Emilio Hirsch (E Hirsh)

ResearcherID Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 38

Top Venues

Nature communications

Arteriosclerosis, thrombosis, and vascular biology

Science translational medicine

Cardiovascular research

University of Torino

University of Torino (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Torino Jan 01 2005

Italy

Full Professor of Experimental Biology :: Biotecnologie Molecolari e Sciene della Salute

Education History

University of Torino

Italy

PHD

Publications

Nikoleta Pavlaki, Alexander Froese, Wener Li, Kirstie A De Jong, Birgit Geertz, Hariharan Subramanian, Sanika Mohagaonkar, Xiaojing Luo, Mario Schubert, Robert Wiegmann, Jean Piero Margaria, Alessandra Ghigo, Susanne Kämmerer, Emilio Hirsch, Ali El-Armouche, Kaomei Guan, Viacheslav O Nikolaev
Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation. Cardiovascular research (2024)
Emilio Hirsch, Emanuele Fantastico, Lorenzo Prever, Federico Gulluni
A connection between phosphatidylinositol 5-phosphate and the Hippo pathway to prevent epithelial-mesenchymal transition in cancer. Science signaling 17 (838) (2024)
Nikoleta Pavlaki, Alexander Froese, Wener Li, Kirstie A De Jong, Birgit Geertz, Hariharan Subramanian, Sanika Mohagaonkar, Xiaojing Luo, Mario Schubert, Robert Wiegmann, Jean Piero Margaria, Alessandra Ghigo, Susanne Kämmerer, Emilio Hirsch, Ali El-Armouche, Kaomei Guan, Viacheslav O Nikolaev
Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation. Cardiovascular research 120 (9) (2024)
Emilio Hirsch, Emanuele Fantastico, Lorenzo Prever, Federico Gulluni
A connection between phosphatidylinositol 5-phosphate and the Hippo pathway to prevent epithelial-mesenchymal transition in cancer. Science signaling 17 (838) (2024)
Mouin Nasr, Alexis Fay, Adrien Lupieri, Nicole Malet, Anne Darmon, Rana Zahreddine, Audrey Swiader, Amandine Wahart, Julien Viaud, Anne Nègre-Salvayre, Emilio Hirsch, Daniel Monteyne, David Perez-Morga, Nicolas Dupont, Patrice Codogno, Damien Ramel, Etienne Morel, Muriel Laffargue, Stéphanie Gayral
PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (3) (2023)
Mouin Nasr, Alexis Fay, Adrien Lupieri, Nicole Malet, Anne Darmon, Rana Zahreddine, Audrey Swiader, Amandine Wahart, Julien Viaud, Anne Nègre-Salvayre, Emilio Hirsch, Daniel Monteyne, David Perez-Morga, Nicolas Dupont, Patrice Codogno, Damien Ramel, Etienne Morel, Muriel Laffargue, Stéphanie Gayral
PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (3) (2023)
Cristina Mastini, Marco Campisi, Enrico Patrucco, Giulia Mura, Antonio P A Ferreira, Carlotta Costa, Chiara Ambrogio, Giulia Germena, Cinzia Martinengo, Silvia Peola, Ines Mota, Elena Vissio, Luca Molinaro, Maddalena Arigoni, Martina Olivero, Raffaele Calogero, Nina Prokoph, Fabrizio Tabbò, Brent Shoji, Laurence Brugieres, Didier Frappaz, Suzanne D Turner, Carlos Cuesta-Mateos, Deborah D'Aliberti, Luca Mologni, Rocco Giovanni Piazza, Carlo Gambacorti-Passerini, Giorgio G Inghirami, Valeria Chiono, Roger Dale Kamm, Emilio Hirsch, Raphael Koch, David M Weinstock, Jon C Aster, Claudia Voena, Roberto Chiarle
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma. Science translational medicine 15 (702) (2023)
Mouin Nasr, Alexis Fay, Adrien Lupieri, Nicole Malet, Anne Darmon, Rana Zahreddine, Audrey Swiader, Amandine Wahart, Julien Viaud, Anne Nègre-Salvayre, Emilio Hirsch, Daniel Monteyne, David Perez-Morga, Nicolas Dupont, Patrice Codogno, Damien Ramel, Etienne Morel, Muriel Laffargue, Stéphanie Gayral
PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (3) (2023)
Cristina Mastini, Marco Campisi, Enrico Patrucco, Giulia Mura, Antonio P A Ferreira, Carlotta Costa, Chiara Ambrogio, Giulia Germena, Cinzia Martinengo, Silvia Peola, Ines Mota, Elena Vissio, Luca Molinaro, Maddalena Arigoni, Martina Olivero, Raffaele Calogero, Nina Prokoph, Fabrizio Tabbò, Brent Shoji, Laurence Brugieres, Didier Frappaz, Suzanne D Turner, Carlos Cuesta-Mateos, Deborah D'Aliberti, Luca Mologni, Rocco Giovanni Piazza, Carlo Gambacorti-Passerini, Giorgio G Inghirami, Valeria Chiono, Roger Dale Kamm, Emilio Hirsch, Raphael Koch, David M Weinstock, Jon C Aster, Claudia Voena, Roberto Chiarle
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma. Science translational medicine 15 (702) (2023)
Mouin Nasr, Alexis Fay, Adrien Lupieri, Nicole Malet, Anne Darmon, Rana Zahreddine, Audrey Swiader, Amandine Wahart, Julien Viaud, Anne Nègre-Salvayre, Emilio Hirsch, Daniel Monteyne, David Perez-Morga, Nicolas Dupont, Patrice Codogno, Damien Ramel, Etienne Morel, Muriel Laffargue, Stéphanie Gayral
PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice. Arteriosclerosis, thrombosis, and vascular biology (2023)
Mouin Nasr, Alexis Fay, Adrien Lupieri, Nicole Malet, Anne Darmon, Rana Zahreddine, Audrey Swiader, Amandine Wahart, Julien Viaud, Anne Nègre-Salvayre, Emilio Hirsch, Daniel Monteyne, David Perez-Morga, Nicolas Dupont, Patrice Codogno, Damien Ramel, Etienne Morel, Muriel Laffargue, Stéphanie Gayral
PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (3) (2023)
Cristina Mastini, Marco Campisi, Enrico Patrucco, Giulia Mura, Antonio P A Ferreira, Carlotta Costa, Chiara Ambrogio, Giulia Germena, Cinzia Martinengo, Silvia Peola, Ines Mota, Elena Vissio, Luca Molinaro, Maddalena Arigoni, Martina Olivero, Raffaele Calogero, Nina Prokoph, Fabrizio Tabbò, Brent Shoji, Laurence Brugieres, Didier Frappaz, Suzanne D Turner, Carlos Cuesta-Mateos, Deborah D'Aliberti, Luca Mologni, Rocco Giovanni Piazza, Carlo Gambacorti-Passerini, Giorgio G Inghirami, Valeria Chiono, Roger Dale Kamm, Emilio Hirsch, Raphael Koch, David M Weinstock, Jon C Aster, Claudia Voena, Roberto Chiarle
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma. Science translational medicine 15 (702) (2023)
Luca Gozzelino, Gaga Kochlamazashvili, Sara Baldassari, Albert Ian Mackintosh, Laura Licchetta, Emanuela Iovino, Yu Chi Liu, Caitlin A Bennett, Mark F Bennett, John A Damiano, Gábor Zsurka, Caterina Marconi, Tania Giangregorio, Pamela Magini, Marijn Kuijpers, Tanja Maritzen, Giuseppe Danilo Norata, Stéphanie Baulac, Laura Canafoglia, Marco Seri, Paolo Tinuper, Ingrid E Scheffer, Melanie Bahlo, Samuel Frank Berkovic, Michael S Hildebrand, Wolfram S Kunz, Lucio Giordano, Francesca Bisulli, Miriam Martini, Volker Haucke, Emilio Hirsch, Tommaso Pippucci
Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy. Brain : a journal of neurology 145 (7) (2022)
Carlo Gabriele Tocchetti, Alessandra Ghigo, Emilio Hirsch
'Circulating' RNA-based therapies in Cardio-Oncology. European heart journal 43 (42) (2022)
Jean Piero Margaria, Lucia Moretta, José Carlos Alves Filho, Emilio Hirsch
PI3K Signaling in Mechanisms and Treatments of Pulmonary Fibrosis Following Sepsis and Acute Lung Injury. Biomedicines 10 (4) (2022)
Federica Barutta, Stefania Bellini, S Kimura, K Hase, B Corbetta, A Corbelli, F Fiordaliso, S Bruno, L Biancone, A Barreca, M G Papotti, Emilio Hirsch, Miriam Martini, R Gambino, M Durazzo, H Ohno, Gabriella Gruden
Protective effect of the tunneling nanotube-TNFAIP2/M-sec system on podocyte autophagy in diabetic nephropathy. Autophagy (2022)
Alessandra Ghigo, Alessandra Murabito, Valentina Sala, Anna Rita Pisano, Serena Bertolini, Ambra Gianotti, Emanuela Caci, Alessio Montresor, Aiswarya Premchandar, Flora Pirozzi, Kai Ren, Angela Della Sala, Marco Mergiotti, Wito Richter, Eyleen de Poel, Michaela Matthey, Sara Caldrer, Rosa A Cardone, Federica Civiletti, Andrea Costamagna, Nancy L Quinney, Cosmin Stefan Butnarasu, Sonja Visentin, Maria Rosaria Ruggiero, Simona Baroni, Simonetta Geninatti Crich, Damien Ramel, Muriel Laffargue, Carlo Gabriele Tocchetti, Renzo Levi, Marco Conti, Xiao-Yun Lu, Paola Melotti, Claudio Sorio, Virginia De Rose, Fabrizio Facchinetti, Vito Fanelli, Daniela Wenzel, Bernd K Fleischmann, Marcus Alexander Mall, Jeffrey M Beekman, Carlo Laudanna, Martina Gentzsch, Gergely László Lukács, Nicoletta Pedemonte, Emilio Hirsch
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases. Science translational medicine 14 (638) (2022)
Ramona Rotolo, Valeria Leuci, Chiara Donini, Federica Galvagno, Annamaria Massa, Maria Chiara De Santis, Serena Peirone, Giovanni Medico, Martina Sanlorenzo, Igor Vujic, Loretta Gammaitoni, Marco Basiricò, Luisella Righi, Chiara Riganti, Iris Chiara Salaroglio, Francesca Napoli, Fabrizio Tabbò, Annapaola Mariniello, Elisa Vigna, Chiara Modica, Lorenzo D'Ambrosio, Giovanni Grignani, Riccardo Taulli, Emilio Hirsch, Matteo Cereda, Massimo Aglietta, Giorgio Vittorio Scagliotti, Silvia Novello, Paolo Bironzo, Dario Sangiolo
Novel lymphocyte-independent antitumor activity by PD-1 blocking antibody against PD-1+ chemoresistant lung cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Federico Gulluni, Lorenzo Prever, Huayi Li, Petra Krafcikova, Ilaria Corrado, Wen-Ting Lo, Jean Piero Margaria, Anlu Chen, Maria Chiara De Santis, Sophie Julie A Cnudde, Joseph Fogerty, Alex Yuan, Alberto Massarotti, Nasrin Torabi Sarijalo, Oscar Vadas, Roger L Williams, Marcus Thelen, David R Powell, Markus Schueler, Michael S Wiesener, Tamas Balla, Hagit Baris Feldman, Dov Tiosano, Brian M McDermott, Brian D Perkins, Alessandra Ghigo, Miriam Martini, Volker Haucke, Evzen Boura, Giorgio Roberto Merlo, David A Buchner, Emilio Hirsch
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation. Science (New York, N.Y.) 374 (6573) (2021)
Celia Cintas, Thibault Douche, Zahra Dantes, Emmanuelle Mouton-Barbosa, Marie-Pierre Bousquet, Coralie Cayron, Nicole Therville, Frédéric Pont, Fernanda Ramos-Delgado, Camille Guyon, Barbara Garmy-Susini, Paola Cappello, Odile Burlet-Schiltz, Emilio Hirsch, Anne Gomez-Brouchet, Benoît Thibault, Maximilian Reichert, Julie Guillermet-Guibert
Phosphoproteomics Identifies PI3K Inhibitor-selective Adaptive Responses in Pancreatic Cancer Cell Therapy and Resistance. Molecular cancer therapeutics 20 (12) (2021)
Giovanni Nicolao Berta, Federica Di Scipio, Zhiqian Yang, Alessandra Oberto, Giuliana Abbadessa, Federica Romano, Maria Elisabetta Carere, Adriano Ceccarelli, Emilio Hirsch, Barbara Mognetti
Chemical Oral Cancerogenesis Is Impaired in PI3Kγ Knockout and Kinase-Dead Mice. Cancers 13 (16) (2021)
Paulin Brosinsky, Julia Bornbaum, Björn Warga, Lisa Schulz, Klaus-Dieter Schlüter, Alessandra Ghigo, Emilio Hirsch, Rainer Schulz, Gerhild Euler, Jacqueline Heger
PI3K as Mediator of Apoptosis and Contractile Dysfunction in TGFβ1-Stimulated Cardiomyocytes. Biology 10 (7) (2021)
Laura Seclì, Lidia Avalle, Pietro Poggio, Giuseppe Fragale, Cristiana Cannata, Laura Conti, Andrea Iannucci, Giovanna Carrà, Cristina Rubinetto, Barbara Miniscalco, Emilio Hirsch, Valeria Poli, Alessandro Morotti, Marco De Andrea, Emilia Turco, Federica Cavallo, Federica Fusella, Mara Brancaccio
Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity. Cancer research 81 (18) (2021)
Huayi Li, Lorenzo Prever, Emilio Hirsch, Federico Gulluni
Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer. Cancers 13 (14) (2021)
Asma Boukhalfa, Anna Chiara Nascimbeni, Damien Ramel, Nicolas Dupont, Emilio Hirsch, Stephanie Gayral, Muriel Laffargue, Patrice Codogno, Etienne Morel
PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nature communications 11 (1) (2020)
Mara Brancaccio, Flora Pirozzi, Emilio Hirsch, Alessandra Ghigo
Mechanisms underlying the cross-talk between heart and cancer. The Journal of physiology 598 (14) (2019)
Braulio Henrique Freire Lima, Pedro Elias Marques, Lindisley Ferreira Gomides, Matheus Silvério Mattos, Lucas Kraemer, Celso Martins Queiroz-Junior, Mark Lennon, Emilio Hirsch, Remo Castro Russo, Gustavo Batista Menezes, Edith M Hessel, Augustin Amour, Mauro Martins Texeira
Converging TLR9 and PI3Kgamma signaling induces sterile inflammation and organ damage. Scientific reports 9 (1) (2019)
Carolina Torres, Georgina Mancinelli, Jose Cordoba-Chacon, Navin Viswakarma, Karla Castellanos, Sam Grimaldo, Sandeep Kumar, Daniel Principe, Matthew J Dorman, Ronald McKinney, Emilio Hirsch, David Dawson, Hidayatullah G Munshi, Ajay Rana, Paul J Grippo
p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America 116 (29) (2019)
Maria C Silva, Marcela Davoli-Ferreira, Tiago S Medina, Renata Sesti-Costa, Grace K Silva, Carla D Lopes, Lucas E Cardozo, Fábio N Gava, Konstantina Lyroni, Fabrício C Dias, Amanda F Frade, Monique Baron, Helder Takashi Imoto Nakaya, Florêncio Figueiredo, José C Alves-Filho, Fernando Q Cunha, Christos Tsatsanis, Christophe Chevillard, Edécio Cunha-Neto, Emilio Hirsch, João S Silva, Thiago M Cunha
Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nature communications 9 (1) (2018)
Carlo Cosimo Campa, Jean Piero Margaria, Abhishek Derle, Marco Del Giudice, Maria Chiara De Santis, Luca Gozzelino, Francesca Copperi, Carla Bosia, Emilio Hirsch
Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes. Nature chemical biology 14 (8) (2018)
Matthew Movsesian, Faiyaz Ahmad, Emilio Hirsch
Functions of PDE3 Isoforms in Cardiac Muscle. Journal of cardiovascular development and disease 5 (1) (2018)
Meredith L Jenkins, Jean Piero Margaria, Jordan T B Stariha, Reece M Hoffmann, Jacob A McPhail, David J Hamelin, Martin J Boulanger, Emilio Hirsch, John E Burke
Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5. Nature communications 9 (1) (2018)
Valentina Zamboni, Maria Armentano, Gaia Berto, Elisa Ciraolo, Alessandra Ghigo, Donatella Garzotto, Alessandro Umbach, Ferdinando DiCunto, Elena Parmigiani, Marina Boido, Alessandro Vercelli, Nadia El-Assawy, Alessandro Mauro, Lorenzo Priano, Luisa Ponzoni, Luca Murru, Maria Passafaro, Emilio Hirsch, Giorgio R Merlo
Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics. Scientific reports 8 (1) (2018)
Valentina Zamboni, Rebecca Jones, Alessandro Umbach, Alessandra Ammoni, Maria Passafaro, Emilio Hirsch, Giorgio R Merlo
Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities. International journal of molecular sciences 19 (6) (2018)
Elisabeth Wyart, Simone Reano, Myriam Y Hsu, Dario Livio Longo, Mingchuan Li, Emilio Hirsch, Nicoletta Filigheddu, Alessandra Ghigo, Chiara Riganti, Paolo Ettore Porporato
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting. Oxidative medicine and cellular longevity 2018 (2018)
Carlo C Campa, Rangel L Silva, Jean P Margaria, Tracey Pirali, Matheus S Mattos, Lucas R Kraemer, Diego C Reis, Giorgio Grosa, Francesca Copperi, Eduardo M Dalmarco, Roberto C P Lima-Júnior, Silvio Aprile, Valentina Sala, Federica Dal Bello, Douglas Silva Prado, José Carlos Alves Filho, Claudio Medana, Geovanni D Cassali, Gian Cesare Tron, Mauro M Teixeira, Elisa Ciraolo, Remo C Russo, Emilio Hirsch
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis. Nature communications 9 (1) (2018)
Federico Gulluni, Miriam Martini, Emilio Hirsch
Cytokinetic Abscission: Phosphoinositides and ESCRTs Direct the Final Cut. Journal of cellular biochemistry 118 (11) (2017)
Sebastian R Nielsen, Valeria Quaranta, Andrea Linford, Perpetua Emeagi, Carolyn Rainer, Almudena Santos, Lucy Ireland, Takao Sakai, Keiko Sakai, Yong-Sam Kim, Dannielle D Engle, Fiona Campbell, Daniel Palmer, Jeong Heon Ko, David A Tuveson, Emilio Hirsch, Ainhoa Mielgo, Michael C Schmid
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis. Nature cell biology 18 (5) (2016)
Laura Braccini, Elisa Ciraolo, Carlo C Campa, Alessia Perino, Dario L Longo, Gianpaolo Tibolla, Marco Pregnolato, Yanyan Cao, Beatrice Tassone, Federico Damilano, Muriel Laffargue, Enzo Calautti, Marco Falasca, Giuseppe D Norata, Jonathan M Backer, Emilio Hirsch
PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nature communications 6 (2015)

Emilio Hirsch.css-eqlu8i{font-size:small;padding-left:4px;} (E Hirsh)

Publication Activity (10 Years)

Top Topics

Top Venues

Emilio Hirsch (E Hirsh)