Bernard Barlaam

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 15

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Molecular cancer therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry 67 (16) (2024)
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, David Benstead, Elaine Cadogan, Kan Chen, Calum R Cook, Nicola Colclough, Chao Deng, Stephen T Durant, Andrew Eatherton, Kristin Goldberg, Peter Johnström, Libin Liu, Zhaoqun Liu, J Willem M Nissink, Chengling Pang, Martin Pass, Graeme R Robb, Caroline Roberts, Magnus Schou, Oliver Steward, Andy Sykes, Yumei Yan, Baochang Zhai, Li Zheng
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390. Journal of medicinal chemistry 67 (4) (2024)
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, David Benstead, Elaine Cadogan, Kan Chen, Calum R Cook, Nicola Colclough, Chao Deng, Stephen T Durant, Andrew Eatherton, Kristin Goldberg, Peter Johnström, Libin Liu, Zhaoqun Liu, J Willem M Nissink, Chengling Pang, Martin Pass, Graeme R Robb, Caroline Roberts, Magnus Schou, Oliver Steward, Andy Sykes, Yumei Yan, Baochang Zhai, Li Zheng
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390. Journal of medicinal chemistry (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry 67 (16) (2024)
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, David Benstead, Elaine Cadogan, Kan Chen, Calum R Cook, Nicola Colclough, Chao Deng, Stephen T Durant, Andrew Eatherton, Kristin Goldberg, Peter Johnström, Libin Liu, Zhaoqun Liu, J Willem M Nissink, Chengling Pang, Martin Pass, Graeme R Robb, Caroline Roberts, Magnus Schou, Oliver Steward, Andy Sykes, Yumei Yan, Baochang Zhai, Li Zheng
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390. Journal of medicinal chemistry 67 (4) (2024)
James M Smith, Bernard Barlaam, David Beattie, Lauren Bradshaw, Ho Man Chan, Elisabetta Chiarparin, Olga Collingwood, Sophie L Cooke, Anna Cronin, Iain Cumming, Emma Dean, Judit É Debreczeni, Iván Del Barco Barrantes, Coura R Diene, Davide Gianni, Carine Guerot, Xiaoxiao Guo, Sinem Guven, Thomas G Hayhow, Ted Hong, Paul D Kemmitt, Gillian M Lamont, Scott Lamont, James T Lynch, Lisa McWilliams, Shaun Moore, Piotr Raubo, Graeme R Robb, James Robinson, James S Scott, Bharath Srinivasan, Oliver Steward, Christopher J Stubbs, Karl Syson, Lixiang Tan, Oliver Turner, Elizabeth Underwood, Jelena Urosevic, Mercedes Vazquez-Chantada, Amy L Whittaker, David M Wilson, Jon J Winter-Holt
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. Journal of medicinal chemistry (2024)
James S Scott, Darren Stead, Bernard Barlaam, Jason Breed, Rodrigo J Carbajo, Elisabetta Chiarparin, Natalie Cureton, Paul R J Davey, David I Fisher, Eric T Gangl, Tyler Grebe, Ryan D Greenwood, Sudhir Hande, Holia Hatoum-Mokdad, Samantha J Hughes, Thomas A Hunt, Tony Johnson, Stefan L Kavanagh, Teresa C M Klinowska, Carrie J B Larner, Mandy Lawson, Andrew S Lister, David Longmire, Stacey Marden, Thomas M McGuire, Caroline McMillan, Lindsay McMurray, Christopher J Morrow, J Willem M Nissink, Thomas A Moss, Daniel H O' Donovan, Radoslaw Polanski, Stephen Stokes, Kumar Thakur, Dawn Trueman, Caroline Truman, Michael J Tucker, Haixia Wang, Nicky Whalley, Dedong Wu, Ye Wu, Bin Yang, Wenzhan Yang
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. Journal of medicinal chemistry 66 (4) (2023)
James S Scott, Darren Stead, Bernard Barlaam, Jason Breed, Rodrigo J Carbajo, Elisabetta Chiarparin, Natalie Cureton, Paul R J Davey, David I Fisher, Eric T Gangl, Tyler Grebe, Ryan D Greenwood, Sudhir Hande, Holia Hatoum-Mokdad, Samantha J Hughes, Thomas A Hunt, Tony Johnson, Stefan L Kavanagh, Teresa C M Klinowska, Carrie J B Larner, Mandy Lawson, Andrew S Lister, David Longmire, Stacey Marden, Thomas M McGuire, Caroline McMillan, Lindsay McMurray, Christopher J Morrow, J Willem M Nissink, Thomas A Moss, Daniel H O' Donovan, Radoslaw Polanski, Stephen Stokes, Kumar Thakur, Dawn Trueman, Caroline Truman, Michael J Tucker, Haixia Wang, Nicky Whalley, Dedong Wu, Ye Wu, Bin Yang, Wenzhan Yang
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. Journal of medicinal chemistry 66 (4) (2023)
James S Scott, Darren Stead, Bernard Barlaam, Jason Breed, Rodrigo J Carbajo, Elisabetta Chiarparin, Natalie Cureton, Paul R J Davey, David I Fisher, Eric T Gangl, Tyler Grebe, Ryan D Greenwood, Sudhir Hande, Holia Hatoum-Mokdad, Samantha J Hughes, Thomas A Hunt, Tony Johnson, Stefan L Kavanagh, Teresa C M Klinowska, Carrie J B Larner, Mandy Lawson, Andrew S Lister, David Longmire, Stacey Marden, Thomas M McGuire, Caroline McMillan, Lindsay McMurray, Christopher J Morrow, J Willem M Nissink, Thomas A Moss, Daniel H O' Donovan, Radoslaw Polanski, Stephen Stokes, Kumar Thakur, Dawn Trueman, Caroline Truman, Michael J Tucker, Haixia Wang, Nicky Whalley, Dedong Wu, Ye Wu, Bin Yang, Wenzhan Yang
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. Journal of medicinal chemistry 66 (4) (2023)
James S Scott, Darren Stead, Bernard Barlaam, Jason Breed, Rodrigo J Carbajo, Elisabetta Chiarparin, Natalie Cureton, Paul R J Davey, David I Fisher, Eric T Gangl, Tyler Grebe, Ryan D Greenwood, Sudhir Hande, Holia Hatoum-Mokdad, Samantha J Hughes, Thomas A Hunt, Tony Johnson, Stefan L Kavanagh, Teresa C M Klinowska, Carrie J B Larner, Mandy Lawson, Andrew S Lister, David Longmire, Stacey Marden, Thomas M McGuire, Caroline McMillan, Lindsay McMurray, Christopher J Morrow, J Willem M Nissink, Thomas A Moss, Daniel H O' Donovan, Radoslaw Polanski, Stephen Stokes, Kumar Thakur, Dawn Trueman, Caroline Truman, Michael J Tucker, Haixia Wang, Nicky Whalley, Dedong Wu, Ye Wu, Bin Yang, Wenzhan Yang
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. Journal of medicinal chemistry (2023)
J Adam Hendricks, Nigel Beaton, Alexey Chernobrovkin, Eric Miele, Ghaith M Hamza, Piero Ricchiuto, Ronald C Tomlinson, Tomas Friman, Cassandra Borenstain, Bernard Barlaam, Sudhir Hande, Michelle L Lamb, Chris De Savi, Rick Davies, Martin Main, Joakim Hellner, Kristina Beeler, Yuehan Feng, Roland Bruderer, Lukas Reiter, Daniel Martinez Molina, M Paola Castaldi
Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics Methods. ACS chemical biology 17 (1) (2021)
Bernard Barlaam, Chris De Savi, Allan Dishington, Lisa Drew, Andrew D Ferguson, Douglas Ferguson, Chungang Gu, Sudhir Hande, Lorraine Hassall, Janet Hawkins, Alexander W Hird, Jane Holmes, Michelle L Lamb, Andrew S Lister, Thomas M McGuire, Jane E Moore, Nichole O'Connell, Anil Patel, Kurt G Pike, Ujjal Sarkar, Wenlin Shao, Darren Stead, Jeffrey G Varnes, Melissa M Vasbinder, Lei Wang, Liangwei Wu, Lin Xue, Bin Yang, Tieguang Yao
Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement. Journal of medicinal chemistry 64 (20) (2021)
Bernard Barlaam, Robert Casella, Justin Cidado, Calum Cook, Chris De Savi, Allan Dishington, Craig S Donald, Lisa Drew, Andrew D Ferguson, Douglas Ferguson, Steve Glossop, Tyler Grebe, Chungang Gu, Sudhir Hande, Janet Hawkins, Alexander W Hird, Jane Holmes, James Horstick, Yun Jiang, Michelle L Lamb, Thomas M McGuire, Jane E Moore, Nichole O'Connell, Andy Pike, Kurt G Pike, Theresa Proia, Bryan Roberts, Maryann San Martin, Ujjal Sarkar, Wenlin Shao, Darren Stead, Neil Sumner, Kumar Thakur, Melissa M Vasbinder, Jeffrey G Varnes, Jianyan Wang, Lei Wang, Dedong Wu, Liangwei Wu, Bin Yang, Tieguang Yao
Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies. Journal of medicinal chemistry 63 (24) (2020)
James S Scott, Thomas A Moss, Amber Balazs, Bernard Barlaam, Jason Breed, Rodrigo J Carbajo, Elisabetta Chiarparin, Paul R J Davey, Oona Delpuech, Stephen Fawell, David I Fisher, Sladjana Gagrica, Eric T Gangl, Tyler Grebe, Ryan D Greenwood, Sudhir Hande, Holia Hatoum-Mokdad, Kara Herlihy, Samantha Hughes, Thomas A Hunt, Hoan Huynh, Sophie L M Janbon, Tony Johnson, Stefan Kavanagh, Teresa Klinowska, Mandy Lawson, Andrew S Lister, Stacey Marden, Dermot F McGinnity, Christopher J Morrow, J Willem M Nissink, Daniel H O' Donovan, Bo Peng, Radoslaw Polanski, Darren S Stead, Stephen Stokes, Kumar Thakur, Scott R Throner, Michael J Tucker, Jeffrey Varnes, Haixia Wang, David M Wilson, Dedong Wu, Ye Wu, Bin Yang, Wenzhan Yang
Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist. Journal of medicinal chemistry 63 (23) (2020)
Lucy C Riches, Antonio G Trinidad, Adina M Hughes, Gemma N Jones, Andrew G Thomason, Paul Gavine, Andy Cui, Stephanie Ling, Jonathan Stott, Roger Clark, Samantha Peel, Pendeep Gill, Louise M Goodwin, Aaron Smith, Kurt G Pike, Bernard Barlaam, Martin Pass, Lenka Oplustil O'Connor, Graeme Smith, Elaine B Cadogan
Pharmacology of the ATM Inhibitor AZD0156: Potentiation of Irradiation and Olaparib Responses Preclinically. Molecular cancer therapeutics 19 (1) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Bernard Barlaam