David Malkin

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 51

Top Topics

Childhood Cancer

Top Venues

Nature communications

Cell death and differentiation

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Yoshiko Nakano, Meryl Acker, Harriet Druker, Kalene van Engelen, M Stephen Meyn, Jonathan D Wasserman, Rosemarie E Venier, Catherine Goudie, Ana Stosic, Annie Huang, Mary-Louise C Greer, David Malkin, Anita Villani, Bailey Gallinger
Late-onset tumors in rhabdoid tumor predisposition syndrome type-1 (RTPS1) and implications for surveillance. European journal of human genetics : EJHG (2024)
Christian Peter Kratz, Philip J Lupo, Kristin Zelley, Jaclyn Schienda, Kim E Nichols, Douglas R Stewart, David Malkin, Garrett M Brodeur, Kara N Maxwell, Sharon E Plon, Michael F Walsh
Adult-Onset Cancer Predisposition Syndromes in Children and Adolescents-To Test or not to Test? Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Himanshi Agarwal, Perry Tal, Naomi Goldfinger, Esita Chattopadhyay, David Malkin, Varda Rotter, Ayush Attery
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts. Cell death and differentiation (2024)
Derek Wong, Maha Tageldein, Ping Luo, Erik Ensminger, Jeffrey Bruce, Leslie Oldfield, Haifan Gong, Nicholas William Fischer, Brianne Laverty, Vallijah Subasri, Scott Davidson, Reem Khan, Anita Villani, Adam Shlien, Raymond H Kim, David Malkin, Trevor J Pugh
Cell-free DNA from germline TP53 mutation carriers reflect cancer-like fragmentation patterns. Nature communications 15 (1) (2024)
Derek Wong, Maha Tageldein, Ping Luo, Erik Ensminger, Jeffrey Bruce, Leslie Oldfield, Haifan Gong, Nicholas William Fischer, Brianne Laverty, Vallijah Subasri, Scott Davidson, Reem Khan, Anita Villani, Adam Shlien, Raymond H Kim, David Malkin, Trevor J Pugh
Cell-free DNA from germline TP53 mutation carriers reflect cancer-like fragmentation patterns. Nature communications 15 (1) (2024)
Himanshi Agarwal, Perry Tal, Naomi Goldfinger, Esita Chattopadhyay, David Malkin, Varda Rotter, Ayush Attery
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts. Cell death and differentiation 31 (7) (2024)
Himanshi Agarwal, Perry Tal, Naomi Goldfinger, Esita Chattopadhyay, David Malkin, Varda Rotter, Ayush Attery
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts. Cell death and differentiation 31 (7) (2024)
Himanshi Agarwal, Perry Tal, Naomi Goldfinger, Esita Chattopadhyay, David Malkin, Varda Rotter, Ayush Attery
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts. Cell death and differentiation 31 (7) (2024)
Sarah Margaret Goodday, Emma Karlin, Alexa Brooks, Carol Chapman, Christiana Harry, Nelly Lugo, Shannon Peabody, Shazia Rangwala, Ella Swanson, Jonell Tempero, Robin Yang, Daniel R Karlin, Ron Rabinowicz, David Malkin, Simon P L Travis, Alissa Walsh, Robert P Hirten, Bruce E Sands, Chetan Bettegowda, Matthias Holdhoff, Jessica Wollett, Kelly Szajna, Kallan Dirmeyer, Anna Dodd, Shawn Hutchinson, Stephanie Ramotar, Robert C Grant, Adrien Boch, Mackenzie Wildman, Stephen H Friend
Value of Engagement in Digital Health Technology Research: Evidence Across 6 Unique Cohort Studies. Journal of medical Internet research 26 (2024)
Christian Peter Kratz, Philip J Lupo, Kristin Zelley, Jaclyn Schienda, Kim E Nichols, Douglas R Stewart, David Malkin, Garrett M Brodeur, Kara N Maxwell, Sharon E Plon, Michael F Walsh
Adult-onset cancer predisposition syndromes in children and adolescents - to test or not to test? Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Mary-Louise C Greer, Lisa J States, David Malkin, Stephan D Voss, Andrea Schwarz Doria
Update on Whole-body MRI Surveillance for Pediatric Cancer Predisposition Syndromes. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Derek Wong, Maha Tageldein, Ping Luo, Erik Ensminger, Jeffrey Bruce, Leslie Oldfield, Haifan Gong, Nicholas William Fischer, Brianne Laverty, Vallijah Subasri, Scott Davidson, Reem Khan, Anita Villani, Adam Shlien, Raymond H Kim, David Malkin, Trevor J Pugh
Cell-free DNA from germline TP53 mutation carriers reflect cancer-like fragmentation patterns. Nature communications 15 (1) (2024)
Christian Peter Kratz, Philip J Lupo, Kristin Zelley, Jaclyn Schienda, Kim E Nichols, Douglas R Stewart, David Malkin, Garrett M Brodeur, Kara N Maxwell, Sharon E Plon, Michael F Walsh
Adult-Onset Cancer Predisposition Syndromes in Children and Adolescents-To Test or not to Test? Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Federico Comitani, Joshua O Nash, Sarah Cohen-Gogo, Astra I Chang, Timmy T Wen, Anant Maheshwari, Bipasha Goyal, Earvin S Tio, Kevin Tabatabaei, Chelsea Mayoh, Regis Zhao, Ben Ho, Ledia Brunga, John E G Lawrence, Petra Balogh, Adrienne M Flanagan, Sarah A Teichmann, Annie Huang, Vijay Ramsawami, Johann K Hitzler, Jonathan D Wasserman, Rebecca A Gladdy, Brendan C Dickson, Uri Tabori, Mark J Cowley, Sam Behjati, David Malkin, Anita Villani, Meredith S Irwin, Adam Shlien
Diagnostic classification of childhood cancer using multiscale transcriptomics. Nature medicine 29 (3) (2023)
Federico Comitani, Joshua O Nash, Sarah Cohen-Gogo, Astra I Chang, Timmy T Wen, Anant Maheshwari, Bipasha Goyal, Earvin S Tio, Kevin Tabatabaei, Chelsea Mayoh, Regis Zhao, Ben Ho, Ledia Brunga, John E G Lawrence, Petra Balogh, Adrienne M Flanagan, Sarah A Teichmann, Annie Huang, Vijay Ramsawami, Johann K Hitzler, Jonathan D Wasserman, Rebecca A Gladdy, Brendan C Dickson, Uri Tabori, Mark J Cowley, Sam Behjati, David Malkin, Anita Villani, Meredith S Irwin, Adam Shlien
Diagnostic classification of childhood cancer using multiscale transcriptomics. Nature medicine (2023)
Vallijah Subasri, Nicholas Light, Nisha Kanwar, Jack J Brzezinski, Ping Luo, Jordan R Hansford, Elizabeth Cairney, Carol Portwine, Christine Elser, Jonathan L Finlay, Kim E Nichols, Noa Alon, Ledia Brunga, Jo Anson, Wendy K Kohlmann, Kelvin César de Andrade, Payal P Khincha, Sharon A Savage, Joshua D Schiffman, Rosanna Weksberg, Trevor J Pugh, Anita Villani, Adam Shlien, Anna Goldenberg, David Malkin
Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome. Cancer research communications 3 (5) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Derek Wong, Ping Luo, Leslie E Oldfield, Haifan Gong, Ledia Brunga, Ron Rabinowicz, Vallijah Subasri, Clarissa Chan, Tiana Downs, Kirsten M Farncombe, Beatrice Luu, Maia Leigh Norman, Julia A Sobotka, Precious Uju, Jenna Eagles, Stephanie Pedersen, Johanna Wellum, Arnavaz Danesh, Stephenie D Prokopec, Eric Y Zhao, Nadia Znassi, Lawrence E Heisler, Richard Jovelin, Bernard Lam, Beatriz E Lujan-Toro, Kayla Marsh, Yogi Sundaravadanam, Dax Torti, Carina Man, Anna Goldenberg, Wei Xu, Patrick Veit-Haibach, Andrea Schwarz Doria, David Malkin, Raymond H Kim, Trevor J Pugh
Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA. Cancer discovery (2023)
Vallijah Subasri, Nicholas Light, Nisha Kanwar, Jack J Brzezinski, Ping Luo, Jordan R Hansford, Elizabeth Cairney, Carol Portwine, Christine Elser, Jonathan L Finlay, Kim E Nichols, Noa Alon, Ledia Brunga, Jo Anson, Wendy K Kohlmann, Kelvin César de Andrade, Payal P Khincha, Sharon A Savage, Joshua D Schiffman, Rosanna Weksberg, Trevor J Pugh, Anita Villani, Adam Shlien, Anna Goldenberg, David Malkin
Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome. Cancer research communications 3 (5) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Federico Comitani, Joshua O Nash, Sarah Cohen-Gogo, Astra I Chang, Timmy T Wen, Anant Maheshwari, Bipasha Goyal, Earvin S Tio, Kevin Tabatabaei, Chelsea Mayoh, Regis Zhao, Ben Ho, Ledia Brunga, John E G Lawrence, Petra Balogh, Adrienne M Flanagan, Sarah A Teichmann, Annie Huang, Vijay Ramsawami, Johann K Hitzler, Jonathan D Wasserman, Rebecca A Gladdy, Brendan C Dickson, Uri Tabori, Mark J Cowley, Sam Behjati, David Malkin, Anita Villani, Meredith S Irwin, Adam Shlien
Diagnostic classification of childhood cancer using multiscale transcriptomics. Nature medicine 29 (3) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Vallijah Subasri, Nicholas Light, Nisha Kanwar, Jack J Brzezinski, Ping Luo, Jordan R Hansford, Elizabeth Cairney, Carol Portwine, Christine Elser, Jonathan L Finlay, Kim E Nichols, Noa Alon, Ledia Brunga, Jo Anson, Wendy K Kohlmann, Kelvin César de Andrade, Payal P Khincha, Sharon A Savage, Joshua D Schiffman, Rosanna Weksberg, Trevor J Pugh, Anita Villani, Adam Shlien, Anna Goldenberg, David Malkin
Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome. Cancer research communications 3 (5) (2023)
Vallijah Subasri, Nicholas Light, Nisha Kanwar, Jack J Brzezinski, Ping Luo, Jordan R Hansford, Elizabeth Cairney, Carol Portwine, Christine Elser, Jonathan L Finlay, Kim E Nichols, Noa Alon, Ledia Brunga, Jo Anson, Wendy K Kohlmann, Kelvin César de Andrade, Payal P Khincha, Sharon A Savage, Joshua D Schiffman, Rosanna Weksberg, Trevor J Pugh, Anita Villani, Adam Shlien, Anna Goldenberg, David Malkin
Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome. Cancer research communications 3 (5) (2023)
Vallijah Subasri, Nicholas Light, Nisha Kanwar, Jack J Brzezinski, Ping Luo, Jordan R Hansford, Elizabeth Cairney, Carol Portwine, Christine Elser, Jonathan L Finlay, Kim E Nichols, Noa Alon, Ledia Brunga, Jo Anson, Wendy K Kohlmann, Kelvin César de Andrade, Payal P Khincha, Sharon A Savage, Joshua D Schiffman, Rosanna Weksberg, Trevor J Pugh, Anita Villani, Adam Shlien, Anna Goldenberg, David Malkin
Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome. Cancer research communications 3 (5) (2023)
Anirban Das, Nicholas R Fernandez, Adrian B Levine, Vanessa Bianchi, Lucie K Stengs, Jiil Chung, Logine Negm, Jose Rafael Dimayacyac, Yuan Chang, Liana Nobre, Ayse Bahar Ercan, Santiago Sánchez-Ramírez, Sumedha Sudhaman, Melissa Edwards, Larouche Valérie, David Samuel, An Van Damme, David Gass, David S Ziegler, Stefan S Bielack, Carl J Koschmann, Shayna Zelcer, Michal Yalon-Oren, Gadi Abede Campino, Tomasz Sarosiek, Kim E Nichols, Rebecca Loret De Mola, Kevin Bielamowicz, Magnus Sabel, Charlotta A Frojd, Matthew D Wood, Jason M Glover, Yi-Yen Lee, Magimairajan Issai Vanan, Jenny K Adamski, Sébastien Perreault, Omar Chamdine, Magnus Aassved Hjort, Michal Zápotocký, Fernando Carceller, Erin Wright, Ivana Fedorakova, Alexander Lossos, Ryuma Tanaka, Michael Philip Osborn, Deborah T Blumenthal, Melyssa Aronson, Ute Bartels, Annie Huang, Vijay Ramsawami, David Malkin, Adam Shlien, Anita Villani, Peter B Dirks, Trevor J Pugh, Gad A Getz, Yosef E Maruvka, Derek S Tsang, Birgit Betina Ertl-Wagner, Cynthia Hawkins, Eric Bouffet, Daniel A Morgenstern, Uri Tabori
Combined immunotherapy improves outcome for replication repair deficient (RRD) high-grade glioma failing anti-PD1 monotherapy: A report from the International RRD Consortium. Cancer discovery (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Federico Comitani, Joshua O Nash, Sarah Cohen-Gogo, Astra I Chang, Timmy T Wen, Anant Maheshwari, Bipasha Goyal, Earvin S Tio, Kevin Tabatabaei, Chelsea Mayoh, Regis Zhao, Ben Ho, Ledia Brunga, John E G Lawrence, Petra Balogh, Adrienne M Flanagan, Sarah A Teichmann, Annie Huang, Vijay Ramsawami, Johann K Hitzler, Jonathan D Wasserman, Rebecca A Gladdy, Brendan C Dickson, Uri Tabori, Mark J Cowley, Sam Behjati, David Malkin, Anita Villani, Meredith S Irwin, Adam Shlien
Diagnostic classification of childhood cancer using multiscale transcriptomics. Nature medicine 29 (3) (2023)
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D Anderson, Arun K Ramani, Kyoko E Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D Wasserman, Rosemarie E Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A Whitlock, Stephen W Scherer, Kathy Chun, Martin J Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramsawami, Gino R Somers, Lianna Kyriakopoulou, Johann K Hitzler, Mary Shago, Daniel A Morgenstern, Uri Tabori, Stephen Meyn, Meredith S Irwin, David Malkin, Adam Shlien
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations. Nature cancer (2022)
Liam D Hendrikse, Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H Sjoboen, Anders Wilder Erickson, Winnie Ong, Victor Gordon, Ludivine Coudière-Morrison, Audrey L Mercier, Mohammad Shokouhian, Raúl A Suárez, Michelle Ly, Stephanie Borlase, David S Scott, Maria C Vladoiu, Hamza Farooq, Olga Sirbu, Takuma Nakashima, Shohei Nambu, Yusuke Funakoshi, Alec Bahcheli, J Javier Diaz-Mejia, Joseph Golser, Kathleen Bach, Tram Phuong-Bao, Patryk Skowron, Evan Y Wang, Sachin A Kumar, Polina Balin, Abhirami Visvanathan, John J Y Lee, Ramy Ayoub, Xin Chen, Xiaodi Chen, Karen L Mungall, Betty Luu, Pierre Bérubé, Yu C Wang, Stefan M Pfister, Seung-Ki Kim, Olivier O Delattre, Franck Bourdeaut, François Doz, Julien Masliah-Planchon, Wieslawa A Grajkowska, James Loukides, Peter B Dirks, Michelle Fèvre-Montange, Anne Jouvet, Pim J French, Johan M Kros, Karel Zitterbart, Swneke D Bailey, Charles G Eberhart, Amulya A N Rao, Caterina Giannini, James M Olson, Miklós Garami, Peter Hauser, Joanna J Phillips, Young S Ra, Carmen de Torres, Jaume Mora, Kay K W Li, Ho-Keung Ng, Wai S Poon, Ian F Pollack, Enrique López-Aguilar, G Yancey Gillespie, Timothy E Van Meter, Tomoko Shofuda, Rajeev Vibhakar, Reid C Thompson, Michael K Cooper, Joshua B Rubin, Toshihiro Kumabe, Shin Jung, Boleslaw Lach, Achille Iolascon, Veronica Ferrucci, Pasqualino de Antonellis, Massimo Zollo, Giuseppe Cinalli, Shenandoah Robinson, Duncan S Stearns, Erwin G Van Meir, Paola Porrati, Gaetano Finocchiaro, Maura Massimino, Carlos G Carlotti, Claudia C Faria, Martine F Roussel, Frederick Boop, Jennifer A Chan, Kimberly A Aldinger, Ferechte Razavi, Evelina Silvestri, Roger E McLendon, Eric Michael Thompson, Marc Ansari, Maria L Garre, Fernando Chico, Pilar Eguía, Mario Pérezpeña, A Sorana Morrissy, Florence M G Cavalli, Xiaochong Wu, Craig Daniels, Jeremy N Rich, Steven J M Jones, Richard A Moore, Marco A Marra, Xi Huang, Jüri Reimand, Poul H Sorensen, Robert J Wechsler-Reya, William A Weiss, Trevor J Pugh, Livia Garzia, Claudia L Kleinman, Lincoln D Stein, Nada Jabado, David Malkin, Olivier Ayrault, Jeffrey A Golden, David W Ellison, Bradley W Doble, Vijay Ramsawami, Tamra E Werbowetski-Ogilvie, Hiromichi Suzuki, Kathleen J Millen, Michael D Taylor
Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature 609 (7929) (2022)
Kelvin César de Andrade, Elaine E Lee, Elise M Tookmanian, Chimene A Kesserwan, James J Manfredi, Jessica N Hatton, Jennifer K Loukissas, Jiri Zavadil, Lei Zhou, Magali Olivier, Megan N Frone, Owais Shahzada, William J R Longabaugh, Christian P Kratz, David Malkin, Pierre Hainaut, Sharon A Savage
The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute. Cell death and differentiation 29 (5) (2022)
Liam D Hendrikse, Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H Sjoboen, Anders Wilder Erickson, Winnie Ong, Victor Gordon, Ludivine Coudière-Morrison, Audrey L Mercier, Mohammad Shokouhian, Raúl A Suárez, Michelle Ly, Stephanie Borlase, David S Scott, Maria C Vladoiu, Hamza Farooq, Olga Sirbu, Takuma Nakashima, Shohei Nambu, Yusuke Funakoshi, Alec Bahcheli, J Javier Diaz-Mejia, Joseph Golser, Kathleen Bach, Tram Phuong-Bao, Patryk Skowron, Evan Y Wang, Sachin A Kumar, Polina Balin, Abhirami Visvanathan, John J Y Lee, Ramy Ayoub, Xin Chen, Xiaodi Chen, Karen L Mungall, Betty Luu, Pierre Bérubé, Yu C Wang, Stefan M Pfister, Seung-Ki Kim, Olivier O Delattre, Franck Bourdeaut, François Doz, Julien Masliah-Planchon, Wieslawa A Grajkowska, James Loukides, Peter B Dirks, Michelle Fèvre-Montange, Anne Jouvet, Pim J French, Johan M Kros, Karel Zitterbart, Swneke D Bailey, Charles G Eberhart, Amulya A N Rao, Caterina Giannini, James M Olson, Miklós Garami, Peter Hauser, Joanna J Phillips, Young S Ra, Carmen de Torres, Jaume Mora, Kay K W Li, Ho-Keung Ng, Wai S Poon, Ian F Pollack, Enrique López-Aguilar, G Yancey Gillespie, Timothy E Van Meter, Tomoko Shofuda, Rajeev Vibhakar, Reid C Thompson, Michael K Cooper, Joshua B Rubin, Toshihiro Kumabe, Shin Jung, Boleslaw Lach, Achille Iolascon, Veronica Ferrucci, Pasqualino de Antonellis, Massimo Zollo, Giuseppe Cinalli, Shenandoah Robinson, Duncan S Stearns, Erwin G Van Meir, Paola Porrati, Gaetano Finocchiaro, Maura Massimino, Carlos G Carlotti, Claudia C Faria, Martine F Roussel, Frederick Boop, Jennifer A Chan, Kimberly A Aldinger, Ferechte Razavi, Evelina Silvestri, Roger E McLendon, Eric Michael Thompson, Marc Ansari, Maria L Garre, Fernando Chico, Pilar Eguía, Mario Pérezpeña, A Sorana Morrissy, Florence M G Cavalli, Xiaochong Wu, Craig Daniels, Jeremy N Rich, Steven J M Jones, Richard A Moore, Marco A Marra, Xi Huang, Jüri Reimand, Poul H Sorensen, Robert J Wechsler-Reya, William A Weiss, Trevor J Pugh, Livia Garzia, Claudia L Kleinman, Lincoln D Stein, Nada Jabado, David Malkin, Olivier Ayrault, Jeffrey A Golden, David W Ellison, Bradley W Doble, Vijay Ramsawami, Tamra E Werbowetski-Ogilvie, Hiromichi Suzuki, Kathleen J Millen, Michael D Taylor
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature (2022)
Christopher D Steele, Ammal Abbasi, S M Ashiqul Islam, Amy L Bowes, Azhar Khandekar, Kerstin Haase, Shadi Hames-Fathi, Dolapo Ajayi, Annelien Verfaillie, Pawan Dhami, Alex McLatchie, Matt Lechner, Nicholas Light, Adam Shlien, David Malkin, Andrew Feber, Paula Z Proszek, Tom Lesluyes, Fredrik Mertens, Adrienne M Flanagan, Maxime Tarabichi, Peter Van Loo, Ludmil B Alexandrov, Nischalan Pillay
Signatures of copy number alterations in human cancer. Nature 606 (7916) (2022)
Anirban Das, Sumedha Sudhaman, Daniel A Morgenstern, Ailish Coblentz, Jiil Chung, Simone C Stone, Noor Said Alsafwani, Zhihui Amy Liu, Ola Abu Al Karsaneh, Shirin Soleimani, Hagay Ladany, David Chen, Matthew Zatzman, Vanja Cabric, Liana Nobre, Vanessa Bianchi, Melissa Edwards, Lauren C Sambira Nahum, Ayse Bahar Ercan, Arash Nabbi, Shlomi Constantini, Rina Dvir, Michal Yalon-Oren, Gadi Abebe Campino, Shani Caspi, Valerie Larouche, Alyssa Reddy, Michael Osborn, Gary Mason, Scott Lindhorst, Annika Bronsema, Magimairajan Issai Vanan, Enrico Opocher, Rebecca Loret De Mola, Magnus Sabel, Charlotta Frojd, David Sumerauer, David Samuel, Kristina Cole, Stefano Chiaravalli, Maura Massimino, Patrick Tomboc, David S Ziegler, Ben George, An Van Damme, Nobuko Hijiya, David Gass, Rose B McGee, Oz Mordechai, Daniel C Bowers, Theodore W Laetsch, Alexander Lossos, Deborah T Blumenthal, Tomasz Sarosiek, Lee Yi Yen, Jeffrey Knipstein, Anne E Bendel, Lindsey M Hoffman, Sandra Luna-Fineman, Stefanie Zimmermann, Isabelle Scheers, Kim E Nichols, Michal Zapotocky, Jordan R Hansford, John M Maris, Peter B Dirks, Michael D Taylor, Abhaya V Kulkarni, Manohar Shroff, Derek S Tsang, Anita Villani, Wei Xu, Melyssa Aronson, Carol Durno, Adam Shlien, David Malkin, Gad A Getz, Yosef E Maruvka, Pamela S Ohashi, Cynthia Hawkins, Trevor J Pugh, Eric Bouffet, Uri Tabori
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. Nature medicine 28 (1) (2022)
Jiil Chung, Logine Negm, Vanessa Bianchi, Lucie Stengs, Anirban Das, Zhihui Amy Liu, Sumedha Sudhaman, Melyssa Aronson, Ledia Brunga, Melissa Edwards, Victoria J Forster, Martin Komosa, Scott Davidson, Jodi Lees, Patrick Tomboc, David Samuel, Roula Farah, Anne Bendel, Jeffrey Knipstein, Kami Wolfe Schneider, Agnes Reschke, Shayna Zelcer, Alexandra Zorzi, Robert R McWilliams, William D Foulkes, Raymond Bedgood, Lindsay L Peterson, Sara Rhode, An Van Damme, Isabelle Scheers, Sharon Gardner, Gabriel Robbins, Magimairajan Issai Vanan, M Stephen Meyn, Rebecca A C Auer, Brandie H Leach, Carol Burke, Anita Villani, David Malkin, Eric Bouffet, Annie Huang, Michael D Taylor, Carol Durno, Adam Shlien, Cynthia Hawkins, Gad Getz, Yosef E Maruvka, Uri Tabori, null null
Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D Anderson, Arun K Ramani, Kyoko E Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D Wasserman, Rosemarie E Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A Whitlock, Stephen W Scherer, Kathy Chun, Martin J Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramsawami, Gino R Somers, Lianna Kyriakopoulou, Johann K Hitzler, Mary Shago, Daniel A Morgenstern, Uri Tabori, Stephen Meyn, Meredith S Irwin, David Malkin, Adam Shlien
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations. Nature cancer 4 (2) (2022)
Larissa Waldman, Kelly Hancock, Bailey Gallinger, Brittney Johnstone, Ledia Brunga, David Malkin, Maru Barrera, Anita Villani
Perspectives and Experiences of Parents and Adolescents Who Participate in a Pediatric Precision Oncology Program: "When You Feel Helpless, This Kind of Thing Is Very Helpful". JCO precision oncology 6 (2022)
Sarah Cohen-Gogo, Nisha Kanwar, Furqan Shaikh, Reto M Baertschiger, Adam Shlien, David Malkin, Juan Putra, Ailish C Coblentz, Anita Villani, Abha A Gupta, Daniel A Morgenstern
Response to Alpelisib in an Adolescent With PIK3CA -Mutated Metastatic Gastrointestinal Stromal Tumor. JCO precision oncology 6 (2022)
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D Anderson, Arun K Ramani, Kyoko E Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D Wasserman, Rosemarie E Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A Whitlock, Stephen W Scherer, Kathy Chun, Martin J Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramsawami, Gino R Somers, Lianna Kyriakopoulou, Johann K Hitzler, Mary Shago, Daniel A Morgenstern, Uri Tabori, Stephen Meyn, Meredith S Irwin, David Malkin, Adam Shlien
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations. Nature cancer 4 (2) (2022)
Suzanne P MacFarland, Luke D Maese, Surya P Rednam, Junne Kamihara, Melissa R Perrino, Kim E Nichols, Garrett M Brodeur, Joshua D Schiffman, Sharon E Plon, Lisa R Diller, David Malkin, Christopher C Porter, Anita Villani
Collaboration to Promote Research and Improve Clinical Care in the Evolving Field of Childhood Cancer Predisposition. Cancer prevention research (Philadelphia, Pa.) 15 (10) (2022)
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D Anderson, Arun K Ramani, Kyoko E Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D Wasserman, Rosemarie E Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A Whitlock, Stephen W Scherer, Kathy Chun, Martin J Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramsawami, Gino R Somers, Lianna Kyriakopoulou, Johann K Hitzler, Mary Shago, Daniel A Morgenstern, Uri Tabori, Stephen Meyn, Meredith S Irwin, David Malkin, Adam Shlien
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations. Nature cancer 4 (2) (2022)
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D Anderson, Arun K Ramani, Kyoko E Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D Wasserman, Rosemarie E Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A Whitlock, Stephen W Scherer, Kathy Chun, Martin J Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramsawami, Gino R Somers, Lianna Kyriakopoulou, Johann K Hitzler, Mary Shago, Daniel A Morgenstern, Uri Tabori, Stephen Meyn, Meredith S Irwin, David Malkin, Adam Shlien
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations. Nature cancer 4 (2) (2022)
Patryk Skowron, Hamza Farooq, Florence M G Cavalli, A Sorana Morrissy, Michelle Ly, Liam D Hendrikse, Evan Y Wang, Haig Hugo Vrej Djambazian, Helen Zhu, Karen L Mungall, Quang M Trinh, Tina Zheng, Shizhong Dai, Ana S Guerreiro Stucklin, Maria C Vladoiu, Vernon Fong, Borja L Holgado, Carolina Nor, Xiaochong Wu, Diala Abd-Rabbo, Pierre Bérubé, Yu Chang Wang, Betty Luu, Raul A Suarez, Avesta Rastan, Aaron H Gillmor, John J Y Lee, Xiao Yun Zhang, Craig Daniels, Peter B Dirks, David Malkin, Eric Bouffet, Uri Tabori, James Loukides, François P Doz, Franck Bourdeaut, Olivier O Delattre, Julien Masliah-Planchon, Olivier Ayrault, Seung-Ki Kim, David Meyronet, Wieslawa A Grajkowska, Carlos G Carlotti, Carmen de Torres, Jaume Mora, Charles G Eberhart, Erwin G Van Meir, Toshihiro Kumabe, Pim J French, Johan M Kros, Nada Jabado, Boleslaw Lach, Ian F Pollack, Ronald L Hamilton, Amulya A Nageswara Rao, Caterina Giannini, James M Olson, László Bognár, Almos Klekner, Karel Zitterbart, Joanna J Phillips, Reid C Thompson, Michael K Cooper, Joshua B Rubin, Linda M Liau, Miklós Garami, Peter Hauser, Kay Ka Wai Li, Ho-Keung Ng, Wai Sang Poon, G Yancey Gillespie, Jennifer A Chan, Shin Jung, Roger E McLendon, Eric M Thompson, David Zagzag, Rajeev Vibhakar, Young Shin Ra, Maria Luisa Garre, Ulrich Schüller, Tomoko Shofuda, Claudia C Faria, Enrique López-Aguilar, Gelareh Zadeh, Chi-Chung Hui, Vijay Ramsawami, Swneke D Bailey, Steven J M Jones, Andrew J Mungall, Richard A Moore, John A Calarco, Lincoln D Stein, Gary D Baider, Jüri Reimand, Jiannis Ragoussis, William A Weiss, Marco A Marra, Hiromichi Suzuki, Michael D Taylor
The transcriptional landscape of Shh medulloblastoma. Nature communications 12 (1) (2021)
Christian Peter Kratz, Anita Villani, Kim E Nichols, Joshua D Schiffman, David Malkin
Cancer surveillance for individuals with Li-Fraumeni syndrome. European journal of human genetics : EJHG 28 (11) (2020)
Valeria Capaci, Lorenzo Bascetta, Marco Fantuz, Galina V Beznoussenko, Roberta Sommaggio, Valeria Cancila, Andrea Bisso, Elena Campaner, Alexander A Mironov, Jacek R Wiśniewski, Luisa Ulloa Severino, Denis Scaini, Fleur Bossi, Jodi Lees, Noa Alon, Ledia Brunga, David Malkin, Silvano Piazza, Licio Collavin, Antonio Rosato, Silvio Bicciato, Claudio Tripodo, Fiamma Mantovani, Giannino Del Sal
Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome. Nature communications 11 (1) (2020)
Malgorzata Pienkowska, Sanaa Choufani, Andrei L Turinsky, Tanya Guha, Diana M Merino, Ana Novokmet, Michael Brudno, Rosanna Weksberg, Adam Shlien, Cynthia Hawkins, Eric Bouffet, Uri Tabori, Richard J Gilbertson, Jonathan L Finlay, Nada Jabado, Christian Thomas, Martin Sill, David Capper, Martin Hasselblatt, David Malkin
DNA methylation signature is prognostic of choroid plexus tumor aggressiveness. Clinical epigenetics 11 (1) (2019)
Catherine Goudie, Noelle Cullinan, Anita Villani, Natalie Mathews, Kalene van Engelen, David Malkin, Meredith S Irwin, William D Foulkes
Retrospective evaluation of a decision-support algorithm (MIPOGG) for genetic referrals for children with neuroblastic tumors. Pediatric blood & cancer 65 (12) (2018)
Evan Weber, Cheryl Shuman, Jonathan D Wasserman, Maru Barrera, Andrea F Patenaude, Karen Fung, David Chitayat, David Malkin, Harriet Druker
"A change in perspective": Exploring the experiences of adolescents with hereditary tumor predisposition. Pediatric blood & cancer 66 (1) (2018)
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Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors. Science (New York, N.Y.) 361 (6405) (2018)