stefan Boresch, Matthias Buck, Joshua Buckner, Amedeo Caflisch, Hao-Ting Chang, Xi Cheng, Yeol Kyo Choi, Jhih-Wei Chu, Michael F Crowley, Qiang Cui, Ana Damjanovic, Yuqing Deng, Michael Devereux, Xinqiang Ding, Michael F Feig, Jiali Gao, David R Glowacki, James E Gonzales, Mehdi Bagerhi Hamaneh, Edward D Harder, Ryan L Hayes, Jing Huang, Yandong Huang, Phillip S Hudson, Wonpil Im, Shahidul M Islam, Wei Jiang, Michael R Jones, Silvan Käser, Fiona L Kearns, Nathan R Kern, Jeffery B Klauda, Themis Lazaridis, Jinhyuk Lee, Justin A Lemkul, Xiaorong Liu, Yun Lyna Luo, Alexander D MacKerell, Dan Thomas Major, Markus Meuwly, Kwangho Nam, Lennart Nilsson, Victor Ovchinnikov, Emanuele Paci, Soohyung Park, Richard W Pastor, Amanda R Pittman, Carol Beth Post, Samarjeet Prasad, Jingzhi Pu, John Z H Zhang, Thenmalarchelvi Rathinavelan, Daniel R Roe, Benoı T Roux, Christopher N Rowley, Jana Shen, Andrew C Simmonett, Alexander J Sodt, Kai Töpfer, Meenu Upadhyay, Arjan van der Vaart, Luis Itza Vazquez-Salazar, Richard M Venable, Luke C Warrensford, H Lee Woodcock, Yujin Wu, Charles L Brooks Iii, Bernard R Brooks, Martin Karplus
CHARMM at 45: Enhancements in Accessibility, Functionality, and Speed. The journal of physical chemistry. B (2024)
Tianhui Hao, Tian Mi, Qinyu Chu, Wenjing Ma, Xi Cheng, Yi Zang, Jia Li, Tiehai Li
Stereospecific Synthesis and Biological Evaluation of KRN7000 Analogues with Thio-modifications at the Acyl Moiety. ACS medicinal chemistry letters 15 (7) (2024)
Jianhui Zhou, Ning Wang, Mengxue Wang, Yuting Hu, Zhenwei Zhang, Zhiyong Gu, Jing Wang, Haowen Shou, Xi Cheng, Hong Liu, Yang Li, Yu Zhou
Discovery and Optimization of Tetrahydroisoquinoline Derivatives To Enhance Lysosome Biogenesis as Preclinical Candidates for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry (2024)
Xin-Heng He, Lifen Zhao, Yinping Tian, Rui Li, Qinyu Chu, Zhiyong Gu, Mingyue Zheng, Yusong Wang, Shaoning Li, Hualiang Jiang, Yi Jiang, Liuqing Wen, Dingyan Wang, Xi Cheng
Highly accurate carbohydrate-binding site prediction with DeepGlycanSite. Nature communications 15 (1) (2024)
Guangda Yao, Yinping Tian, Wenjun Ke, Jie Fang, Shengzhou Ma, Tiehai Li, Xi Cheng, Bingqing Xia, Liuqing Wen, Zhaobing Gao
Direct Identification of Complex Glycans via a Highly Sensitive Engineered Nanopore. Journal of the American Chemical Society 146 (19) (2024)
Lifen Zhao, Fangyu Wei, Xinheng He, Antao Dai, Dehua Yang, Hualiang Jiang, Liuqing Wen, Xi Cheng
Identification of a carbohydrate recognition motif of purinergic receptors. eLife 12 (2023)
Bingqing Xia, Jie Fang, Shengzhou Ma, Mengyao Ma, Guangda Yao, Tiehai Li, Xi Cheng, Liuqing Wen, Zhaobing Gao
Mapping the Acetylamino and Carboxyl Groups on Glycans by Engineered α-Hemolysin Nanopores. Journal of the American Chemical Society (2023)
Jia Duan, Peiyu Xu, Huibing Zhang, Xiaodong Luan, Jiaqi Yang, Xin-Heng He, Chunyou Mao, Dan-Dan Shen, Yujie Ji, Xi Cheng, Hualiang Jiang, Yi Jiang, Shu-Yang Zhang, Yan Zhang, H Eric Xu
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature communications 14 (1) (2023)
Heng Liu, Qing Zhang, Xin-Heng He, Mengting Jiang, Siwei Wang, Xiaoci Yan, Xi Cheng, Yang Liu, Fa-Jun Nan, H Eric Xu, Xin Xie, Wanchao Yin
Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84. Nature communications 14 (1) (2023)
Yujie Ji, Jia Duan, Qingning Yuan, Xin-Heng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Structural basis of peptide recognition and activation of endothelin receptors. Nature communications 14 (1) (2023)
Jia Duan, Peiyu Xu, Huibing Zhang, Xiaodong Luan, Jiaqi Yang, Xin-Heng He, Chunyou Mao, Dan-Dan Shen, Yujie Ji, Xi Cheng, Hualiang Jiang, Yi Jiang, Shu-Yang Zhang, Yan Zhang, H Eric Xu
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature communications 14 (1) (2023)
Jia Duan, Peiyu Xu, Huibing Zhang, Xiaodong Luan, Jiaqi Yang, Xin-Heng He, Chunyou Mao, Dan-Dan Shen, Yujie Ji, Xi Cheng, Hualiang Jiang, Yi Jiang, Shu-Yang Zhang, Yan Zhang, H Eric Xu
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature communications 14 (1) (2023)
Yujie Ji, Jia Duan, Qingning Yuan, Xin-Heng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Structural basis of peptide recognition and activation of endothelin receptors. Nature communications 14 (1) (2023)
Jia Duan, Peiyu Xu, Huibing Zhang, Xiaodong Luan, Jiaqi Yang, Xin-Heng He, Chunyou Mao, Dan-Dan Shen, Yujie Ji, Xi Cheng, Hualiang Jiang, Yi Jiang, Shu-Yang Zhang, Yan Zhang, H Eric Xu
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature communications 14 (1) (2023)
Jia Duan, Peiyu Xu, Huibing Zhang, Xiaodong Luan, Jiaqi Yang, Xin-Heng He, Chunyou Mao, Dan-Dan Shen, Yujie Ji, Xi Cheng, Hualiang Jiang, Yi Jiang, Shu-Yang Zhang, Yan Zhang, H Eric Xu
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature communications 14 (1) (2023)
Heng Liu, Qing Zhang, Xin-Heng He, Mengting Jiang, Siwei Wang, Xiaoci Yan, Xi Cheng, Yang Liu, Fa-Jun Nan, H Eric Xu, Xin Xie, Wanchao Yin
Author Correction: Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84. Nature communications 14 (1) (2023)
Yujie Ji, Jia Duan, Qingning Yuan, Xin-Heng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Structural basis of peptide recognition and activation of endothelin receptors. Nature communications 14 (1) (2023)
Jia Duan, Heng Liu, Fenghui Zhao, Qingning Yuan, Yujie Ji, Xiaoqing Cai, Xin-Heng He, Xinzhu Li, Junrui Li, Kai Wu, Tianyu Gao, Shengnan Zhu, Shi Lin, Ming-Wei Wang, Xi Cheng, Wanchao Yin, Yi Jiang, Dehua Yang, H Eric Xu
GPCR activation and GRK2 assembly by a biased intracellular agonist. Nature (2023)
Yue Wang, Weiyi Liu, Youwei Xu, Xin-Heng He, Qingning Yuan, Ping Luo, Wenjia Fan, Jingpeng Zhu, Xinyue Zhang, Xi Cheng, Yi Jiang, H Eric Xu, Youwen Zhuang
Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins. Nature chemical biology (2023)
Rui Li, Lin Chen, Xinheng He, Duanhua Cao, Zehong Zhang, Hualiang Jiang, Kaixian Cheng, Xi Cheng
Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein. Journal of chemical information and modeling (2023)
Hongmin Cai, Youwei Xu, Shimeng Guo, Xin-Heng He, Jun Sun, Xin Li, Changyao Li, Wanchao Yin, Xi Cheng, Hualiang Jiang, H Eric Xu, Xin Xie, Yi Jiang
Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell discovery 8 (1) (2022)
Na Wang, Xin-Heng He, Jing Zhao, Hualiang Jiang, Xi Cheng, Yu Xia, H Eric Xu, Yuanzheng He
Structural basis of leukotriene B4 receptor 1 activation. Nature communications 13 (1) (2022)
Jia Duan, Qiufeng Liu, Qingning Yuan, Yujie Ji, Shengnan Zhu, Yangxia Tan, Xin-Heng He, Youwei Xu, Jingjing Shi, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35. Cell discovery 8 (1) (2022)
Youwei Xu, Hongmin Cai, Chongzhao You, Xin-Heng He, Qingning Yuan, Hualiang Jiang, Xi Cheng, Yi Jiang, H Eric Xu
Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor. Cell research 32 (9) (2022)
Jia Duan, Qiufeng Liu, Qingning Yuan, Yujie Ji, Shengnan Zhu, Yangxia Tan, Xin-Heng He, Youwei Xu, Jingjing Shi, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35. Cell discovery 8 (1) (2022)
Peiyu Xu, Sijie Huang, Shimeng Guo, Ying Yun, Xi Cheng, Xin-Heng He, Pengjun Cai, Yuan Lan, Hu Zhou, Hualiang Jiang, Yi Jiang, Xin Xie, H Eric Xu
Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119. Nature structural & molecular biology 29 (9) (2022)
Jia Duan, Dan-Dan Shen, Tingting Zhao, Shimeng Guo, Xin-Heng He, Wanchao Yin, Peiyu Xu, Yujie Ji, Li-Nan Chen, Jinyu Liu, Huibing Zhang, Qiufeng Liu, Yi Shi, Xi Cheng, Hualiang Jiang, H Eric Xu, Yan Zhang, Xin Xie, Yi Jiang
Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors. Nature communications 13 (1) (2022)
Hongmin Cai, Youwei Xu, Shimeng Guo, Xin-Heng He, Jun Sun, Xin Li, Changyao Li, Wanchao Yin, Xi Cheng, Hualiang Jiang, H Eric Xu, Xin Xie, Yi Jiang
Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell discovery 8 (1) (2022)
Jia Duan, Peiyu Xu, Xiaodong Luan, Yujie Ji, Xin-Heng He, Ning Song, Qingning Yuan, Ye Jin, Xi Cheng, Hualiang Jiang, Jie Zheng, Shu-Yang Zhang, Yi Jiang, H Eric Xu
Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature 609 (7928) (2022)
Hongmin Cai, Youwei Xu, Shimeng Guo, Xin-Heng He, Jun Sun, Xin Li, Changyao Li, Wanchao Yin, Xi Cheng, Hualiang Jiang, H Eric Xu, Xin Xie, Yi Jiang
Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell discovery 8 (1) (2022)
Jia Duan, Qiufeng Liu, Qingning Yuan, Yujie Ji, Shengnan Zhu, Yangxia Tan, Xin-Heng He, Youwei Xu, Jingjing Shi, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35. Cell discovery 8 (1) (2022)
Jia Duan, Peiyu Xu, Xi Cheng, Chunyou Mao, Tristan Croll, Xin-Heng He, Jingjing Shi, Xiaodong Luan, Wanchao Yin, Erli You, Qiufeng Liu, Shu-Yang Zhang, Hualiang Jiang, Yan Zhang, Yi Jiang, H Eric Xu
Structures of full-length glycoprotein hormone receptor signalling complexes. Nature 598 (7882) (2021)
Youwen Zhuang, Brian E Krumm, Huibing Zhang, X Edward Zhou, Yue Wang, Xi-Ping Huang, Yongfeng Liu, Xi Cheng, Yi Jiang, Hualiang Jiang, Cheng Zhang, Wei Yi, Bryan L Roth, Yan Zhang, H Eric Xu
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor. Cell research 31 (5) (2021)
Bingqing Xia, Xurui Shen, Yang He, Xiaoyan Pan, Feng-Liang Liu, Yi Wang, Feipu Yang, Sui Fang, Yan Wu, Zilei Duan, Xiaoli Zuo, Zhuqing Xie, Xiangrui Jiang, Ling Xu, Hao Chi, Shuangqu Li, Qian Meng, Hu Zhou, Yubo Zhou, Xi Cheng, Xiaoming Xin, Lin Jin, Hai-Lin Zhang, Dan-Dan Yu, Ming-Hua Li, Xiao-Li Feng, Jie-Kai Chen, Hualiang Jiang, Gengfu Xiao, Yong-Tang Zheng, Lei-Ke Zhang, Jingshan Shen, Jia Li, Zhaobing Gao
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target. Cell research 31 (8) (2021)
Peiyu Xu, Sijie Huang, Huibing Zhang, Chunyou Mao, X Edward Zhou, Xi Cheng, Icaro A Simon, Dan-Dan Shen, Hsin-Yung Yen, Carol V Robinson, Kasper Harpsøe, Bo Svensson, Jia Guo, Hualiang Jiang, David E Gloriam, Karsten Melcher, Yi Jiang, Yan Zhang, H Eric Xu
Structural insights into the lipid and ligand regulation of serotonin receptors. Nature 592 (7854) (2021)