Ken Chen

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 98

Top Topics

Acute Myeloid Leukemia

Venous Thromboembolism

Positive Breast Cancer

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Nature medicine

Communications biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jia Wu, Muhammad Aminu, Lingzhi Hong, Natalie I Vokes, Stephanie Tzouanas Schmidt, Maliazurina B Saad, Bo Zhu, Xiuning Li, Cascone Tina, Ajay Sheshadri, David Jaffray, P Andrew Futreal, Jiun-Kae Jack Lee, Lauren Averett Byers, Don L Gibbons, John Victor Heymach, Ken Chen, Chao Cheng, Jianjun Zhang, Bo Wang
Joint multi-omics discriminant analysis with consistent representation learning using PANDA. Research square (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine 30 (3) (2024)
Sunita Keshari, Alexander S Shavkunov, Qi Miao, Akata Saha, Charmelle D Williams, Anna M Highsmith, Josué E Pineda, Elise Alspach, Kenneth H Hu, Kristen E Pauken, Ken Chen, Matthew M Gubin
Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy. bioRxiv : the preprint server for biology (2024)
Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal, Ken Chen
Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data. Communications biology 7 (1) (2024)
Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal, Ken Chen
Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data. Communications biology 7 (1) (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal, Ken Chen
Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data. Communications biology 7 (1) (2024)
Sarina A Piha-Paul, Chieh Tseng, Cheuk Hong Leung, Ying Yuan, Daniel D Karp, Vivek Subbiah, David Hong, Siqing Fu, Aung Naing, Jordi Rodon, Milind Javle, Jaffer A Ajani, Kanwal P S Raghav, Neeta Somaiah, Gordon B Mills, Apostolia-Maria Tsimberidou, Xiaofeng Zheng, Ken Chen, Funda Meric-Bernstam
Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations. NPJ precision oncology 8 (1) (2024)
Qingnan Liang, Luisa Solis Soto, Cara Haymaker, Ken Chen
Interpretable Spatial Gradient Analysis for Spatial Transcriptomics Data. bioRxiv : the preprint server for biology (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine 30 (3) (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine (2024)
Jonathan Goldberg, Na Qiao, Jennifer L Guerriero, Brett Gross, Yagiz Meneksedag, Yoshimi F Lu, Anne V Philips, Tasnim Rahman, Funda Meric-Bernstam, Jason Roszik, Ken Chen, Rinath M Jeselsohn, Sara M Tolaney, George E Peoples, Gheath Al-Atrash, Elizabeth A Mittendorf
Estrogen Receptor Mutations as Novel Targets for Immunotherapy in Metastatic Estrogen Receptor-Positive Breast Cancer. Cancer research communications (2024)
Sunita Keshari, Alexander S Shavkunov, Qi Miao, Akata Saha, Charmelle D Williams, Anna M Highsmith, Josué E Pineda, Elise Alspach, Kenneth H Hu, Kristen E Pauken, Ken Chen, Matthew M Gubin
Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy. bioRxiv : the preprint server for biology (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Sunil Acharya, Rafet Basar, May Daher, Hind Rafei, Ping Li, Nadima Uprety, Emily Ensley, Mayra Shanley, Bijender Kumar, Pinaki P Banerjee, Luciana Melo Garcia, Paul Lin, Vakul Mohanty, Kun Hee Kim, Xian-Li Jiang, Yuchen Pan, Ye Li, Bin Liu, Ana Karen Nunez Cortes, Chenyu Zhang, Mohsen Fathi, Ali Rezvan, Melisa J Montalvo, Sophia L Cha, Francia Reyes-Silva, Rejeena Shrestha, Xingliang Guo, Kiran Kundu, Alexander Biederstädt, Luis Muniz-Feliciano, Gary M Deyter, Mecit Kaplan, Xin Ru Jiang, Enli Liu, Antrix Jain, Jason Roszik, Natalie Wall Fowlkes, Luisa Maren Solis Soto, Maria Gabriela Raso, Joseph D Khoury, Pei Lin, Francisco Vega, Navin Varadarajan, Ken Chen, David Marin, Elizabeth J Shpall, Katayoun Rezvani
CD28 costimulation augments CAR signaling in NK cells via the LCK/CD3Z/ZAP70 signaling axis. Cancer discovery (2024)
Shan He, Matthew M Gubin, Hind Rafei, Rafet Basar, Merve Dede, Xianli Jiang, Qingnan Liang, Yukun Tan, Kunhee Kim, Maura L Gillison, Katayoun Rezvani, Weiyi Peng, Cara Haymaker, Sharia Hernandez, Luisa M Solis, Vakul Mohanty, Ken Chen
Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profiles. bioRxiv : the preprint server for biology (2024)
Sunil Acharya, Rafet Basar, May Daher, Hind Rafei, Ping Li, Nadima Uprety, Emily Ensley, Mayra Shanley, Bijender Kumar, Pinaki P Banerjee, Luciana Melo Garcia, Paul Lin, Vakul Mohanty, Kun Hee Kim, Xian-Li Jiang, Yuchen Pan, Ye Li, Bin Liu, Ana Karen Nunez Cortes, Chenyu Zhang, Mohsen Fathi, Ali Rezvan, Melisa J Montalvo, Sophia L Cha, Francia Reyes-Silva, Rejeena Shrestha, Xingliang Guo, Kiran Kundu, Alexander Biederstädt, Luis Muniz-Feliciano, Gary M Deyter, Mecit Kaplan, Xin Ru Jiang, Enli Liu, Antrix Jain, Jason Roszik, Natalie Wall Fowlkes, Luisa Maren Solis Soto, Maria Gabriela Raso, Joseph D Khoury, Pei Lin, Francisco Vega, Navin Varadarajan, Ken Chen, David Marin, Elizabeth J Shpall, Katayoun Rezvani
CD28 costimulation augments CAR signaling in NK cells via the LCK/CD3Z/ZAP70 signaling axis. Cancer discovery (2024)
Ye Li, Rafet Basar, Guohui Wang, Enli Liu, Judy S Moyes, Li Li, Lucila N Kerbauy, Nadima Uprety, Mohsen Fathi, Ali Rezvan, Pinaki P Banerjee, Luis Muniz-Feliciano, Tamara J Laskowski, Emily Ensley, May Daher, Mayra Shanley, Mayela Mendt, Sunil Acharya, Bin Liu, Alexander Biederstädt, Hind Rafei, Xingliang Guo, Luciana Melo Garcia, Paul Lin, Sonny Ang, David Marin, Ken Chen, Laura Bover, Richard E Champlin, Navin Varadarajan, Elizabeth J Shpall, Katayoun Rezvani
Author Correction: KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape. Nature medicine (2024)
Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal, Ken Chen
Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data. Communications biology 7 (1) (2024)
Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal, Ken Chen
Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data. Communications biology 7 (1) (2024)
Sunita Keshari, Alexander S Shavkunov, Qi Miao, Akata Saha, Charmelle D Williams, Anna M Highsmith, Josué E Pineda, Elise Alspach, Kenneth H Hu, Kristen E Pauken, Ken Chen, Matthew M Gubin
Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy. bioRxiv : the preprint server for biology (2024)
Qingnan Liang, Luisa Solis Soto, Cara Haymaker, Ken Chen
Interpretable Spatial Gradient Analysis for Spatial Transcriptomics Data. bioRxiv : the preprint server for biology (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Sarina A Piha-Paul, Chieh Tseng, Cheuk Hong Leung, Ying Yuan, Daniel D Karp, Vivek Subbiah, David Hong, Siqing Fu, Aung Naing, Jordi Rodon, Milind Javle, Jaffer A Ajani, Kanwal P S Raghav, Neeta Somaiah, Gordon B Mills, Apostolia-Maria Tsimberidou, Xiaofeng Zheng, Ken Chen, Funda Meric-Bernstam
Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations. NPJ precision oncology 8 (1) (2024)
Bijender Kumar, Anand Kamal Singh, Rafet Basar, Nadima Uprety, Ye Li, Huihui Fan, Ana Karen Nunez Cortes, Mecit Kaplan, Sunil Acharya, Hila Shaim, Anna C Xu, Manrong Wu, Emily Ensley, Dexing Fang, Pinaki P Banerjee, Luciana Melo Garcia, Silvia Tiberti, Paul Lin, Hind Rafei, Maliha Nuzhat Munir, Madison Moore, Mayra Shanley, Mayela Mendt, Lucila N Kerbauy, Bin Liu, Alexander Biederstädt, Elif Gokdemir, Susmita Ghosh, Kiran Kundu, Francia Reyes-Silva, Xin Ru Jiang, Xinhai Wan, April L Gilbert, Merve Dede, Vakul Mohanty, Jinzhuang Dou, Patrick Zhang, Enli Liu, Luis Muniz-Feliciano, Gary M Deyter, Abhinav K Jain, Juan José Rodríguez Sevilla, Simona Colla, Guillermo Garcia Manero, Elizabeth J Shpall, Ken Chen, Hussein A Abbas, Kunal Rai, Katayoun Rezvani, May Daher
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. Science translational medicine 16 (764) (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Sarina A Piha-Paul, Chieh Tseng, Cheuk Hong Leung, Ying Yuan, Daniel D Karp, Vivek Subbiah, David Hong, Siqing Fu, Aung Naing, Jordi Rodon, Milind Javle, Jaffer A Ajani, Kanwal P S Raghav, Neeta Somaiah, Gordon B Mills, Apostolia-Maria Tsimberidou, Xiaofeng Zheng, Ken Chen, Funda Meric-Bernstam
Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations. NPJ precision oncology 8 (1) (2024)
Jonathan Goldberg, Na Qiao, Jennifer L Guerriero, Brett Gross, Yagiz Meneksedag, Yoshimi F Lu, Anne V Philips, Tasnim Rahman, Funda Meric-Bernstam, Jason Roszik, Ken Chen, Rinath M Jeselsohn, Sara M Tolaney, George E Peoples, Gheath Al-Atrash, Elizabeth A Mittendorf
Estrogen Receptor Mutations as Novel Targets for Immunotherapy in Metastatic Estrogen Receptor-positive Breast Cancer. Cancer research communications 4 (2) (2024)
Jonathan Goldberg, Na Qiao, Jennifer L Guerriero, Brett Gross, Yagiz Meneksedag, Yoshimi F Lu, Anne V Philips, Tasnim Rahman, Funda Meric-Bernstam, Jason Roszik, Ken Chen, Rinath M Jeselsohn, Sara M Tolaney, George E Peoples, Gheath Al-Atrash, Elizabeth A Mittendorf
Estrogen Receptor Mutations as Novel Targets for Immunotherapy in Metastatic Estrogen Receptor-positive Breast Cancer. Cancer research communications 4 (2) (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine (2024)
Shan He, Matthew M Gubin, Hind Rafei, Rafet Basar, Merve Dede, Xianli Jiang, Qingnan Liang, Yukun Tan, Kunhee Kim, Maura L Gillison, Katayoun Rezvani, Weiyi Peng, Cara Haymaker, Sharia Hernandez, Luisa M Solis, Vakul Mohanty, Ken Chen
Elucidating immune-related gene transcriptional programs via factorization of large-scale RNA-profiles. bioRxiv : the preprint server for biology (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine 30 (3) (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine 30 (3) (2024)
Jonathan Goldberg, Na Qiao, Jennifer L Guerriero, Brett Gross, Yagiz Meneksedag, Yoshimi F Lu, Anne V Philips, Tasnim Rahman, Funda Meric-Bernstam, Jason Roszik, Ken Chen, Rinath M Jeselsohn, Sara M Tolaney, George E Peoples, Gheath Al-Atrash, Elizabeth A Mittendorf
Estrogen Receptor Mutations as Novel Targets for Immunotherapy in Metastatic Estrogen Receptor-positive Breast Cancer. Cancer research communications 4 (2) (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine 30 (3) (2024)
Muhammad Aminu, Lingzhi Hong, Natalie I Vokes, Stephanie Tzouanas Schmidt, Maliazurina Saad, Bo Zhu, Xiuning Li, Cascone Tina, Ajay Sheshadri, Bo Wang, David Jaffray, P Andrew Futreal, Jiun-Kae Jack Lee, Lauren Averett Byers, Don L Gibbons, John Victor Heymach, Ken Chen, Chao Cheng, Jianjun Zhang, Jia Wu
Joint multi-omics discriminant analysis with consistent representation learning using PANDA. Research square (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
David Marin, Ye Li, Rafet Basar, Hind Rafei, May Daher, Jinzhuang Dou, Vakul Mohanty, Merve Dede, Yago Nieto, Nadima Uprety, Sunil Acharya, Enli Liu, Jeffrey Wilson, Pinaki Banerjee, Homer A Macapinlac, Christina Ganesh, Peter F Thall, Roland L Bassett, Mariam Ammari, Sheetal Rao, Kai Cao, Mayra Shanley, Mecit Kaplan, Chitra Hosing, Partow Kebriaei, Loretta J Nastoupil, Christopher R Flowers, Sadie Mae Moseley, Paul Lin, Sonny Ang, Uday R Popat, Muzaffar H Qazilbash, Richard E Champlin, Ken Chen, Elizabeth J Shpall, Katayoun Rezvani
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 + B cell tumors: a phase 1/2 trial. Nature medicine (2024)
Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal, Ken Chen
Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data. Communications biology 7 (1) (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Sunil Acharya, Rafet Basar, May Daher, Hind Rafei, Ping Li, Nadima Uprety, Emily Ensley, Mayra Shanley, Bijender Kumar, Pinaki P Banerjee, Luciana Melo Garcia, Paul Lin, Vakul Mohanty, Kun Hee Kim, Xian-Li Jiang, Yuchen Pan, Ye Li, Bin Liu, Ana Karen Nunez Cortes, Chenyu Zhang, Mohsen Fathi, Ali Rezvan, Melisa J Montalvo, Sophia L Cha, Francia Reyes-Silva, Rejeena Shrestha, Xingliang Guo, Kiran Kundu, Alexander Biederstädt, Luis Muniz-Feliciano, Gary M Deyter, Mecit Kaplan, Xin Ru Jiang, Enli Liu, Antrix Jain, Jason Roszik, Natalie Wall Fowlkes, Luisa Maren Solis Soto, Maria Gabriela Raso, Joseph D Khoury, Pei Lin, Francisco Vega, Navin Varadarajan, Ken Chen, David Marin, Elizabeth J Shpall, Katayoun Rezvani
CD28 costimulation augments CAR signaling in NK cells via the LCK/CD3Z/ZAP70 signaling axis. Cancer discovery (2024)
Muhammad Aminu, Lingzhi Hong, Natalie I Vokes, Stephanie Tzouanas Schmidt, Maliazurina Saad, Bo Zhu, Xiuning Li, Cascone Tina, Ajay Sheshadri, Bo Wang, David Jaffray, P Andrew Futreal, Jiun-Kae Jack Lee, Lauren Averett Byers, Don L Gibbons, John Victor Heymach, Ken Chen, Chao Cheng, Jianjun Zhang, Jia Wu
Joint multi-omics discriminant analysis with consistent representation learning using PANDA. Research square (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Qingnan Liang, Luisa Solis Soto, Cara Haymaker, Ken Chen
Interpretable Spatial Gradient Analysis for Spatial Transcriptomics Data. bioRxiv : the preprint server for biology (2024)
Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J McGrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng
Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection. Nature communications 15 (1) (2024)
Ken Chen, Shaoheng Liang, Jinzhuang Dou, Ramiz Iqbal
Batch-Corrected Distance Mitigates Temporal and Spatial Variability for Clustering and Visualization of Single-Cell Gene Expression Data. Research square (2023)
Sunita Keshari, Alexander S Shavkunov, Qi Miao, Akata Saha, Charmelle D Williams, Anna M Highsmith, Josué E Pineda, Elise Alspach, Kenneth H Hu, Kristen E Pauken, Ken Chen, Matthew M Gubin
Overlapping and Distinct Mechanisms of Effective Neoantigen Cancer Vaccines and Immune Checkpoint Therapy. bioRxiv : the preprint server for biology (2023)
Sunita Keshari, Alexander S Shavkunov, Qi Miao, Akata Saha, Charmelle D Williams, Anna M Highsmith, Josué E Pineda, Elise Alspach, Kenneth H Hu, Kristen E Pauken, Ken Chen, Matthew M Gubin
Overlapping and Distinct Mechanisms of Effective Neoantigen Cancer Vaccines and Immune Checkpoint Therapy. bioRxiv : the preprint server for biology (2023)
Qingnan Liang, Yuefan Huang, Shan He, Ken Chen
Pathway centric analysis for single-cell RNA-seq and spatial transcriptomics data with GSDensity. Nature communications 14 (1) (2023)
Qingnan Liang, Yuefan Huang, Shan He, Ken Chen
Pathway centric analysis for single-cell RNA-seq and spatial transcriptomics data with GSDensity. Nature communications 14 (1) (2023)
Huihui Fan, Feng Wang, Andy Zeng, Alex Murison, Katarzyna Tomczak, Dapeng Hao, Fatima Zahra Jelloul, Bofei Wang, Praveen Barrodia, Shaoheng Liang, Ken Chen, Linghua Wang, Zhong-Ming Zhao, Kunal Rai, Abhinav K Jain, John Dick, Naval Daver, P Andrew Futreal, Hussein A Abbas
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance. Communications biology 6 (1) (2023)
Tapsi Kumar, Kevin Nee, Runmin Wei, Siyuan He, Quy H Nguyen, Shanshan Bai, Kerrigan Blake, Maren Pein, Yanwen Gong, Emi Sei, Min Hu, Anna K Casasent, Aatish Thennavan, Jianzhuo Li, Tuan Tran, Ken Chen, Benedikt Nilges, Nachiket Kashikar, Oliver Braubach, Bassem Ben Cheikh, Nadya Nikulina, Hui Chen, Mediget Teshome, Brian A Menegaz, Huma Javaid, Chandandeep Nagi, Jessica Montalvan, Tatyana Lev, Sharmila Mallya, Delia F Tifrea, Robert Edwards, Erin Lin, Ritesh Parajuli, Summer E Hanson, Sebastian Winocour, Alastair Thompson, Bora Lim, Devon A Lawson, Kai Kessenbrock, Nicholas E Navin
A spatially resolved single-cell genomic atlas of the adult human breast. Nature (2023)
Qingnan Liang, Yuefan Huang, Shan He, Ken Chen
Pathway centric analysis for single-cell RNA-seq and spatial transcriptomics data with GSDensity. Nature communications 14 (1) (2023)
Yuefan Huang, Vakul Mohanty, Merve Dede, Kyle Tsai, May Daher, Li Li, Katayoun Rezvani, Ken Chen
Characterizing cancer metabolism from bulk and single-cell RNA-seq data using METAFlux. Nature communications 14 (1) (2023)
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