Ashley M Laughney

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 27

Top Venues

Nature cancer

Science (New York, N.Y.)

Science translational medicine

Nature medicine

Weill Cornell Medicine

Dartmouth College (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Weill Cornell Medicine Jul 01 2019

United States

Assistant Professor :: Physiology, Biophysics and Systems Biology

Memorial Sloan Kettering Cancer Center Jul 01 2014 - Jul 01 2019

United States

Research Associate :: Cancer Biology & Genetics

Harvard Medical School/Massachusetts General Hospital, Jun 30 2012 - Jun 30 2014

United States

Research Fellow

Education History

Dartmouth College Jun 30 2007 - Jun 30 2012

United States

PHD :: Thayer School of Engineering

University of Vermont Sep 01 2003 - Jun 01 2007

United States

BSC :: Physics

Publications

Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Melody DiBona, Yanyang Chen, Albert S Agustinus, Alice Mazzagatti, Mercedes A Duran, Matthew Deyell, Daniel Bronder, James H Hickling, Christy Hong, Lorenzo Scipioni, Giulia Tedeschi, Sara Martin, Jun Li, Aušrinė Ruzgaitė, Nadeem Riaz, Parin Shah, Edridge K D'Souza, D Zack Brodtman, Simone Sidoli, Bill Diplas, Manisha Jalan, Nancy Y Lee, Alban Ordureau, Benjamin Izar, Ashley M Laughney, Simon N Powell, Enrico Gratton, Stefano Santaguida, John Maciejowski, Peter Ly, Thomas M Jeitner, Samuel F Bakhoum
Micronuclear collapse from oxidative damage. Science (New York, N.Y.) 385 (6712) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter Karl Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David R Liu, Ashley M Laughney, Benjamin Izar
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer 5 (3) (2024)
Eric E Gardner, Ethan M Earlie, Kate Li, Jerin Thomas, Melissa J Hubisz, Benjamin D Stein, Chen Zhang, Lewis C Cantley, Ashley M Laughney, Harold Varmus
Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.) 383 (6683) (2024)
Priya Bhardwaj, Neil M Iyengar, Heba M Zahid, Katharine M Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E Dow, Sofya Oshchepkova, Dilip D Giri, Michael N Pollak, Xi Kathy Zhou, Benjamin D Hopkins, Ashley M Laughney, Melissa K Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A Spector, Lewis C Cantley, Kristy A Brown
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 . Science translational medicine 15 (684) (2023)
Priya Bhardwaj, Neil M Iyengar, Heba M Zahid, Katharine M Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E Dow, Sofya Oshchepkova, Dilip D Giri, Michael N Pollak, Xi Kathy Zhou, Benjamin D Hopkins, Ashley M Laughney, Melissa K Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A Spector, Lewis C Cantley, Kristy A Brown
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 . Science translational medicine 15 (684) (2023)
Jun Li, Melissa J Hubisz, Ethan M Earlie, Mercedes A Duran, Christy Hong, Austin A Varela, Emanuele Lettera, Matthew Deyell, Bernardo Tavora, Jonathan J Havel, Su M Phyu, Amit Dipak Amin, Karolina Budre, Erina Kamiya, Julie-Ann Cavallo, Christopher Garris, Simon N Powell, Jorge Sergio Reis-Filho, Hannah Wen, Sarah Bettigole, Atif J Khan, Benjamin Izar, Eileen E Parkes, Ashley M Laughney, Samuel F Bakhoum
Non-cell-autonomous cancer progression from chromosomal instability. Nature (2023)
Priya Bhardwaj, Neil M Iyengar, Heba M Zahid, Katharine M Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E Dow, Sofya Oshchepkova, Dilip D Giri, Michael N Pollak, Xi Kathy Zhou, Benjamin D Hopkins, Ashley M Laughney, Melissa K Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A Spector, Lewis C Cantley, Kristy A Brown
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 . Science translational medicine 15 (684) (2023)
Mathieu F Bakhoum, Jasmine H Francis, Albert S Agustinus, Ethan M Earlie, Melody DiBona, David H Abramson, Mercedes Duran, Ignas Masilionis, Elsa Molina, Alexander N Shoushtari, Michael H Goldbaum, Paul S Mischel, Samuel F Bakhoum, Ashley M Laughney
Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression. Nature communications 12 (1) (2021)
Matthew Deyell, Christopher S Garris, Ashley M Laughney
Cancer metastasis as a non-healing wound. British journal of cancer 124 (9) (2021)
Ashley M Laughney, Jing Hu, Nathaniel R Campbell, Samuel F Bakhoum, Manu Setty, Vincent-Philippe Lavallée, Yubin Xie, Ignas Masilionis, Ambrose J Carr, Sanjay Kottapalli, Viola Allaj, Marissa Mattar, Natasha Rekhtman, Joao B Xavier, Linas Mazutis, John T Poirier, Charles M Rudin, Dana Pe'er, Joan Massagué
Regenerative lineages and immune-mediated pruning in lung cancer metastasis. Nature medicine 26 (2) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ashley M Laughney