Sheena E Radford

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 92

Top Venues

Nature communications

Journal of the American Society for Mass Spectrometry

Nature

Journal of the American Chemical Society

University of Leeds

University of Birmingham (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Leeds Sep 01 2014

United Kingdom

Astbury Professor of Biophysics :: Astbury Centre for Structural Molecular Biology

University of Leeds Oct 01 2012

United Kingdom

Director :: Astbury Centre for Structural Molecular Biology

University of Leeds Oct 01 2000

United Kingdom

Professor of Structural Molecular Biology :: School of Biochemistry and Molecular Biology

University of Leeds Oct 01 2009 - Sep 30 2011

United Kingdom

Deputy Director :: Astbury Centre for Structural Molecular Biology

University of Leeds Oct 01 1998 - Sep 30 2000

United Kingdom

Reader in Structural Molecular Biology :: School of Biochemistry and Molecular Biology

University of Leeds Oct 01 1995 - Sep 30 1998

United Kingdom

Lecturer :: School of Biochemistry and Molecular Biology

Oxford Centre for Molecular Sciences Oct 01 1991 - Sep 30 1995

United Kingdom

Royal Society University Research Fellow :: Oxford Centre for Molecular Sciences

University of Oxford Sep 01 1988 - Sep 30 1991

United Kingdom

Postdoctoral researcher :: Inorganic Chemistry Laboratory, University of Oxford with Professor C.M. Dobson, FRS

University Of Oxford Jan 14 1988 - Aug 29 1988

United Kingdom

Postdoctoral researcher :: Dyson Perrins Lab, University of Oxford with Professor G. Lowe, FRS

Education History

University of Birmingham Sep 01 1981 - Jul 01 1984

United Kingdom

BSC :: Biochemistry

Publications

Dimitra Gialama, Devkee M Vadukul, Rebecca J Thrush, Sheena E Radford, Francesco Antonio Aprile
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region. Journal of medicinal chemistry 67 (12) (2024)
Samuel Berhanu, Sagardip Majumder, Thomas Müntener, James Whitehouse, Carolin Berner, Asim K Bera, Alex Kang, Binyong Liang, G Nasir Khan, Banumathi Sankaran, Lukas K Tamm, David J Brockwell, Sebastian Hiller, Sheena E Radford, Julien S Baker, Anastassia Andreevna Vorobieva
Sculpting conducting nanopore size and shape through de novo protein design. Science (New York, N.Y.) 385 (6706) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature 631 (8022) (2024)
Chalmers C Chau, Christopher M Maffeo, Aleksei Aksimentiev, Sheena E Radford, Eric W Hewitt, Paolo Actis
Single molecule delivery into living cells. Nature communications 15 (1) (2024)
Chalmers C Chau, Christopher M Maffeo, Aleksei Aksimentiev, Sheena E Radford, Eric W Hewitt, Paolo Actis
Single molecule delivery into living cells. Nature communications 15 (1) (2024)
Nikolaos N Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D'Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R Mackenzie, Rosa Rademakers, Neil A Ranson, Sheena E Radford, Frederic Rousseau, Joost Schymkowitz
Local structural preferences in shaping tau amyloid polymorphism. Nature communications 15 (1) (2024)
Nikolaos N Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D'Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R Mackenzie, Rosa Rademakers, Neil A Ranson, Sheena E Radford, Frederic Rousseau, Joost Schymkowitz
Local structural preferences in shaping tau amyloid polymorphism. Nature communications 15 (1) (2024)
Nikolaos N Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D'Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R Mackenzie, Rosa Rademakers, Neil A Ranson, Sheena E Radford, Frederic Rousseau, Joost Schymkowitz
Local structural preferences in shaping tau amyloid polymorphism. Nature communications 15 (1) (2024)
Bob Schiffrin, Joel A Crossley, Martin Walko, Jonathan M Machin, G Nasir Khan, Iain W Manfield, Andrew J Wilson, David J Brockwell, Tomas Fessl, Antonio N Calabrese, Sheena E Radford, Anastasia Zhuravleva
Dual client binding sites in the ATP-independent chaperone SurA. Nature communications 15 (1) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature 631 (8022) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Dimitra Gialama, Devkee M Vadukul, Rebecca J Thrush, Sheena E Radford, Francesco Antonio Aprile
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region. Journal of medicinal chemistry (2024)
Dimitra Gialama, Devkee M Vadukul, Rebecca J Thrush, Sheena E Radford, Francesco Antonio Aprile
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region. Journal of medicinal chemistry 67 (12) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Samuel Berhanu, Sagardip Majumder, Thomas Müntener, James Whitehouse, Carolin Berner, Asim K Bera, Alex Kang, Binyong Liang, G Nasir Khan, Banumathi Sankaran, Lukas K Tamm, David J Brockwell, Sebastian Hiller, Sheena E Radford, Julien S Baker, Anastassia Andreevna Vorobieva
Sculpting conducting nanopore size and shape through de novo protein design. Science (New York, N.Y.) 385 (6706) (2024)
Chalmers C Chau, Christopher M Maffeo, Aleksei Aksimentiev, Sheena E Radford, Eric W Hewitt, Paolo Actis
Single molecule delivery into living cells. Nature communications 15 (1) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature 631 (8022) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature (2024)
Dimitra Gialama, Devkee M Vadukul, Rebecca J Thrush, Sheena E Radford, Francesco Antonio Aprile
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region. Journal of medicinal chemistry 67 (12) (2024)
Katherine L Fenn, Jim E Horne, Joel A Crossley, Nils Böhringer, Romany J Horne, Till F Schäberle, Antonio N Calabrese, Sheena E Radford, Neil A Ranson
Outer membrane protein assembly mediated by BAM-SurA complexes. Nature communications 15 (1) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature (2024)
Dimitra Gialama, Devkee M Vadukul, Rebecca J Thrush, Sheena E Radford, Francesco Antonio Aprile
A Potent Sybody Selectively Inhibits α-Synuclein Amyloid Formation by Binding to the P1 Region. Journal of medicinal chemistry 67 (12) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature 631 (8022) (2024)
Nikolaos N Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D'Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R Mackenzie, Rosa Rademakers, Neil A Ranson, Sheena E Radford, Frederic Rousseau, Joost Schymkowitz
Local structural preferences in shaping tau amyloid polymorphism. Nature communications 15 (1) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Madeleine A G Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J O'Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H J Morrema, Mirjam Geibel, Randy J Read, Neil A Ranson, Sheena E Radford, Jeroen J M Hoozemans, René A W Frank
CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain. Nature (2024)
Nikolaos N Louros, Martin Wilkinson, Grigoria Tsaka, Meine Ramakers, Chiara Morelli, Teresa Garcia, Rodrigo Gallardo, Sam D'Haeyer, Vera Goossens, Dominique Audenaert, Dietmar Rudolf Thal, Ian R Mackenzie, Rosa Rademakers, Neil A Ranson, Sheena E Radford, Frederic Rousseau, Joost Schymkowitz
Local structural preferences in shaping tau amyloid polymorphism. Nature communications 15 (1) (2024)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry (2023)
Joel A Crossley, William John Allen, Daniel W Watkins, Tara Sabir, Sheena E Radford, Roman Tuma, Ian Collinson, Tomas Fessl
Dynamic coupling of fast channel gating with slow ATP-turnover underpins protein transport through the Sec translocon. The EMBO journal 43 (1) (2023)
Samuel F Haysom, Jonathan Machin, James M Whitehouse, Jim E Horne, Katherine Fenn, Yue Ma, Hassane El Mkami, Nils Böhringer, Till F Schäberle, Neil A Ranson, Sheena E Radford, Christos Pliotas
Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (34) (2023)
Jonathan M Machin, Antreas C Kalli, Neil A Ranson, Sheena E Radford
Protein-lipid charge interactions control the folding of outer membrane proteins into asymmetric membranes. Nature chemistry (2023)
Joel A Crossley, William John Allen, Daniel W Watkins, Tara Sabir, Sheena E Radford, Roman Tuma, Ian Collinson, Tomas Fessl
Dynamic coupling of fast channel gating with slow ATP-turnover underpins protein transport through the Sec translocon. The EMBO journal 43 (1) (2023)
Conny Leistner, Martin Wilkinson, Ailidh J O Burgess, Megan Lovatt, Stanley Goodbody, Yong Xu, Susan Deuchars, Sheena E Radford, Neil A Ranson, René A W Frank
The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain. Nature communications 14 (1) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Fabio Marcuccio, Dimitrios Soulias, Chalmers C C Chau, Sheena E Radford, Eric Hewitt, Paolo Actis, Martin Andrew Edwards
Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer-Electrolyte Nanopore. ACS nanoscience Au 3 (2) (2023)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Conny Leistner, Martin Wilkinson, Ailidh J O Burgess, Megan Lovatt, Stanley Goodbody, Yong Xu, Susan Deuchars, Sheena E Radford, Neil A Ranson, René A W Frank
The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain. Nature communications 14 (1) (2023)
Fabio Marcuccio, Dimitrios Soulias, Chalmers C C Chau, Sheena E Radford, Eric Hewitt, Paolo Actis, Martin Andrew Edwards
Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer-Electrolyte Nanopore. ACS nanoscience Au 3 (2) (2023)
Conny Leistner, Martin Wilkinson, Ailidh J O Burgess, Megan Lovatt, Stanley Goodbody, Yong Xu, Susan Deuchars, Sheena E Radford, Neil A Ranson, René A W Frank
The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain. Nature communications 14 (1) (2023)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Joel A Crossley, William John Allen, Daniel W Watkins, Tara Sabir, Sheena E Radford, Roman Tuma, Ian Collinson, Tomas Fessl
Dynamic coupling of fast channel gating with slow ATP-turnover underpins protein transport through the Sec translocon. The EMBO journal 43 (1) (2023)
Samuel F Haysom, Jonathan Machin, James M Whitehouse, Jim E Horne, Katherine Fenn, Yue Ma, Hassane El Mkami, Nils Böhringer, Till F Schäberle, Neil A Ranson, Sheena E Radford, Christos Pliotas
Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (34) (2023)
Fabio Marcuccio, Dimitrios Soulias, Chalmers C C Chau, Sheena E Radford, Eric Hewitt, Paolo Actis, Martin Andrew Edwards
Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer-Electrolyte Nanopore. ACS nanoscience Au 3 (2) (2023)
Martin Wilkinson, Rodrigo U Gallardo, Roberto Maya Martinez, Nicolas Guthertz, Masatomo So, Liam D Aubrey, Sheena E Radford, Neil A Ranson
Disease-relevant β 2 -microglobulin variants share a common amyloid fold. Nature communications 14 (1) (2023)
Fabio Marcuccio, Dimitrios Soulias, Chalmers C C Chau, Sheena E Radford, Eric Hewitt, Paolo Actis, Martin Andrew Edwards
Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer-Electrolyte Nanopore. ACS nanoscience Au 3 (2) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Chalmers C C Chau, Fabio Marcuccio, Dimitrios Soulias, Martin Andrew Edwards, Andrew Tuplin, Sheena E Radford, Eric Hewitt, Paolo Actis
Probing RNA Conformations Using a Polymer-Electrolyte Solid-State Nanopore. ACS nano (2022)
Bob Schiffrin, Jonathan M Machin, Theodoros K Karamanos, Anastasia Zhuravleva, David J Brockwell, Sheena E Radford, Antonio N Calabrese
Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding. Communications biology 5 (1) (2022)
Yong Xu, Roberto Maya-Martinez, Nicolas Guthertz, George R Heath, Iain W Manfield, Alexander L Breeze, Frank Sobott, Richard Foster, Sheena E Radford
Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly. Nature communications 13 (1) (2022)
Kevin Wu, Thomas C Minshull, Sheena E Radford, Antonio N Calabrese, James C A Bardwell
Trigger factor both holds and folds its client proteins. Nature communications 13 (1) (2022)
Sabine M Ulamec, Roberto Maya Martinez, Emily J Byrd, Katherine M Dewison, Yong Xu, Leon F Willis, Frank Sobott, George R Heath, Patricija van Oosten Hawle, Vladimir L Buchman, Sheena E Radford, David J Brockwell
Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein. Nature communications 13 (1) (2022)
Yong Xu, Roberto Maya-Martinez, Sheena E Radford
Controlling amyloid formation of intrinsically disordered proteins and peptides: slowing down or speeding up? Essays in biochemistry (2022)
Paul White, Samuel F Haysom, Matthew G Iadanza, Anna J Higgins, Jonathan M Machin, James M Whitehouse, Jim E Horne, Bob Schiffrin, Charlotte Carpenter-Platt, Antonio N Calabrese, Kelly M Storek, Steven T Rutherford, David J Brockwell, Neil A Ranson, Sheena E Radford
The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nature communications 12 (1) (2021)
Anastassia Andreevna Vorobieva, Paul White, Binyong Liang, Jim E Horne, Asim K Bera, Cameron M Chow, Stacey R Gerben, Sinduja K Marx, Alex Kang, Alyssa Q Stiving, Sophie R Harvey, Dagan C Marx, G Nasir Khan, Karen G Fleming, Vicki H Wysocki, David J Brockwell, Lukas K Tamm, Sheena E Radford, Julien S Baker
De novo design of transmembrane β barrels. Science (New York, N.Y.) 371 (6531) (2021)
Sheena E Radford, Theodoros K Karamanos
Finding the sweet spot for chaperone activity. Nature chemistry 13 (5) (2021)
Danilo Milardi, Ehud Gazit, Sheena E Radford, Yong Xu, Rodrigo U Gallardo, Amedeo Caflisch, Gunilla T Westermark, Per Westermark, Carmelo La Rosa, Ayyalusamy Ramamoorthy
Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes. Chemical reviews 121 (3) (2021)
Owen Cornwell, James R Ault, Nicholas J Bond, Sheena E Radford, Alison E Ashcroft
Investigation of D76N β2-Microglobulin Using Protein Footprinting and Structural Mass Spectrometry. Journal of the American Society for Mass Spectrometry 32 (7) (2021)
Ciaran P A Doherty, Sabine M Ulamec, Roberto Maya-Martinez, Sarah C Good, Jemma Makepeace, G Nasir Khan, Patricija van Oosten-Hawle, Sheena E Radford, David J Brockwell
A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function. Nature structural & molecular biology 27 (3) (2020)
Rodrigo U Gallardo, Matthew G Iadanza, Yong Xu, George R Heath, Richard Foster, Sheena E Radford, Neil A Ranson
Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nature structural & molecular biology 27 (11) (2020)
Bob Schiffrin, Sheena E Radford, David J Brockwell, Antonio N Calabrese
PyXlinkViewer: A flexible tool for visualization of protein chemical crosslinking data within the PyMOL molecular graphics system. Protein science : a publication of the Protein Society 29 (8) (2020)
Jessica S Ebo, Janet C Saunders, Paul W A Devine, Alice M Gordon, Amy S Warwick, Bob Schiffrin, Stacey E Chin, Elizabeth England, James D Button, Christopher Lloyd, Nicholas J Bond, Alison E Ashcroft, Sheena E Radford, David C Lowe, David J Brockwell
An in vivo platform to select and evolve aggregation-resistant proteins. Nature communications 11 (1) (2020)
Hugh I Smith, Nicolas Guthertz, Emma E Cawood, Roberto Maya-Martinez, Alexander L Breeze, Sheena E Radford
The role of the IT-state in D76N β2-microglobulin amyloid assembly: A crucial intermediate or an innocuous bystander? The Journal of biological chemistry 295 (35) (2020)
Jim E Horne, David J Brockwell, Sheena E Radford
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria. The Journal of biological chemistry 295 (30) (2020)
Emma E Cawood, Nicolas Guthertz, Jessica S Ebo, Theodoros K Karamanos, Sheena E Radford, Andrew J Wilson
Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules. Journal of the American Chemical Society 142 (49) (2020)
Antonio N Calabrese, Bob Schiffrin, Matthew Watson, Theodoros K Karamanos, Martin Walko, Julia R Humes, Jim E Horne, Paul White, Andrew J Wilson, Antreas C Kalli, Roman Tuma, Alison E Ashcroft, David J Brockwell, Sheena E Radford
Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients. Nature communications 11 (1) (2020)
Matthew G Iadanza, Bob Schiffrin, Paul White, Matthew A Watson, Jim E Horne, Anna J Higgins, Antonio N Calabrese, David J Brockwell, Roman Tuma, Antreas C Kalli, Sheena E Radford, Neil A Ranson
Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs. Communications biology 3 (1) (2020)
Raquel Rodríguez-Alonso, Juliette Létoquart, Van Son Nguyen, Gwennaelle Louis, Antonio N Calabrese, Bogdan I Iorga, Sheena E Radford, Seung-Hyun Cho, Han Remaut, Jean-François Collet
Structural insight into the formation of lipoprotein-β-barrel complexes. Nature chemical biology 16 (9) (2020)
Núria Benseny-Cases, Theodoros K Karamanos, Cody L Hoop, Jean Baum, Sheena E Radford
Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation. The Journal of biological chemistry 294 (24) (2019)
Theodoros K Karamanos, Matthew P Jackson, Antonio N Calabrese, Sophia C Goodchild, Emma E Cawood, Gary S Thompson, Arnout P Kalverda, Eric W Hewitt, Sheena E Radford
Structural mapping of oligomeric intermediates in an amyloid assembly pathway. eLife 8 (2019)
Martin Walko, Eric W Hewitt, Sheena E Radford, Andrew J Wilson
Design and synthesis of cysteine-specific labels for photo-crosslinking studies. RSC advances 9 (14) (2019)
Matthew G Iadanza, Matthew P Jackson, Eric W Hewitt, Neil A Ranson, Sheena E Radford
A new era for understanding amyloid structures and disease. Nature reviews. Molecular cell biology 19 (12) (2019)
Samuel J Bunce, Yiming Wang, Katie L Stewart, Alison E Ashcroft, Sheena E Radford, Carol K Hall, Andrew J Wilson
Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β40 (Aβ40) by the peptide fragment Aβ16-22. Science advances 5 (6) (2019)
Owen Cornwell, Nicholas J Bond, Sheena E Radford, Alison E Ashcroft
Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS. Analytical chemistry 91 (23) (2019)
Matthew G Iadanza, Robert Silvers, Joshua Boardman, Hugh I Smith, Theodoros K Karamanos, Galia T Debelouchina, Yongchao Su, Robert G Griffin, Neil A Ranson, Sheena E Radford
The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism. Nature communications 9 (1) (2018)
Esther M Martin, Matthew P Jackson, Martin Gamerdinger, Karina Gense, Theodoros K Karamonos, Julia R Humes, Elke Deuerling, Alison E Ashcroft, Sheena E Radford
Conformational flexibility within the nascent polypeptide-associated complex enables its interactions with structurally diverse client proteins. The Journal of biological chemistry 293 (22) (2018)
Tomas Fessl, Daniel W Watkins, Peter Oatley, William John Allen, Robin Adam Corey, Jim E Horne, Steve A Baldwin, Sheena E Radford, Ian Collinson, Roman Tuma
Dynamic action of the Sec machinery during initiation, protein translocation and termination. eLife 7 (2018)
Jim E Horne, Martin Walko, Antonio N Calabrese, Mark A Levenstein, David J Brockwell, Nikil Kapur, Andrew J Wilson, Sheena E Radford
Rapid Mapping of Protein Interactions Using Tag-Transfer Photocrosslinkers. Angewandte Chemie (International ed. in English) 57 (51) (2018)
Lydia M Young, Ling-Hsien Tu, Daniel P Raleigh, Alison E Ashcroft, Sheena E Radford
Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical science 8 (7) (2017)
Katie L Stewart, Sheena E Radford
Amyloid plaques beyond Aβ: a survey of the diverse modulators of amyloid aggregation. Biophysical reviews 9 (4) (2017)
William John Allen, Robin Adam Corey, Peter Oatley, Richard Barry Sessions, Steve A Baldwin, Sheena E Radford, Roman Tuma, Ian Collinson
Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation. eLife 5 (2016)
Matthew G Iadanza, Anna J Higgins, Bob Schiffrin, Antonio N Calabrese, David J Brockwell, Alison E Ashcroft, Sheena E Radford, Neil A Ranson
Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. Nature communications 7 (2016)

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Sheena E Radford