Lena Marie Berger (Lena-Marie Berger, Lena M Berger)

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 27

Top Venues

Journal of medicinal chemistry

ACS chemical biology

International journal of molecular sciences

ACS pharmacology & translational science

Goethe University Frankfurt

Goethe University Frankfurt (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Goethe University Frankfurt

Germany

PhD Student :: Pharmacy

Merck KGaA

Germany

Working Student :: Discovery Pharmacology

Merck KGaA

Germany

Master Thesis :: Discovery Pharmacology

Merck KGaA

Germany

Internship Student :: Discovery Pharmacology

Goethe University Frankfurt

Germany

Internship Student :: RNA Structurbiology

Max Planck Institute of Colloids and Interfaces

Germany

Bachelor Thesis :: Structural Glycobiology

Structural Genomics Consortium

United Kingdom

Internship Student :: Protein Kinases

Education History

Goethe University Frankfurt

Germany

MSC :: Molecular Bioscience

Free University of Berlin

Germany

BSC :: Biology

Publications

Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry 67 (15) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry 67 (15) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry (2024)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry 67 (1) (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry 67 (1) (2023)
Jennifer A Amrhein, Guiqun Wang, Benedict-Tilmann Berger, Lena Marie Berger, Amalia D Kalampaliki, Andreas Krämer, Stefan Knapp, Thomas Hanke
Design and Synthesis of Pyrazole-Based Macrocyclic Kinase Inhibitors Targeting BMPR2. ACS medicinal chemistry letters 14 (6) (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry 67 (1) (2023)
Claudia Tredup, Benardina Ndreshkjana, Natalie S Schneider, Amelie Tjaden, Aurino M Kemas, Sonia Youhanna, Volker Martin Lauschke, Benedict-Tilmann Berger, Andreas Krämer, Lena Marie Berger, Sandra Röhm, Stefan Knapp, Henner F Farin, Susanne Müller
Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum. ACS chemical biology (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Amelie Tjaden, Andreas Krämer, Lewis Elson, Tuomas Tolvanen, Daniel Martinez-Molina, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Discovery of 3-Amino-1 H -pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family. International journal of molecular sciences 23 (23) (2022)
Jennifer Alisa Amrhein, Lena Marie Berger, Amelie Tjaden, Andreas Krämer, Lewis Elson, Tuomas Tolvanen, Daniel Martinez-Molina, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Discovery of 3-Amino-1 H -pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family. International journal of molecular sciences 23 (23) (2022)
Christian G Kurz, Franziska Preuss, Amelie Tjaden, Martin Cusack, Jennifer Alisa Amrhein, Deep Chatterjee, Sebastian Mathea, Lena Marie Berger, Benedict-Tilmann Berger, Andreas Krämer, Michael Weller, Tobias Weiss, Susanne Müller, Stefan Knapp, Thomas Hanke
Illuminating the Dark: Highly Selective Inhibition of Serine/Threonine Kinase 17A with Pyrazolo[1,5- a ]pyrimidine-Based Macrocycles. Journal of medicinal chemistry 65 (11) (2022)
Jennifer Alisa Amrhein, Lena Marie Berger, Amelie Tjaden, Andreas Krämer, Lewis Elson, Tuomas Tolvanen, Daniel Martinez-Molina, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Discovery of 3-Amino-1 H -pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family. International journal of molecular sciences 23 (23) (2022)
Jennifer Alisa Amrhein, Lena Marie Berger, Amelie Tjaden, Andreas Krämer, Lewis Elson, Tuomas Tolvanen, Daniel Martinez-Molina, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Discovery of 3-Amino-1 H -pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family. International journal of molecular sciences 23 (23) (2022)
Julian Laux, Michael Forster, Laura Riexinger, Anna Schwamborn, Jamil Guezguez, Christina Pokoj, Mark Kudolo, Lena Marie Berger, Stefan Knapp, Dieter Schollmeyer, Jan Guse, Michael Burnet, Stefan A Laufer
Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells. ACS pharmacology & translational science 5 (8) (2022)
Florian Wittlinger, David E Heppner, Ciric To, Marcel Günther, Bo Hee Shin, Jaimin K Rana, Anna M Schmoker, Tyler S Beyett, Lena Marie Berger, Benedict-Tilmann Berger, Nicolas Bauer, James D Vasta, Cesear R Corona, Matthew B Robers, Stefan Knapp, Pasi A Jänne, Michael J Eck, Stefan A Laufer
Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites. Journal of medicinal chemistry (2021)
Nicole Bata, Apirat Chaikuad, Nicole A Bakas, Allison S Limpert, Lester J Lambert, Douglas J Sheffler, Lena Marie Berger, Guoxiong Liu, Cunxiang Yuan, Li Wang, Yi Peng, Jing Dong, Maria Celeridad, Fabiana Layng, Stefan Knapp, Nicholas D P Cosford
Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia. Journal of medicinal chemistry (2021)
Roberta Tesch, Marcel Rak, Monika Raab, Lena Marie Berger, Thales Kronenberger, Andreas C Joerger, Benedict-Tilmann Berger, Ismahan Abdi, Thomas Hanke, Antti Poso, Klaus Strebhardt, Mourad Sanhaji, Stefan Knapp
Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. Journal of medicinal chemistry 64 (12) (2021)
Anja Dölle, Bikash Adhikari, Andreas Krämer, Janik Weckesser, Nicola Berner, Lena Marie Berger, Mathias Diebold, Magdalena M Szewczyk, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, Jakob Gebel, Frank Loehr, Volker Dötsch, Martin Eilers, Stephanie Wilhelm, Bernhard Kuster, Christoph A Sotriffer, Elmar Wolf, Stefan Knapp
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. Journal of medicinal chemistry 64 (15) (2021)
Thomas Hanke, Jong Fu Wong, Benedict-Tilmann Berger, Ismahan Abdi, Lena Marie Berger, Roberta Tesch, Claudia Tredup, Alex N Bullock, Susanne Müller, Stefan Knapp
A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5. ACS chemical biology 15 (4) (2020)

Lena Marie Berger.css-eqlu8i{font-size:small;padding-left:4px;} (Lena-Marie Berger, Lena M Berger)

Publication Activity (10 Years)

Top Topics

Top Venues

Lena Marie Berger (Lena-Marie Berger, Lena M Berger)