Kresten Lindorff-Larsen

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 115

Top Venues

Nature communications

eLife

Journal of chemical theory and computation

Biochemistry

University of Copenhagen

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen Jul 01 2016

Denmark

Professor :: Department of Biology

University of Copenhagen Nov 01 2011 - Jul 01 2016

Denmark

Associate Professor :: Department of Biology

D E Shaw Research May 01 2007 - Oct 31 2011

United States

Senior scientist

University of Copenhagen Mar 01 2005 - Apr 30 2007

Denmark

Assistant Professor :: Department of Biochemistry

University of Copenhagen Oct 01 2004 - Feb 28 2005

Denmark

EMBO research fellow :: Department of Protein Chemistry

Maxygen ApS Mar 01 2001 - Aug 15 2001

Denmark

Protein chemist

Education History

University of Cambridge Sep 01 2001 - Oct 20 2004

United Kingdom

PHD :: Department of Chemistry and St. John's College

Publications

Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature 626 (8000) (2024)
Francesco Pesce, Anne Bremer, Giulio Tesei, Jesse B Hopkins, Christy R R Grace, Tanja Mittag, Kresten Lindorff-Larsen
Design of intrinsically disordered protein variants with diverse structural properties. Science advances 10 (35) (2024)
Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer Enøe Johansson, Thea K Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L Powell, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants. Nature communications 15 (1) (2024)
Johanna K S Tiemann, Magdalena Szczuka, Lisa Bouarroudj, Mohamed Oussaren, Steven Garcia, Rebecca J Howard, Lucie Delemotte, Erik Lindahl, Marc Baaden, Kresten Lindorff-Larsen, Matthieu Chavent, Pierre Poulain
MDverse, shedding light on the dark matter of molecular dynamics simulations. eLife 12 (2024)
Frederik Gouliaev, Nicolas Jonsson, Sarah K Gersing, Michael Lisby, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Destabilization and Degradation of a Disease-Linked PGM1 Protein Variant. Biochemistry (2024)
Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature 626 (8000) (2024)
Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature (2024)
Samuel E Hoff, F Emil Thomasen, Kresten Lindorff-Larsen, Massimiliano Bonomi
Accurate model and ensemble refinement using cryo-electron microscopy maps and Bayesian inference. PLoS computational biology 20 (7) (2024)
Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer Enøe Johansson, Thea K Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L Powell, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants. Nature communications 15 (1) (2024)
Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature (2024)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries. Communications biology 7 (1) (2024)
F Emil Thomasen, Tórur Skaalum, Ashutosh Kumar, Sriraksha Srinivasan, Stefano Vanni, Kresten Lindorff-Larsen
Rescaling protein-protein interactions improves Martini 3 for flexible proteins in solution. Nature communications 15 (1) (2024)
Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature 626 (8000) (2024)
Frederik Gouliaev, Nicolas Jonsson, Sarah K Gersing, Michael Lisby, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Destabilization and Degradation of a Disease-Linked PGM1 Protein Variant. Biochemistry 63 (11) (2024)
Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature 626 (8000) (2024)
Samuel E Hoff, F Emil Thomasen, Kresten Lindorff-Larsen, Massimiliano Bonomi
Accurate model and ensemble refinement using cryo-electron microscopy maps and Bayesian inference. PLoS computational biology 20 (7) (2024)
Samuel E Hoff, F Emil Thomasen, Kresten Lindorff-Larsen, Massimiliano Bonomi
Accurate model and ensemble refinement using cryo-electron microscopy maps and Bayesian inference. PLoS computational biology 20 (7) (2024)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries. Communications biology 7 (1) (2024)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries. Communications biology 7 (1) (2024)
Frederik Gouliaev, Nicolas Jonsson, Sarah K Gersing, Michael Lisby, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Destabilization and Degradation of a Disease-Linked PGM1 Protein Variant. Biochemistry 63 (11) (2024)
F Emil Thomasen, Tórur Skaalum, Ashutosh Kumar, Sriraksha Srinivasan, Stefano Vanni, Kresten Lindorff-Larsen
Rescaling protein-protein interactions improves Martini 3 for flexible proteins in solution. Nature communications 15 (1) (2024)
Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer Enøe Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L Powell, Magnus K N Have, Vibe H Oestergaard, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
A mutational atlas for Parkin proteostasis. Nature communications 15 (1) (2024)
F Emil Thomasen, Tórur Skaalum, Ashutosh Kumar, Sriraksha Srinivasan, Stefano Vanni, Kresten Lindorff-Larsen
Rescaling protein-protein interactions improves Martini 3 for flexible proteins in solution. Nature communications 15 (1) (2024)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries. Communications biology 7 (1) (2024)
Samuel E Hoff, F Emil Thomasen, Kresten Lindorff-Larsen, Massimiliano Bonomi
Accurate model and ensemble refinement using cryo-electron microscopy maps and Bayesian inference. PLoS computational biology 20 (7) (2024)
Francesco Pesce, Anne Bremer, Giulio Tesei, Jesse B Hopkins, Christy R R Grace, Tanja Mittag, Kresten Lindorff-Larsen
Design of intrinsically disordered protein variants with diverse structural properties. Science advances 10 (35) (2024)
Giulio Tesei, Anna Ida Trolle, Nicolas Jonsson, Johannes Betz, Frederik E Knudsen, Francesco Pesce, Kristoffer E Johansson, Kresten Lindorff-Larsen
Conformational ensembles of the human intrinsically disordered proteome. Nature (2024)
Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer Enøe Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L Powell, Magnus K N Have, Vibe H Oestergaard, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
A mutational atlas for Parkin proteostasis. Nature communications 15 (1) (2024)
Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer Enøe Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L Powell, Magnus K N Have, Vibe H Oestergaard, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
A mutational atlas for Parkin proteostasis. Nature communications 15 (1) (2024)
Francesco Pesce, Anne Bremer, Giulio Tesei, Jesse B Hopkins, Christy R R Grace, Tanja Mittag, Kresten Lindorff-Larsen
Design of intrinsically disordered protein variants with diverse structural properties. Science advances 10 (35) (2024)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: a Python package for FRET efficiency predictions using rotamer libraries. Communications biology 7 (1) (2024)
Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer Enøe Johansson, Thea K Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L Powell, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants. Nature communications 15 (1) (2024)
Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer Enøe Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L Powell, Magnus K N Have, Vibe H Oestergaard, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
A mutational atlas for Parkin proteostasis. Nature communications 15 (1) (2024)
Giulio Tesei, Kresten Lindorff-Larsen
Improved predictions of phase behaviour of intrinsically disordered proteins by tuning the interaction range. Open research Europe 2 (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
Sarah K Gersing, Thea K Schulze, Matteo Cagiada, Amelie Stein, Frederick P Roth, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Characterizing glucokinase variant mechanisms using a multiplexed abundance assay. bioRxiv : the preprint server for biology (2023)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: A Python package for FRET efficiency predictions using rotamer libraries. bioRxiv : the preprint server for biology (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
Raul Araya-Secchi, Katrine Bugge, Pernille Seiffert, Amalie Petry, Gitte W Haxholm, Kresten Lindorff-Larsen, Stine Helene Falsig Pedersen, Lise Arleth, Birthe B Kragelund
The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate. eLife 12 (2023)
Andreas Oxenfarth, Felix Kümmerer, Sandro Bottaro, Robbin Schnieders, György Pinter, Hendrik R A Jonker, Boris Fürtig, Christian Richter, Martin Blackledge, Kresten Lindorff-Larsen, Harald Schwalbe
Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop. Journal of the American Chemical Society (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
Daniel Flores-Téllez, Mathias Due Tankmar, Sören von Bülow, Junyu Chen, Kresten Lindorff-Larsen, Peter Brodersen, Laura Arribas-Hernández
Insights into the conservation and diversification of the molecular functions of YTHDF proteins. PLoS genetics 19 (10) (2023)
Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Rare Catechol- O -methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets. Biochemistry (2023)
Francesco Pesce, Kresten Lindorff-Larsen
Combining Experiments and Simulations to Examine the Temperature-Dependent Behavior of a Disordered Protein. The journal of physical chemistry. B (2023)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: A Python package for FRET efficiency predictions using rotamer libraries. bioRxiv : the preprint server for biology (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
Daniele Montepietra, Giulio Tesei, João Miguel Martins, Micha B A Kunze, Robert B Best, Kresten Lindorff-Larsen
FRETpredict: A Python package for FRET efficiency predictions using rotamer libraries. bioRxiv : the preprint server for biology (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
Felix Kümmerer, Simone Orioli, Kresten Lindorff-Larsen
Fitting Force Field Parameters to NMR Relaxation Data. Journal of chemical theory and computation (2023)
Mireya Martínez-Pérez, Frederic Aparicio, Laura Arribas-Hernández, Mathias Due Tankmar, Sarah Rennie, Sören von Bülow, Kresten Lindorff-Larsen, Peter Brodersen, Vicente Pallas
Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus. The EMBO journal (2023)
F Emil Thomasen, Francesco Pesce, Mette Ahrensback Roesgaard, Giulio Tesei, Kresten Lindorff-Larsen
Correction to "Improving Martini 3 for Disordered and Multidomain Proteins". Journal of chemical theory and computation 19 (10) (2023)
Johanna K S Tiemann, Magdalena Szczuka, Lisa Bouarroudj, Mohamed Oussaren, Steven Garcia, Rebecca J Howard, Lucie Delemotte, Erik Lindahl, Marc Baaden, Kresten Lindorff-Larsen, Matthieu Chavent, Pierre Poulain
MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations. bioRxiv : the preprint server for biology (2023)
Thibaud Dieudonné, Felix Kümmerer, Michelle Juknaviciute Laursen, Charlott Stock, Rasmus Kock Flygaard, Syma Khalid, Guillaume Lenoir, Joseph Anthony Lyons, Kresten Lindorff-Larsen, Poul Nissen
Activation and substrate specificity of the human P4-ATPase ATP8B1. Nature communications 14 (1) (2023)
F Emil Thomasen, Matthew J Cuneo, Tanja Mittag, Kresten Lindorff-Larsen
Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations. eLife 12 (2023)
Johanna K S Tiemann, Magdalena Szczuka, Lisa Bouarroudj, Mohamed Oussaren, Steven Garcia, Rebecca J Howard, Lucie Delemotte, Erik Lindahl, Marc Baaden, Kresten Lindorff-Larsen, Matthieu Chavent, Pierre Poulain
MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations. bioRxiv : the preprint server for biology (2023)
Francesco Pesce, Anne Bremer, Giulio Tesei, Jesse B Hopkins, Christy R R Grace, Tanja Mittag, Kresten Lindorff-Larsen
Design of intrinsically disordered protein variants with diverse structural properties. bioRxiv : the preprint server for biology (2023)
Lasse M Blaabjerg, Maher M Kassem, Lydia L Good, Nicolas Jonsson, Matteo Cagiada, Kristoffer E Johansson, Wouter Boomsma, Amelie Stein, Kresten Lindorff-Larsen
Rapid protein stability prediction using deep learning representations. eLife 12 (2023)
F Emil Thomasen, Francesco Pesce, Mette Ahrensback Roesgaard, Giulio Tesei, Kresten Lindorff-Larsen
Correction to "Improving Martini 3 for Disordered and Multidomain Proteins". Journal of chemical theory and computation (2023)
Matteo Cagiada, Sandro Bottaro, Søren Lindemose, Signe M Schenstrøm, Amelie Stein, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen
Discovering functionally important sites in proteins. Nature communications 14 (1) (2023)
Amanda B Abildgaard, Sofie V Nielsen, Inge Bernstein, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Lynch syndrome, molecular mechanisms and variant classification. British journal of cancer (2022)
Yulian Gavrilov, Felix Kümmerer, Simone Orioli, Andreas Prestel, Kresten Lindorff-Larsen, Kaare Teilum
Double Mutant of Chymotrypsin Inhibitor 2 Stabilized through Increased Conformational Entropy. Biochemistry 61 (3) (2022)
F Emil Thomasen, Francesco Pesce, Mette Ahrensback Roesgaard, Giulio Tesei, Kresten Lindorff-Larsen
Improving Martini 3 for Disordered and Multidomain Proteins. Journal of chemical theory and computation 18 (4) (2022)
Nicolai Tidemand Johansen, Marta Bonaccorsi, Tone Bengtsen, Andreas Haahr Larsen, Frederik Grønbæk Tidemand, Martin Cramer Pedersen, Pie Huda, Jens Berndtsson, Tamim A Darwish, Nageshewar Rao Yepuri, Anne Martel, Thomas Günther Pomorski, Andrea Bertarello, Mark S P Sansom, Mikaela Rapp, Ramon Crehuet, Tobias Schubeis, Kresten Lindorff-Larsen, Guido Pintacuda, Lise Arleth
Mg 2+ -dependent conformational equilibria in CorA and an integrated view on transport regulation. eLife 11 (2022)
Silvia Gaggero, Jonathan Martínez-Fábregas, Adeline Cozzani, Paul K Fyfe, Malo Leprohon, Jie Yang, F Emil Thomasen, Hauke Winkelmann, Romain Magnez, Alberto G Conti, Stephan Wilmes, Elizabeth Pohler, Manuel van Gijsel Bonnello, Xavier Thuru, Bruno Quesnel, Fabrice Soncin, Jacob Piehler, Kresten Lindorff-Larsen, Rahul Roychoudhuri, Ignacio Moraga, Suman Mitra
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein. Science immunology 7 (78) (2022)
Johanna Maarit Koivisto, Nina Rødtness Poulsen, Benedikte Stoklund Larsen, M G M Weibull, Amelie Stein, Fabio Doro, Jakob Rahr Winther, Kresten Lindorff-Larsen, Martin Willemoës
Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system. The Biochemical journal 479 (4) (2022)
Mehmet Akdel, Douglas E V Pires, Eduard Porta Pardo, Jürgen Jänes, Arthur O Zalevsky, Bálint Mészáros, Patrick Bryant, Lydia L Good, Roman A Laskowski, Gabriele Pozzati, Aditi Shenoy, Wensi Zhu, Petras Kundrotas, Victoria Ruiz Serra, Carlos Henrique Miranda, Alistair S Dunham, David Francis Burke, Neera Borkakoti, Sameer Velankar, Adam Frost, Jérôme Basquin, Kresten Lindorff-Larsen, Alex Bateman, Andrey V Kajava, Alfonso Valencia, Sergey Ovchinnikov, Janani Durairaj, David Benjamin Ascher, Janet M Thornton, Norman E Davey, Amelie Stein, Arne Elofsson, Tristan I Croll, Pedro Beltrao
A structural biology community assessment of AlphaFold2 applications. Nature structural & molecular biology 29 (11) (2022)
Kristiane R Torgeson, Michael W Clarkson, Daniele Granata, Kresten Lindorff-Larsen, Rebecca Page, Wolfgang Peti
Conserved conformational dynamics determine enzyme activity. Science advances 8 (31) (2022)
Caroline Neumann, Lena Lindtoft Rosenbaek, Rasmus Kock Flygaard, Michael Habeck, Jesper Lykkegaard Karlsen, Yong Wang, Kresten Lindorff-Larsen, Hans Henrik Gad, Rune Hartmann, Joseph Anthony Lyons, Robert A Fenton, Poul Nissen
Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity. The EMBO journal 41 (23) (2022)
Bayan Mashahreh, Shir Armony, Kristoffer Enøe Johansson, Alon Chappleboim, Nir Friedman, Richard G Gardner, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen, Tommer Ravid
Conserved degronome features governing quality control associated proteolysis. Nature communications 13 (1) (2022)
F Emil Thomasen, Kresten Lindorff-Larsen
Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins. Biochemical Society transactions 50 (1) (2022)
Esben B Svenningsen, Rasmus N Ottosen, Katrine H Jørgensen, Marija Nisavic, Camilla K Larsen, Bente K Hansen, Yong Wang, Kresten Lindorff-Larsen, Thomas Tørring, Stephan M Hacker, Johan Palmfeldt, Thomas B Poulsen
The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21. RSC chemical biology 3 (10) (2022)
Mette Ahrensback Roesgaard, Jeppe E Lundsgaard, Estella A Newcombe, Nina L Jacobsen, Francesco Pesce, Emil E Tranchant, Søren Lindemose, Andreas Prestel, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen, Birthe B Kragelund
Deciphering the Alphabet of Disorder-Glu and Asp Act Differently on Local but Not Global Properties. Biomolecules 12 (10) (2022)
Ariane Zutz, Louise Hamborg, Lasse Ebdrup Pedersen, Maher M Kassem, Elena Papaleo, Anna Koza, Markus J Herrgård, Sheila Ingemann Jensen, Kaare Teilum, Kresten Lindorff-Larsen, Alex Toftgaard Nielsen
A dual-reporter system for investigating and optimizing protein translation and folding in E. coli. Nature communications 12 (1) (2021)
Louise Hamborg, Daniele Granata, Johan G Olsen, Jennifer Virginia Roche, Lasse Ebdrup Pedersen, Alex Toftgaard Nielsen, Kresten Lindorff-Larsen, Kaare Teilum
Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Communications biology 4 (1) (2021)
Kaituo Wang, Robert Dagil, Thomas Lavstsen, Sandeep K Misra, Charlotte B Spliid, Yong Wang, Tobias Gustavsson, Daniel R Sandoval, Elena Ethel Vidal-Calvo, Swati Choudhary, Mette Ø Agerbaek, Kresten Lindorff-Larsen, Morten Agertoug Nielsen, Thor G Theander, Joshua S Sharp, Thomas Mandel Clausen, Pontus Emanuel Gourdon, Ali Salanti
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nature communications 12 (1) (2021)
Frederikke Isa Marin, Kristoffer Enøe Johansson, Charlotte O'Shea, Kresten Lindorff-Larsen, Jakob Rahr Winther
Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold. The journal of physical chemistry. B 125 (40) (2021)
Julia Koehler Leman, Sergey Lyskov, Steven M Lewis, Jared Adolf-Bryfogle, Rebecca F Alford, Kyle A Barlow, Ziv Ben-Aharon, Daniel P Farrell, Jason S Fell, William A Hansen, Ameya Harmalkar, Jeliazko R Jeliazkov, Georg Kuenze, Justyna Dorota Kryś, Ajasja Ljubetič, Amanda L Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L Nance, Phuong T Nguyen, Shane Ó Conchúir, Shourya S Roy Burman, Rituparna Samanta, Shannon T Smith, Frank Teets, Johanna K S Tiemann, Andrew Watkins, Hope Woods, Brahm J Yachnin, Christopher D Bahl, Chris Bailey-Kellogg, Julien S Baker, Rachel J Hagey, Frank DiMaio, Sagar D Khare, Tanja Kortemme, Jason W Labonte, Kresten Lindorff-Larsen, Jens Meiler, William R Schief, Ora Schueler-Furman, Justin B Siegel, Amelie Stein, Vladimir Yarov-Yarovoy, Brian Kuhlman, Andrew Leaver-Fay, Dominik Gront, Jeffrey J Gray, Richard A Bonneau
Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks. Nature communications 12 (1) (2021)
Sarah K Gersing, Yong Wang, Martin Grønbæk-Thygesen, Caroline Kampmeyer, Lene Clausen, Martin Willemoës, Claes Andréasson, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Mapping the degradation pathway of a disease-linked aspartoacylase variant. PLoS genetics 17 (4) (2021)
Sofie V Nielsen, Rasmus Hartmann-Petersen, Amelie Stein, Kresten Lindorff-Larsen
Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition. PLoS genetics 17 (4) (2021)
Sandro Bottaro, Giovanni Bussi, Kresten Lindorff-Larsen
Conformational Ensembles of Noncoding Elements in the SARS-CoV-2 Genome from Molecular Dynamics Simulations. Journal of the American Chemical Society 143 (22) (2021)
Stefan Hervø-Hansen, Casper Højgaard, Kristoffer Enøe Johansson, Yong Wang, Khadija Wahni, David Young, Joris Messens, Kaare Teilum, Kresten Lindorff-Larsen, Jakob Rahr Winther
Charge Interactions in a Highly Charge-Depleted Protein. Journal of the American Chemical Society 143 (6) (2021)
Stephanie Jephthah, Francesco Pesce, Kresten Lindorff-Larsen, Marie Skepö
Force Field Effects in Simulations of Flexible Peptides with Varying Polyproline II Propensity. Journal of chemical theory and computation 17 (10) (2021)
Estella A Newcombe, Catarina B Fernandes, Jeppe E Lundsgaard, Inna Brakti, Kresten Lindorff-Larsen, Annette Eva Langkilde, Karen Skriver, Birthe B Kragelund
Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins. Biomolecules 11 (8) (2021)
Matteo Cagiada, Kristoffer E Johansson, Audrone Valanciute, Sofie V Nielsen, Rasmus Hartmann-Petersen, Jun J Yang, Douglas M Fowler, Amelie Stein, Kresten Lindorff-Larsen
Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance. Molecular biology and evolution 38 (8) (2021)
Giulio Tesei, João Miguel Martins, Micha B A Kunze, Yong Wang, Ramon Crehuet, Kresten Lindorff-Larsen
DEER-PREdict: Software for efficient calculation of spin-labeling EPR and NMR data from conformational ensembles. PLoS computational biology 17 (1) (2021)
Noah Kassem, Raul Araya-Secchi, Katrine Bugge, Abigail Barclay, Helena Steinocher, Adree Khondker, Yong Wang, Aneta J Lenard, Jochen Bürck, Cagla Sahin, Anne S Ulrich, Michael Landreh, Martin Cramer Pedersen, Maikel C Rheinstädter, Per Amstrup Pedersen, Kresten Lindorff-Larsen, Lise Arleth, Birthe B Kragelund
Order and disorder-An integrative structure of the full-length human growth hormone receptor. Science advances 7 (27) (2021)
Dennis V Pedersen, Martin Nors Pedersen, Sofia Mm Mazarakis, Yong Wang, Kresten Lindorff-Larsen, Lise Arleth, Gregers Rom Andersen
Properdin oligomers adopt rigid extended conformations supporting function. eLife 10 (2021)
Felix Kümmerer, Simone Orioli, David Harding-Larsen, Falk Hoffmann, Yulian Gavrilov, Kaare Teilum, Kresten Lindorff-Larsen
Fitting Side-Chain NMR Relaxation Data Using Molecular Simulations. Journal of chemical theory and computation 17 (8) (2021)
Giulio Tesei, Thea K Schulze, Ramon Crehuet, Kresten Lindorff-Larsen
Accurate model of liquid-liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties. Proceedings of the National Academy of Sciences of the United States of America 118 (44) (2021)
Amanda B Abildgaard, Sarah K Gersing, Sven Larsen-Ledet, Sofie V Nielsen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome. Biomolecules 10 (8) (2020)
Brian K Shoichet, Kresten Lindorff-Larsen, Massimiliano Bonomi
What Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data? Journal of chemical information and modeling 60 (5) (2020)
Iva Sučec, Yong Wang, Ons Dakhlaoui, Katharina Weinhäupl, Tobias Jores, Doriane Costa, Audrey Hessel, Martha E Brennich, Doron Rapaport, Kresten Lindorff-Larsen, Beate Bersch, Paul Schanda
Structural basis of client specificity in mitochondrial membrane-protein chaperones. Science advances 6 (51) (2020)
Andreas Haahr Larsen, Yong Wang, Sandro Bottaro, Sergei Grudinin, Lise Arleth, Kresten Lindorff-Larsen
Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution. PLoS computational biology 16 (4) (2020)
Tone Bengtsen, Viktor L Holm, Lisbeth Ravnkilde Kjølbye, Søren R Midtgaard, Nicolai Tidemand Johansen, Giulio Tesei, Sandro Bottaro, Birgit Schiøtt, Lise Arleth, Kresten Lindorff-Larsen
Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations. eLife 9 (2020)
Lene Clausen, Amelie Stein, Martin Grønbæk-Thygesen, Lasse Nygaard, Cecilie L Søltoft, Sofie V Nielsen, Michael Lisby, Tommer Ravid, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation. PLoS genetics 16 (11) (2020)
Amanda B Abildgaard, Amelie Stein, Sofie V Nielsen, Katrine Schultz-Knudsen, Elena Papaleo, Amruta Shrikhande, Eva R Hoffmann, Inge Bernstein, Anne-Marie Gerdes, Masanobu Takahashi, Chikashi Ishioka, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. eLife 8 (2019)
Rasmus Scheller, Amelie Stein, Sofie V Nielsen, Frederikke I Marin, Anne-Marie Gerdes, Miriam Di Marco, Elena Papaleo, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations. Human mutation 40 (4) (2019)
Anne Kathrine Nielsen, Ingvar R Möller, Yong Wang, Søren G F Rasmussen, Kresten Lindorff-Larsen, Kasper Dyrberg Rand, Claus J Løland
Substrate-induced conformational dynamics of the dopamine transporter. Nature communications 10 (1) (2019)

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Kresten Lindorff-Larsen