Pauline A Lang

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 12

Top Venues

Antimicrobial agents and chemotherapy

IUCrJ

Proceedings of the National Academy of Sciences of the United States of America

Nature chemistry

Johannes Gutenberg Universität Mainz (MSC)

This page only lists publications with an associated author ORCID identifier.

Education History

Johannes Gutenberg Universität Mainz

Germany

MSC :: Chemistry

Johannes Gutenberg Universität Mainz

Germany

BSC :: Chemistry

Publications

Mariska de Munnik, Pauline A Lang, Karina Calvopiña, Patrick Rabe, Jürgen Brem, Christopher J Schofield
Biochemical and crystallographic studies of L,D-transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate. Communications biology 7 (1) (2024)
Mariska de Munnik, Pauline A Lang, Francisco De Dios Anton, Mónica Cacho, Robert H Bates, Jürgen Brem, Beatriz Rodríguez Miquel, Christopher J Schofield
High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chemical science 14 (26) (2023)
Pauline A Lang, Ritu Raj, Anthony Tumber, Christopher T Lohans, Patrick Rabe, Carol V Robinson, Jürgen Brem, Christopher J Schofield
Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors. Proceedings of the National Academy of Sciences of the United States of America 119 (18) (2022)
Dave Lumen, Danielle J Vugts, Marion Chomet, Surachet Imlimthan, Mirkka P Sarparanta, Ricardo Vos, Maxime Schreurs, Mariska Verlaan, Pauline A Lang, Eero Hippeläinen, Wissam Beaino, Albert D Windhorst, Anu J Airaksinen
Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [ 89 Zr]Zr-DFO-PEG 5 -Tz. Bioconjugate chemistry 33 (5) (2022)
Pauline A Lang, Thomas M Leissing, Malcolm G P Page, Christopher J Schofield, Jürgen Brem
Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes. Antimicrobial agents and chemotherapy 65 (2) (2021)
Jürgen Brem, Tharindi D Panduwawala, Jon Ulf Hansen, Joanne Hewitt, Edgars Liepins, Pawel Donets, Laura Espina, Alistair J M Farley, Kirill Shubin, Gonzalo Gomez Campillos, Paula S Kiuru, Shifali Shishodia, Daniel Krahn, Robert K Leśniak, Juliane Schmidt Adrian, Karina Calvopiña, María-Carmen Turrientes, Madeline E Kavanagh, Dmitrijs Lubriks, Philip Hinchliffe, Gareth W Langley, Ali F Aboklaish, Anders Eneroth, Maria Backlund, Andrei G Baran, Elisabet I Nielsen, Michael Speake, Janis Kuka, John Robinson, Solveiga Grinberga, Lindsay Robinson, Michael A McDonough, Anna M Rydzik, Thomas M Leissing, Juan Carlos Jimenez-Castellanos, Matthew B Avison, Solange Da Silva Pinto, Andrew D Pannifer, Marina Martjuga, Emma Widlake, Martins Priede, Iva Hopkins Navratilova, Marek Gniadkowski, Anna Karin Belfrage, Peter Brandt, Jari T Yli-Kauhaluoma, Eric Bacque, Malcolm G P Page, Fredrik Björkling, Jonathan M Tyrrell, James Spencer, Pauline A Lang, Pawel Baranczewski, Rafael Cantón, Stuart P McElroy, Philip S Jones, Fernando Baquero, Edgars Suna, Angus Morrison, Timothy R Walsh, Christopher J Schofield
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nature chemistry 14 (1) (2021)
Patrick Rabe, Jos J A G Kamps, Kyle D Sutherlin, James D S Linyard, Pierre Aller, Cindy C Pham, Hiroki Makita, Ian J Clifton, Michael A McDonough, Thomas M Leissing, Denis Shutin, Pauline A Lang, Agata Butryn, Jürgen Brem, Sheraz Gul, Franklin D Fuller, In-Sik Kim, Mun Hon Cheah, Thomas Fransson, Asmit Bhowmick, Iris D Young, Lee J O'Riordan, Aaron S Brewster, Ilaria Pettinati, Margaret Doyle, Yasumasa Joti, Shigeki Owada, Kensure Tono, Alexander Batyuk, Mark S Hunter, Roberto Alonso Mori, Uwe Bergmann, Robin L Owen, Nicholas K Sauter, Timothy D W Claridge, Carol V Robinson, Vittal K Yachandra, Junko Yano, Jan F Kern, Allen M Orville, Christopher J Schofield
X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis. Science advances 7 (34) (2021)
Agata Butryn, Philipp S Simon, Pierre Aller, Philip Hinchliffe, Ramzi N Massad, Gabriel Leen, Catherine L Tooke, Isabel Bogacz, In-Sik Kim, Asmit Bhowmick, Aaron S Brewster, Nicholas E Devenish, Jürgen Brem, Jos J A G Kamps, Pauline A Lang, Patrick Rabe, Danny N Axford, John H Beale, Bradley Davy, Ali Ebrahim, Julien Orlans, Selina L S Storm, Tiankun Zhou, Shigeki Owada, Rie Tanaka, Kensuke Tono, Gwyndaf Evans, Robin L Owen, Frances A Houle, Nicholas K Sauter, Christopher J Schofield, James Spencer, Vittal K Yachandra, Junko Yano, Jan F Kern, Allen M Orville
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nature communications 12 (1) (2021)
Pauline A Lang, Anete Parkova, Thomas M Leissing, Karina Calvopiña, Ricky Cain, Alen Krajnc, Tharindi D Panduwawala, Jules Philippe, Colin W G Fishwick, Peteris Trapencieris, Malcolm G P Page, Christopher J Schofield, Jürgen Brem
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli. Biomolecules 10 (6) (2020)
Patrick Rabe, John H Beale, Agata Butryn, Pierre Aller, Anna Dirr, Pauline A Lang, Danny N Axford, Stephen B Carr, Thomas M Leissing, Michael A McDonough, Bradley Davy, Ali Ebrahim, Julien Orlans, Selina L S Storm, Allen M Orville, Christopher J Schofield, Robin L Owen
Anaerobic fixed-target serial crystallography. IUCrJ 7 (Pt 5) (2020)
Alen Krajnc, Jürgen Brem, Philip Hinchliffe, Karina Calvopiña, Tharindi D Panduwawala, Pauline A Lang, Jos J A G Kamps, Jonathan M Tyrrell, Emma Widlake, Benjamin G Saward, Timothy R Walsh, James Spencer, Christopher J Schofield
Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases. Journal of medicinal chemistry 62 (18) (2019)
Catherine L Tooke, Philip Hinchliffe, Pauline A Lang, Adrian J Mulholland, Jürgen Brem, Christopher J Schofield, James Spencer
Molecular Basis of Class A β-Lactamase Inhibition by Relebactam. Antimicrobial agents and chemotherapy 63 (10) (2019)

Pauline A Lang.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Pauline A Lang