David R Sibley

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Topics

Structural Basis

Binding Protein

Top Venues

Pharmacological reviews

Molecular psychiatry

ACS pharmacology & translational science

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

David R Sibley
The Enduring Impact of Pharmacological Reviews -Editorial. Pharmacological reviews 76 (5) (2024)
David R Sibley
The Enduring Impact of Pharmacological Reviews -Editorial. Pharmacological reviews 76 (5) (2024)
David R Sibley
The Enduring Impact of Pharmacological Reviews -Editorial. Pharmacological reviews 76 (5) (2024)
David R Sibley
The Enduring Impact of Pharmacological Reviews -Editorial. Pharmacological reviews 76 (5) (2024)
Comfort A Boateng, Ashley N Nilson, Rebekah Placide, Mimi L Pham, Franziska M Jakobs, Noelia M Boldizsar, Scot McIntosh, Leia S Stallings, Ivana V Korankyi, Shreya Kelshikar, Nisha Shah, Diandra Panasis, Abigail Muccilli, Maria Ladik, Brianna Maslonka, Connor McBride, Moises Ximello Sanchez, Ebrar Akca, Mohammad Alkhatib, Julianna Saez, Catherine Nguyen, Emily Kurtyan, Jacquelyn DePierro, Raymond Crowthers, Dylan Brunt, Alessandro Bonifazi, Amy Hauck Newman, Rana Rais, Barbara S Slusher, R Benjamin Free, David R Sibley, Kent D Stewart, Chun Wu, Scott E Hemby, Thomas M Keck
Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder. Journal of medicinal chemistry (2023)
Amy E Moritz, Nora S Madaras, Michele L Rankin, Laura R Inbody, David R Sibley
Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D 1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation. International journal of molecular sciences 24 (7) (2023)
Juan Enriquez-Traba, Hector E Yarur, Rodolfo J Flores, Tenley Weil, Snehashis Roy, Ted B Usdin, Christina T LaGamma, Miguel Arenivar, Huikun Wang, Valerie S Tsai, Amy E Moritz, David R Sibley, Rosario Moratalla, Zachary Z Freyberg, Hugo A Tejeda
Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. bioRxiv : the preprint server for biology (2023)
Marta Sánchez-Soto, Noelia M Boldizsar, Kayla A Schardien, Nora S Madaras, Blair K A Willette, Laura R Inbody, Christopher Dasaro, Amy E Moritz, Julia Drube, Raphael S Haider, R Benjamin Free, Carsten Hoffmann, David R Sibley
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D 2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation. Biomolecules 13 (10) (2023)
Jordi Bonaventura, Juan L Gomez, Meghan L Carlton, Sherry Lam, Marta Sanchez-Soto, Patrick J Morris, Ruin Moaddel, Hye Jin Kang, Panos Zanos, Todd D Gould, Craig J Thomas, David R Sibley, Carlos A Zarate, Michael Michaelides
Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search. Molecular psychiatry 27 (10) (2022)
Jordi Bonaventura, Sherry Lam, Meghan Carlton, Matthew Boehm, Juan L Gomez, Oscar Solis, Marta Sánchez-Soto, Patrick J Morris, Ida Fredriksson, Craig J Thomas, David R Sibley, Yavin Shaham, Carlos A Zarate, Michael Michaelides
The show must go on. Reply to "Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al" by Insop Shim. Molecular psychiatry (2022)
R Benjamin Free, Ashley N Nilson, Noelia M Boldizsar, Trevor B Doyle, Ramona M Rodriguiz, Vladimir M Pogorelov, Mayako Machino, Kuo Hao Lee, Jeremiah W Bertz, Jinbin Xu, Herman D Lim, Andrés E Dulcey, Robert H Mach, James H Woods, J Robert Lane, Lei Shi, Juan Jose Marugan, William C Wetsel, David R Sibley
Identification and Characterization of ML321: A Novel and Highly Selective D 2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity. ACS pharmacology & translational science 6 (1) (2022)
R Benjamin Free, Ashley N Nilson, Noelia M Boldizsar, Trevor B Doyle, Ramona M Rodriguiz, Vladimir M Pogorelov, Mayako Machino, Kuo Hao Lee, Jeremiah W Bertz, Jinbin Xu, Herman D Lim, Andrés E Dulcey, Robert H Mach, James H Woods, J Robert Lane, Lei Shi, Juan Jose Marugan, William C Wetsel, David R Sibley
Identification and Characterization of ML321: A Novel and Highly Selective D 2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity. ACS pharmacology & translational science 6 (1) (2022)
Jordi Bonaventura, Sherry Lam, Meghan Carlton, Matthew Boehm, Juan L Gomez, Oscar Solis, Marta Sánchez-Soto, Patrick J Morris, Ida Fredriksson, Craig J Thomas, David R Sibley, Yavin Shaham, Carlos A Zarate, Michael Michaelides
Time will tell. Reply to "Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al." by Chen et al. Molecular psychiatry 27 (4) (2022)
David R Sibley, Kathryn D Luderman, R Benjamin Free, Lei Shi
Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential. Signal transduction and targeted therapy 6 (1) (2021)
Jordi Bonaventura, Sherry Lam, Meghan Carlton, Matthew A Boehm, Juan L Gomez, Oscar Solís, Marta Sánchez-Soto, Patrick J Morris, Ida Fredriksson, Craig J Thomas, David R Sibley, Yavin Shaham, Carlos A Zarate, Michael Michaelides
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability. Molecular psychiatry (2021)
Despoina Aslanoglou, Suzanne Bertera, Marta Sánchez-Soto, R Benjamin Free, Jeongkyung Lee, Wei Zong, Xiangning Xue, Shristi Shrestha, Marcela Brissova, Ryan W Logan, Claes B Wollheim, Massimo Trucco, Vijay K Yechoor, David R Sibley, Rita Bottino, Zachary Z Freyberg
Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors. Translational psychiatry 11 (1) (2021)
Amy E Moritz, Alessandro Bonifazi, Adrian M Guerrero, Vivek Kumar, R Benjamin Free, J Robert Lane, Ravi Kumar Verma, Lei Shi, Amy Hauck Newman, David R Sibley
Evidence for a Stereoselective Mechanism for Bitopic Activity by Extended-Length Antagonists of the D3 Dopamine Receptor. ACS chemical neuroscience 11 (20) (2020)
Marta Sánchez-Soto, Ravi Kumar Verma, Blair K A Willette, Elizabeth C Gonye, Annah M Moore, Amy E Moritz, Comfort A Boateng, Hideaki Yano, R Benjamin Free, Lei Shi, David R Sibley
A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science signaling 13 (617) (2020)
Amy E Moritz, R Benjamin Free, Warren S Weiner, Emmanuel O Akano, Disha Gandhi, Ara Abramyan, Thomas M Keck, Marc Ferrer, Xin Hu, Noel Southall, Joseph Steiner, Jeffrey Aube, Lei Shi, Kevin J Frankowski, David R Sibley
Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist. Journal of medicinal chemistry 63 (10) (2020)
Richard Ågren, Hugo Zeberg, Tomasz Maciej Stępniewski, R Benjamin Free, Sean W Reilly, Robert R Luedtke, Peter Århem, Francisco Ciruela, David R Sibley, Robert H Mach, Jana Selent, Johanna Nilsson, Kristoffer Sahlholm
Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism. ACS chemical neuroscience 11 (19) (2020)
Jordi Bonaventura, Mark A G Eldridge, Feng Hu, Juan L Gomez, Marta Sanchez-Soto, Ara M Abramyan, Sherry Lam, Matthew A Boehm, Christina Ruiz, Mitchell R Farrell, Andrea Moreno, Islam Mustafa Galal Faress, Niels Andersen, John Y Lin, Ruin Moaddel, Patrick J Morris, Lei Shi, David R Sibley, Stephen V Mahler, Sadegh Nabavi, Martin G Pomper, Antonello Bonci, Andrew G Horti, Barry J Richmond, Michael Michaelides
High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature communications 10 (1) (2019)