Helen Piwnica-Worms

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 21

Top Topics

Top Venues

NPJ breast cancer

Cancer discovery

Nature communications

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Reid T Powell, Amanda L Rinkenbaugh, Lei Guo, Shirong Cai, Jiansu Shao, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Chunxiao Fu, Yuan Qi, Faiza Baameur Hancock, Jason B White, Clifford Stephen, Peter J A Davies, Stacy Moulder, William Fraser Symmans, Jeffrey T Chang, Helen Piwnica-Worms
Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer. NPJ breast cancer 10 (1) (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer discovery 14 (8) (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer discovery 14 (8) (2024)
Reid T Powell, Amanda L Rinkenbaugh, Lei Guo, Shirong Cai, Jiansu Shao, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Chunxiao Fu, Yuan Qi, Faiza Baameur Hancock, Jason B White, Clifford Stephen, Peter J A Davies, Stacy Moulder, William Fraser Symmans, Jeffrey T Chang, Helen Piwnica-Worms
Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer. NPJ breast cancer 10 (1) (2024)
Reid T Powell, Amanda L Rinkenbaugh, Lei Guo, Shirong Cai, Jiansu Shao, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Chunxiao Fu, Yuan Qi, Faiza Baameur Hancock, Jason B White, Clifford Stephen, Peter J A Davies, Stacy Moulder, William Fraser Symmans, Jeffrey T Chang, Helen Piwnica-Worms
Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer. NPJ breast cancer 10 (1) (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers. Cancer discovery (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers. Cancer discovery (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer discovery 14 (8) (2024)
Gloria V Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B Redwood, Yan Jiang, Aaron McCoy, Amanda L Rinkenbaugh, Rosanna Lau, Alexander J Trevarton, Chunxiao Fu, Rebekah Gould, Elizabeth E Ravenberg, Lei Huo, Rosalind Candelaria, Lumarie Santiago, Beatriz E Adrada, Deanna L Lane, Gaiane M Rauch, Wei T Yang, Jason B White, Jeffrey T Chang, Stacy L Moulder, William Fraser Symmans, Susan G Hilsenbeck, Helen Piwnica-Worms
Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer. NPJ breast cancer 9 (1) (2023)
Gloria V Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B Redwood, Yan Jiang, Aaron McCoy, Amanda L Rinkenbaugh, Rosanna Lau, Alexander J Trevarton, Chunxiao Fu, Rebekah Gould, Elizabeth E Ravenberg, Lei Huo, Rosalind Candelaria, Lumarie Santiago, Beatriz E Adrada, Deanna L Lane, Gaiane M Rauch, Wei T Yang, Jason B White, Jeffrey T Chang, Stacy L Moulder, William Fraser Symmans, Susan G Hilsenbeck, Helen Piwnica-Worms
Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer. NPJ breast cancer 9 (1) (2023)
Gloria V Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B Redwood, Yan Jiang, Aaron McCoy, Amanda L Rinkenbaugh, Rosanna Lau, Alexander J Trevarton, Chunxiao Fu, Rebekah Gould, Elizabeth E Ravenberg, Lei Huo, Rosalind Candelaria, Lumarie Santiago, Beatriz E Adrada, Deanna L Lane, Gaiane M Rauch, Wei T Yang, Jason B White, Jeffrey T Chang, Stacy L Moulder, William Fraser Symmans, Susan G Hilsenbeck, Helen Piwnica-Worms
Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer. NPJ breast cancer 9 (1) (2023)
Xuan Liu, Zhongqi Ge, Fei Yang, Alejandro Contreras, Sanghoon Lee, Jason B White, Yiling Lu, Marilyne Labrie, Banu K Arun, Stacy L Moulder, Gordon B Mills, Helen Piwnica-Worms, Jennifer K Litton, Jeffrey T Chang
Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers. NPJ breast cancer 8 (1) (2022)
Abena B Redwood, Xiaomei Zhang, Sahil B Seth, Zhongqi Ge, Wendy E Bindeman, Xinhui Zhou, Vidya C Sinha, Timothy P Heffernan, Helen Piwnica-Worms
The cytosolic iron-sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors. NPJ breast cancer 7 (1) (2021)
Appalaraju Jaggupilli, Stanley Ly, Khoa Nguyen, Vivek Anand, Bin Yuan, Fouad El-Dana, Yuanqing Yan, Zoe Arvanitis, Danthasinghe Waduge Badrajee Piyarathna, Nagireddy Putluri, Helen Piwnica-Worms, Henry Charles Manning, Michael Andreeff, Venkata Lokesh Battula
Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer. British journal of cancer (2021)
Vrutant V Shah, Aundrietta D Duncan, Shiming Jiang, Sabrina A Stratton, Kendra L Allton, Clinton Yam, Abhinav Jain, Patrick M Krause, Yue Lu, Shirong Cai, Yizheng Tu, Xinhui Zhou, Xiaomei Zhang, Yan Jiang, Christopher L Carroll, Zhijun Kang, Bin Liu, Jianjun Shen, Mihai Gagea, Sebastian M Manu, Lei Huo, Michael Gilcrease, Reid T Powell, Lei Guo, Clifford Stephan, Peter J Davies, Jan Parker-Thornburg, Guillermina Lozano, Richard R Behringer, Helen Piwnica-Worms, Jeffrey T Chang, Stacy L Moulder, Michelle Craig Barton
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. Nature communications 12 (1) (2021)
Vidya C Sinha, Amanda L Rinkenbaugh, Mingchu Xu, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Jiansu Shao, Yuan Qi, John A Zebala, Dean Y Maeda, Florencia McAllister, Helen Piwnica-Worms
Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast. Nature communications 12 (1) (2021)
Gloria V Echeverria, Zhongqi Ge, Sahil B Seth, Xiaomei Zhang, Sabrina Jeter-Jones, Xinhui Zhou, Shirong Cai, Yizheng Tu, Aaron McCoy, Michael D Peoples, Yuting Sun, Huan Qiu, Qing Chang, Christopher Bristow, Alessandro Carugo, Jiansu Shao, Xiaoyan Ma, Angela L Harris, Prabhjot Mundi, Rosanna Lau, Vandhana Ramamoorthy, Yun Wu, Mariano J Alvarez, Andrea Califano, Stacy L Moulder, William Fraser Symmans, Joseph R Marszalek, Timothy P Heffernan, Jeffrey T Chang, Helen Piwnica-Worms
Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state. Science translational medicine 11 (488) (2020)
Xiaohui Hu, Samuel E Harvey, Rong Zheng, Jingyi Lyu, Caitlin L Grzeskowiak, Emily Powell, Helen Piwnica-Worms, Kenneth L Scott, Chonghui Cheng
The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing. Nature communications 11 (1) (2020)
Tara N Fujimoto, Lauren E Colbert, Yanqing Huang, Jessica M Molkentine, Amit Deorukhkar, Laura Baseler, Marimar de la Cruz Bonilla, Meifang Yu, Daniel Lin, Sonal Gupta, Peter K Cabeceiras, Charles V Kingsley, Ramesh C Tailor, Gabriel O Sawakuchi, Eugene Jon Koay, Helen Piwnica-Worms, Anirban Maitra, Cullen M Taniguchi
Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer research 79 (9) (2020)
Sunil Acharya, Jun Yao, Ping Li, Chenyu Zhang, Frank J Lowery, Qingling Zhang, Hua Guo, Jingkun Qu, Fei Yang, Ignacio I Wistuba, Helen Piwnica-Worms, Aysegul A Sahin, Dihua Yu
Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer. Cancer research 79 (16) (2019)
Vidya C Sinha, Helen Piwnica-Worms
Intratumoral Heterogeneity in Ductal Carcinoma In Situ: Chaos and Consequence. Journal of mammary gland biology and neoplasia 23 (4) (2018)