Bharath Srinivasan

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 20

Top Venues

Journal of medicinal chemistry

The FEBS journal

Medicinal research reviews

ChemMedChem

Instituto Gulbenkian de Ciencia

Jawaharlal Nehru Centre for Advanced Scientific Research (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Instituto Gulbenkian de Ciencia Feb 01 2017

Portugal

Postdoctoral Fellow :: NA

Georgia Institute of Technology Apr 25 2012 - Jan 31 2017

United States

Postdoctoral fellow :: Biology

Jawaharlal Nehru Centre for Advanced Scientific Research Aug 01 2005 - Apr 02 2012

India

Research Associate and PhD student :: Molecular Biology and Genetics Unit

Education History

Jawaharlal Nehru Centre for Advanced Scientific Research Aug 01 2005 - Apr 02 2012

India

PHD :: Molecular Biology and Genetics Unit

Bharathidasan University Jun 01 1998 - Apr 15 2001

India

BSC :: J J College of Arts and Science

Publications

Bharath Srinivasan
Advances in binding kinetics and mechanistic PK/PD modelling. British journal of pharmacology (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry 67 (16) (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry 67 (6) (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry 67 (16) (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry (2024)
Stephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, Sean Askin, Tony Cheung, Elisabetta Chiarparin, Muireann Coen, Iain T Collie, Ian L Dale, Claudia De Fusco, Keith Dillman, Laura Evans, Lyman J Feron, Alison J Foster, Michael Grondine, Vasudev Kantae, Gillian M Lamont, Scott Lamont, James T Lynch, Sten Nilsson Lill, Graeme R Robb, Jamal Saeh, Marianne Schimpl, James S Scott, James M Smith, Bharath Srinivasan, Sharon Tentarelli, Mercedes Vazquez-Chantada, David J Wagner, Jarrod J Walsh, David Watson, Beth Williamson
Development of a Series of Pyrrolopyridone MAT2A Inhibitors. Journal of medicinal chemistry (2024)
Bharath Srinivasan
Words of Advice: Teaching macromolecular crystallography. The FEBS journal (2023)
Bharath Srinivasan, Krzysztof Kuś, Alekos Athanasiadis
Thermodynamic analysis of Zα domain-nucleic acid interactions. The Biochemical journal 479 (16) (2022)
Bharath Srinivasan
A guide to enzyme kinetics in early drug discovery. The FEBS journal (2022)
Vasudev Kantae, Radoslaw Polanski, Hilary J Lewis, Afreen Haider, Derek Barratt, Bharath Srinivasan
Accelerating the Validation of Endogenous On-Target Engagement and In Cellulo Kinetic Assessment for Covalent Inhibitors of KRAS G12C in Early Drug Discovery. ACS chemical biology 17 (8) (2022)
Luisa Gabriel, Bharath Srinivasan, Krzysztof Kuś, João F Mata, Maria João Amorim, Lars E T Jansen, Alekos Athanasiadis
Enrichment of Zα domains at cytoplasmic stress granules is due to their innate ability to bind to nucleic acids. Journal of cell science 134 (10) (2021)
Puneet Khurana, Lisa McWilliams, Jonathan Wingfield, Derek Barratt, Bharath Srinivasan
A Novel High-Throughput FLIPR Tetra-Based Method for Capturing Highly Confluent Kinetic Data for Structure-Kinetic Relationship Guided Early Drug Discovery. SLAS discovery : advancing life sciences R & D 26 (5) (2021)
Bharath Srinivasan
A guide to the Michaelis-Menten equation: steady state and beyond. The FEBS journal (2021)
Bharath Srinivasan
Words of advice: teaching enzyme kinetics. The FEBS journal 288 (7) (2020)
Bharath Srinivasan, Vasudev Kantae, James Robinson
Resurrecting the phoenix: When an assay fails. Medicinal research reviews 40 (5) (2020)
Loic Carrique, Lionel Ballut, Arpit Shukla, Neelakshi Varma, Resmi Ravi, Sébastien Violot, Bharath Srinivasan, Umesh Tippagondanahalli Ganeshappa, Sonia Kulkarni, Hemalatha Balaram, Nushin Aghajari
Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nature communications 11 (1) (2020)
Bharath Srinivasan
Explicit Treatment of Non-Michaelis-Menten and Atypical Kinetics in Early Drug Discovery*. ChemMedChem 16 (6) (2020)
Bharath Srinivasan, Sam Tonddast-Navaei, Ambrish Roy, Hongyi Zhou, Jeffrey Skolnick
Chemical space of Escherichia coli dihydrofolate reductase inhibitors: New approaches for discovering novel drugs for old bugs. Medicinal research reviews 39 (2) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Bharath Srinivasan