Wolf-Dietrich Hardt

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 41

Top Venues

Nature microbiology

PLoS biology

eLife

Proceedings of the National Academy of Sciences of the United States of America

Eidgenössische Technische Hochschule Zürich

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Eidgenössische Technische Hochschule Zürich

Switzerland

Professor of Microbiology :: D-BIOL

Publications

Chantal Ernst, Patrick R Andreassen, Gabriel H Giger, Bidong D Nguyen, Christoph G Gäbelein, Orane Guillaume-Gentil, Stefan A Fattinger, Mikael E Sellin, Wolf-Dietrich Hardt, Julia A Vorholt
Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution. PLoS biology 22 (4) (2024)
Chantal Ernst, Patrick R Andreassen, Gabriel H Giger, Bidong D Nguyen, Christoph G Gäbelein, Orane Guillaume-Gentil, Stefan A Fattinger, Mikael E Sellin, Wolf-Dietrich Hardt, Julia A Vorholt
Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution. PLoS biology 22 (4) (2024)
Yassine Cherrak, Miguel Angel Salazar, Koray Yilmaz, Markus Kreuzer, Wolf-Dietrich Hardt
Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner. PLoS biology 22 (6) (2024)
Yassine Cherrak, Miguel Angel Salazar, Koray Yilmaz, Markus Kreuzer, Wolf-Dietrich Hardt
Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner. PLoS biology 22 (6) (2024)
Yassine Cherrak, Miguel Angel Salazar, Koray Yilmaz, Markus Kreuzer, Wolf-Dietrich Hardt
Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner. PLoS biology 22 (6) (2024)
Yassine Cherrak, Miguel Angel Salazar, Nicolas Näpflin, Lukas Malfertheiner, Mathias K-M Herzog, Christopher Schubert, Christian von Mering, Wolf-Dietrich Hardt
Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut. Nature microbiology (2024)
Leanid Laganenka, Jae-Woo Lee, Lukas Malfertheiner, Cora Lisbeth Dieterich, Lea Fuchs, Jörn Piel, Christian von Mering, Victor Sourjik, Wolf-Dietrich Hardt
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature microbiology 8 (2) (2023)
Daniel Hoces, Giorgia Greter, Markus Arnoldini, Melanie L Stäubli, Claudia Moresi, Anna Sintsova, Sara Berent, Isabel Kolinko, Florence Bansept, Aurore Woller, Janine Häfliger, Eric Martens, Wolf-Dietrich Hardt, Shinichi Sunagawa, Claude Loverdo, Emma M C Slack
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota. eLife 12 (2023)
Leanid Laganenka, Jae-Woo Lee, Lukas Malfertheiner, Cora Lisbeth Dieterich, Lea Fuchs, Jörn Piel, Christian von Mering, Victor Sourjik, Wolf-Dietrich Hardt
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature microbiology 8 (2) (2023)
Leanid Laganenka, Jae-Woo Lee, Lukas Malfertheiner, Cora Lisbeth Dieterich, Lea Fuchs, Jörn Piel, Christian von Mering, Victor Sourjik, Wolf-Dietrich Hardt
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature microbiology (2023)
Ersin Gül, Erik Bakkeren, Guillem Salazar, Yves Steiger, Andrew Abi Younes, Melanie Clerc, Philipp Christen, Stefan A Fattinger, Bidong D Nguyen, Patrick Kiefer, Emma Slack, Martin Ackermann, Julia A Vorholt, Shinichi Sunagawa, Médéric Diard, Wolf-Dietrich Hardt
The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence. PLoS biology 21 (8) (2023)
Leanid Laganenka, Jae-Woo Lee, Lukas Malfertheiner, Cora Lisbeth Dieterich, Lea Fuchs, Jörn Piel, Christian von Mering, Victor Sourjik, Wolf-Dietrich Hardt
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature microbiology 8 (2) (2023)
Daniel Hoces, Giorgia Greter, Markus Arnoldini, Melanie L Stäubli, Claudia Moresi, Anna Sintsova, Sara Berent, Isabel Kolinko, Florence Bansept, Aurore Woller, Janine Häfliger, Eric Martens, Wolf-Dietrich Hardt, Shinichi Sunagawa, Claude Loverdo, Emma M C Slack
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota. eLife 12 (2023)
Daniel Hoces, Giorgia Greter, Markus Arnoldini, Melanie L Stäubli, Claudia Moresi, Anna Sintsova, Sara Berent, Isabel Kolinko, Florence Bansept, Aurore Woller, Janine Häfliger, Eric Martens, Wolf-Dietrich Hardt, Shinichi Sunagawa, Claude Loverdo, Emma M C Slack
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota. eLife 12 (2023)
Leanid Laganenka, Jae-Woo Lee, Lukas Malfertheiner, Cora Lisbeth Dieterich, Lea Fuchs, Jörn Piel, Christian von Mering, Victor Sourjik, Wolf-Dietrich Hardt
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature microbiology 8 (2) (2023)
Stefan Alexander Fattinger, Luca Maurer, Petra Geiser, Elliott M Bernard, Ursina Enz, Suwannee Ganguillet, Ersin Gül, Sanne Kroon, Benjamin Demarco, Vanessa Mack, Markus Furter, Manja Barthel, Pawel Pelczar, Feng Shao, Petr Broz, Mikael Erik Sellin, Wolf-Dietrich Hardt
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice. Proceedings of the National Academy of Sciences of the United States of America 120 (48) (2023)
Daniel Hoces, Giorgia Greter, Markus Arnoldini, Melanie L Stäubli, Claudia Moresi, Anna Sintsova, Sara Berent, Isabel Kolinko, Florence Bansept, Aurore Woller, Janine Häfliger, Eric Martens, Wolf-Dietrich Hardt, Shinichi Sunagawa, Claude Loverdo, Emma M C Slack
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota. eLife 12 (2023)
Ersin Gül, Ursina Enz, Luca Maurer, Andrew Abi Younes, Stefan A Fattinger, Bidong D Nguyen, Annika Hausmann, Markus Furter, Manja Barthel, Mikael E Sellin, Wolf-Dietrich Hardt
Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection. PLoS pathogens 19 (6) (2023)
Leanid Laganenka, Jae-Woo Lee, Lukas Malfertheiner, Cora Lisbeth Dieterich, Lea Fuchs, Jörn Piel, Christian von Mering, Victor Sourjik, Wolf-Dietrich Hardt
Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature microbiology (2023)
Sebastian Dan Burz, Senka Causevic, Alma Dal Co, Marija Dmitrijeva, Philipp Engel, Daniel Garrido-Sanz, Gilbert Greub, Siegfried Hapfelmeier, Wolf-Dietrich Hardt, Vassily Hatzimanikatis, Clara Margot Heiman, Mathias Klaus-Maria Herzog, Alyson Hockenberry, Christoph Keel, Andreas Keppler, Soon-Jae Lee, Julien Luneau, Lukas Malfertheiner, Sara Mitri, Bidong Ngyuen, Omid Oftadeh, Alan R Pacheco, François J Peaudecerf, Grégory Resch, Hans-Joachim Ruscheweyh, Asli Sahin, Ian R Sanders, Emma Slack, Shinichi Sunagawa, Janko Tackmann, Robin Tecon, Giovanni Stefano Ugolini, Jordan Vacheron, Jan Roelof Van der Meer, Evangelia Vayena, Pascale Vonaesch, Julia A Vorholt
From microbiome composition to functional engineering, one step at a time. Microbiology and molecular biology reviews : MMBR (2023)
Viktor Ek, Stefan Alexander Fattinger, Alexandra Florbrant, Wolf-Dietrich Hardt, Maria Letizia Di Martino, Jens Eriksson, Mikael Erik Sellin
A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface. Molecular microbiology 117 (5) (2022)
Rahel C Gerosa, Steffen Boettcher, Larisa V Kovtonyuk, Annika Hausmann, Wolf-Dietrich Hardt, Juan Hidalgo, César Nombela-Arrieta, Markus G Manz
CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis. Blood advances 5 (23) (2022)
Amit Gutwillig, Nadine Santana-Magal, Leen Farhat-Younis, Diana Rasoulouniriana, Asaf Madi, Chen Luxenburg, Jonathan Cohen, Krishnanand Padmanabhan, Noam Shomron, Guy Shapira, Annette Gleiberman, Roma Parikh, Carmit Levy, Meora Feinmesser, Dov Hershkovitz, Valentina Zemser-Werner, Oran Zlotnik, Sanne Kroon, Wolf-Dietrich Hardt, Reno Debets, Nathan Edward Reticker-Flynn, Peleg Rider, Yaron Carmi
Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy. eLife 11 (2022)
Daniel Hoces, Jiayi Lan, Wenfei Sun, Tobias Geiser, Melanie L Stäubli, Elisa Cappio Barazzone, Martin Ackermann, Tenagne D Challa, Manuel Klug, Alexandra Kellenberger, Sven Nowok, Erica Faccin, Andrew J Macpherson, Bärbel Stecher, Shinichi Sunagawa, Renato Zenobi, Wolf-Dietrich Hardt, Christian Wolfrum, Emma M C Slack
Metabolic reconstitution of germ-free mice by a gnotobiotic microbiota varies over the circadian cycle. PLoS biology 20 (9) (2022)
Erik Bakkeren, Ersin Gül, Jana Sanne Huisman, Yves Steiger, Andrea Rocker, Wolf-Dietrich Hardt, Médéric Diard
Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium. Nature communications 13 (1) (2022)
Erik Bakkeren, Joshua Patrick Mark Newson, Wolf-Dietrich Hardt
Analysis of Salmonella Persister Population Sizes, Dynamics of Gut Luminal Seeding, and Plasmid Transfer in Mouse Models of Salmonellosis. Methods in molecular biology (Clifton, N.J.) 2357 (2022)
Erik Bakkeren, Joana Anuschka Herter, Jana Sanne Huisman, Yves Steiger, Ersin Gül, Joshua Patrick Mark Newson, Alexander Oliver Brachmann, Jörn Piel, Roland R Regoes, Sebastian Bonhoeffer, Médéric Diard, Wolf-Dietrich Hardt
Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut. eLife 10 (2021)
Stefan Alexander Fattinger, Petra Geiser, Pilar Samperio Ventayol, Maria Letizia Di Martino, Markus Furter, Boas Felmy, Erik Bakkeren, Annika Hausmann, Manja Barthel-Scherrer, Ersin Gül, Wolf-Dietrich Hardt, Mikael Erik Sellin
Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice. Mucosal immunology 14 (3) (2021)
Algera Goga, Büsra Yagabasan, Karolin Herrmanns, Svenja Godbersen, Pamuditha N Silva, Remy Denzler, Mirjam Zünd, Markus Furter, Gerald Schwank, Shinichi Sunagawa, Wolf-Dietrich Hardt, Markus Stoffel
miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine. Nature communications 12 (1) (2021)
Alyson M Hockenberry, Gabriele Micali, Gabriella Takács, Jessica Weng, Wolf-Dietrich Hardt, Martin Ackermann
Microbiota-derived metabolites inhibit Salmonella virulent subpopulation development by acting on single-cell behaviors. Proceedings of the National Academy of Sciences of the United States of America 118 (31) (2021)
Médéric Diard, Erik Bakkeren, Verena Lentsch, Andrea Rocker, Nahimi Amare Bekele, Daniel Hoces, Selma Aslani, Markus Arnoldini, Flurina Böhi, Kathrin Schumann-Moor, Jozef Adamcik, Luca Piccoli, Antonio Lanzavecchia, Beth M Stadtmueller, Nicholas Donohue, Marjan W Van der Woude, Alyson Hockenberry, Patrick H Viollier, Laurent Falquet, Daniel Wüthrich, Ferdinando Bonfiglio, Claude Loverdo, Adrian Egli, Giorgia Zandomeneghi, Raffaele Mezzenga, Otto Holst, Beat H Meier, Wolf-Dietrich Hardt, Emma M C Slack
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants. Nature microbiology 6 (7) (2021)
Annika Hausmann, Boas Felmy, Leo Kunz, Sanne Kroon, Dorothée Lisa Berthold, Giverny Ganz, Ioana Sandu, Toshihiro Nakamura, Nathan Sébastien Zangger, Yang Zhang, Tamas Dolowschiak, Stefan Alexander Fattinger, Markus Furter, Anna Angelika Müller-Hauser, Manja Barthel, Katerina Vlantis, Laurens Wachsmuth, Jan Kisielow, Luigi Tortola, Danijela Heide, Mathias F Heikenwälder, Annette Oxenius, Manfred Kopf, Timm Schroeder, Manolis Pasparakis, Mikael Erik Sellin, Wolf-Dietrich Hardt
Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF. The Journal of experimental medicine 218 (11) (2021)
Pilar Samperio Ventayol, Petra Geiser, Maria Letizia Di Martino, Alexandra Florbrant, Stefan Alexander Fattinger, Naemi Walder, Eduardo Sima, Feng Shao, Nelson O Gekara, Magnus Sundbom, Wolf-Dietrich Hardt, Dominic-Luc Webb, Per M Hellström, Jens Eriksson, Mikael Erik Sellin
Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers. Proceedings of the National Academy of Sciences of the United States of America 118 (16) (2021)
Joel Selkrig, Nan Li, Annika Hausmann, Matthew S J Mangan, Matylda Zietek, André Mateus, Jacob Bobonis, Anna Sueki, Haruna Imamura, Bachir El Debs, Gianluca Sigismondo, Bogdan I Florea, Herman S Overkleeft, Nataša Kopitar-Jerala, Boris Turk, Pedro Beltrao, Mikhail M Savitski, Eicke Latz, Wolf-Dietrich Hardt, Jeroen Krijgsveld, Athanasios Typas
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. Nature microbiology 5 (9) (2020)
Stefan A Fattinger, Désirée Böck, Maria Letizia Di Martino, Sabrina Deuring, Pilar Samperio Ventayol, Viktor Ek, Markus Furter, Saskia Kreibich, Francesco Bosia, Anna Angelika Müller-Hauser, Bidong D Nguyen, Manfred Rohde, Martin Pilhofer, Wolf-Dietrich Hardt, Mikael Erik Sellin
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium. PLoS pathogens 16 (5) (2020)
Erik Bakkeren, Médéric Diard, Wolf-Dietrich Hardt
Evolutionary causes and consequences of bacterial antibiotic persistence. Nature reviews. Microbiology 18 (9) (2020)
Annika Hausmann, Wolf-Dietrich Hardt
Elucidating host-microbe interactions in vivo by studying population dynamics using neutral genetic tags. Immunology 162 (4) (2020)
Annika Hausmann, Giancarlo Russo, Jonas Grossmann, Mirjam Zünd, Gerald Schwank, Ruedi Aebersold, Yansheng Liu, Mikael Erik Sellin, Wolf-Dietrich Hardt
Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes. Cellular microbiology 22 (6) (2020)
Fabienne Benz, Jana Sanne Huisman, Erik Bakkeren, Joana A Herter, Tanja Stadler, Martin Ackermann, Médéric Diard, Adrian Egli, Alex R Hall, Wolf-Dietrich Hardt, Sebastian Bonhoeffer
Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo. The ISME journal 15 (3) (2020)
Sandra Y Wotzka, Markus Kreuzer, Lisa Maier, Markus Arnoldini, Bidong D Nguyen, Alexander O Brachmann, Dorothée Lisa Berthold, Mirjam Zünd, Annika Hausmann, Erik Bakkeren, Daniel Hoces, Ersin Gül, Markus Beutler, Tamas Dolowschiak, Michael Zimmermann, Tobias Fuhrer, Kathrin Moor, Uwe Sauer, Athanasios Typas, Jörn Piel, Médéric Diard, Andrew J Macpherson, Bärbel Stecher, Shinichi Sunagawa, Emma Slack, Wolf-Dietrich Hardt
Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice. Nature microbiology 4 (12) (2019)
Médéric Diard, Erik Bakkeren, Jeffrey K Cornuault, Kathrin Moor, Annika Hausmann, Mikael E Sellin, Claude Loverdo, Abram Aertsen, Martin Ackermann, Marianne De Paepe, Emma M C Slack, Wolf-Dietrich Hardt
Inflammation boosts bacteriophage transfer between Salmonella spp. Science (New York, N.Y.) 355 (6330) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Wolf-Dietrich Hardt