Christophe Romier

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 14

Top Topics

Endoplasmic Reticulum

Histone Deacetylase

Structure Activity Relationship

Childhood Cancer

Top Venues

Journal of medicinal chemistry

medRxiv : the preprint server for health sciences

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Arianna Colcerasa, Florian Friedrich, Jelena Melesina, Patrick Moser, Anja Vogelmann, Pavlos Tzortzoglou, Emilia Neuwirt, Manuela Sum, Dina Robaa, Lin Zhang, Elizabeth Ramos-Morales, Christophe Romier, Oliver Einsle, Eric Metzger, Roland Schüle, Olaf Groß, Wolfgang Sippl, Manfred Jung
Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD + -Dependent Lysine Deacylase Sirtuin 2. Journal of medicinal chemistry 67 (12) (2024)
Arianna Colcerasa, Florian Friedrich, Jelena Melesina, Patrick Moser, Anja Vogelmann, Pavlos Tzortzoglou, Emilia Neuwirt, Manuela Sum, Dina Robaa, Lin Zhang, Elizabeth Ramos-Morales, Christophe Romier, Oliver Einsle, Eric Metzger, Roland Schüle, Olaf Groß, Wolfgang Sippl, Manfred Jung
Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD + -Dependent Lysine Deacylase Sirtuin 2. Journal of medicinal chemistry (2024)
Arianna Colcerasa, Florian Friedrich, Jelena Melesina, Patrick Moser, Anja Vogelmann, Pavlos Tzortzoglou, Emilia Neuwirt, Manuela Sum, Dina Robaa, Lin Zhang, Elizabeth Ramos-Morales, Christophe Romier, Oliver Einsle, Eric Metzger, Roland Schüle, Olaf Groß, Wolfgang Sippl, Manfred Jung
Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD + -Dependent Lysine Deacylase Sirtuin 2. Journal of medicinal chemistry 67 (12) (2024)
Jordi Del-Pozo-Rodriguez, Peggy Tilly, Romain Lecat, Hugo Rolando Vaca, Laureline Mosser, Till Balla, Marina Vitoria Gomes, Elizabeth Ramos-Morales, Elena Brivio, Thalia Salinas-Giégé, Grace VanNoy, Eleina M England, Alysia Kern Lovgren, Melanie O'Leary, Maya Chopra, Dustin Gable, Aisha Alnuzha, Mona Kamel, Nihal Almenabawy, Anne H O'Donnell-Luria, Jennifer E Neil, Joseph G Gleeson, Christopher A Walsh, Nour Elkhateeb, Laila Selim, Siddharth Srivastava, Danny D Nedialkova, Laurence Drouard, Christophe Romier, Efil Bayam, Juliette D Godin
Neurodevelopmental disorders associated variants in ADAT3 disrupt the activity of the ADAT2/ADAT3 tRNA deaminase complex and impair neuronal migration. medRxiv : the preprint server for health sciences (2024)
Laura Sinatra, Anja Vogelmann, Florian Friedrich, Margarita A Tararina, Emilia Neuwirt, Arianna Colcerasa, Philipp König, Lara Toy, Talha Z Yesiloglu, Sebastian Hilscher, Lena Gaitzsch, Niklas Papenkordt, Shiyang Zhai, Lin Zhang, Christophe Romier, Oliver Einsle, Wolfgang Sippl, Mike Schutkowski, Olaf Gross, Gerd Bendas, David W Christianson, Finn K Hansen, Manfred Jung, Matthias Schiedel
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. Journal of medicinal chemistry (2023)
Daniel Herp, Johannes Ridinger, Dina Robaa, Stephen A Shinsky, Karin Schmidtkunz, Talha Z Yesiloglu, Theresa Bayer, Raphael R Steimbach, Corey J Herbst-Gervasoni, Annika Merz, Christophe Romier, Peter Sehr, Nikolas Gunkel, Aubry K Miller, David W Christianson, Ina Oehme, Wolfgang Sippl, Manfred Jung
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement. Chembiochem : a European journal of chemical biology 23 (14) (2022)
Ping Sun, Jing Wang, Khadija S Khan, Weiqin Yang, Billy Wai-Lung Ng, Nikita V Ilment, Matthes Zessin, Emre F Bülbül, Dina Robaa, Frank Erdmann, Matthias Schmidt, Christophe Romier, Mike Schutkowski, Alfred Sze-Lok Cheng, Wolfgang Sippl
Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties. Journal of medicinal chemistry (2022)
Salma Darwish, Tino Heimburg, Johannes Ridinger, Daniel Herp, Matthias Schmidt, Christophe Romier, Manfred Jung, Ina Oehme, Wolfgang Sippl
Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting Chimeras. Methods in molecular biology (Clifton, N.J.) 2589 (2022)
Sébastien Coassolo, Guillaume Davidson, Luc Negroni, Giovanni Gambi, Sylvain Daujat, Christophe Romier, Irwin Davidson
Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation. Nature communications 12 (1) (2021)
Elizabeth Ramos-Morales, Efil Bayam, Jordi Del-Pozo-Rodríguez, Thalia Salinas-Giegé, Martin Marek, Peggy Tilly, Philippe Wolff, Edouard Troesch, Eric Ennifar, Laurence Drouard, Juliette D Godin, Christophe Romier
The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic acids research 49 (11) (2021)
Matthes Zessin, Zsófia Kutil, Marat Meleshin, Zora Novakova, Ehab Ghazy, Diana Kalbas, Martin Marek, Christophe Romier, Wolfgang Sippl, Cyril Barinka, Mike Schutkowski
One-Atom Substitution Enables Direct and Continuous Monitoring of Histone Deacylase Activity. Biochemistry 58 (48) (2019)
Katharina Vögerl, Nghia Ong, Johanna Senger, Daniel Herp, Karin Schmidtkunz, Martin Marek, Martin Müller, Karin Bartel, Tajith Baba Shaik, Nicholas J Porter, Dina Robaa, David W Christianson, Christophe Romier, Wolfgang Sippl, Manfred Jung, Franz Bracher
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors. Journal of medicinal chemistry 62 (3) (2019)
Daria Monaldi, Dante Rotili, Julien Lancelot, Martin Marek, Nathalie Wössner, Alessia Lucidi, Daniela Tomaselli, Elizabeth Ramos-Morales, Christophe Romier, Raymond J Pierce, Antonello Mai, Manfred Jung
Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma mansoni (SmSirt2). Journal of medicinal chemistry 62 (19) (2019)
Martin Marek, Tajith B Shaik, Tino Heimburg, Alokta Chakrabarti, Julien Lancelot, Elizabeth Ramos-Morales, Cyrielle Da Veiga, Dmitrii Kalinin, Jelena Melesina, Dina Robaa, Karin Schmidtkunz, Takayoshi Suzuki, Ralph Holl, Eric Ennifar, Raymond J Pierce, Manfred Jung, Wolfgang Sippl, Christophe Romier
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. Journal of medicinal chemistry 61 (22) (2018)