Han Liang (H Liang)

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 60

Top Topics

Prostate Cancer

Top Venues

Nature communications

Cancer discovery

Science advances

Nature genetics

This page only lists publications with an associated author ORCID identifier.

Publications

Chiho Kim, Xu-Dong Wang, Zhengshuai Liu, Jianwei Hao, Shuai Wang, Peng Li, Zhenzhen Zi, Qing Ding, Seoyeon Jang, Jiwoong Kim, Yikai Luo, Kenneth E Huffman, Shreoshi Pal Choudhuri, Sofia Del Rio, Ling Cai, Han Liang, Benjamin J Drapkin, John D Minna, Yonghao Yu
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science advances 10 (3) (2024)
Chiho Kim, Xu-Dong Wang, Zhengshuai Liu, Jianwei Hao, Shuai Wang, Peng Li, Zhenzhen Zi, Qing Ding, Seoyeon Jang, Jiwoong Kim, Yikai Luo, Kenneth E Huffman, Shreoshi Pal Choudhuri, Sofia Del Rio, Ling Cai, Han Liang, Benjamin J Drapkin, John D Minna, Yonghao Yu
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science advances 10 (3) (2024)
Sara Corvigno, Yuan Liu, Emine Bayraktar, Elaine Stur, Nazende Nur Bayram, Adrian Lankenau Ahumada, Supriya Nagaraju, Cristian Rodríguez-Aguayo, Hu Chen, Thanh Chung Vu, Yunfei Wen, Han Liang, Li Zhao, Sanghoon Lee, Gabriel Lopez-Berestein, Anil K Sood
Enhanced plant-derived vesicles for nucleotide delivery for cancer therapy. NPJ precision oncology 8 (1) (2024)
Chiho Kim, Xu-Dong Wang, Zhengshuai Liu, Jianwei Hao, Shuai Wang, Peng Li, Zhenzhen Zi, Qing Ding, Seoyeon Jang, Jiwoong Kim, Yikai Luo, Kenneth E Huffman, Shreoshi Pal Choudhuri, Sofia Del Rio, Ling Cai, Han Liang, Benjamin J Drapkin, John D Minna, Yonghao Yu
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science advances 10 (3) (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery (2024)
Chiho Kim, Xu-Dong Wang, Zhengshuai Liu, Jianwei Hao, Shuai Wang, Peng Li, Zhenzhen Zi, Qing Ding, Seoyeon Jang, Jiwoong Kim, Yikai Luo, Kenneth E Huffman, Shreoshi Pal Choudhuri, Sofia Del Rio, Ling Cai, Han Liang, Benjamin J Drapkin, John D Minna, Yonghao Yu
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science advances 10 (3) (2024)
Sara Corvigno, Yuan Liu, Emine Bayraktar, Elaine Stur, Nazende Nur Bayram, Adrian Lankenau Ahumada, Supriya Nagaraju, Cristian Rodríguez-Aguayo, Hu Chen, Thanh Chung Vu, Yunfei Wen, Han Liang, Li Zhao, Sanghoon Lee, Gabriel Lopez-Berestein, Anil K Sood
Enhanced plant-derived vesicles for nucleotide delivery for cancer therapy. NPJ precision oncology 8 (1) (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery 14 (8) (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery 14 (8) (2024)
Chiho Kim, Xu-Dong Wang, Zhengshuai Liu, Jianwei Hao, Shuai Wang, Peng Li, Zhenzhen Zi, Qing Ding, Seoyeon Jang, Jiwoong Kim, Yikai Luo, Kenneth E Huffman, Shreoshi Pal Choudhuri, Sofia Del Rio, Ling Cai, Han Liang, Benjamin J Drapkin, John D Minna, Yonghao Yu
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors. Science advances 10 (3) (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery 14 (8) (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery (2024)
Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjostrom, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla Rodriguez Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Juliet Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng Hansen He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer. Cancer discovery (2024)
Jun Li, Wei Liu, Kamalika Mojumdar, Hong Kim, Zhicheng Zhou, Zhenlin Ju, Shwetha V Kumar, Patrick Kwok-Shing Ng, Han Chen, Michael A Davies, Yiling Lu, Rehan Akbani, Gordon B Mills, Han Liang
A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies. Nature cancer (2024)
Sara Corvigno, Yuan Liu, Emine Bayraktar, Elaine Stur, Nazende Nur Bayram, Adrian Lankenau Ahumada, Supriya Nagaraju, Cristian Rodríguez-Aguayo, Hu Chen, Thanh Chung Vu, Yunfei Wen, Han Liang, Li Zhao, Sanghoon Lee, Gabriel Lopez-Berestein, Anil K Sood
Enhanced plant-derived vesicles for nucleotide delivery for cancer therapy. NPJ precision oncology 8 (1) (2024)
Weiwei Lin, Yikai Luo, Jie Wu, Haowan Zhang, Ge Jin, Chahua Guo, Hang Zhou, Han Liang, Xiaoyan Xu
Loss of ADAR1 in macrophages in combination with interferon gamma suppresses tumor growth by remodeling the tumor microenvironment. Journal for immunotherapy of cancer 11 (11) (2023)
Chunjing Bao, Ou-Yang Chen, Huaxin Sheng, Jeffrey Zhang, Yikai Luo, Byron W Hayes, Han Liang, Wolfgang B Liedtke, Ru-Rong Ji, Soman N Abraham
A mast cell-thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis. Science immunology 8 (81) (2023)
Chunjing Bao, Ou-Yang Chen, Huaxin Sheng, Jeffrey Zhang, Yikai Luo, Byron W Hayes, Han Liang, Wolfgang B Liedtke, Ru-Rong Ji, Soman N Abraham
A mast cell-thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis. Science immunology 8 (81) (2023)
Chunjing Bao, Ou-Yang Chen, Huaxin Sheng, Jeffrey Zhang, Yikai Luo, Byron W Hayes, Han Liang, Wolfgang B Liedtke, Ru-Rong Ji, Soman N Abraham
A mast cell-thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis. Science immunology 8 (81) (2023)
Xin Shen, Xianzhi Gao, Yikai Luo, Qianying Xu, Ying Fan, Shenghui Hong, Zhengwei Huang, Xiaoqian Liu, Qianqian Wang, Zuojia Chen, Di Wang, Linrong Lu, Chuan Wu, Han Liang, Lie Wang
Cxxc finger protein 1 maintains homeostasis and function of intestinal group 3 innate lymphoid cells with aging. Nature aging (2023)
Yikai Luo, Han Liang
Cancer Cells Employ the Most Prolific RNA Editors: A Closer Look at the Single-Cell Level. Cancer research 83 (3) (2023)
Yikai Luo, Han Liang
Cancer Cells Employ the Most Prolific RNA Editors: A Closer Look at the Single-Cell Level. Cancer research 83 (3) (2023)
Chunjing Bao, Ou-Yang Chen, Huaxin Sheng, Jeffrey Zhang, Yikai Luo, Byron W Hayes, Han Liang, Wolfgang B Liedtke, Ru-Rong Ji, Soman N Abraham
A mast cell-thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis. Science immunology 8 (81) (2023)
Lei Li, Yu Gu, Mengpei Zhang, Xiaohua Shi, Zhe Li, Xinyun Xu, Tianqi Sun, Yu Dong, Chao Xue, Xiaoru Zhu, Ran Lv, Kai Jiao, Xuwo Ji, Li-Juan Wang, Yang Zhang, Zhiyong Liang, Ying Jin, Rutie Yin, Ming Wu, Han Liang
HRD effects on first-line adjuvant chemotherapy and PARPi maintenance therapy in Chinese ovarian cancer patients. NPJ precision oncology 7 (1) (2023)
Yikai Luo, Han Liang
Cancer Cells Employ the Most Prolific RNA Editors: A Closer Look at the Single-Cell Level. Cancer research 83 (3) (2023)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2023)
Yikai Luo, Han Liang
Cancer Cells Employ the Most Prolific RNA Editors: A Closer Look at the Single-Cell Level. Cancer research 83 (3) (2023)
Jun Li, Hengyu Lu, Patrick Kwok-Shing Ng, Angeliki Pantazi, Carman Ka Man Ip, Kang Jin Jeong, Bianca Amador, Richard Tran, Yiu Huen Tsang, Lixing Yang, Xingzhi Song, Turgut Dogruluk, Xiaojia Ren, Angela Hadjipanayis, Christopher A Bristow, Semin Lee, Melanie Kucherlapati, Michael Parfenov, Jiabin Tang, Sahil B Seth, Harshad S Mahadeshwar, Kamalika Mojumdar, Dong Zeng, Jianhua Zhang, Alexei Protopopov, Jonathan G Seidman, Chad J Creighton, Yiling Lu, Nidhi Sahni, Kenna R Shaw, Funda Meric-Bernstam, P Andrew Futreal, Lynda Chin, Kenneth L Scott, Raju Kucherlapati, Gordon B Mills, Han Liang
A functional genomic approach to actionable gene fusions for precision oncology. Science advances 8 (6) (2022)
Andrew W Hahn, Ashley V Menk, Dayana B Rivadeneira, Ryan C Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K Mishra, Tuba Nur Gide, Camelia Quek, Yan Zang, Christine N Spencer, Alexander M Menzies, Carrie R Daniel-MacDougall, Courtney W Hudgens, Theodore Scott Nowicki, Lauren E Haydu, Md Abdul Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M Burton, Jared C Malke, Julie M Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E Woodman, Vashisht Gopal Y N, Renato A Guerrieri, Grant M Fischer, Jian Wang, Khalida M Wani, John F Thompson, Jeffrey E Lee, Patrick Hwu, Nadim J Ajami, Jeffrey E Gershenwald, Georgina V Long, Richard A Scolyer, Michael T Tetzlaff, Alexander J F Lazar, Dirk Schadendorf, Jennifer A Wargo, Joanne M Jeter, Ralph J DeBerardinis, Han Liang, P Andrew Futreal, Jianhua Zhang, James S Wilmott, Weiyi Peng, Michael A Davies, Greg M Delgoffe, Yana G Najjar, Jennifer Leigh McQuade
Obesity is associated with altered tumor metabolism in metastatic melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Masashi Fujita, Mei-Ju May Chen, Doris Rieko Siwak, Shota Sasagawa, Ayako Oosawa-Tatsuguchi, Koji Arihiro, Atsushi Ono, Ryoichi Miura, Kazuhiro Maejima, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuaki Chayama, Ju-Seog Lee, Yiling Lu, Gordon B Mills, Han Liang, Satoshi S Nishizuka, Hidewaki Nakagawa
Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets. Nature communications 13 (1) (2022)
Han Liang
Finding cancer drivers in the UPS system. Nature cancer 1 (1) (2022)
Xinxin Peng, Yikai Luo, Hongyue Li, Xuejiao Guo, Hu Chen, Xuwo Ji, Han Liang
RNA editing increases the nucleotide diversity of SARS-CoV-2 in human host cells. PLoS genetics 18 (3) (2022)
Fan Yao, Yalan Deng, Yang Zhao, Ying Mei, Yilei Zhang, Xiaoguang Liu, Consuelo Martinez, Xiaohua Su, Roberto R Rosato, Hongqi Teng, Qinglei Hang, Shannon Yap, Dahu Chen, Yumeng Wang, Mei-Ju May Chen, Mutian Zhang, Han Liang, Dong Xie, Xin Chen, Hao Zhu, Jenny C Chang, M James You, Yutong Sun, Boyi Gan, Li Ma
A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nature communications 12 (1) (2021)
Xuan Zong, Ying Zhang, Xinxin Peng, Dongyan Cao, Mei Yu, Jinhui Wang, Hongyue Li, Xuejiao Guo, Han Liang, Jia-Xin Yang
Analysis of the genomic landscape of yolk sac tumors reveals mechanisms of evolution and chemoresistance. Nature communications 12 (1) (2021)
Jianzhen Lin, Xinxin Peng, Kun Dong, Junyu Long, Xuejiao Guo, Hongyue Li, Yi Bai, Xu Yang, Dongxu Wang, Xin Lu, Yilei Mao, Xinting Sang, Xuwo Ji, Haitao Zhao, Han Liang
Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer. Nature communications 12 (1) (2021)
Ying Mei, Mei-Ju May Chen, Han Liang, Li Ma
A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma. Communications biology 4 (1) (2021)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2020)
Zi-Yu Li, Xiang-Yu Gao, Xinxin Peng, Mei-Ju May Chen, Zhe Li, Bin Wei, Xianzi Wen, Baoye Wei, Yu Dong, Zhaode Bu, Aiwen Wu, Qi Wu, Lei Tang, Zhongwu Li, Yiqiang Liu, Li Zhang, Shuqin Jia, Lianhai Zhang, Fei Shan, Ji Zhang, Xiaojiang Wu, Xin Ji, Ke Ji, Xiao-Long Wu, Jinyao Shi, Xiaofang Xing, Jianmin Wu, Guoqing Lv, Lin Shen, Xuwo Ji, Han Liang, Jia Fu Ji
Multi-omics characterization of molecular features of gastric cancer correlated with response to neoadjuvant chemotherapy. Science advances 6 (9) (2020)
Hu Chen, Jun Li, Yumeng Wang, Patrick Kwok-Shing Ng, Yiu Huen Tsang, Kenna R Shaw, Gordon B Mills, Han Liang
Comprehensive assessment of computational algorithms in predicting cancer driver mutations. Genome biology 21 (1) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics 52 (3) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2020)
Sue Haupt, Franco Caramia, Alan Herschtal, Thierry Soussi, Guillermina Lozano, Hu Chen, Han Liang, Terence P Speed, Ygal Haupt
Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network. Nature communications 10 (1) (2019)
Youqiong Ye, Qingsong Hu, Hu Chen, Ke Liang, Yuan Yuan, Yu Xiang, Hang Ruan, Zhao Zhang, Anren Song, Huiwen Zhang, Lingxiang Liu, Lixia Diao, Yanyan Lou, Bingying Zhou, Li Wang, Shengtao Zhou, Jianjun Gao, Eric Jonasch, Steven H Lin, Yang Xia, Chunru Lin, Liuqing Yang, Gordon B Mills, Han Liang, Leng Han
Characterization of Hypoxia-associated Molecular Features to Aid Hypoxia-Targeted Therapy. Nature metabolism 1 (4) (2019)
Fan Yao, Zhicheng Zhou, Jongchan Kim, Qinglei Hang, Zhenna Xiao, Baochau N Ton, Liang Chang, Na Liu, Liyong Zeng, Wenqi Wang, Yumeng Wang, Peijing Zhang, Xiaoyu Hu, Xiaohua Su, Han Liang, Yutong Sun, Li Ma
SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nature communications 9 (1) (2018)
Wei-Chien Yuan, Brian Pepe-Mooney, Giorgio G Galli, Michael T Dill, Hai-Tsang Huang, Mingfeng Hao, Yumeng Wang, Han Liang, Raffaele A Calogero, Fernando D Camargo
NUAK2 is a critical YAP target in liver cancer. Nature communications 9 (1) (2018)
Jongchan Kim, Hai-Long Piao, Beom-Jun Kim, Fan Yao, Zhenbo Han, Yumeng Wang, Zhenna Xiao, Ashley N Siverly, Sarah E Lawhon, Baochau N Ton, Hyemin Lee, Zhicheng Zhou, Boyi Gan, Shinichi Nakagawa, Matthew J Ellis, Han Liang, Mien-Chie Hung, M James You, Yutong Sun, Li Ma
Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nature genetics 50 (12) (2018)
Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Zhongqi Ge, Zachary D Nagel, Jun Zou, Chen Wang, Prabodh Kapoor, Xiangyi Ma, Ding Ma, Jiyong Liang, Shumei Song, Jinsong Liu, Leona D Samson, Jaffer A Ajani, Guo-Min Li, Han Liang, Xuetong Shen, Gordon B Mills, Guang Peng
ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade. Nature medicine 24 (5) (2018)
Ivan Vannini, Petra M Wise, Kishore B Challagundla, Meropi Plousiou, Mirco Raffini, Erika Bandini, Francesca Fanini, Giorgia Paliaga, Melissa Crawford, Manuela Ferracin, Cristina Ivan, Linda Fabris, Ramana V Davuluri, Zhiyi Guo, Maria Angelica Cortez, Xinna Zhang, Lu Chen, Shuxing Zhang, Cecilia Fernandez-Cymering, Leng Han, Silvia Carloni, Samanta Salvi, Hui Ling, Mariam Murtadha, Paolo Neviani, Barbara J Gitlitz, Ite A Laird-Offringa, Patrick Nana-Sinkam, Massimo Negrini, Han Liang, Dino Amadori, Amelia Cimmino, George A Calin, Muller Fabbri
Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs. Nature communications 9 (1) (2018)
Hong Zhang, Yirong Wang, Jun Li, Han Chen, Xionglei He, Huiwen Zhang, Han Liang, Jian Lu
Biosynthetic energy cost for amino acids decreases in cancer evolution. Nature communications 9 (1) (2018)
Minying Zhang, Jens Fritsche, Jason Roszik, Leila J Williams, Xinxin Peng, Yulun Chiu, Chih-Chiang Tsou, Franziska Hoffgaard, Valentina Goldfinger, Oliver Schoor, Amjad Talukder, Marie A Forget, Cara Haymaker, Chantale Bernatchez, Leng Han, Yiu-Huen Tsang, Kathleen Kong, Xiaoyan Xu, Kenneth L Scott, Harpreet Singh-Jasuja, Greg Lizee, Han Liang, Toni Weinschenk, Gordon B Mills, Patrick Hwu
RNA editing derived epitopes function as cancer antigens to elicit immune responses. Nature communications 9 (1) (2018)
Min Jin Ha, Sayantan Banerjee, Rehan Akbani, Han Liang, Gordon B Mills, Kim-Anh Do, Veerabhadran Baladandayuthapani
Personalized Integrated Network Modeling of the Cancer Proteome Atlas. Scientific reports 8 (1) (2018)
Aifu Lin, Qingsong Hu, Chunlai Li, Zhen Xing, Guolin Ma, Cheng Wang, Jun Li, Yin Ye, Jun Yao, Ke Liang, Shouyu Wang, Peter K Park, Jeffrey R Marks, Yan Zhou, Jianwei Zhou, Mien-Chie Hung, Han Liang, Zhibin Hu, Hongbing Shen, David H Hawke, Leng Han, Yubin Zhou, Chunru Lin, Liuqing Yang
The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors. Nature cell biology 19 (3) (2017)
Chunlai Li, Shouyu Wang, Zhen Xing, Aifu Lin, Ke Liang, Jian Song, Qingsong Hu, Jun Yao, Zhongyuan Chen, Peter K Park, David H Hawke, Jianwei Zhou, Yan Zhou, Shuxing Zhang, Han Liang, Mien-Chie Hung, Gary E Gallick, Leng Han, Chunru Lin, Liuqing Yang
A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis. Nature cell biology 19 (2) (2017)
Zhen-Dong Xiao, Leng Han, Hyemin Lee, Li Zhuang, Yilei Zhang, Joelle Baddour, Deepak Nagrath, Christopher G Wood, Jian Gu, Xifeng Wu, Han Liang, Boyi Gan
Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development. Nature communications 8 (1) (2017)
Yang Li, Ping Xie, Liang Lu, Jian Wang, Lihong Diao, Zhongyang Liu, Feifei Guo, Yangzhige He, Yuan Liu, Qin Huang, Han Liang, Dong Li, Fuchu He
An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network. Nature communications 8 (1) (2017)
Ivan Vannini, Petra M Wise, Kishore B Challagundla, Meropi Plousiou, Mirco Raffini, Erika Bandini, Francesca Fanini, Giorgia Paliaga, Melissa Crawford, Manuela Ferracin, Cristina Ivan, Linda Fabris, Ramana V Davuluri, Zhiyi Guo, Maria Angelica Cortez, Xinna Zhang, Lu Chen, Shuxing Zhang, Cecilia Fernandez-Cymering, Leng Han, Silvia Carloni, Samanta Salvi, Hui Ling, Mariam Murtadha, Paolo Neviani, Barbara J Gitlitz, Ite A Laird-Offringa, Patrick Nana-Sinkam, Massimo Negrini, Han Liang, Dino Amadori, Amelia Cimmino, George A Calin, Muller Fabbri
Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs. Nature communications 8 (1) (2017)
Aifu Lin, Chunlai Li, Zhen Xing, Qingsong Hu, Ke Liang, Leng Han, Cheng Wang, David H Hawke, Shouyu Wang, Yanyan Zhang, Yongkun Wei, Guolin Ma, Peter K Park, Jianwei Zhou, Yan Zhou, Zhibin Hu, Yubin Zhou, Jeffery R Marks, Han Liang, Mien-Chie Hung, Chunru Lin, Liuqing Yang
The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. Nature cell biology 18 (2) (2016)
Xiaowen Liu, Zhen-Dong Xiao, Leng Han, Jiexin Zhang, Szu-Wei Lee, Wenqi Wang, Hyemin Lee, Li Zhuang, Junjie Chen, Hui-Kuan Lin, Jing Wang, Han Liang, Boyi Gan
LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nature cell biology 18 (4) (2016)
Yuan Yuan, Eliezer M Van Allen, Larsson Omberg, Nikhil Wagle, Ali Amin-Mansour, Artem Sokolov, Lauren A Byers, Yanxun Xu, Kenneth R Hess, Lixia Diao, Leng Han, Xuelin Huang, Michael S Lawrence, John N Weinstein, Josh M Stuart, Gordon B Mills, Levi A Garraway, Adam A Margolin, Gad Getz, Han Liang
Assessing the clinical utility of cancer genomic and proteomic data across tumor types. Nature biotechnology 32 (7) (2014)
S Nam, H R Chang, K-T Kim, M-C Kook, D Hong, C H Kwon, H R Jung, H S Park, G Powis, Han Liang, T Park, Y H Kim
PATHOME: an algorithm for accurately detecting differentially expressed subpathways. Oncogene 33 (41) (2014)