Guillermina Lozano

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 43

Top Venues

Cancer research communications

Science advances

Proceedings of the National Academy of Sciences of the United States of America

Cancer research

The University of Texas MD Anderson Cancer Center

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Texas MD Anderson Cancer Center Sep 01 1987

United States

Professor and Chair :: Genetics

Publications

Denada Dibra, Shunbin Xiong, Sydney M Moyer, Adel K El-Naggar, Yuan Qi, Xiaoping Su, Elisabeth K Kong, Anil Korkut, Guillermina Lozano
Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo. Science advances 10 (7) (2024)
Phaedra C Ghazi, Kayla T O'Toole, Sanjana Srinivas Boggaram, Michael T Scherzer, Mark R Silvis, Yun Zhang, Madhumita Bogdan, Bryan D Smith, Guillermina Lozano, Daniel L Flynn, Eric L Snyder, Conan G Kinsey, Martin McMahon
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer. eLife 13 (2024)
Joy M McDaniel, Rhiannon L Morrissey, Denada Dibra, Lalit R Patel, Shunbin Xiong, Yun Zhang, Gilda P Chau, Xiaoping Su, Yuan Qi, Adel K El-Naggar, Guillermina Lozano
p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator. Cancer research communications (2024)
Susana Castro-Pando, Rian M Howell, Le Li, Marilina Mascaro, Erika Y Faraoni, Olivereen Le Roux, David Romanin, Virginia Tahan, Erick Riquelme, Yu Zhang, Jay K Kolls, James P Allison, Guillermina Lozano, Seyed Javad Moghaddam, Florencia McAllister
Pancreatic Epithelial IL17/IL17RA Signaling Drives B7-H4 Expression to Promote Tumorigenesis. Cancer immunology research 12 (9) (2024)
Joy M McDaniel, Rhiannon L Morrissey, Denada Dibra, Lalit R Patel, Shunbin Xiong, Yun Zhang, Gilda P Chau, Xiaoping Su, Yuan Qi, Adel K El-Naggar, Guillermina Lozano
p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator. Cancer research communications 4 (8) (2024)
Joy M McDaniel, Rhiannon L Morrissey, Denada Dibra, Lalit R Patel, Shunbin Xiong, Yun Zhang, Gilda P Chau, Xiaoping Su, Yuan Qi, Adel K El-Naggar, Guillermina Lozano
p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator. Cancer research communications 4 (8) (2024)
Denada Dibra, Shunbin Xiong, Sydney M Moyer, Adel K El-Naggar, Yuan Qi, Xiaoping Su, Elisabeth K Kong, Anil Korkut, Guillermina Lozano
Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo. Science advances 10 (7) (2024)
Phaedra C Ghazi, Kayla T O'Toole, Sanjana Srinivas Boggaram, Michael T Scherzer, Mark R Silvis, Yun Zhang, Madhumita Bogdan, Bryan D Smith, Guillermina Lozano, Daniel L Flynn, Eric L Snyder, Conan G Kinsey, Martin McMahon
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer. eLife 13 (2024)
Susana Castro-Pando, Rian M Howell, Le Li, Marilina Mascaro, Erika Y Faraoni, Olivereen Le Roux, David Romanin, Virginia Tahan, Erick Riquelme, Yu Zhang, Jay K Kolls, James P Allison, Guillermina Lozano, Seyed Javad Moghaddam, Florencia McAllister
Pancreatic epithelial IL-17/IL-17RA signaling drives B7-H4 expression to promote tumorigenesis. Cancer immunology research (2024)
Joy M McDaniel, Rhiannon L Morrissey, Denada Dibra, Lalit R Patel, Shunbin Xiong, Yun Zhang, Gilda P Chau, Xiaoping Su, Yuan Qi, Adel K El-Naggar, Guillermina Lozano
p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator. Cancer research communications 4 (8) (2024)
Phaedra C Ghazi, Kayla T O'Toole, Sanjana Srinivas Boggaram, Michael T Scherzer, Mark R Silvis, Yun Zhang, Madhumita Bogdan, Bryan D Smith, Guillermina Lozano, Daniel L Flynn, Eric L Snyder, Conan G Kinsey, Martin McMahon
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer. bioRxiv : the preprint server for biology (2024)
Joy M McDaniel, Rhiannon L Morrissey, Denada Dibra, Lalit R Patel, Shunbin Xiong, Yun Zhang, Gilda P Chau, Xiaoping Su, Yuan Qi, Adel K El-Naggar, Guillermina Lozano
p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator. Cancer research communications 4 (8) (2024)
Denada Dibra, Shunbin Xiong, Sydney M Moyer, Adel K El-Naggar, Yuan Qi, Xiaoping Su, Elisabeth K Kong, Anil Korkut, Guillermina Lozano
Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo. Science advances 10 (7) (2024)
Phaedra C Ghazi, Kayla T O'Toole, Sanjana Srinivas Boggaram, Michael T Scherzer, Mark R Silvis, Yun Zhang, Madhumita Bogdan, Bryan D Smith, Guillermina Lozano, Daniel L Flynn, Eric L Snyder, Conan G Kinsey, Martin McMahon
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer. bioRxiv : the preprint server for biology (2024)
Phaedra C Ghazi, Kayla T O'Toole, Sanjana Srinivas Boggaram, Michael T Scherzer, Mark R Silvis, Yun Zhang, Madhumita Bogdan, Bryan D Smith, Guillermina Lozano, Daniel L Flynn, Eric L Snyder, Conan G Kinsey, Martin McMahon
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer. bioRxiv : the preprint server for biology (2024)
Denada Dibra, Shunbin Xiong, Sydney M Moyer, Adel K El-Naggar, Yuan Qi, Xiaoping Su, Elisabeth K Kong, Anil Korkut, Guillermina Lozano
Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo. Science advances 10 (7) (2024)
Denada Dibra, Mihai Gagea, Yuan Qi, Gilda P Chau, Xiaoping Su, Guillermina Lozano
p53R245W mutation fuels cancer initiation and metastases in NASH-driven liver tumorigenesis. Cancer research communications (2023)
Dhruv Chachad, Lalit R Patel, Carlos Vera Recio, Rasoul Pourebrahim, Elizabeth M Whitley, Wenyi Wang, Xiaoping Su, An Xu, Dung-Fang Lee, Guillermina Lozano
Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants. Cancer research (2023)
Chang Sun, Yuan Qi, Natalie Fowlkes, Nina Lazic, Xiaoping Su, Guillermina Lozano, Amanda R Wasylishen
The histone chaperone function of Daxx is dispensable for embryonic development. Cell death & disease 14 (8) (2023)
Vinod Pant, Chang Sun, Guillermina Lozano
Tissue specificity and spatio-temporal dynamics of the p53 transcriptional program. Cell death and differentiation (2023)
Vinod Pant, Chang Sun, Guillermina Lozano
Tissue specificity and spatio-temporal dynamics of the p53 transcriptional program. Cell death and differentiation (2023)
Jovanka Gencel-Augusto, Xiaoping Su, Yuan Qi, Elizabeth M Whitley, Vinod Pant, Shunbin Xiong, Vrutant V Shah, Jerome Lin, Encarnacion Perez, Marta L Fiorotto, Iqbal Mahmud, Abhinav K Jain, Philip L Lorenzi, Nicholas E Navin, Ellen R Richie, Guillermina Lozano
Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer discovery (2023)
Denada Dibra, Sydney M Moyer, Adel K El-Naggar, Yuan Qi, Xiaoping Su, Guillermina Lozano
Triple-negative breast tumors are dependent on mutant p53 for growth and survival. Proceedings of the National Academy of Sciences of the United States of America 120 (34) (2023)
Xiaojie Yu, Yun Zhang, Shunbin Xiong, Joy M McDaniel, Chang Sun, Gilda P Chau, Jovanka Gencel-Augusto, Dhruv Chachad, Rhiannon L Morrissey, Xiayu Rao, Jing Wang, Guillermina Lozano
Omics analyses of a somatic <i>Trp53<sup>R245W/+</sup></i> breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling. Proceedings of the National Academy of Sciences of the United States of America 119 (45) (2022)
Michelle Craig Barton, Guillermina Lozano
p53 Activation Paradoxically Causes Liver Cancer. Cancer research 82 (16) (2022)
Rhiannon L Morrissey, Alastair M Thompson, Guillermina Lozano
Is loss of p53 a driver of ductal carcinoma in situ progression? British journal of cancer 127 (10) (2022)
Shunbin Xiong, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun, Gilda P Chau, Yuan Qi, Xiaoping Su, Elizabeth M Whitley, Adel K El-Naggar, Guillermina Lozano
Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo. Cancer research 82 (10) (2022)
Vinod Pant, Neeraj K Aryal, Shunbin Xiong, Gilda P Chau, Natalie Wall Fowlkes, Guillermina Lozano
Alterations of the Mdm2 C-Terminus Differentially Impact Its Function In Vivo. Cancer research 82 (7) (2022)
Chang Sun, Jeannelyn S Estrella, Elizabeth M Whitley, Gilda P Chau, Guillermina Lozano, Amanda R Wasylishen
Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas. Disease models & mechanisms 15 (8) (2022)
Javier Octavio Mejía-Hernández, Simon Paul Keam, Reem Saleh, Fenella Muntz, Stephen B Fox, David Byrne, Arielle Kogan, Lokman Pang, Jennifer Huynh, Cassandra Litchfield, Franco Caramia, Guillermina Lozano, Hua He, James M You, Shahneen Sandhu, Scott G Williams, Ygal Haupt, Sue Haupt
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss. Cell death & disease 13 (9) (2022)
John R Jeffers, Emilia Modolo Pinto, Jerold E Rehg, Michael R Clay, Jinling Wang, Geoffrey A Neale, Richard J Heath, Guillermina Lozano, Enzo Lalli, Bonald Cavalcante de Figueiredo, Alberto S Pappo, Carlos Rodriguez-Galindo, Wenan Chen, Stanley Pounds, Raul C Ribeiro, Gerard P Zambetti
The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model. Cancer research 81 (9) (2021)
Michael P Kim, Xinqun Li, Jenying Deng, Yun Zhang, Bingbing Dai, Kendra L Allton, Tara G Hughes, Christian Siangco, Jithesh J Augustine, Ya'an Kang, Joy M McDaniel, Shunbin Xiong, Eugene Jon Koay, Florencia McAllister, Christopher A Bristow, Timothy P Heffernan, Anirban Maitra, Bin Liu, Michelle Craig Barton, Amanda R Wasylishen, Jason B Fleming, Guillermina Lozano
Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis. Cancer discovery 11 (8) (2021)
Xin Zhou, Allyson Beilter, Zhaohui Xu, Ruli Gao, Shunbin Xiong, Adriana Paulucci-Holthauzen, Guillermina Lozano, Benoit de Crombrugghe, Richard G Gorlick
Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells. Cell death & disease 12 (6) (2021)
Edith A Perez, Elizabeth D Thompson, John Whyte, Cheryl A Boyce, John D Carpten, Guillermina Lozano, Raymond M Williams, Karen M Winkfield, David Bernstein, Sung Poblete
Analysis of Population Differences in Digital Conversations About Cancer Clinical Trials: Advanced Data Mining and Extraction Study. JMIR cancer 7 (3) (2021)
Vrutant V Shah, Aundrietta D Duncan, Shiming Jiang, Sabrina A Stratton, Kendra L Allton, Clinton Yam, Abhinav Jain, Patrick M Krause, Yue Lu, Shirong Cai, Yizheng Tu, Xinhui Zhou, Xiaomei Zhang, Yan Jiang, Christopher L Carroll, Zhijun Kang, Bin Liu, Jianjun Shen, Mihai Gagea, Sebastian M Manu, Lei Huo, Michael Gilcrease, Reid T Powell, Lei Guo, Clifford Stephan, Peter J Davies, Jan Parker-Thornburg, Guillermina Lozano, Richard R Behringer, Helen Piwnica-Worms, Jeffrey T Chang, Stacy L Moulder, Michelle Craig Barton
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. Nature communications 12 (1) (2021)
Jovanka Gencel-Augusto, Guillermina Lozano
p53 tetramerization: at the center of the dominant-negative effect of mutant p53. Genes & development 34 (17-18) (2021)
Amanda R Wasylishen, Chang Sun, Sydney M Moyer, Yuan Qi, Gilda P Chau, Neeraj K Aryal, Florencia McAllister, Michael P Kim, Michelle Craig Barton, Jeannelyn S Estrella, Xiaoping Su, Guillermina Lozano
Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo. Science advances 6 (32) (2020)
Amanda R Wasylishen, Chang Sun, Gilda P Chau, Yuan Qi, Xiaoping Su, Michael P Kim, Jeannelyn S Estrella, Guillermina Lozano
Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress. Proceedings of the National Academy of Sciences of the United States of America 117 (12) (2020)
Sydney M Moyer, Amanda R Wasylishen, Yuan Qi, Natalie Fowlkes, Xiaoping Su, Guillermina Lozano
p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo. Proceedings of the National Academy of Sciences of the United States of America 117 (38) (2020)
Vinod Pant, Shunbin Xiong, Amanda R Wasylishen, Connie A Larsson, Neeraj K Aryal, Gilda Chau, Ramesh C Tailor, Guillermina Lozano
Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity. Proceedings of the National Academy of Sciences of the United States of America 116 (35) (2019)
Sue Haupt, Franco Caramia, Alan Herschtal, Thierry Soussi, Guillermina Lozano, Hu Chen, Han Liang, Terence P Speed, Ygal Haupt
Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network. Nature communications 10 (1) (2019)
Yun Zhang, Shunbin Xiong, Bin Liu, Vinod Pant, Francis Celii, Gilda Chau, Ana C Elizondo-Fraire, Peirong Yang, Mingjian James You, Adel K El-Naggar, Nicholas E Navin, Guillermina Lozano
Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases. Nature communications 9 (1) (2018)
Neeraj K Aryal, Amanda R Wasylishen, Guillermina Lozano
CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo. Cell death & disease 9 (11) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Guillermina Lozano