Finn K Hansen

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Venues

Journal of medicinal chemistry

ChemMedChem

Pharmaceuticals (Basel, Switzerland)

ACS pharmacology & translational science

Leipzig University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leipzig University Nov 01 2016 - Jun 30 2020

Germany

Junior Professor :: Institute of Pharmacy

Publications

Mireia Toledano-Pinedo, Alicia Porro-Pérez, Linda Schäker-Hübner, Fernando Romero, Min Dong, Abdelouahid Samadi, Pedro Almendros, Isabel Iriepa, Òscar M Bautista-Aguilera, M Mercedes Rodríguez-Fernández, Cristina Solana-Manrique, Inmaculada Sanchis, Alba Mora-Morell, Ania Canseco Rodrìguez, Ana M Sànchez-Pérez, Damijan Knez, Stanislav Gobec, Aina Bellver-Sanchis, Belén Pérez, Alexey V Dobrydnev, Aizpea Artetxe-Zurutuza, Ander Matheu, Agata Siwek, Małgorzata Wolak, Grzegorz Satała, Andrzej J Bojarski, Agata Doroz-Płonka, Jadwiga Handzlik, Justyna Godyń, Anna Więckowska, Nuria Paricio, Christian Griñán-Ferré, Finn K Hansen, José Marco-Contelles
Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases. Journal of medicinal chemistry (2024)
Beate König, Finn K Hansen
2-(Difluoromethyl)-1,3,4-oxadiazoles: The Future of Selective Histone Deacetylase 6 Modulation? ACS pharmacology & translational science 7 (3) (2024)
Beate König, Finn K Hansen
2-(Difluoromethyl)-1,3,4-oxadiazoles: The Future of Selective Histone Deacetylase 6 Modulation? ACS pharmacology & translational science 7 (3) (2024)
Max E Huber, Silas L Wurnig, Aurélien F A Moumbock, Lara Toy, Evi Kostenis, Ana Alonso Bartolomé, Martyna Szpakowska, Andy Chevigné, Stefan Günther, Finn K Hansen, Matthias Schiedel
Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1. ChemMedChem (2024)
Felix Feller, Finn K Hansen
Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors. ACS medicinal chemistry letters 14 (12) (2023)
Christian Steinebach, Aleša Bricelj, Arunima Murgai, Gobec Izidor Sosič, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Valeriia Sapozhnikova, Annika Schmidt, Maximilian Rudolf Zuleeg, Patricia Lemnitzer, Philipp Mertins, Finn K Hansen, Michael Gütschow, Jan Krönke, Marcus D Hartmann
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. Journal of medicinal chemistry (2023)
Luisa Maria Gatzemeier, Maria Hanl, Felix Feller, Laura Sinatra, Andrea Schöler, Jens Pietzsch, Markus Laube, Finn K Hansen
Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors. Molecules (Basel, Switzerland) 28 (3) (2023)
Fabian B Kraft, Maria Hanl, Felix Feller, Linda Schäker-Hübner, Finn K Hansen
Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Luisa Maria Gatzemeier, Maria Hanl, Felix Feller, Laura Sinatra, Andrea Schöler, Jens Pietzsch, Markus Laube, Finn K Hansen
Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors. Molecules (Basel, Switzerland) 28 (3) (2023)
Felix Feller, Finn K Hansen
Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors. ACS medicinal chemistry letters 14 (12) (2023)
Beate König, Paris R Watson, Nina Reßing, Abigail D Cragin, Linda Schäker-Hübner, David W Christianson, Finn K Hansen
Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6 . Journal of medicinal chemistry (2023)
Laura Sinatra, Anja Vogelmann, Florian Friedrich, Margarita A Tararina, Emilia Neuwirt, Arianna Colcerasa, Philipp König, Lara Toy, Talha Z Yesiloglu, Sebastian Hilscher, Lena Gaitzsch, Niklas Papenkordt, Shiyang Zhai, Lin Zhang, Christophe Romier, Oliver Einsle, Wolfgang Sippl, Mike Schutkowski, Olaf Gross, Gerd Bendas, David W Christianson, Finn K Hansen, Manfred Jung, Matthias Schiedel
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. Journal of medicinal chemistry (2023)
Fabian B Kraft, Maria Hanl, Felix Feller, Linda Schäker-Hübner, Finn K Hansen
Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Luisa Maria Gatzemeier, Maria Hanl, Felix Feller, Laura Sinatra, Andrea Schöler, Jens Pietzsch, Markus Laube, Finn K Hansen
Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors. Molecules (Basel, Switzerland) 28 (3) (2023)
Max E Huber, Silas L Wurnig, Lara Toy, Corinna Weiler, Nicole Merten, Evi Kostenis, Finn K Hansen, Matthias Schiedel
Fluorescent Ligands Enable Target Engagement Studies for the Intracellular Allosteric Binding Site of the Chemokine Receptor CXCR2. Journal of medicinal chemistry (2023)
Fabian B Kraft, Maria Hanl, Felix Feller, Linda Schäker-Hübner, Finn K Hansen
Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Ki Back Chu, Hae-Ahm Lee, Marc Pflieger, Fabian Fischer, Yodita Asfaha, Leandro A Alves Avelar, Alexander Skerhut, Matthias U Kassack, Finn K Hansen, Andrea Schöler, Thomas Kurz, Min-Jeong Kim, Eun-Kyung Moon, Fu-Shi Quan
Antiproliferation and Antiencystation Effect of Class II Histone Deacetylase Inhibitors on Acanthamoeba castellanii . ACS infectious diseases 8 (2) (2022)
Linda Schäker-Hübner, Reza Haschemi, Thomas Büch, Fabian B Kraft, Birke Brumme, Andrea Schöler, Robert Jenke, Jens Meiler, Achim Aigner, Gerd Bendas, Finn K Hansen
Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors. ChemMedChem 17 (9) (2022)
Nina Reßing, Julian Schliehe-Diecks, Paris R Watson, Melf Sönnichsen, Abigail D Cragin, Andrea Schöler, Jing Yang, Linda Schäker-Hübner, Arndt Borkhardt, David W Christianson, Sanil Bhatia, Finn K Hansen
Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia. Journal of medicinal chemistry 65 (22) (2022)
Oliver Clauß, Linda Schäker-Hübner, Barbara Wenzel, Magali Toussaint, Winnie Deuther-Conrad, Daniel Gündel, Rodrigo Teodoro, Sladjana Dukić-Stefanović, Friedrich-Alexander Ludwig, Klaus Kopka, Peter Brust, Finn K Hansen, Matthias Scheunemann
Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [ 18 F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain. Pharmaceuticals (Basel, Switzerland) 15 (3) (2022)
Laura Sinatra, Jing Yang, Julian Schliehe-Diecks, Niklas Dienstbier, Melina Vogt, Philip Gebing, Luisa Maria Gatzemeier, Melf Sönnichsen, Thomas Lenz, Kai Stühler, Andrea Schöler, Arndt Borkhardt, Sanil Bhatia, Finn K Hansen
Solid-Phase Synthesis of Cereblon-Recruiting Selective Histone Deacetylase 6 Degraders (HDAC6 PROTACs) with Antileukemic Activity. Journal of medicinal chemistry (2022)
Lukas von Bredow, Thomas Martin Schäfer, Julian Hogenkamp, Maik Tretbar, Daniel Stopper, Fabian B Kraft, Julian Schliehe-Diecks, Andrea Schöler, Arndt Borkhardt, Sanil Bhatia, Jana Held, Finn K Hansen
Synthesis, Antiplasmodial, and Antileukemia Activity of Dihydroartemisinin-HDAC Inhibitor Hybrids as Multitarget Drugs. Pharmaceuticals (Basel, Switzerland) 15 (3) (2022)
Tim Keuler, Beate König, Nico Bückreiß, Fabian B Kraft, Philipp König, Linda Schäker-Hübner, Christian Steinebach, Gerd Bendas, Michael Gütschow, Finn K Hansen
Development of the first non-hydroxamate selective HDAC6 degraders. Chemical communications (Cambridge, England) 58 (79) (2022)
Anja Vogelmann, Manfred Jung, Finn K Hansen, Matthias Schiedel
Comparison of Cellular Target Engagement Methods for the Tubulin Deacetylases Sirt2 and HDAC6: NanoBRET, CETSA, Tubulin Acetylation, and PROTACs. ACS pharmacology & translational science 5 (2) (2022)
Sanil Bhatia, Lukas Spanier, David Bickel, Niklas Dienstbier, Vitalij Woloschin, Melina Vogt, Henrik Pols, Beate Lungerich, Jens Reiners, Narges Aghaallaei, Daniela Diedrich, Benedikt Frieg, Julian Schliehe-Diecks, Bertan Bopp, Franziska Lang, Mohanraj Gopalswamy, Jennifer Loschwitz, Baubak Bajoghli, Julia Skokowa, Arndt Borkhardt, Julia Hauer, Finn K Hansen, Sander H J Smits, Joachim Jose, Holger Gohlke, Thomas Kurz
Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization. ACS central science 8 (5) (2022)
Christa Elisabeth Müller, Finn K Hansen, Michael Gütschow, Dennis C Liotta, Courtney C Aldrich
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry , ACS Medicinal Chemistry Letters , and ACS Pharmacology & Translational Science . ACS pharmacology & translational science 4 (6) (2021)
Laura Sinatra, Lisa Kolano, Maik Icker, Stefan R Fritzsche, Daniela Volke, Ines Gockel, René Thieme, Ralf Hoffmann, Finn K Hansen
Hybrid Peptides Based on α-Aminoxy Acids as Antimicrobial and Anticancer Foldamers. ChemPlusChem 86 (6) (2021)
Linda Schäker-Hübner, Robin Warstat, Heinz Ahlert, Pankaj Mishra, Fabian B Kraft, Julian Schliehe-Diecks, Andrea Schöler, Arndt Borkhardt, Bernhard Breit, Sanil Bhatia, Martin Hügle, Stefan Günther, Finn K Hansen
4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads. Journal of medicinal chemistry 64 (19) (2021)
Christoph Selg, Andrea Schöler, Julian Schliehe-Diecks, Maria Hanl, Laura Sinatra, Arndt Borkhardt, Menyhárt-Botond Sárosi, Sanil Bhatia, Evamarie Hey-Hawkins, Finn K Hansen
Borinostats: solid-phase synthesis of carborane-capped histone deacetylase inhibitors with a tailor-made selectivity profile. Chemical science 12 (35) (2021)
Christa Elisabeth Müller, Finn K Hansen, Michael Gütschow, Dennis C Liotta, Courtney C Aldrich
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science. Journal of medicinal chemistry 64 (19) (2021)
Marc Pflieger, Melf Sönnichsen, Nadine Horstick-Muche, Jing Yang, Julian Schliehe-Diecks, Andrea Schöler, Arndt Borkhardt, Alexandra Hamacher, Matthias U Kassack, Finn K Hansen, Sanil Bhatia, Thomas Kurz
Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity. ChemMedChem 16 (11) (2021)
Christa Elisabeth Müller, Finn K Hansen, Michael Gütschow, Dennis C Liotta, Courtney C Aldrich
New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science. ACS medicinal chemistry letters 12 (10) (2021)
Laura Sinatra, Jan J Bandolik, Martin Roatsch, Melf Sönnichsen, Clara T Schoeder, Alexandra Hamacher, Andrea Schöler, Arndt Borkhardt, Jens Meiler, Sanil Bhatia, Matthias U Kassack, Finn K Hansen
Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of Dual-Targeting HDAC Inhibitors and HDAC Degraders (PROTACs). Angewandte Chemie (International ed. in English) 59 (50) (2020)
Nina Reßing, Melf Sönnichsen, Jeremy D Osko, Andrea Schöler, Julian Schliehe-Diecks, Alexander Skerhut, Arndt Borkhardt, Julia Hauer, Matthias U Kassack, David W Christianson, Sanil Bhatia, Finn K Hansen
Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups. Journal of medicinal chemistry 63 (18) (2020)
Marcel K W Mackwitz, Eva Hesping, Yevgeniya Antonova-Koch, Daniela Diedrich, Tamirat Gebru Woldearegai, Tina Skinner-Adams, Mary Clarke, Andrea Schöler, Laura Limbach, Thomas Kurz, Elizabeth A Winzeler, Jana Held, Katherine T Andrews, Finn K Hansen
Structure-Activity and Structure-Toxicity Relationships of Peptoid-Based Histone Deacetylase Inhibitors with Dual-Stage Antiplasmodial Activity. ChemMedChem 14 (9) (2019)
Viktoria Krieger, Alexandra Hamacher, Fangyuan Cao, Katharina Stenzel, Christoph G W Gertzen, Linda Schäker-Hübner, Thomas Kurz, Holger Gohlke, Frank J Dekker, Matthias U Kassack, Finn K Hansen
Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties. Journal of medicinal chemistry 62 (24) (2019)
Sanil Bhatia, Viktoria Krieger, Michael Groll, Jeremy D Osko, Nina Reßing, Heinz Ahlert, Arndt Borkhardt, Thomas Kurz, David W Christianson, Julia Hauer, Finn K Hansen
Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. Journal of medicinal chemistry 61 (22) (2018)
Aline Kaletsch, Maria Pinkerneil, Michèle Janine Hoffmann, Ananda Ayyappan Jaguva Vasudevan, Chenyin Wang, Finn K Hansen, Constanze Wiek, Helmut Hanenberg, Christoph G W Gertzen, Holger Gohlke, Matthias Ulrich Kassack, Thomas Kurz, Wolfgang A Schulz, Guenter Niegisch
Effects of novel HDAC inhibitors on urothelial carcinoma cells. Clinical epigenetics 10 (1) (2018)
Marcel K W Mackwitz, Alexandra Hamacher, Jeremy D Osko, Jana Held, Andrea Schöler, David W Christianson, Matthias U Kassack, Finn K Hansen
Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors. Organic letters 20 (11) (2018)
Sanil Bhatia, Daniela Diedrich, Benedikt Frieg, Heinz Ahlert, Stefan Stein, Bertan Bopp, Franziska Lang, Tao Zang, Tobias Kröger, Thomas Ernst, Gesine Kögler, Andreas Krieg, Steffen Lüdeke, Hana Kunkel, Ana J Rodrigues Moita, Matthias U Kassack, Viktoria Marquardt, Friederike V Opitz, Marina Oldenburg, Marc Remke, Florian Babor, Manuel Grez, Andreas Hochhaus, Arndt Borkhardt, Georg Groth, Luitgard Nagel-Steger, Joachim Jose, Thomas Kurz, Holger Gohlke, Finn K Hansen, Julia Hauer
Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response. Blood 132 (3) (2018)
Nina Reßing, Viktoria Marquardt, Christoph G W Gertzen, Andrea Schöler, Alexander Schramm, Thomas Kurz, Holger Gohlke, Achim Aigner, Marc Remke, Finn K Hansen
Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity. MedChemComm 10 (7) (2018)
Katharina Stenzel, Ming Jang Chua, Sandra Duffy, Yevgeniya Antonova-Koch, Stephan Meister, Alexandra Hamacher, Matthias U Kassack, Elizabeth Winzeler, Vicky M Avery, Thomas Kurz, Katherine T Andrews, Finn K Hansen
Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-Plasmodium Activity. ChemMedChem 12 (19) (2017)
Viktoria Krieger, Emanuele Ciglia, Roland Thoma, Vera Vasylyeva, Benedikt Frieg, Nader de Sousa Amadeu, Thomas Kurz, Ulf Dietrich Kahlert, Holger Gohlke, Finn K Hansen
α-Aminoxy Peptoids: A Unique Peptoid Backbone with a Preference for cis-Amide Bonds. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (15) (2017)
Katharina Stenzel, Alexandra Hamacher, Finn K Hansen, Christoph G W Gertzen, Johanna Senger, Viktoria Marquardt, Linda Marek, Martin Marek, Christophe Romier, Marc Remke, Manfred Jung, Holger Gohlke, Matthias U Kassack, Thomas Kurz
Alkoxyurea-Based Histone Deacetylase Inhibitors Increase Cisplatin Potency in Chemoresistant Cancer Cell Lines. Journal of medicinal chemistry 60 (13) (2017)
Viktoria Krieger, Alexandra Hamacher, Christoph G W Gertzen, Johanna Senger, Martijn R H Zwinderman, Martin Marek, Christophe Romier, Frank J Dekker, Thomas Kurz, Manfred Jung, Holger Gohlke, Matthias U Kassack, Finn K Hansen
Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups. Journal of medicinal chemistry 60 (13) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Finn K Hansen