Catherine L Tooke

ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 6

Top Venues

Angewandte Chemie (International ed. in English)

mBio

Antimicrobial agents and chemotherapy

RSC medicinal chemistry

Univeristy of Bristol

University of Bristol (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Univeristy of Bristol Nov 01 2019

United Kingdom

Postdoctoral Associate :: Cellular and Molecular Medicine

Education History

University of Bristol Sep 20 2015

United Kingdom

PHD :: Cellular and Molecular Medicine and Chemistry

University of Bristol Oct 01 2012 - Jun 20 2015

United Kingdom

BSC :: Cellular and Molecular Medicine

Publications

Catherine L Tooke, Philip Hinchliffe, Michael Beer, Kirill Zinovjev, Charlotte K Colenso, Christopher J Schofield, Adrian J Mulholland, James Spencer
Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase. Journal of the American Chemical Society (2023)
Philip Hinchliffe, Catherine L Tooke, Christopher R Bethel, Benlian Wang, Christopher Arthur, Kate J Heesom, Stuart Shapiro, Daniela M Schlatzer, Krisztina M Papp-Wallace, Robert A Bonomo, James Spencer
Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition. mBio 13 (3) (2022)
Catherine L Tooke, Philip Hinchliffe, Alen Krajnc, Adrian J Mulholland, Jürgen Brem, Christopher J Schofield, James Spencer
Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition. RSC medicinal chemistry 11 (4) (2020)
Catherine L Tooke, Philip Hinchliffe, Pauline A Lang, Adrian J Mulholland, Jürgen Brem, Christopher J Schofield, James Spencer
Molecular Basis of Class A β-Lactamase Inhibition by Relebactam. Antimicrobial agents and chemotherapy 63 (10) (2019)
Christopher T Lohans, H T Henry Chan, Tika R Malla, Kiran Kumar, Jos J A G Kamps, Darius J B McArdle, Emma van Groesen, Mariska de Munnik, Catherine L Tooke, James Spencer, Robert S Paton, Jürgen Brem, Christopher J Schofield
Non-Hydrolytic β-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine β-Lactamase Cysteine Variants. Angewandte Chemie (International ed. in English) 58 (7) (2019)
Christopher T Lohans, Emma van Groesen, Kiran Kumar, Catherine L Tooke, James Spencer, Robert S Paton, Jürgen Brem, Christopher J Schofield
A New Mechanism for β-Lactamases: Class D Enzymes Degrade 1β-Methyl Carbapenems through Lactone Formation. Angewandte Chemie (International ed. in English) 57 (5) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Catherine L Tooke